MSCs as therapeutics

Mesenchymal Stromal Cells: Biology and Clinical Applications

Volumn , Issue , 2013, Pages 79-90

  Caplan, Arnold I ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84922395966     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-5711-4_5     Document Type: Chapter

References (55)

1. Thomas ED, Blume KG (1999) Historical markers in the development of allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 5(6):341-346
2. Weiss L (1976) The hematopoietic microenvironment of the bone marrow: an Ultrastructural study of the stroma in rats. Anat Rec 186(2):161-184
3. Charbord AP, Tavian M, Humeau L, Peault B (1996) Early ontogeny of the human marrow from long bones: an immunohistochemical stud of hematopoiesis and its microenvironment. Blood 87(10):4109-4119
4. Caplan AI (1984) Cartilage. Sci Am 251(4):84-94
5. Caplan AI, Fiszman MY, Eppenberger HM (1983) Molecular and cell isoforms during development. Science 221(4614):921-927
6. Caplan AI (1988) Biomaterials and bone repair. Biomaterials 87:15-24
7. Caplan AI (1991) Mesenchymal stem cells. J Orthop Res 9(5):641-650
8. Caplan AI (1994) The mesengenic process. Clin Plast Surg 21(3):429-435
9. Connolly JF (1998) Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis. Clin Orthop Relat Res 355:S257-S266
10. Caplan AI (2008) All MSCs are pericytes? Cell Stem Cell 3:229-230
11. Friedenstein AJ, Petrakova KV, Kurolesova AL, Frolova GP (1968) Heterotopic of bone marrow analysis of precursor cells for osteogenic and hematopoietic tissues. Transplantation 6(2):230-247
12. Owen M, Friedenstein AJ (1988) Stromal stem cells: marrow-derived osteogenic precursors. Ciba Found Symp 136:42-60
13. Caplan AI (1987) Bone development and repair. Bioessays 6(4):171-175
14. Caplan AI, Pechak DG (1987) The cellular and molecular embryology of bone formation. In: Peck WA (ed) Bone and mineral research, vol 5. Elsevier, New York
15. Bruder SP, Caplan AI (1990) Osteogenic cell lineage analysis is facilitated by organ culture of embryonic chick periosteum. Dev Biol 141(2):319-329
16. Lindholm TS, Urist MR (1980) A quantitative analysis of new bone formation by induction in compositive grafts of bone. Marrow and bone matrix. Clin Orthop Relat Res 150:288-300
17. Urist MR, DeLange RJ, Finerman GA (1983) Bone cell differentiation and growth factors. Science 220:680-686
18. Caplan AI (1990) Cartilage begets bone versus endochondral myelopoiesis. Clin Orthop Relat Res 261:257-267
19. Reddi AH (1981) Cell biology and biochemistry of endochondral bone development. Coll Relat Res 1(2):209-226
20. Owen M (1985) Lineage of osteogenic cells and their relationship to the stromal system. In: Peck WA (ed) Bone and mineral research, vol 3. Excerpta Medica, Amsterdam, pp 1-25
21. Mackay DL, Tesar PJ, Liang LN, Haynesworth SE (2006) Characterizing medullary and human mesenchymal stem cell-derived adipocytes. J Cell Physiol 207(3):722-728
22. Bruder SP, Fink DJ, Caplan AI (1994) Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration. J Cell Biochem 56(3):283-294
23. Haynesworth SE, Goshima J, Goldberg VM, Caplan AI (1992) Characterization of cells with osteogenic potential from human marrow. Bone 13(1):81-88
24. Nakahara H, Goldberg VM, Caplan AI (1991) Culture-expanded human periosteal-derived cells exhibit osteochondral potential in vivo. J Orthop Res 9(4):465-476
25. Nishimura K, Solchaga LA, Caplan AI, Yoo JU, Goldberg VM, Johnstone B (1999) Chondroprogenitor cells of synovial tissue. Arthritis Rheum 42(12):2631-2637
26. Goshima J, Goldberg VM, Caplan AI (1991) Osteogenic potential of culture-expanded rat marrow cells as assayed in vivo with porous calcium phosphate ceramic. Biomaterials 12:253-258
27. Bruder SP, Caplan AI (2000) Bone regeneration through cellular engineering. In: Lanza R, Langer R, Vancanti J (eds) Principles in tissue engineering, 2nd edn. Springer, New York, pp 683-696
28. Yoo JU, Barthel TS, Nishimura K, Solchaga L, Caplan AI, Goldberg VM et al (1998) The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J Bone Joint Surg Am 80(12):1745-1757
29. Wakitani S, Saito T, Caplan AI (1995) Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve 18:1417-1426
30. Majumdar MK, Thiede MA, Mosca JD, Moorman M, Gerson SL (1998) Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells. J Cell Physiol 176(1):57-66
31. Young RG, Butler DL, Weber W, Caplan AI, Gordon SL, Fink DJ (1998) Use of mesenchymal stem cells in Achilles tendon repair. J Orthop Res 16(4):406-413
32. Lazarus HM, Haynesworth SE, Gerson SL, Rosenthal NS, Caplan AI (1995) Ex-vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells) (MPCs): implications for therapeutic use. Bone Marrow Transplant 16(4):557-564
33. Koc ON, Gerson SL, Cooper BW, Dyhouse SM, Haynesworth SE, Caplan AI et al (2000) Rapid hematopoietic recovery after co-infusion of autologous blood stem cells and culture expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high dose chemotherapy. J Clin Oncol 18:307-316
34. Haynesworth SE, Baber MA, Caplan AI (1996) Cytokine expression by human marrow- derived mesenchymal progenitor cells in vitro: effects of dexamethasone and il-1a. J Cell Physiol 166(3):585-592
35. Carrino DA, Rodriguez JP, Caplan AI (1997) Dermatan sulfate proteoglycans from the mineralized matrix of the avian eggshell. Connect Tissue Res 36(3):175-193
36. Caplan AI (2003) Design parameters for functional tissue engineering. In: Guilak F, Butler DL, Goldstein SA, Mooney DJ (eds) Functional tissue engineering. Springer, New York
37. Lee JY, Qu-Petersen Z, Cao B, Kimura S, Jankowski R, Cummins J et al (2000) Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing. J Cell Biol 150(5):1085-1100
38. Kuroda R, Usas A, Kubo S, Corsi K, Peng H, Rose T et al (2006) Cartilage repair using bone morphogenetic protein 4 and muscle derived stem cells. Arthritis Rheum 54(2):433-442
39. Crisan M, Deasy B, Gavina J, Zheng B, Huard J, Lazzari L et al (2008) Purification and longterm culture of multipotent progenitor cells affiliated with the walls of human blood vessels: myoendothelial cells and pericytes. Methods Cell Biol 86:295-309
40. Sacchetti B, Funari A, Michienzi S, DiCesare S, Piersanti S, Saggio I et al (2007) Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 131(2):324-336
41. Crisan M, Yap S, Casteilla L, Chen CW, Corselli M, Park TS et al (2008) A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 3(3):301-313
42. Meirelles LDS, Fontes AM, Covas DT, Caplan AI (2009) Mechanisms involved in the therapeutic properties of mesenchymal stem cells. Cytokine Growth Factor Rev 20(5-6):419-427
43. Meirelles LDS, Caplan AI, Nardi NB (2008) In search of the in vivo identity of mesenchymal stem cells. Stem Cells 26(9):2287-2299
44. Estes BT, Wu AW, Guilak F (2006) Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6. Arthritis Rheum 54(4):1222-1232
45. Traktuev DO, Merfeld-Clauss S, Li J, Kolonin M, Arap W, Pasqualini R et al (2008) A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ Res 102(1):77-85
46. In't Anker PS, Scherion SA, Kleijburg-vander Keur C, de Goot-Swings GM, Claas FH, Fibbe WE (2004) Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells 22(7):1338-1346
47. Kern S, Eichler H, Stoeve J, Kluter H, Bieback K (2006) Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 24(5): 1294-1301
48. Osiris Therapeutics, Inc. [Internet]. http://www.osiris.com/, Accessed January 2012
49. Caplan AI, Dennis JE (2006) Mesenchymal stem cells as trophic mediators. J Cell Biochem 98(5): 1076-1084
50. Bonfield TL, Koloze M, Lennon DP, Zuchowski B, Yang SE, Caplan AI (2010) Human mesenchymal stem cells suppress chronic airway inflammation in the murine ovalbumin asthma model. Am J Physiol Lung Cell Mol Physiol 299:L760-L770
51. Bai L, Lennon DP, Eaton V, Maier K, Caplan AI, Miller SD et al (2009) Human bone marrow- derived mesenchymal stem cells induce th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis. Glia 57:1192-1203
52. Ko IK, Kim B-G et al (2010) Targeting improves MSC treatment of inflammatory bowel disease. Mol Ther 18(7):1365-1372
53. Iyer SS, Rojas M (2008) Anti-inflammatory effects of mesenchymal stem cells: novel concept for future therapies. Expert Opin Biol Ther 8(5):569-581
54. Illingworth CM (1975) Trapped fingers amputated finger tips in children. J Pediatr Surg 9(6):853-858
55. Caplan AI (2010) What's in a name? Tissue Eng Part A 16(8):2415-2417