Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene

Respiratory Medicine

Volumn 108, Issue 10, 2014, Pages 1469-1480

  Lee, Jin Hwa ^a,b   Cho, Michael H ^a   McDonald, Merry Lynn N ^a   Hersh, Craig P ^a   Castaldi, Peter J ^a   Crapo, James D ^c   Wan, Emily S ^a   Dy, Jennifer G ^d   Chang, Yale ^d   Regan, Elizabeth A ^c   Hardin, Megan ^a   Demeo, Dawn L ^a   Silverman, Edwin K ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Ewha Womans University School of Medicine   (South Korea)

^c UNIVERSITY OF COLORADO   (United States)

^d Northeastern University   (United States)

Author keywords

Chronic obstructive; Cluster analysis; Genetic association; Population characteristics; Pulmonary disease

Indexed keywords

CORTICOSTEROID; TIOTROPIUM BROMIDE;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; FEMALE; FORCED EXPIRATORY VOLUME; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; HUMAN; LUNG EMPHYSEMA; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY (TOPIC); PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SPIROMETRY; COMPLICATION; EPIDEMIOLOGY; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; RISK FACTOR; VERY ELDERLY;

AGED; AGED, 80 AND OVER; FEMALE; FORCED EXPIRATORY VOLUME; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RISK FACTORS; SMOKING; SPIROMETRY;

EID: 84908309402     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2014.07.018     Document Type: Article

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