메뉴 건너뛰기




Volumn 21, Issue 2, 2015, Pages 133-141

The chronic bronchitis phenotype in chronic obstructive pulmonary disease: Features and implications

Author keywords

airway disease; chronic bronchitis; chronic obstructive pulmonary disease; genetics; N Acetylcysteine

Indexed keywords

ANTIOXIDANT; MACROLIDE; PHOSPHODIESTERASE IV INHIBITOR;

EID: 84922400968     PISSN: 10705287     EISSN: 15316971     Source Type: Journal    
DOI: 10.1097/MCP.0000000000000145     Document Type: Review
Times cited : (69)

References (83)
  • 1
    • 84873956600 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • Vestbo J, Hurd SS, Agusti AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013; 187:347-365
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 347-365
    • Vestbo, J.1    Hurd, S.S.2    Agusti, A.G.3
  • 2
    • 0018081327 scopus 로고
    • EpiDemiology standardization project (American Thoracic Society)
    • Ferris BG. EpiDemiology standardization project (American Thoracic Society). Am Rev Respir Dis 1978; 118 (6 Pt 2):1-120
    • (1978) Am Rev Respir Dis , vol.118 , Issue.2-6 , pp. 1-120
    • Ferris, B.G.1
  • 3
    • 0029947193 scopus 로고    scopus 로고
    • Association of chronic mucus hypersecretion with FEV1 Decline and chronic obstructive pulmonary disease morbidity
    • Copenhagen City Heart Study Group
    • Vestbo J, Prescott E, Lange P. Association of chronic mucus hypersecretion with FEV1 Decline and chronic obstructive pulmonary disease morbidity. Copenhagen City Heart Study Group. Am J Respir Crit Care Med 1996; 153:1530-1535
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1530-1535
    • Vestbo, J.1    Prescott, E.2    Lange, P.3
  • 4
    • 33750048426 scopus 로고    scopus 로고
    • Thirty-year cumulative inciDence of chronic bronchitis and COPD in relation to 30-year pulmonary function and 40-year mortality: A follow-up in middle-Aged rural men
    • Pelkonen M, Notkola IL, Nissinen A, et al. Thirty-year cumulative inciDence of chronic bronchitis and COPD in relation to 30-year pulmonary function and 40-year mortality: a follow-up in middle-Aged rural men. Chest 2006; 130:1129-1137
    • (2006) Chest , vol.130 , pp. 1129-1137
    • Pelkonen, M.1    Notkola, I.L.2    Nissinen, A.3
  • 5
    • 70349694402 scopus 로고    scopus 로고
    • Chronic bronchitis before age 50 years predicts inciDent airflow limitation and mortality risk
    • Guerra S, Sherrill DL, Venker C, et al. Chronic bronchitis before age 50 years predicts inciDent airflow limitation and mortality risk. Thorax 2009; 64:894-900
    • (2009) Thorax , vol.64 , pp. 894-900
    • Guerra, S.1    Sherrill, D.L.2    Venker, C.3
  • 6
    • 80052690031 scopus 로고    scopus 로고
    • The chronic bronchitic phenotype of COPD: An analysis of the COPDGene study
    • Kim V, Han MK, Vance GB, et al. The chronic bronchitic phenotype of COPD: an analysis of the COPDGene study. Chest 2011; 140:626-633
    • (2011) Chest , vol.140 , pp. 626-633
    • Kim, V.1    Han, M.K.2    Vance, G.B.3
  • 7
    • 84863471264 scopus 로고    scopus 로고
    • Chronic cough and sputum production: A clinical COPD phenotype?
    • Burgel PR. Chronic cough and sputum production: a clinical COPD phenotype? Eur Respir J 2012; 40:4-6
    • (2012) Eur Respir J , vol.40 , pp. 4-6
    • Burgel, P.R.1
  • 8
    • 84908309402 scopus 로고    scopus 로고
    • Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene
    • Lee JH, Cho MH, McDonald ML, et al. Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene. Respir Med 2014; 108:1469-1480
    • (2014) Respir Med , vol.108 , pp. 1469-1480
    • Lee, J.H.1    Cho, M.H.2    McDonald, M.L.3
  • 9
    • 0024406878 scopus 로고
    • Chronic obstructive lung disease in Copenhagen: Cross-sectional epiDemiological aspects
    • Lange P, Groth S, Nyboe J, et al. Chronic obstructive lung disease in Copenhagen: Cross-sectional epiDemiological aspects. J Intern Med 1989; 226:25-32
    • (1989) J Intern Med , vol.226 , pp. 25-32
    • Lange, P.1    Groth, S.2    Nyboe, J.3
  • 10
    • 0032745868 scopus 로고    scopus 로고
    • Increasing prevalence of asthma but not of chronic bronchitis in Finland? Report from the FinEsS-Helsinki study
    • Pallasaho P, Lundback B, Laspa SL, et al. Increasing prevalence of asthma but not of chronic bronchitis in Finland? Report from the FinEsS-Helsinki study. Respir Med 1999; 93:798-809
    • (1999) Respir Med , vol.93 , pp. 798-809
    • Pallasaho, P.1    Lundback, B.2    Laspa, S.L.3
  • 11
    • 0034035120 scopus 로고    scopus 로고
    • Airway obstruction in relation to symptoms in chronic respiratory disease-A nationally representative population study
    • Von Hertzen L, Reunanen A, Impivaara O, et al. Airway obstruction in relation to symptoms in chronic respiratory disease-A nationally representative population study. Respir Med 2000; 94:356-363
    • (2000) Respir Med , vol.94 , pp. 356-363
    • Von Hertzen, L.1    Reunanen, A.2    Impivaara, O.3
  • 12
    • 0034906052 scopus 로고    scopus 로고
    • Variations in the prevalence across countries of chronic bronchitis and smoking habits in young adults
    • Cerveri I, Accordini S, Verlato G, et al. Variations in the prevalence across countries of chronic bronchitis and smoking habits in young adults. Eur Respir J 2001; 18:85-92
    • (2001) Eur Respir J , vol.18 , pp. 85-92
    • Cerveri, I.1    Accordini, S.2    Verlato, G.3
  • 13
    • 17944368370 scopus 로고    scopus 로고
    • Determinants of cough in young adults participating in the European Community Respiratory Health Survey
    • Janson C, Chinn S, Jarvis D, Burney P. Determinants of cough in young adults participating in the European Community Respiratory Health Survey. Eur Respir J 2001; 18:647-654
    • (2001) Eur Respir J , vol.18 , pp. 647-654
    • Janson, C.1    Chinn, S.2    Jarvis, D.3    Burney, P.4
  • 14
    • 0036796532 scopus 로고    scopus 로고
    • Chronic bronchitis among French adults: High prevalence and unDerdiagnosis
    • Huchon GJ, Vergnenegre A, Neukirch F, et al. Chronic bronchitis among French adults: high prevalence and unDerdiagnosis. Eur Respir J 2002; 20:806-812
    • (2002) Eur Respir J , vol.20 , pp. 806-812
    • Huchon, G.J.1    Vergnenegre, A.2    Neukirch, F.3
  • 15
    • 0345701470 scopus 로고    scopus 로고
    • Not 15 but 50% of smokers Develop COPD? Report from the obstructive lung disease in northern SweDen studies
    • Lundback B, Lindberg A, Lindstrom M, et al. Not 15 but 50% of smokers Develop COPD? Report from the obstructive lung disease in northern SweDen studies. Respir Med 2003; 97:115-122
    • (2003) Respir Med , vol.97 , pp. 115-122
    • Lundback, B.1    Lindberg, A.2    Lindstrom, M.3
  • 16
    • 33749362986 scopus 로고    scopus 로고
    • Chronic respiratory symptoms, spirometry and knowledge of COPD among general population
    • Miravitlles M, De La Roza C, Morera J, et al. Chronic respiratory symptoms, spirometry and knowledge of COPD among general population. Respir Med 2006; 100:1973-1980
    • (2006) Respir Med , vol.100 , pp. 1973-1980
    • Miravitlles, M.1    De La Roza, C.2    Morera, J.3
  • 17
    • 33846248798 scopus 로고    scopus 로고
    • InciDence of chronic obstructive pulmonary disease in a cohort of young adults according to the presence of chronic cough and phlegm
    • De Marco R, Accordini S, Cerveri I, et al. InciDence of chronic obstructive pulmonary disease in a cohort of young adults according to the presence of chronic cough and phlegm. Am J Respir Crit Care Med 2007; 175:32-39
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 32-39
    • De Marco, R.1    Accordini, S.2    Cerveri, I.3
  • 18
    • 70349667504 scopus 로고    scopus 로고
    • Prevalence of COPD in Spain: Impact of undiagnosed COPD on quality of life and daily life activities
    • Miravitlles M, Soriano JB, Garcia-Rio F, et al. Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities. Thorax 2009; 64:863-868
    • (2009) Thorax , vol.64 , pp. 863-868
    • Miravitlles, M.1    Soriano, J.B.2    Garcia-Rio, F.3
  • 19
    • 77954730879 scopus 로고    scopus 로고
    • Chronic mucus hypersecretion: Prevalence and risk factors in younger individuals
    • Harmsen L, Thomsen SF, Ingebrigtsen T, et al. Chronic mucus hypersecretion: Prevalence and risk factors in younger individuals. Int J Tuberc Lung Dis 2010; 14:1052-1058
    • (2010) Int J Tuberc Lung Dis , vol.14 , pp. 1052-1058
    • Harmsen, L.1    Thomsen, S.F.2    Ingebrigtsen, T.3
  • 20
    • 84896708355 scopus 로고    scopus 로고
    • The clinical impact of nonobstructive chronic bronchitis in current and former smokers
    • Martinez CH, Kim V, Chen Y, et al. The clinical impact of nonobstructive chronic bronchitis in current and former smokers. Respir Med 2014; 108:491-499
    • (2014) Respir Med , vol.108 , pp. 491-499
    • Martinez, C.H.1    Kim, V.2    Chen, Y.3
  • 21
    • 0347386288 scopus 로고    scopus 로고
    • EpiDemiological study of chronic obstructive pulmonary disease in Spain (IBERPOC): Prevalence of chronic respiratory symptoms and airflow limitation
    • Sobradillo V, Miravitlles M, Jimenez CA, et al. EpiDemiological study of chronic obstructive pulmonary disease in Spain (IBERPOC): Prevalence of chronic respiratory symptoms and airflow limitation. Arch Bronconeumol 1999; 35:159-166
    • (1999) Arch Bronconeumol , vol.35 , pp. 159-166
    • Sobradillo, V.1    Miravitlles, M.2    Jimenez, C.A.3
  • 22
    • 79959272070 scopus 로고    scopus 로고
    • Cough and sputum production as risk factors for poor outcomes in patients with COPD
    • Miravitlles M. Cough and sputum production as risk factors for poor outcomes in patients with COPD. Respir Med 2011; 105:1118-1128
    • (2011) Respir Med , vol.105 , pp. 1118-1128
    • Miravitlles, M.1
  • 23
    • 84922413397 scopus 로고    scopus 로고
    • American Lung Association Trends in COPD (chronic bronchitis and emphysema): morbidity and mortality
    • American Lung Association. Trends in COPD (chronic bronchitis and emphysema): morbidity and mortality. 2013; Accessed at www.lung.org/findingcures/our-research/trend-reports/copd-trend-report.pdf
    • (2013)
  • 24
    • 64749104557 scopus 로고    scopus 로고
    • Cough and sputum production are associated with frequent exacerbations and hospitalizations in COPD subjects
    • Burgel PR, Nesme-Meyer P, Chanez P, et al. Cough and sputum production are associated with frequent exacerbations and hospitalizations in COPD subjects. Chest 2009; 135:975-982
    • (2009) Chest , vol.135 , pp. 975-982
    • Burgel, P.R.1    Nesme-Meyer, P.2    Chanez, P.3
  • 25
    • 79551603829 scopus 로고    scopus 로고
    • Characterisation of COPD heterogeneity in the ECLIPSE cohort
    • Agusti A, Calverley PM, Celli B, et al. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res 2010; 11:122
    • (2010) Respir Res , vol.11 , pp. 122
    • Agusti, A.1    Calverley, P.M.2    Celli, B.3
  • 26
    • 84862491658 scopus 로고    scopus 로고
    • The chronic bronchitis phenotype in subjects with and without COPD: The PLATINO study
    • De Oca MM, Halbert RJ, Lopez MV, et al. The chronic bronchitis phenotype in subjects with and without COPD: The PLATINO study. Eur Respir J 2012; 40:28-36
    • (2012) Eur Respir J , vol.40 , pp. 28-36
    • De Oca, M.M.1    Halbert, R.J.2    Lopez, M.V.3
  • 27
    • 84903197851 scopus 로고    scopus 로고
    • Clinical and computed tomographic predictors of chronic bronchitis in COPD: A cross sectional analysis of the COPDGene study
    • Kim V, Davey A, Comellas AP, et al. Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study. Respir Res 2014; 15:52
    • (2014) Respir Res , vol.15 , pp. 52
    • Kim, V.1    Davey, A.2    Comellas, A.P.3
  • 28
    • 0025033561 scopus 로고
    • Relation of ventilatory impairment and of chronic mucus hypersecretion to mortality from obstructive lung disease and from all causes
    • Lange P, Nyboe J, Appleyard M, et al. Relation of ventilatory impairment and of chronic mucus hypersecretion to mortality from obstructive lung disease and from all causes. Thorax 1990; 45:579-585
    • (1990) Thorax , vol.45 , pp. 579-585
    • Lange, P.1    Nyboe, J.2    Appleyard, M.3
  • 29
    • 0024429642 scopus 로고
    • Chronic obstructive pulmonary disease mortality in six US cities
    • Speizer FE, Fay ME, Dockery DW, Ferris BG Jr. Chronic obstructive pulmonary disease mortality in six U.S. cities. Am Rev Respir Dis 1989; 140 (3 Pt 2):S49-55
    • (1989) Am Rev Respir Dis , vol.140 , Issue.2-3 , pp. S49-55
    • Speizer, F.E.1    Fay, M.E.2    Dockery, D.W.3    Ferris, B.G.4
  • 30
    • 77957278202 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease in the absence of chronic bronchitis in China
    • Lu M, Yao W, Zhong N, et al. Chronic obstructive pulmonary disease in the absence of chronic bronchitis in China. Respirology 2010; 15:1072-1078
    • (2010) Respirology , vol.15 , pp. 1072-1078
    • Lu, M.1    Yao, W.2    Zhong, N.3
  • 32
    • 77949363490 scopus 로고    scopus 로고
    • Genetic epidemiology of copd (copdgene) study design
    • Regan EA, Hokanson JE, Murphy JR, et al. Genetic epiDemiology of COPD (COPDGene) study Design. COPD 2010; 7:32-43
    • (2010) COPD , vol.7 , pp. 32-43
    • Regan, E.A.1    Hokanson, J.E.2    Murphy, J.R.3
  • 33
    • 84855903837 scopus 로고    scopus 로고
    • Chronic bronchitis in the general population: Influence of age, genDer and socio-economic conditions
    • Ferre A, Fuhrman C, Zureik M, et al. Chronic bronchitis in the general population: Influence of age, genDer and socio-economic conditions. Respir Med 2012; 106:467-471
    • (2012) Respir Med , vol.106 , pp. 467-471
    • Ferre, A.1    Fuhrman, C.2    Zureik, M.3
  • 34
    • 79958276531 scopus 로고    scopus 로고
    • Systematic review with meta-Analysis of the epiDemiological eviDence relating smoking to COPD, chronic bronchitis and emphysema
    • Forey BA, Thornton AJ, Lee PN. Systematic review with meta-Analysis of the epiDemiological eviDence relating smoking to COPD, chronic bronchitis and emphysema. BMC Pulm Med 2011; 11:36
    • (2011) BMC Pulm Med , vol.11 , pp. 36
    • Forey, B.A.1    Thornton, A.J.2    Lee, P.N.3
  • 35
    • 84898547349 scopus 로고    scopus 로고
    • Risk factors for chronic mucus hypersecretion in individuals with and without COPD: Influence of smoking and job exposure on CMH
    • Dijkstra AE, De Jong K, Boezen HM, et al. Risk factors for chronic mucus hypersecretion in individuals with and without COPD: Influence of smoking and job exposure on CMH. Occup Environ Med 2014; 71:346-352
    • (2014) Occup Environ Med , vol.71 , pp. 346-352
    • Dijkstra, A.E.1    De Jong, K.2    Boezen, H.M.3
  • 36
    • 84877136736 scopus 로고    scopus 로고
    • Predictors of objective cough frequency in chronic obstructive pulmonary disease
    • Sumner H, Woodcock A, Kolsum U, et al. Predictors of objective cough frequency in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2013; 187:943-949
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 943-949
    • Sumner, H.1    Woodcock, A.2    Kolsum, U.3
  • 37
    • 84873451654 scopus 로고    scopus 로고
    • Diverging trends of chronic bronchitis and smoking habits between 1998 and 2010
    • Accordini S, Corsico AG, Cerveri I, et al. Diverging trends of chronic bronchitis and smoking habits between 1998 and 2010. Respir Res 2013; 14:16
    • (2013) Respir Res , vol.14 , pp. 16
    • Accordini, S.1    Corsico, A.G.2    Cerveri, I.3
  • 38
    • 84895521518 scopus 로고    scopus 로고
    • Lifetime occupational exposure to dusts, gases and fumes is associated with bronchitis symptoms and higher diffusion capacity in COPD patients
    • Rodriguez E, Ferrer J, Zock JP, et al. Lifetime occupational exposure to dusts, gases and fumes is associated with bronchitis symptoms and higher diffusion capacity in COPD patients. PLoS One 2014; 9:e88426
    • (2014) PLoS One , vol.9 , pp. e88426
    • Rodriguez, E.1    Ferrer, J.2    Zock, J.P.3
  • 39
    • 84922413396 scopus 로고    scopus 로고
    • Association between occupational exposure and lung function, respiratory symptoms and high resolution CT imaging in COPDGene
    • Marchetti N, Garshick E, Kinney GL, et al. Association between occupational exposure and lung function, respiratory symptoms and high resolution CT imaging in COPDGene. Am J Respir Crit Care Med 2014; 190:756-762
    • (2014) Am J Respir Crit Care Med , vol.190 , pp. 756-762
    • Marchetti, N.1    Garshick, E.2    Kinney, G.L.3
  • 40
    • 84922398456 scopus 로고    scopus 로고
    • Clinical characteristics of patients with biomass smoke-Associated COPD and chronic bronchitis 2004-2014
    • Perez-Padilla R, Ramirez-Venegas A, Sansores R. Clinical characteristics of patients with biomass smoke-Associated COPD and chronic bronchitis, 2004-2014. J COPD Found 2014; 1:23-32
    • (2014) J COPD Found , vol.1 , pp. 23-32
    • Perez-Padilla, R.1    Ramirez-Venegas, A.2    Sansores, R.3
  • 41
    • 84895525357 scopus 로고    scopus 로고
    • COPD phenotypes in biomass smoke-versus tobacco smoke-exposed Mexican women
    • Camp PG, Ramirez-Venegas A, Sansores RH, et al. COPD phenotypes in biomass smoke-versus tobacco smoke-exposed Mexican women. Eur Respir J 2014; 43:725-734
    • (2014) Eur Respir J , vol.43 , pp. 725-734
    • Camp, P.G.1    Ramirez-Venegas, A.2    Sansores, R.H.3
  • 42
    • 84877723452 scopus 로고    scopus 로고
    • Tomographic and functional findings in severe COPD: Comparison between the wood smoke-related and smoking-related disease
    • Gonzalez-Garcia M, Maldonado Gomez D, Torres-Duque CA, et al. Tomographic and functional findings in severe COPD: Comparison between the wood smoke-related and smoking-related disease. J Bras Pneumol 2013; 39:147-154
    • (2013) J Bras Pneumol , vol.39 , pp. 147-154
    • Gonzalez-Garcia, M.1    Maldonado Gomez, D.2    Torres-Duque, C.A.3
  • 43
    • 84877713477 scopus 로고    scopus 로고
    • Pulmonary changes on HRCT scans in nonsmoking females with COPD due to wood smoke exposure
    • Moreira MA, Barbosa MA, Queiroz MC, et al. Pulmonary changes on HRCT scans in nonsmoking females with COPD due to wood smoke exposure. J Bras Pneumol 2013; 39:155-163
    • (2013) J Bras Pneumol , vol.39 , pp. 155-163
    • Moreira, M.A.1    Barbosa, M.A.2    Queiroz, M.C.3
  • 44
    • 9044240863 scopus 로고    scopus 로고
    • Committee of the environmental and occupational health assembly of the American Thoracic Society Health effects of outdoor air pollution
    • Committee of the Environmental and Occupational Health Assembly of the American Thoracic Society. Health effects of outdoor air pollution. Am J Respir Crit Care Med 1996; 153:3-50
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 3-50
  • 45
    • 84901701237 scopus 로고    scopus 로고
    • Projections of future summertime ozone over the U.S
    • Pfister GG, Walters S, Lamarque JF, et al. Projections of future summertime ozone over the U.S. Am Geophys Union 2014; 119: 5559-5582
    • (2014) Am Geophys Union , vol.119 , pp. 5559-5582
    • Pfister, G.G.1    Walters, S.2    Lamarque, J.F.3
  • 46
    • 84898823374 scopus 로고    scopus 로고
    • Ambient ozone and emergency Department visits due to lower respiratory condition
    • Kousha T, Rowe BH. Ambient ozone and emergency Department visits due to lower respiratory condition. Int J Occup Med Environ Health 2014; 27:50-59
    • (2014) Int J Occup Med Environ Health , vol.27 , pp. 50-59
    • Kousha, T.1    Rowe, B.H.2
  • 47
    • 84902259331 scopus 로고    scopus 로고
    • EpiDemiological time series studies of PM2.5 and daily mortality and hospital admissions: A systematic review and meta-Analysis
    • Atkinson RW, Kang S, AnDerson HR, et al. EpiDemiological time series studies of PM2.5 and daily mortality and hospital admissions: a systematic review and meta-Analysis. Thorax 2014; 69:660-665
    • (2014) Thorax , vol.69 , pp. 660-665
    • Atkinson, R.W.1    Kang, S.2    Anderson, H.R.3
  • 48
    • 84907316702 scopus 로고    scopus 로고
    • Air pollution and biomarkers of systemic inflammation and tissue repair in COPD patients
    • DadVand P, Nieuwenhuijsen MJ, Agust A, et al. Air pollution and biomarkers of systemic inflammation and tissue repair in COPD patients. Eur Respir J 2014; 44:603-613
    • (2014) Eur Respir J , vol.44 , pp. 603-613
    • Dadvand, P.1    Nieuwenhuijsen, M.J.2    Agust, A.3
  • 49
    • 84922407374 scopus 로고    scopus 로고
    • Clinical and radiographic characteristics of COPD with and without chronic bronchitis [abstract]
    • Kim V, Martinez FJ, Han MK, Criner GJ. Clinical and radiographic characteristics of COPD with and without chronic bronchitis [abstract]. Am J Respir Crit Care Med 2014; A5931
    • (2014) Am J Respir Crit Care Med , pp. A5931
    • Kim, V.1    Martinez, F.J.2    Han, M.K.3    Criner, G.J.4
  • 50
    • 84907891191 scopus 로고    scopus 로고
    • Cross-sectional associations between air pollution and chronic bronchitis: An ESCAPE meta-Analysis across five cohorts
    • Cai Y, Schikowski T, Adam M, et al. Cross-sectional associations between air pollution and chronic bronchitis: an ESCAPE meta-Analysis across five cohorts. Thorax 2014; 69:1005-1014
    • (2014) Thorax , vol.69 , pp. 1005-1014
    • Cai, Y.1    Schikowski, T.2    Adam, M.3
  • 51
    • 84881158540 scopus 로고    scopus 로고
    • Effects of allergic phenotype on respiratory symptoms and exacerbations in patients with chronic obstructive pulmonary disease
    • Jamieson DB, Matsui EC, Belli A, et al. Effects of allergic phenotype on respiratory symptoms and exacerbations in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2013; 188:187-192
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 187-192
    • Jamieson, D.B.1    Matsui, E.C.2    Belli, A.3
  • 52
    • 84913609662 scopus 로고    scopus 로고
    • Heredity of chronic bronchitis: A registrybased twin study
    • Meteran H, Backer V, Kyvik KO, et al. Heredity of chronic bronchitis: a registrybased twin study. Respir Med 2014; 108:1321-1326
    • (2014) Respir Med , vol.108 , pp. 1321-1326
    • Meteran, H.1    Backer, V.2    Kyvik, K.O.3
  • 53
    • 84899579701 scopus 로고    scopus 로고
    • Susceptibility to chronic mucus hypersecretion: A genome wiDe association study
    • Dijkstra AE, Smolonska J, Van Den Berge M, et al. Susceptibility to chronic mucus hypersecretion: a genome wiDe association study. PLoS One 2014; 9:e91621
    • (2014) PLoS One , vol.9 , pp. e91621
    • Dijkstra, A.E.1    Smolonska, J.2    Van Den Berge, M.3
  • 54
    • 84964698771 scopus 로고    scopus 로고
    • Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease
    • Lee J, Cho MH, Hersh CP, et al. Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. Respir Res 2014; 15:113
    • (2014) Respir Res , vol.15 , pp. 113
    • Lee, J.1    Cho, M.H.2    Hersh, C.P.3
  • 55
    • 12344263724 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Thin-section CT measurement of airway wall thickness and lung attenuation
    • Orlandi I, Moroni C, Camiciottoli G, et al. Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation. Radiology 2005; 234:604-610
    • (2005) Radiology , vol.234 , pp. 604-610
    • Orlandi, I.1    Moroni, C.2    Camiciottoli, G.3
  • 56
    • 84883494320 scopus 로고    scopus 로고
    • Pulmonary function and sputum characteristics predict computed tomography phenotype and severity of COPD
    • Camiciottoli G, Bigazzi F, Paoletti M, et al. Pulmonary function and sputum characteristics predict computed tomography phenotype and severity of COPD. Eur Respir J 2013; 42:626-635
    • (2013) Eur Respir J , vol.42 , pp. 626-635
    • Camiciottoli, G.1    Bigazzi, F.2    Paoletti, M.3
  • 57
    • 0026673538 scopus 로고
    • Longitudinal lung function Decline in subjects with respiratory symptoms
    • Sherman CB, Xu X, Speizer FE, et al. Longitudinal lung function Decline in subjects with respiratory symptoms. Am Rev Respir Dis 1992; 146:855-859
    • (1992) Am Rev Respir Dis , vol.146 , pp. 855-859
    • Sherman, C.B.1    Xu, X.2    Speizer, F.E.3
  • 58
    • 33645986683 scopus 로고    scopus 로고
    • Seven-year cumulative inciDence of COPD in an age-stratified general population sample
    • Lindberg A, Eriksson B, Larsson LG, et al. Seven-year cumulative inciDence of COPD in an age-stratified general population sample. Chest 2006; 129:879-885
    • (2006) Chest , vol.129 , pp. 879-885
    • Lindberg, A.1    Eriksson, B.2    Larsson, L.G.3
  • 59
    • 84888052047 scopus 로고    scopus 로고
    • Chronic bronchitis in COPD patients is associated with increased risk of exacerbations: A cross-sectional multicentre study
    • Corhay JL, Vincken W, Schlesser M, et al. Chronic bronchitis in COPD patients is associated with increased risk of exacerbations: a cross-sectional multicentre study. Int J Clin Pract 2013; 67:1294-1301
    • (2013) Int J Clin Pract , vol.67 , pp. 1294-1301
    • Corhay, J.L.1    Vincken, W.2    Schlesser, M.3
  • 60
    • 0022453116 scopus 로고
    • Is respiratory mucus hypersecretion really an innocent disorDer? A 22-year mortality survey of 1, 061 working men
    • Annesi I, Kauffmann F. Is respiratory mucus hypersecretion really an innocent disorDer? A 22-year mortality survey of 1, 061 working men. Am Rev Respir Dis 1986; 134:688-693
    • (1986) Am Rev Respir Dis , vol.134 , pp. 688-693
    • Annesi, I.1    Kauffmann, F.2
  • 61
    • 0024432236 scopus 로고
    • Respiratory risk factors and mortality: Longitudinal studies in Washington county
    • Tockman MS, Comstock GW. Respiratory risk factors and mortality: longitudinal studies in Washington county, Maryland. Am Rev Respir Dis 1989; 140 (3 Pt 2):S56-63
    • (1989) Maryland. Am Rev Respir Dis , vol.140 , Issue.2-3 , pp. S56-63
    • Tockman, M.S.1    Comstock, G.W.2
  • 62
    • 0029150812 scopus 로고
    • Chronic mucus hypersecretion in COPD and Death from pulmonary infection
    • Prescott E, Lange P, Vestbo J. Chronic mucus hypersecretion in COPD and Death from pulmonary infection. Eur Respir J 1995; 8:1333-1338
    • (1995) Eur Respir J , vol.8 , pp. 1333-1338
    • Prescott, E.1    Lange, P.2    Vestbo, J.3
  • 63
    • 0038752573 scopus 로고    scopus 로고
    • Lung function and mortality in the United States: Data from the first National Health and Nutrition Examination Survey follow up study
    • Mannino DM, Buist AS, Petty TL, et al. Lung function and mortality in the United States: data from the first National Health and Nutrition Examination Survey follow up study. Thorax 2003; 58:388-393
    • (2003) Thorax , vol.58 , pp. 388-393
    • Mannino, D.M.1    Buist, A.S.2    Petty, T.L.3
  • 65
    • 77956689733 scopus 로고    scopus 로고
    • Susceptibility to exacerbation in chronic obstructive pulmonary disease
    • Hurst JR, Vestbo J, Anzueto A, et al. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med 2010; 363:1128-1138
    • (2010) N Engl J Med , vol.363 , pp. 1128-1138
    • Hurst, J.R.1    Vestbo, J.2    Anzueto, A.3
  • 66
    • 84904036299 scopus 로고    scopus 로고
    • Exacerbation-like respiratory symptoms in individuals without chronic obstructive pulmonary disease: Results from a population-based study
    • Tan WC, Bourbeau J, HernanDez P, et al. Exacerbation-like respiratory symptoms in individuals without chronic obstructive pulmonary disease: results from a population-based study. Thorax 2014; 69:709-717
    • (2014) Thorax , vol.69 , pp. 709-717
    • Tan, W.C.1    Bourbeau, J.2    Hernandez, P.3
  • 67
    • 84870645803 scopus 로고    scopus 로고
    • Nonobstructive chronic bronchitis in the COPDGene cohort [abstract]
    • Martinez C, Chen Y, Kazerooni E, et al. Nonobstructive chronic bronchitis in the COPDGene cohort [abstract]. Am J Respir Crit Care Med 2012; A6622
    • Am J Respir Crit Care Med , vol.2012 , pp. A6622
    • Martinez, C.1    Chen, Y.2    Kazerooni, E.3
  • 68
    • 84907942900 scopus 로고    scopus 로고
    • Prediction of acute respiratory disease in current and former smokers with and without COPD
    • Bowler RP, Kim V, Regan E, et al. Prediction of acute respiratory disease in current and former smokers with and without COPD. Chest 2014; 146:941-950
    • (2014) Chest , vol.146 , pp. 941-950
    • Bowler, R.P.1    Kim, V.2    Regan, E.3
  • 69
    • 84870629633 scopus 로고    scopus 로고
    • Significance of chronic bronchitis in the COPD CRN azithromycin in COPD study [abstract]
    • Han MK, Kim V, Martinez C, et al. Significance of chronic bronchitis in the COPD CRN azithromycin in COPD study [abstract]. Am J Respir Crit Care Med 2012; A3736
    • Am J Respir Crit Care Med , vol.2012 , pp. A3736
    • Han, M.K.1    Kim, V.2    Martinez, C.3
  • 70
    • 84887976747 scopus 로고    scopus 로고
    • Severe chronic bronchitis in adVanced emphysema increases mortality and hospitalizations
    • Kim V, Sternberg AL, Washko G, et al. Severe chronic bronchitis in adVanced emphysema increases mortality and hospitalizations. COPD 2013; 10:667-678
    • (2013) COPD , vol.10 , pp. 667-678
    • Kim, V.1    Sternberg, A.L.2    Washko, G.3
  • 71
    • 84873353231 scopus 로고    scopus 로고
    • Chronic bronchitis and chronic obstructive pulmonary disease
    • Kim V, Criner GJ. Chronic bronchitis and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2013; 187:228-237
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 228-237
    • Kim, V.1    Criner, G.J.2
  • 72
    • 84876229373 scopus 로고    scopus 로고
    • Exacerbations among chronic bronchitis patients treated with maintenance medications from a US managed care population: An administrative claims data analysis
    • Abudagga A, Sun SX, Tan H, Solem CT. Exacerbations among chronic bronchitis patients treated with maintenance medications from a US managed care population: An administrative claims data analysis. Int J Chron Obstruct Pulmon Dis 2013; 8:175-185
    • (2013) Int J Chron Obstruct Pulmon Dis , vol.8 , pp. 175-185
    • Abudagga, A.1    Sun, S.X.2    Tan, H.3    Solem, C.T.4
  • 73
    • 84878665825 scopus 로고    scopus 로고
    • Nonantibiotic macroliDes prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume Depletion
    • Tarran R, Sabater JR, Clarke TC, et al. Nonantibiotic macroliDes prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume Depletion. Am J Physiol Lung Cell Mol Physiol 2013; 304:L746-L756
    • (2013) Am J Physiol Lung Cell Mol Physiol , vol.304 , pp. L746-L756
    • Tarran, R.1    Sabater, J.R.2    Clarke, T.C.3
  • 74
    • 56749157688 scopus 로고    scopus 로고
    • Long-term erythromycin therapy is associated with Decreased chronic obstructive pulmonary disease exacerbations
    • Seemungal TA, Wilkinson TM, Hurst JR, et al. Long-term erythromycin therapy is associated with Decreased chronic obstructive pulmonary disease exacerbations. Am J Respir Crit Care Med 2008; 178:1139-1147
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 1139-1147
    • Seemungal, T.A.1    Wilkinson, T.M.2    Hurst, J.R.3
  • 75
    • 80052157895 scopus 로고    scopus 로고
    • Azithromycin for prevention of exacerbations of COPD
    • Albert RK, Connett J, Bailey WC, et al. Azithromycin for prevention of exacerbations of COPD. N Engl J Med 2011; 365:689-698
    • (2011) N Engl J Med , vol.365 , pp. 689-698
    • Albert, R.K.1    Connett, J.2    Bailey, W.C.3
  • 76
    • 84902665590 scopus 로고    scopus 로고
    • Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy
    • HanMK, Tayob N, Murray S, et al. Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. Am J Respir Crit Care Med 2014; 189:1503-1508
    • (2014) Am J Respir Crit Care Med , vol.189 , pp. 1503-1508
    • Hanmk Tayob, N.1    Murray, S.2
  • 77
    • 84881494429 scopus 로고    scopus 로고
    • Acquired cystic fibrosis transmembrane conductance regulator dysfunction in the lower airways in COPD
    • Dransfield MT, Wilhelm AM, Flanagan B, et al. Acquired cystic fibrosis transmembrane conductance regulator dysfunction in the lower airways in COPD. Chest 2013; 144:498-506
    • (2013) Chest , vol.144 , pp. 498-506
    • Dransfield, M.T.1    Wilhelm, A.M.2    Flanagan, B.3
  • 78
    • 84895532370 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis
    • Lambert JA, Raju SV, Tang LP, et al. Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis. Am J Respir Cell Mol Biol 2014; 50:549-558
    • (2014) Am J Respir Cell Mol Biol , vol.50 , pp. 549-558
    • Lambert, J.A.1    Raju, S.V.2    Tang, L.P.3
  • 79
    • 69149098943 scopus 로고    scopus 로고
    • Roflumilast in moDerateto-severe chronic obstructive pulmonary disease treated with long acting bronchodilators: Two randomised clinical trials
    • Fabbri LM, Calverley PM, Izquierdo-Alonso JL, et al. Roflumilast in moDerateto-severe chronic obstructive pulmonary disease treated with long acting bronchodilators: two randomised clinical trials. Lancet 2009; 374:695-703
    • (2009) Lancet , vol.374 , pp. 695-703
    • Fabbri, L.M.1    Calverley, P.M.2    Izquierdo-Alonso, J.L.3
  • 80
    • 20944433417 scopus 로고    scopus 로고
    • Effects of Nacetylcysteine on outcomes in chronic obstructive pulmonary disease (bronchitis randomized on NAC cost-utility study, BRONCUS): A randomised placebo-controlled trial
    • Decramer M, Rutten-Van Molken M, Dekhuijzen PN, et al. Effects of Nacetylcysteine on outcomes in chronic obstructive pulmonary disease (bronchitis randomized on NAC cost-utility study, BRONCUS): a randomised placebo-controlled trial. Lancet 2005; 365:1552-1560
    • (2005) Lancet , vol.365 , pp. 1552-1560
    • Decramer, M.1    Rutten-Van Molken, M.2    Dekhuijzen, P.N.3
  • 81
    • 44849100529 scopus 로고    scopus 로고
    • Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE study): A randomised placebo-controlled study
    • Zheng JP, Kang J, Huang SG, et al. Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE study): a randomised placebo-controlled study. Lancet 2008; 371:2013-2018
    • (2008) Lancet , vol.371 , pp. 2013-2018
    • Zheng, J.P.1    Kang, J.2    Huang, S.G.3
  • 82
    • 84880047842 scopus 로고    scopus 로고
    • High-dose N-Acetylcysteine in stable COPD: The 1-year, double-blind, randomized, placebo-controlled HIACE study
    • Tse HN, Raiteri L, Wong KY, et al. High-dose N-Acetylcysteine in stable COPD: the 1-year, double-blind, randomized, placebo-controlled HIACE study. Chest 2013; 144:106-118
    • (2013) Chest , vol.144 , pp. 106-118
    • Tse, H.N.1    Raiteri, L.2    Wong, K.Y.3
  • 83
    • 84895803870 scopus 로고    scopus 로고
    • Twice daily N-Acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): A randomised, double-blind placebo-controlled trial
    • Zheng JP, Wen FQ, Bai CX, et al. Twice daily N-Acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial. Lancet Respir Med 2014; 2:187-194
    • (2014) Lancet Respir Med , vol.2 , pp. 187-194
    • Zheng, J.P.1    Wen, F.Q.2    Bai, C.X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.