AAV-mediated and pharmacological induction of Hsp70 expression stimulates survival of retinal ganglion cells following axonal injury

Gene Therapy

Volumn 22, Issue 2, 2015, Pages 138-145

  Kwong, J M K ^a   Gu, L ^a   Nassiri, N ^a   Bekerman, V ^a   Kumar Singh, R ^b   Rhee, K D ^a   Yang, X J ^a   Hauswirth, W W ^c   Caprioli, J ^a   Piri, N ^a  

^a JULES STEIN EYE INSTITUTE   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 70; TANESPIMYCIN; BENZOQUINONE DERIVATIVE; MACROCYCLIC LACTAM;

ADULT; ANIMAL EXPERIMENT; ARTICLE; AXONAL INJURY; CELL COUNT; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; RETINA GANGLION CELL; UPREGULATION; ANIMAL; C57BL MOUSE; DEPENDOPARVOVIRUS; GENE THERAPY; GENETIC TRANSDUCTION; GENETICS; METABOLISM; MULTIMODALITY CANCER THERAPY; NERVE CRUSH; NERVE FIBER; NERVE REGENERATION; OPTIC NERVE INJURIES; PATHOLOGY; PHYSIOLOGY; RETINA; TRANSCRIPTION INITIATION;

ANIMALIA;

ANIMALS; AXONS; BENZOQUINONES; CELL SURVIVAL; COMBINED MODALITY THERAPY; DEPENDOVIRUS; GENETIC THERAPY; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MICE, INBRED C57BL; NERVE CRUSH; NERVE REGENERATION; OPTIC NERVE INJURIES; RETINA; RETINAL GANGLION CELLS; TRANSCRIPTIONAL ACTIVATION; TRANSDUCTION, GENETIC;

EID: 84922410804     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2014.105     Document Type: Article

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