Effective arterial elastance is insensitive to pulsatile arterial load

Hypertension

Volumn 64, Issue 5, 2014, Pages 1022-1031

  Chirinos, Julio A ^a,b   Rietzschel, Ernst R ^c,d   Shiva Kumar, Prithvi ^b   De Buyzere, Marc L ^c   Zamani, Payman ^a   Claessens, Tom ^d   Geraci, Salvatore ^b   Konda, Prasad ^a   De Bacquer, Dirk ^c   Akers, Scott R ^b   Gillebert, Thierry C ^a   Segers, Patrick ^d  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

Arterial load; Characteristic impedance; Effective arterial elastance; Total arterial compliance; Ventricular arterial coupling; Wave reflections

Indexed keywords

ADULT; AGED; APPLANATION TONOMETER; ARTERIAL PRESSURE; ARTERY BLOOD FLOW; ARTERY COMPLIANCE; ARTICLE; BLOOD PRESSURE METER; BLOOD VESSEL PARAMETERS; FEMALE; HEART AFTERLOAD; HEART CYCLE; HEART HEMODYNAMICS; HEART RATE VARIABILITY; HUMAN; HUMAN EXPERIMENT; ISOMETRIC EXERCISE; MALE; MIDDLE AGED; NORMAL HUMAN; OSCILLOMETER; PRIORITY JOURNAL; PULSATILE ARTERIAL LOAD; PULSE WAVE; SYSTEMIC VASCULAR RESISTANCE; AGING; ARTERIAL STIFFNESS; ARTERY; BLOOD PRESSURE; CARDIOVASCULAR DISEASE; COMPARATIVE STUDY; ELASTICITY; EXERCISE; HEART RATE; MANOMETRY; PATHOPHYSIOLOGY; PHYSIOLOGY; PULSATILE FLOW; VASCULAR RESISTANCE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AGING; ARTERIES; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; ELASTICITY; EXERCISE; FEMALE; HEART RATE; HUMANS; MALE; MANOMETRY; MIDDLE AGED; PULSATILE FLOW; VASCULAR RESISTANCE; VASCULAR STIFFNESS;

EID: 84922394732     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.03696     Document Type: Article

References (47)

1. Nichols W, O'Rourke M, Vlachopolous C. Mcdonald's Blood Flow in Arteries. Theoretical, Experimental and Clinical Principles. London: Hodder Arnold; 2011.
2. Mitchell GF, Tardif JC, Arnold JM, Marchiori G, O'Brien TX, Dunlap ME, Pfeffer MA. Pulsatile hemodynamics in congestive heart failure. Hypertension. 2001;38:1433-1439.
3. Chirinos JA, Kips JG, Jacobs DR Jr, Brumback L, Duprez DA, Kronmal R, Bluemke DA, Townsend RR, Vermeersch S, Segers P. Arterial wave reflections and incident cardiovascular events and heart failure: MESA (Multiethnic Study of Atherosclerosis). J Am Coll Cardiol. 2012;60:2170-2177.
4. Milnor WR. Arterial impedance as ventricular afterload. Circ Res. 1975;36:565-570.
5. Murgo JP, Westerhof N, Giolma JP, Altobelli SA. Aortic input impedance in normal man: relationship to pressure wave forms. Circulation. 1980;62:105-116.
6. Chirinos JA, Segers P. Noninvasive evaluation of left ventricular afterload: part 2: arterial pressure-flow and pressure-volume relations in humans. Hypertension. 2010;56:563-570.
7. O'Rourke MF. Vascular impedance in studies of arterial and cardiac function. Physiol Rev. 1982;62:570-623.
8. Ooi H, Chung W, Biolo A. Arterial stiffness and vascular load in heart failure. Congest Heart Fail. 2008;14:31-36.
9. Chirinos JA, Segers P, Gillebert TC, Gupta AK, De Buyzere ML, De Bacquer D, St John-Sutton M, Rietzschel ER; Asklepios Investigators. Arterial properties as determinants of time-varying myocardial stress in humans. Hypertension. 2012;60:64-70.
10. Coutinho T, Borlaug BA, Pellikka PA, Turner ST, Kullo IJ. Sex differences in arterial stiffness and ventricular-arterial interactions. J Am Coll Cardiol. 2013;61:96-103.
11. Mitchell GF, Lacourcière Y, Ouellet JP, Izzo JL Jr, Neutel J, Kerwin LJ, Block AJ, Pfeffer MA. Determinants of elevated pulse pressure in middleaged and older subjects with uncomplicated systolic hypertension: the role of proximal aortic diameter and the aortic pressure-flow relationship. Circulation. 2003;108:1592-1598.
12. Chirinos JA, Rietzschel ER, De Buyzere ML, De Bacquer D, Gillebert TC, Gupta AK, Segers P; Asklepios Investigators. Arterial load and ventricular-arterial coupling: physiologic relations with body size and effect of obesity. Hypertension. 2009;54:558-566.
13. Sweitzer NK, Shenoy M, Stein JH, Keles S, Palta M, LeCaire T, Mitchell GF. Increases in central aortic impedance precede alterations in arterial stiffness measures in type 1 diabetes. Diabetes Care. 2007;30:2886-2891.
14. Borlaug BA, Melenovsky V, Redfield MM, Kessler K, Chang HJ, Abraham TP, Kass DA. Impact of arterial load and loading sequence on left ventricular tissue velocities in humans. J Am Coll Cardiol. 2007;50:1570-1577.
15. Desai AS, Mitchell GF, Fang JC, Creager MA. Central aortic stiffness is increased in patients with heart failure and preserved ejection fraction. J Card Fail. 2009;15:658-664.
16. Mitchell GF, Dunlap ME, Warnica W, Ducharme A, Arnold JM, Tardif JC, Solomon SD, Domanski MJ, Jablonski KA, Rice MM, Pfeffer MA; Prevention of Events With Angiotensin-Converting Enzyme Inhibition Investigators. Long-term trandolapril treatment is associated with reduced aortic stiffness: the prevention of events with angiotensinconverting enzyme inhibition hemodynamic substudy. Hypertension. 2007;49:1271-1277.
17. Mitchell GF, Lacourcière Y, Arnold JM, Dunlap ME, Conlin PR, Izzo JL Jr. Changes in aortic stiffness and augmentation index after acute converting enzyme or vasopeptidase inhibition. Hypertension. 2005;46:1111-1117.
18. Sunagawa K, Maughan WL, Sagawa K. Optimal arterial resistance for the maximal stroke work studied in isolated canine left ventricle. Circ Res. 1985;56:586-595.
19. Sunagawa K, Maughan WL, Burkhoff D, Sagawa K. Left ventricular interaction with arterial load studied in isolated canine ventricle. Am J Physiol. 1983;245(5 Pt 1):H773-H780.
20. Segers P, Stergiopulos N, Westerhof N. Relation of effective arterial elastance to arterial system properties. Am J Physiol Heart Circ Physiol. 2002;282:H1041-H1046.
21. Chemla D, Antony I, Lecarpentier Y, Nitenberg A. Contribution of systemic vascular resistance and total arterial compliance to effective arterial elastance in humans. Am J Physiol Heart Circ Physiol. 2003;285:H614-H620.
22. Kelly RP, Ting CT, Yang TM, Liu CP, Maughan WL, Chang MS, Kass DA. Effective arterial elastance as index of arterial vascular load in humans. Circulation. 1992;86:513-521.
23. Chirinos JA, Segers P, Raina A, Saif H, Swillens A, Gupta AK, Townsend R, Emmi AG Jr, Kirkpatrick JN, Keane MG, Ferrari VA, Wiegers SE, St John Sutton MG. Arterial pulsatile hemodynamic load induced by isometric exercise strongly predicts left ventricular mass in hypertension. Am J Physiol Heart Circ Physiol. 2010;298:H320-H330.
24. Rietzschel ER, De Buyzere ML, Bekaert S, Segers P, De Bacquer D, Cooman L, Van Damme P, Cassiman P, Langlois M, van Oostveldt P, Verdonck P, De Backer G, Gillebert TC; Asklepios Investigators. Rationale, design, methods and baseline characteristics of the Asklepios Study. Eur J Cardiovasc Prev Rehabil. 2007;14:179-191.
25. Segers P, Rietzschel ER, De Buyzere ML, Vermeersch SJ, De Bacquer D, Van Bortel LM, De Backer G, Gillebert TC, Verdonck PR; Asklepios Investigators. Noninvasive (input) impedance, pulse wave velocity, and wave reflection in healthy middle-aged men and women. Hypertension. 2007;49:1248-1255.
26. Heiberg E, Sjögren J, Ugander M, Carlsson M, Engblom H, Arheden H. Design and validation of Segment-freely available software for cardiovascular image analysis. BMC Med Imaging. 2010;10:1.
27. Chirinos JA, Segers P, Gupta AK, Swillens A, Rietzschel ER, De Buyzere ML, Kirkpatrick JN, Gillebert TC, Wang Y, Keane MG, Townsend R, Ferrari VA, Wiegers SE, St John Sutton M. Time-varying myocardial stress and systolic pressure-stress relationship: role in myocardial-arterial coupling in hypertension. Circulation. 2009;119:2798-2807.
28. Westerhof N, Sipkema P, van den Bos GC, Elzinga G. Forward and backward waves in the arterial system. Cardiovasc Res. 1972;6:648-656.
29. Chirinos JA, Segers P. Noninvasive evaluation of left ventricular afterload: part 1: pressure and flow measurements and basic principles of wave conduction and reflection. Hypertension. 2010;56:555-562.
30. Segers P, Rietzschel ER, De Buyzere ML, De Bacquer D, Van Bortel LM, De Backer G, Gillebert TC, Verdonck PR. Assessment of pressure wave reflection: getting the timing right! Physiol Meas. 2007;28:1045-1056.
31. Stergiopulos N, Meister JJ, Westerhof N. Evaluation of methods for estimation of total arterial compliance. Am J Physiol. 1995;268(4 Pt 2):H1540-H1548.
32. Liu Z, Brin KP, Yin FC. Estimation of total arterial compliance: an improved method and evaluation of current methods. Am J Physiol. 1986;251(3 Pt 2):H588-H600.
33. Mitchell GF. Clinical achievements of impedance analysis. Med Biol Eng Comput. 2009;47:153-163.
34. Weber T, O'Rourke MF, Ammer M, Kvas E, Punzengruber C, Eber B. Arterial stiffness and arterial wave reflections are associated with systolic and diastolic function in patients with normal ejection fraction. Am J Hypertens. 2008;21:1194-1202.
35. Nichols WW, Denardo SJ, Wilkinson IB, McEniery CM, Cockcroft J, O'Rourke MF. Effects of arterial stiffness, pulse wave velocity, and wave reflections on the central aortic pressure waveform. J Clin Hypertens (Greenwich). 2008;10:295-303.
36. Kobayashi S, Yano M, Kohno M, Obayashi M, Hisamatsu Y, Ryoke T, Ohkusa T, Yamakawa K, Matsuzaki M. Influence of aortic impedance on the development of pressure-overload left ventricular hypertrophy in rats. Circulation. 1996;94:3362-3368.
37. Hashimoto J, Westerhof BE, Westerhof N, Imai Y, O'Rourke MF. Different role of wave reflection magnitude and timing on left ventricular mass reduction during antihypertensive treatment. J Hypertens. 2008;26:1017-1024.
38. Westerhof N, O'Rourke MF. Haemodynamic basis for the development of left ventricular failure in systolic hypertension and for its logical therapy. J Hypertens. 1995;13:943-952.
39. Fujimoto N, Onishi K, Tanabe M, Dohi K, Funabiki K, Kurita T, Yamanaka T, Nakajima K, Ito M, Nobori T, Nakano T. Nitroglycerin improves left ventricular relaxation by changing systolic loading sequence in patients with excessive arterial load. J Cardiovasc Pharmacol. 2005;45:211-216.
40. Gillebert TC, Lew WY. Influence of systolic pressure profile on rate of left ventricular pressure fall. Am J Physiol. 1991;261(3 Pt 2):H805-H813.
41. Kohno F, Kumada T, Kambayashi M, Hayashida W, Ishikawa N, Sasayama S. Change in aortic end-systolic pressure by alterations in loading sequence and its relation to left ventricular isovolumic relaxation. Circulation. 1996;93:2080-2087.
42. Hori M, Inoue M, Kitakaze M, Kitabatake A, Abe H. Altered loading sequence as an underlying mechanism of afterload dependency of ventricular relaxation in hearts in situ. Jpn Circ J. 1985;49:245-254.
43. Chen CH, Fetics B, Nevo E, Rochitte CE, Chiou KR, Ding PA, Kawaguchi M, Kass DA. Noninvasive single-beat determination of left ventricular end-systolic elastance in humans. J Am Coll Cardiol. 2001;38: 2028-2034.
44. Weber T, Wassertheurer S, O'Rourke MF, Haiden A, Zweiker R, Rammer M, Hametner B, Eber B. Pulsatile hemodynamics in patients with exertional dyspnea: potentially of value in the diagnostic evaluation of suspected heart failure with preserved ejection fraction. J Am Coll Cardiol. 2013;61:1874-1883.
45. Burke MA, Katz DH, Beussink L, Selvaraj S, Gupta DK, Fox J, Chakrabarti S, Sauer AJ, Rich JD, Freed BH, Shah SJ. Prognostic importance of pathophysiologic markers in patients with heart failure and preserved ejection fraction. Circ Heart Fail. 2014;7:288-299.
46. Fukuta H, Ohte N, Wakami K, Asada K, Goto T, Mukai S, Tani T, Kimura G. Impact of arterial load on left ventricular diastolic function in patients undergoing cardiac catheterization for coronary artery disease. Circ J. 2010;74:1900-1905.
47. Chirinos JA, Segers P, Rietzschel ER, De Buyzere ML, Raja MW, Claessens T, De Bacquer D, St John Sutton M, Gillebert TC; Asklepios Investigators. Early and late systolic wall stress differentially relate to myocardial contraction and relaxation in middle-aged adults: the Asklepios study. Hypertension. 2013;61:296-303.