A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment

BMC Medicine

Volumn 12, Issue 1, 2014, Pages

  Nakagawa, Takayuki ^a   Kumakawa, Kozo ^d   Usami, Shin ichi ^e   Hato, Naohito ^f   Tabuchi, Keiji ^g   Takahashi, Mariko ^h   Fujiwara, Keizo ⁱ   Sasaki, Akira ^j   Komune, Shizuo ^k   Sakamoto, Tatsunori ^a   Hiraumi, Harukazu ^a   Yamamoto, Norio ^a   Tanaka, Shiro ^a   Tada, Harue ^a   Yamamoto, Michio ^a   Yonezawa, Atsushi ^c   Ito Ihara, Toshiko ^a   Ikeda, Takafumi ^a   Shimizu, Akira ^a   Tabata, Yasuhiko ^b   Ito, Juichi ^a   more..

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d Okinaka Memorial Institute for Medical Research   (Japan)

^e SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g UNIVERSITY OF TSUKUBA   (Japan)

^h NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

ⁱ KOBE CITY MEDICAL CENTER GENERAL HOSPITAL   (Japan)

^j HIROSAKI UNIVERSITY   (Japan)

^k KYUSHU UNIVERSITY   (Japan)

more..

Author keywords

Dexamethasone; Drug delivery system; IGF 1; Local application; Sudden sensorineural hearing loss

Indexed keywords

DEXAMETHASONE SODIUM PHOSPHATE; GELATIN; RECOMBINANT SOMATOMEDIN C; DEXAMETHASONE; GLUCOCORTICOID; SOMATOMEDIN C;

ADULT; ARTICLE; AUDITORY THRESHOLD; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SAFETY; EARDRUM PERFORATION; EXTERNAL OTITIS; FEMALE; HEARING; HUMAN; HYDROGEL; MAJOR CLINICAL STUDY; MALE; MIDDLE EAR; MULTICENTER STUDY; NAUSEA; OTITIS MEDIA; PERCEPTION DEAFNESS; PURE TONE AUDIOMETRY; RANDOMIZED CONTROLLED TRIAL; SUDDEN DEAFNESS; SYSTEMIC THERAPY; TINNITUS; TREATMENT DURATION; TREATMENT OUTCOME; VOMITING; CLINICAL TRIAL; EARDRUM; HEARING LOSS, SUDDEN; HEARING TEST; INTRAARTICULAR DRUG ADMINISTRATION; INTRADERMAL DRUG ADMINISTRATION; JAPAN; MIDDLE AGED; PATHOPHYSIOLOGY;

ADMINISTRATION, CUTANEOUS; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; HEARING LOSS, SUDDEN; HEARING TESTS; HUMANS; INJECTIONS, INTRA-ARTICULAR; INSULIN-LIKE GROWTH FACTOR I; JAPAN; MALE; MIDDLE AGED; TREATMENT OUTCOME; TYMPANIC MEMBRANE;

EID: 84922418862     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-014-0219-x     Document Type: Article

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