Are bone and serum cefazolin concentrations adequate for antimicrobial prophylaxis?

Clinical Orthopaedics and Related Research

Volumn 469, Issue 12, 2011, Pages 3486-3494

  Yamada, Koji ^a   Matsumoto, Kunihiro ^b   Tokimura, Fumiaki ^c   Okazaki, Hiroshi ^d   Tanaka, Sakae ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^c Tokyo Metropolitan Institute of Gerontology   (Japan)

^d TOKYO METROPOLITAN TAMA MEDICAL CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CEFAZOLIN;

AGED; ARTICLE; CLINICAL ARTICLE; COAGULASE NEGATIVE STAPHYLOCOCCUS; CROSS-SECTIONAL STUDY; DRUG BLOOD LEVEL; DRUG BONE LEVEL; FEMALE; HUMAN; HUMAN TISSUE; INFECTION PREVENTION; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SURGICAL INFECTION; SURGICAL SITE INFECTION; TOTAL HIP PROSTHESIS; TOTAL KNEE REPLACEMENT;

EID: 82655172344     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1007/s11999-011-2111-8     Document Type: Article

References (38)

1. GC Bannister JM Auchincloss DP Johnson JH Newman 1988 The timing of tourniquet application in relation to prophylactic antibiotic administration J Bone Joint Surg Br. 70 322 324 3346316 1:STN:280:DyaL1c7ltlyktQ%3D%3D
2. L Bernard C Sadowski D Monin R Stern B Wyssa P Rohner D Lew P Hoffmeyer 2004 The value of bacterial culture during clean orthopedic surgery: a prospective study of 1, 036 patients Infect Control Hosp Epidemiol. 25 512 514 15242201 10.1086/502431 (Pubitemid 38758498)
3. DW Bratzler PM Houck Surgical Infection Prevention Guidelines Writers Workgroup American Academy of Orthopaedic Surgeons American Association of Critical Care Nurses American Association of Nurse Anesthetists American College of Surgeons American College of Osteopathic Surgeons American Geriatrics Society American Society of Anesthesiologists American Society of Colon and Rectal Surgeons American Society of Health-System Pharmacists American Society of PeriAnesthesia Nurses Ascension Health Association of periOperative Registered Nurses Association for Professionals in Infection Control and Epidemiology Infectious Diseases Society of America Medical Letter Premier Society for Healthcare Epidemiology of America Society of Thoracic Surgeons Surgical Infection Society 2004 Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project Clin Infect Dis. 38 1706 1715 15227616 10.1086/421095 (Pubitemid 38781662)
4. Y Chang HN Shih DW Chen MS Lee SW Ueng PH Hsieh 2010 The concentration of antibiotic in fresh-frozen bone graft J Bone Joint Surg Br. 92 1471 1474 21089701 10.1302/0301-620X.92B10.24704 1:STN:280:DC%2BC3cboslehsg%3D%3D
5. NX Chin NM Neu HC Neu 1990 Activity of cephalosporins against coagulase-negative staphylococci Diagn Microbiol Infect Dis. 13 67 69 2331853 10.1016/0732-8893(90)90057-3 1:STN:280:DyaK3c3jsFGjsg%3D%3D (Pubitemid 20123154)
6. BA Cunha HR Gossling HS Pasternak CH Nightingale R Quintiliani 1977 The penetration characteristics of cefazolin, cephalothin, and cephradine into bone in patients undergoing total hip replacement J Bone Joint Surg Am. 59 856 859 908715 1:STN:280:DyaE1c%2FgsFGrsA%3D%3D (Pubitemid 8218238)
7. DJ Dalstrom I Venkatarayappa AL Manternach MS Palcic BA Heyse MJ Prayson 2008 Time-dependent contamination of opened sterile operating-room trays J Bone Joint Surg Am. 90 1022 1025 18451394 10.2106/JBJS.G.00689 (Pubitemid 351632646)
8. RO Darouiche 2004 Treatment of infections associated with surgical implants N Engl J Med. 350 1422 1429 15070792 10.1056/NEJMra035415 1:CAS:528:DC%2BD2cXivVagtrs%3D (Pubitemid 38419996)
9. N Fletcher D Sofianos MB Berkes WT Obremskey 2007 Prevention of perioperative infection J Bone Joint Surg Am. 89 1605 1618 17606802 10.2106/JBJS.F.00901 (Pubitemid 47041540)
10. RA Forse B Karam LD MacLean NV Christou 1989 Antibiotic prophylaxis for surgery in morbidly obese patients Surgery. 106 750 756 2799651 1:STN:280:DyaK3c%2FhvF2ktg%3D%3D discussion 756-757
11. RJ Friedman LV Friedrich RL White MB Kays DM Brundage J Graham 1990 Antibiotic prophylaxis and tourniquet inflation in total knee arthroplasty Clin Orthop Relat Res. 260 17 23 2121406 (Pubitemid 20381511)
12. LV Friedrich RL White DM Brundage MB Kays RJ Friedman 1990 The effect of tourniquet inflation on cefazolin tissue penetration during total knee arthroplasty Pharmacotherapy. 10 373 377 2287555 1:STN:280:DyaK3M7ktF2qtw%3D%3D
13. T Fujimura I Yoshida Y Itoh M Tachibana M Kaku K Kanemitsu C Takahashi J Shiotani Y Ono H Baba S Matsuo S Asari K Matsuoka N Kusano M Nose T Saikawa K Hiramatsu S Kohno Y Hirakata N Yamane I Nakasone Y Yamano 2008 Antimicrobial susceptibility of clinical isolates of aerobic Gram-positive cocci and anaerobic bacteria in 2004][in Japanese Jpn J Chemother. 56 543 561
14. E Garza-Gonzalez R Morfin-Otero JM Llaca-Diaz E Rodriguez-Noriega 2010 Staphylococcal cassette chromosome mec (SCC mec) in methicillin-resistant coagulase-negative staphylococci: a review and the experience in a tertiary-care setting Epidemiol Infect. 138 645 654 19961645 10.1017/S0950268809991361 1:STN:280:DC%2BC3c3hsFWmtw%3D%3D
15. S Irie M Terakawa K Ishibashi K Tabata S Suzuki Y Yokota 1999 Pharmacokinetic study of a parenteral cephalosporin, cefazolin in healthy volunteers given Cefamezin® -infusion 1-g kit][in Japanese Kagakuryouhou no Ryouiki. 15 766 774 1:CAS:528:DyaK1MXksVShsL0%3D
16. DP Johnson 1987 Antibiotic prophylaxis with cefuroxime in arthroplasty of the knee J Bone Joint Surg Br 69 787 789 3316240 1:STN:280: DyaL1c%2FlvFWqsA%3D%3D
17. Y Kimura K Nagano I Higashiyama Y Jinushi S Sasaki I Yoshida 1996 Surveillance of susceptibility of clinical isolates of various bacterial species to antibacterial agents -No.1 against Gram-positive cocci isolated in 1994][in Japanese Jpn J Chemother 44 595 609 (Pubitemid 26301480)
18. Y Kimura I Yoshida I Higashiyama K Nagano S Sasaki 1998 Surveillance of susceptibility of clinical isolates of various bacterial species to antibacterial agents -No.1 against Gram-positive cocci isolated in 1996][in Japanese Jpn J Chemother 46 324 342
19. AJ Mangram TC Horan ML Pearson LC Silver WR Jarvis 1999 Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee Infect Control Hosp Epidemiol. 20 250 278 10219875 10.1086/501620 1:STN:280:DyaK1M3jsFarsw%3D%3D quiz 279-280
20. E Moran S Masters AR Berendt P McLardy-Smith I Byren BL Atkins 2007 Guiding empirical antibiotic therapy in orthopaedics: the microbiology of prosthetic joint infection managed by debridement, irrigation and prosthesis retention J Infect. 55 1 7 17343916 10.1016/j.jinf.2007.01.007 1:STN:280:DC%2BD2szlsVGjtw%3D%3D (Pubitemid 46888074)
21. RS Nickinson TN Board AK Gambhir ML Porter PR Kay 2010 The microbiology of the infected knee arthroplasty Int Orthop. 34 505 510 19458950 10.1007/s00264-009-0797-y 1:STN:280:DC%2BC3c7pt1egtg%3D%3D
22. AD Oliveira PA d'Azevedo LB de Sousa C Viana-Niero W Francisco C Lottenberg MD Martino AL Hofling-Lima 2007 Laboratory detection methods for methicillin resistance in coagulase negative Staphylococcus isolated from ophthalmic infections Arq Bras Oftalmol. 70 667 675 17906764 10.1590/S0004-27492007000400018
23. DR Osmon 2002 Antimicrobial resistance: guidelines for the practicing orthopaedic surgeon Instr Course Lect. 51 527 537 12064143
24. RV Ostrander MJ Botte ME Brage 2005 Efficacy of surgical preparation solutions in foot and ankle surgery J Bone Joint Surg Am. 87 980 985 15866959 10.2106/JBJS.D.01977 (Pubitemid 40617564)
25. L Prokuski 2008 Prophylactic antibiotics in orthopaedic surgery J Am Acad Orthop Surg. 16 283 293 18460689
26. R Quintiliani C Nightingale 1984 Principles of antibiotic usage Clin Orthop Relat Res. 190 31 35 6488647 (Pubitemid 15223462)
27. I Raad A Alrahwan K Rolston 1998 Staphylococcus epidermidis: emerging resistance and need for alternative agents Clin Infect Dis. 26 1182 1187 9597250 10.1086/520285 1:STN:280:DyaK1c3lvFGgug%3D%3D (Pubitemid 28215486)
28. I Rafiq AK Gambhir BM Wroblewski PR Kay 2006 The microbiology of infected hip arthroplasty Int Orthop. 30 532 535 16896877 10.1007/s00264-006-0125-8 (Pubitemid 44900564)
29. V Saegeman D Lismont B Verduyckt N Ectors J Stuyck J Verhaegen 2007 Antimicrobial susceptibility of coagulase-negative staphylococci on tissue allografts and isolates from orthopedic patients J Orthop Res. 25 501 507 17143897 10.1002/jor.20212 1:CAS:528:DC%2BD2sXksVOls7k%3D (Pubitemid 46542038)
30. SI Savitz MH Savitz HB Goldstein CT Mouracade S Malangone 1998 Topical irrigation with polymyxin and bacitracin for spinal surgery Surg Neurol. 50 208 212 9736080 10.1016/S0090-3019(97)00499-0 1:STN:280:DyaK1cvgsFCrtQ%3D%3D (Pubitemid 28415575)
31. DJ Schurman HP Hirshman G Kajiyama K Moser DS Burton 1978 Cefazolin concentrations in bone and synovial fluid J Bone Joint Surg Am. 60 359 362 649639 1:STN:280:DyaE1c7ntFKisw%3D%3D (Pubitemid 8333077)
32. TS Sørensen H Colding E Schroeder VT Rosdahl 1978 The penetration of cefazolin, erythromycin and methicillin into human bone tissue Acta Orthop Scand. 49 549 553 735781 10.3109/17453677808993236 (Pubitemid 9103831)
33. JD Whitehouse ND Friedman KB Kirkland WJ Richardson DJ Sexton 2002 The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost Infect Control Hosp Epidemiol. 23 183 189 12002232 10.1086/502033 (Pubitemid 34297271)
34. Wikler MA, Cockerill FR, Craig WA, Dudley MN, Eliopoulos GM, Hecht DW, Hindler JF, Low DE, Sheehan DJ, Tenover FC, Turnidge JD, Weinstein MP, Zimmer BL, Ferraro MJ, Swenson JM. Performance Standards for Antimicrobial Susceptibility Testing; Fifteenth Informational Supplement. Wayne, PA: Clinical and Laboratory Standards Institute; 2005.
35. DN Williams RB Gustilo R Beverly AC Kind 1983 Bone and serum concentrations of five cephalosporin drugs: relevance to prophylaxis and treatment in orthopedic surgery Clin Orthop Relat Res. 179 253 265 6617025 10.1097/00003086-198310000-00039 (Pubitemid 13017335)
36. World Health Organization. WHO Guidelines for Safe Surgery: 2009: Safe Surgery Saves Lives. Available at: http://whqlibdoc.who.int/publications/2009/ 9789241598552-eng.pdf. Accessed November 18, 2010.
37. K Yamada H Okazaki T Iga I Nagai T Tatsumi C Touhara W Sato J Hasegawa S Tanaka K Matsudaira K Nakamura 2010 The surgical site is contaminated even in the clean orthopaedic surgery][in Japanese Nippon Seikeigeka Gakkai Zasshi. 84 S707
38. I Yoshida Y Kimura I Higashiyama G Sugimori Y Yamano 2003 Surveillance of susceptibility of clinical isolates of various bacterial species to antibacterial agents: antimicrobial activity against gram-positive cocci and anaerobic bacteria isolated in 2000][in Japanese] Jpn J Chemother. 51 179 208 (Pubitemid 36581839)