Long-term trandolapril treatment is associated with reduced aortic stiffness: The prevention of events with angiotensin-converting enzyme inhibition hemodynamic substudy

Hypertension

Volumn 49, Issue 6, 2007, Pages 1271-1277

  Mitchell, Gary F ^a   Dunlap, Mark E ^b   Warnica, Wayne ^c   Ducharme, Anique ^d   Arnold, J Malcolm O ^e   Tardif, Jean Claude ^d   Solomon, Scott D ^f   Domanski, Michael J ^g   Jablonski, Kathleen A ^h   Rice, Madeline M ^h   Pfeffer, Marc A ^f  

^a CARDIOVASCULAR ENGINEERING INC   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^c FOOTHILLS HOSPITAL   (Canada)

^d MONTREAL HEART INSTITUTE   (Canada)

^e LONDON HEALTH SCIENCES CENTRE   (Canada)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^h GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Angiotensin converting enzyme; Arterial stiffness; Coronary artery disease; Pulse wave velocity; Randomized clinical trial

Indexed keywords

ACETYLSALICYLIC ACID; ANTILIPEMIC AGENT; ANTITHROMBOCYTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PLACEBO; TRANDOLAPRIL;

ADULT; AGED; ANALYTICAL PARAMETERS; AORTA; AORTA WALL; ARTERY COMPLIANCE; ARTERY TONE; ARTICLE; BODY MASS; BODY SURFACE; BRACHIAL ARTERY; CAROTID ARTERY; CHEMOPROPHYLAXIS; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DRUG DOSE INCREASE; DRUG EFFECT; ECHOCARDIOGRAPHY; FEMALE; FEMORAL ARTERY; FOLLOW UP; GEOMETRY; GROUPS BY AGE; HEART EJECTION FRACTION; HEMODYNAMICS; HUMAN; IMPEDANCE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; PREVENTIVE MEDICINE; PRIORITY JOURNAL; PULSATILE FLOW; PULSE PRESSURE; PULSE WAVE; RANDOMIZATION; STATISTICAL SIGNIFICANCE; TONOMETRY; TREATMENT DURATION; TREATMENT OUTCOME;

AGED; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIHYPERTENSIVE AGENTS; AORTA; ATHEROSCLEROSIS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; CAROTID ARTERIES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELASTICITY; FEMORAL ARTERY; HUMANS; HYPERTENSION; INDOLES; LONGITUDINAL STUDIES; MIDDLE AGED; PULSATILE FLOW; REGIONAL BLOOD FLOW;

EID: 34249336754     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.106.085738     Document Type: Article

References (41)

1. Mattace-Raso FU, van der Cammen TJ, Hofman A, van Popele NM, Bos ML, Schalekamp MA, Asmar R, Reneman RS, Hoeks AP, Breteler MM, Witteman JC. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation. 2006;113:657-663.
2. Sutton-Tyrrell K, Najjar SS, Boudreau RM, Venkitachalam L, Kupelian V, Simonsick EM, Havlik R, Lakatta EG, Spurgeon H, Kritchevsky S, Pahor M, Bauer D, Newman A. Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation. 2005;111:3384-3390.
3. Willum-Hansen T, Staessen JA, Torp-Pedersen C, Rasmussen S, Thijs L, Ibsen H, Jeppesen J. Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population. Circulation. 2006;113:664-670.
4. Domanski MJ, Davis BR, Pfeffer MA, Kastantin M, Mitchell GF. Isolated systolic hypertension: prognostic information provided by pulse pressure. Hypertension. 1999;34:375-380.
5. Mitchell GF, Moye LA, Braunwald E, Rouleau JL, Bernstein V, Geltman EM, Flaker GC, Pfeffer MA. Sphygmomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function. SAVE investigators. Survival and Ventricular Enlargement. Circulation. 1997;96:4254-4260.
6. Mitchell GF, Vita JA, Larson MG, Parise H, Keyes MJ, Warner E, Vasan RS, Levy D, Benjamin EJ. Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study. Circulation. 2005;112:3722-3728.
7. Benetos A, Topouchian J, Ricard S, Gautier S, Bonnardeaux A, Asmar R, Poirier O, Soubrier F, Safar M, Cambien F. Influence of angiotensin II type 1 receptor polymorphism on aortic stiffness in never-treated hypertensive patients. Hypertension. 1995;26:44-47.
8. Ting CT, Chen CH, Chang MS, Yin FC. Short- and long-term effects of antihypertensive drugs on arterial reflections, compliance, and impedance. Hypertension. 1995;26:524-530.
9. Topouchian J, Brisac AM, Pannier B, Vicaut E, Safar M, Asmar R. Assessment of the acute arterial effects of converting enzyme inhibition in essential hypertension: a double-blind, comparative and crossover study. J Hum Hypertens. 1998;12:181-187.
10. Topouchian J, Asmar R, Sayegh F, Rudnicki A, Benetos A, Bacri AM, Safar ME. Changes in arterial structure and function under trandolaprilverapamil combination in hypertension. Stroke. 1999;30:1056-1064.
11. Asmar RG, London GM, O'Rourke ME, Safar ME. Improvement in blood pressure, arterial stiffness and wave reflections with a verylow-dose perindopril/indapamide combination in hypertensive patient: a comparison with atenolol. Hypertension. 2001;38:922-926.
12. Mitchell GF, Izzo JL Jr, Lacourciere Y, Ouellet JP, Neutel J, Qian C, Kerwin LJ, Block AJ, Pfeffer MA. Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension: results of the conduit hemodynamics of omapatrilat international research study. Circulation. 2002;105:2955-2961.
13. Mahmud A, Feely J. Reduction in arterial stiffness with angiotensin II antagonist is comparable with and additive to ACE inhibition. Am J Hypertens. 2002;15:321-325.
14. Lacourciere Y, Beliveau R, Conter HS, Burgess ED, Lepage S, Pesant Y, Spence JD, Asmar R, Carriere S, Plante GE. Effects of perindopril on elastic and structural properties of large arteries in essential hypertension. Can J Cardiol. 2004;20:795-799.
15. Mitchell GF, Arnold JM, Dunlap ME, O'Brien TX, Marchiori G, Warner E, Granger CB, Desai SS, Pfeffer MA. Pulsatile hemodynamic effects of candesartan in patients with chronic heart failure: the CHARM Program. Eur J Heart Fail. 2006;8:191-197.
16. Rutherford JD, Pfeffer MA, Moye LA, Davis BR, Flaker GC, Kowey PR, Lamas GA, Miller HS, Packer M, Rouleau JL. Effects of captopril on ischemic events after myocardial infarction. Results of the Survival and Ventricular Enlargement trial. SAVE Investigators. Circulation. 1994;90:1731-1738.
17. Yusuf S, Pepine CJ, Garces C, Pouleur H, Salem D, Kostis J, Benedict C, Rousseau M, Bourassa M, Pitt B. Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions. Lancet. 1992;340:1173-1178.
18. The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions The SOLVD Investigators. N Engl J Med. 1992;327:685-691.
19. Braunwald E, Domanski MJ, Fowler SE, Geller NL, Gersh BJ, Hsia J, Pfeffer MA, Rice MM, Rosenberg YD, Rouleau JL. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med. 2004;351:2058-2068.
20. Pfeffer MA, Domanski M, Rosenberg Y, Verter J, Geller N, Albert P, Hsia J, Braunwald E . Prevention of events with angiotensin-converting enzyme inhibition (the PEACE study design). Prevention of Events with Angiotensin-Converting Enzyme Inhibition. Am J Cardiol. 1998;82:25H-30H.
21. Kelly R, Fitchett D. Noninvasive determination of aortic input impedance and external left ventricular power output: a validation and repeatability study of a new technique. J Am Coll Cardiol. 1992;20:952-963.
22. Mitchell GF, Tardif JC, Arnold JM, Marchiori G, O'Brien TX, Dunlap ME, Pfeffer MA. Pulsatile hemodynamics in congestive heart failure. Hypertension. 2001;38:1433-1439.
23. Liu Z, Brin KP, Yin FC. Estimation of total arterial compliance: an improved method and evaluation of current methods. Am J Physiol. 1986;251:H588-H600.
24. Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994;74:1141-1148.
25. Morishita R, Gibbons GH, Ellison KE, Lee W, Zhang L, Yu H, Kaneda Y, Ogihara T, Dzau VJ. Evidence for direct local effect of angiotensin in vascular hypertrophy In vivo gene transfer of angiotensin converting enzyme. J Clin Invest. 1994;94:978-984.
26. Kinlay S, Creager MA, Fukumoto M, Hikita H, Fang JC, Selwyn AP, Ganz P. Endothelium-derived nitric oxide regulates arterial elasticity in human arteries in vivo. Hypertension. 2001;38:1049-1053.
27. Ramsey MW, Goodfellow J, Jones CJ, Luddington LA, Lewis MJ, Henderson AH. Endothelial control of arterial distensibility is impaired in chronic heart failure. Circulation. 1995;92:3212-3219.
28. Balkestein EJ, Staessen JA, Wang JG, van der Heijden-Spek JJ, Van Bortel LM, Barlassina C, Bianchi G, Brand E, Herrmann SM, Struijker-Boudier HA. Carotid and femoral artery stiffness in relation to three candidate genes in a white population. Hypertension. 2001;38:1190-1197.
29. Benetos A, Gautier S, Ricard S, Topouchian J, Asmar R, Poirier O, Larosa E, Guize L, Safar M, Soubrier F, Cambien F. Influence of angiotensin-converting enzyme and angiotensin II type 1 receptor gene polymorphisms on aortic stiffness in normotensive and hypertensive patients. Circulation. 1996;94:698-703.
30. Hosoi M, Nishizawa Y, Kogawa K, Kawagishi T, Konishi T, Maekawa K, Emoto M, Fukumoto S, Shioi A, Shoji T, Inaba M, Okuno Y, Morii H. Angiotensin- converting enzyme gene polymorphism is associated with carotid arterial wall thickness in non-insulin-dependent diabetic patients. Circulation. 1996;94:704-707.
31. Mattace-Raso FU, van der Cammen TJ, Sayed-Tabatabaei FA, van Popele NM, Asmar R, Schalekamp MA, Hofman A, van Duijn CM, Witteman JC. Angiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam study. Atherosclerosis. 2004;174:121-126.
32. Safar ME, Cattan V, Lacolley P, Nzietchueng R, Labat C, Lajemi M, De Luca N, Benetos A. Aldosterone synthase gene polymorphism, stroke volume and age-related changes in aortic pulse wave velocity in subjects with hypertension. J Hypertens. 2005;23:1159-1166.
33. Safar ME, Lajemi M, Rudnichi A, Asmar R, Benetos A. Angiotensin- converting enzyme D/I gene polymorphism and age-related changes in pulse pressure in subjects with hypertension. Arterioscler Thromb Vasc Biol. 2004;24:782-786.
34. Ahimastos AA, Natoli AK, Lawler A, Blombery PA, Kingwell BA. Ramipril reduces large-artery stiffness in peripheral arterial disease and promotes elastogenic remodeling in cell culture. Hypertension. 2005;45:1194-1199.
35. Mitchell GF, Lacourciere Y, Ouellet JP, Izzo JL Jr, Neutel J, Kerwin LJ, Block AJ, Pfeffer MA. Determinants of elevated pulse pressure in middle-aged and older subjects with uncomplicated systolic hypertension: the role of proximal aortic diameter and the aortic pressure-flow relationship. Circulation. 2003;108:1592-1598.
36. Mitchell GF, Parise H, Benjamin EJ, Larson MG, Keyes MJ, Vita JA, Vasan RS, Levy D. Changes in arterial stiffness and wave reflection with advancing age in healthy men and women: the Framingham Heart Study. Hypertension. 2004;43:1239-1245.
37. Ting CT, Yang TM, Chen JW, Chang MS, Yin FC. Arterial hemodynamics in human hypertension. Effects of angiotensin converting enzyme inhibition. Hypertension. 1993;22:839-846.
38. Mitchell GF, Lacourciere Y, Arnold JM, Dunlap ME, Conlin PR, Izzo JL Jr. Changes in aortic stiffness and augmentation index after acute converting enzyme or vasopeptidase inhibition. Hypertension. 2005;46:1111-1117.
39. Safar ME, Van Bortel LM, Struijker-Boudier HA. Resistance and conduit arteries following converting enzyme inhibition in hypertension. J Vasc Res. 1997;34:67-81.
40. Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, Ducimetiere P, Benetos A. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension. 2001;37:1236-1241.
41. Meaume S, Benetos A, Henry OF, Rudnichi A, Safar ME. Aortic pulse wave velocity predicts cardiovascular mortality in subjects >70 years of age. Arterioscler Thromb Vasc Biol. 2001;21:2046-2050.