메뉴 건너뛰기




Volumn 35, Issue 8, 2014, Pages 7441-7449

Prognostic factors in oral and oropharyngeal cancer based on ultrastructural analysis and DNA methylation of the tumor and surgical margin

Author keywords

Methylation; Oral cancer; Prognostic factors; Ultrastructural examination

Indexed keywords

ACID ANHYDRIDE HYDROLASE; FRAGILE HISTIDINE TRIAD PROTEIN; TUMOR PROTEIN;

EID: 84922393422     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1007/s13277-014-1958-1     Document Type: Article
Times cited : (8)

References (56)
  • 1
    • 67349186933 scopus 로고    scopus 로고
    • Global epidemiology of oral and oropharyngeal cancer
    • PID: 18804401
    • Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol. 2009;45(4–5):309–16.
    • (2009) Oral Oncol , vol.45 , Issue.4-5 , pp. 309-316
    • Warnakulasuriya, S.1
  • 2
    • 71649109232 scopus 로고    scopus 로고
    • Causes of oral cancer—an appraisal of controversies
    • COI: 1:STN:280:DC%2BD1MjovFaquw%3D%3D, PID: 19946320
    • Warnakulasuriya S. Causes of oral cancer—an appraisal of controversies. Br Dent J. 2009;207(10):471–5.
    • (2009) Br Dent J , vol.207 , Issue.10 , pp. 471-475
    • Warnakulasuriya, S.1
  • 3
    • 77956168003 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the oral tongue in patients younger than 30 years: clinicopathologic features and outcome
    • COI: 1:STN:280:DC%2BC3cjnsVOmtQ%3D%3D, PID: 20738340
    • Soudry E, Preis M, Hod R, Hamzany Y, Hadar T, et al. Squamous cell carcinoma of the oral tongue in patients younger than 30 years: clinicopathologic features and outcome. Clin Otolaryngol. 2010;35(4):307–12.
    • (2010) Clin Otolaryngol , vol.35 , Issue.4 , pp. 307-312
    • Soudry, E.1    Preis, M.2    Hod, R.3    Hamzany, Y.4    Hadar, T.5
  • 4
    • 67650376394 scopus 로고    scopus 로고
    • Recent changes in the epidemiology of head and neck cancer
    • PID: 19363341
    • Curado MP, Hashibe M. Recent changes in the epidemiology of head and neck cancer. Curr Opin Oncol. 2009;21(3):194–200.
    • (2009) Curr Opin Oncol , vol.21 , Issue.3 , pp. 194-200
    • Curado, M.P.1    Hashibe, M.2
  • 5
    • 34347370856 scopus 로고    scopus 로고
    • Clinical and histopathological analysis of squamous cell carcinoma of the head and neck in young adults
    • PID: 17605411
    • Gawecki W, Szyfter K, Szyfter W. Clinical and histopathological analysis of squamous cell carcinoma of the head and neck in young adults. Otolaryngol Pol. 2007;61(1):11–6.
    • (2007) Otolaryngol Pol , vol.61 , Issue.1 , pp. 11-16
    • Gawecki, W.1    Szyfter, K.2    Szyfter, W.3
  • 6
    • 36148957500 scopus 로고    scopus 로고
    • The role of genetic factor in etiopathogenesis of squamous cell carcinoma of the head and neck in young adults
    • PID: 17653748
    • Gawecki W, Kostrzewska-Poczekaj M, Gajecka M, Milecki P, Szyfter K, et al. The role of genetic factor in etiopathogenesis of squamous cell carcinoma of the head and neck in young adults. Eur Arch Otorhinolaryngol. 2007;264(12):1459–65.
    • (2007) Eur Arch Otorhinolaryngol , vol.264 , Issue.12 , pp. 1459-1465
    • Gawecki, W.1    Kostrzewska-Poczekaj, M.2    Gajecka, M.3    Milecki, P.4    Szyfter, K.5
  • 7
    • 79955849251 scopus 로고    scopus 로고
    • Retrospective analysis of the treatment failure of the oral cancer in Department of Otolaryngology and Clinical Oncology University of Medical Sciences in Poznan in the year 2000–2005
    • PID: 21574494
    • Mielcarek-Kuchta D, Wierzbicka M, Mietkiewska D, Kopec T, Banaszewski J, et al. Retrospective analysis of the treatment failure of the oral cancer in Department of Otolaryngology and Clinical Oncology University of Medical Sciences in Poznan in the year 2000–2005. Otolaryngol Pol. 2011;65(1):26–32.
    • (2011) Otolaryngol Pol , vol.65 , Issue.1 , pp. 26-32
    • Mielcarek-Kuchta, D.1    Wierzbicka, M.2    Mietkiewska, D.3    Kopec, T.4    Banaszewski, J.5
  • 8
    • 60749090160 scopus 로고    scopus 로고
    • Human papillomavirus and cancer of the oropharynx. Molecular interaction and clinical implications
    • COI: 1:STN:280:DC%2BD1M7kvF2qtg%3D%3D, PID: 19194683
    • Klussmann JP, Preuss SF, Speel EJ. Human papillomavirus and cancer of the oropharynx. Molecular interaction and clinical implications. HNO. 2009;57(2):113–22.
    • (2009) HNO , vol.57 , Issue.2 , pp. 113-122
    • Klussmann, J.P.1    Preuss, S.F.2    Speel, E.J.3
  • 9
    • 63449130280 scopus 로고    scopus 로고
    • Genetic signatures of HPV-related and unrelated oropharyngeal carcinoma and their prognostic implications
    • COI: 1:CAS:528:DC%2BD1MXisVWrsL4%3D, PID: 19223504
    • Klussmann JP, Mooren JJ, Lehnen M, Claessen SM, Stenner M, et al. Genetic signatures of HPV-related and unrelated oropharyngeal carcinoma and their prognostic implications. Clin Cancer Res. 2009;15(5):1779–86.
    • (2009) Clin Cancer Res , vol.15 , Issue.5 , pp. 1779-1786
    • Klussmann, J.P.1    Mooren, J.J.2    Lehnen, M.3    Claessen, S.M.4    Stenner, M.5
  • 10
    • 43049097865 scopus 로고    scopus 로고
    • Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas
    • COI: 1:CAS:528:DC%2BD1cXht1eku73I, PID: 18360824
    • Hafkamp HC, Manni JJ, Haesevoets A, Voogd AC, Schepers M, et al. Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas. Int J Cancer. 2008;122(12):2656–64.
    • (2008) Int J Cancer , vol.122 , Issue.12 , pp. 2656-2664
    • Hafkamp, H.C.1    Manni, J.J.2    Haesevoets, A.3    Voogd, A.C.4    Schepers, M.5
  • 11
    • 34548680936 scopus 로고    scopus 로고
    • Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: review and meta-analysis
    • COI: 1:CAS:528:DC%2BD2sXhtVyktb7E, PID: 17546592
    • Ragin CC, Taioli E. Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: review and meta-analysis. Int J Cancer. 2007;121(8):1813–20.
    • (2007) Int J Cancer , vol.121 , Issue.8 , pp. 1813-1820
    • Ragin, C.C.1    Taioli, E.2
  • 12
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin
    • COI: 1:STN:280:DyaG2c%2FhsFCntw%3D%3D, PID: 13094644
    • Slaughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer. 1953;6(5):963–8.
    • (1953) Cancer , vol.6 , Issue.5 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 13
    • 9344247476 scopus 로고    scopus 로고
    • Genetic progression model for head and neck cancer: implications for field cancerization
    • COI: 1:CAS:528:DyaK28XjtlCgtLo%3D, PID: 8653682
    • Califano J, van der Riet P, Westra W, Nawroz H, Clayman G, et al. Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res. 1996;56(11):2488–92.
    • (1996) Cancer Res , vol.56 , Issue.11 , pp. 2488-2492
    • Califano, J.1    van der Riet, P.2    Westra, W.3    Nawroz, H.4    Clayman, G.5
  • 14
    • 0037446974 scopus 로고    scopus 로고
    • A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications
    • COI: 1:CAS:528:DC%2BD3sXivFygu7k%3D, PID: 12702551
    • Braakhuis BJ, Tabor MP, Kummer JA, Leemans CR, Brakenhoff RH. A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications. Cancer Res. 2003;63(8):1727–30.
    • (2003) Cancer Res , vol.63 , Issue.8 , pp. 1727-1730
    • Braakhuis, B.J.1    Tabor, M.P.2    Kummer, J.A.3    Leemans, C.R.4    Brakenhoff, R.H.5
  • 15
    • 0036333198 scopus 로고    scopus 로고
    • Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention
    • COI: 1:CAS:528:DC%2BD38XlvVenu74%3D, PID: 12147432
    • Hecht SS. Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention. Lancet Oncol. 2002;3(8):461–9.
    • (2002) Lancet Oncol , vol.3 , Issue.8 , pp. 461-469
    • Hecht, S.S.1
  • 16
    • 0037152633 scopus 로고    scopus 로고
    • DNA adduct burden and tobacco carcinogenesis
    • COI: 1:CAS:528:DC%2BD38XnvVelurg%3D, PID: 12379880
    • Wiencke JK. DNA adduct burden and tobacco carcinogenesis. Oncogene. 2002;21(48):7376–91.
    • (2002) Oncogene , vol.21 , Issue.48 , pp. 7376-7391
    • Wiencke, J.K.1
  • 17
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: the DNA hypermethylome
    • COI: 1:CAS:528:DC%2BD2sXosFOht7Y%3D, PID: 17613547
    • Esteller M. Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum Mol Genet. 2007;16(1):R50–9.
    • (2007) Hum Mol Genet , vol.16 , Issue.1 , pp. R50-R59
    • Esteller, M.1
  • 18
    • 29744431723 scopus 로고    scopus 로고
    • Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma
    • COI: 1:CAS:528:DC%2BD28XksFOk, PID: 16389187
    • Ha PK, Califano JA. Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma. Lancet Oncol. 2006;7(1):77–82.
    • (2006) Lancet Oncol , vol.7 , Issue.1 , pp. 77-82
    • Ha, P.K.1    Califano, J.A.2
  • 19
    • 79952384705 scopus 로고    scopus 로고
    • Cancer epigenetics reaches mainstream oncology
    • COI: 1:CAS:528:DC%2BC3MXivVGgtb8%3D, PID: 21386836
    • Rodriguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat Med. 2011;17(3):330–9.
    • (2011) Nat Med , vol.17 , Issue.3 , pp. 330-339
    • Rodriguez-Paredes, M.1    Esteller, M.2
  • 20
    • 70350345008 scopus 로고    scopus 로고
    • Significance of promoter hypermethylation of p16 gene for margin assessment in carcinoma tongue
    • PID: 19431196
    • Sinha P, Bahadur S, Thakar A, Matta A, Macha M, et al. Significance of promoter hypermethylation of p16 gene for margin assessment in carcinoma tongue. Head Neck. 2009;31(11):1423–30.
    • (2009) Head Neck , vol.31 , Issue.11 , pp. 1423-1430
    • Sinha, P.1    Bahadur, S.2    Thakar, A.3    Matta, A.4    Macha, M.5
  • 21
    • 35748966123 scopus 로고    scopus 로고
    • Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma
    • PID: 17559992
    • Shaw RJ, Hall GL, Woolgar JA, Lowe D, Rogers SN, et al. Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma. Br J Oral Maxillofac Surg. 2007;45(8):617–22.
    • (2007) Br J Oral Maxillofac Surg , vol.45 , Issue.8 , pp. 617-622
    • Shaw, R.J.1    Hall, G.L.2    Woolgar, J.A.3    Lowe, D.4    Rogers, S.N.5
  • 22
    • 0037080420 scopus 로고    scopus 로고
    • Loss of E-cadherin expression resulting from promoter hypermethylation in oral tongue carcinoma and its prognostic significance
    • COI: 1:CAS:528:DC%2BD38XhtV2qsrk%3D, PID: 11900224
    • Chang HW, Chow V, Lam KY, Wei WI, Yuen A. Loss of E-cadherin expression resulting from promoter hypermethylation in oral tongue carcinoma and its prognostic significance. Cancer. 2002;94(2):386–92.
    • (2002) Cancer , vol.94 , Issue.2 , pp. 386-392
    • Chang, H.W.1    Chow, V.2    Lam, K.Y.3    Wei, W.I.4    Yuen, A.5
  • 23
    • 1642568676 scopus 로고    scopus 로고
    • Ataxia-telangiectasia-mutated (ATM) gene in head and neck squamous cell carcinoma: promoter hypermethylation with clinical correlation in 100 cases
    • COI: 1:CAS:528:DC%2BD2cXmsVWiuw%3D%3D, PID: 14744748
    • Ai L, Vo QN, Zuo C, Li L, Ling W, et al. Ataxia-telangiectasia-mutated (ATM) gene in head and neck squamous cell carcinoma: promoter hypermethylation with clinical correlation in 100 cases. Cancer Epidemiol Biomarkers Prev. 2004;13(1):150–6.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , Issue.1 , pp. 150-156
    • Ai, L.1    Vo, Q.N.2    Zuo, C.3    Li, L.4    Ling, W.5
  • 24
    • 0037102370 scopus 로고    scopus 로고
    • Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine
    • COI: 1:CAS:528:DC%2BD38XmsVShsbs%3D, PID: 12183435
    • McGregor F, Muntoni A, Fleming J, Brown J, Felix DH, et al. Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine. Cancer Res. 2002;62(16):4757–66.
    • (2002) Cancer Res , vol.62 , Issue.16 , pp. 4757-4766
    • McGregor, F.1    Muntoni, A.2    Fleming, J.3    Brown, J.4    Felix, D.H.5
  • 25
    • 35648953334 scopus 로고    scopus 로고
    • Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma
    • COI: 1:CAS:528:DC%2BD2sXhtlertbrF, PID: 17876837
    • Hsu HS, Chen TP, Hung CH, Wen CK, Lin RK, et al. Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma. Cancer. 2007;110(9):2019–26.
    • (2007) Cancer , vol.110 , Issue.9 , pp. 2019-2026
    • Hsu, H.S.1    Chen, T.P.2    Hung, C.H.3    Wen, C.K.4    Lin, R.K.5
  • 26
    • 0037103190 scopus 로고    scopus 로고
    • ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma
    • COI: 1:CAS:528:DC%2BD38Xmt12iurg%3D, PID: 12149228
    • Gronbaek K, Worm J, Ralfkiaer E, Ahrenkiel V, Hokland P, et al. ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma. Blood. 2002;100(4):1430–7.
    • (2002) Blood , vol.100 , Issue.4 , pp. 1430-1437
    • Gronbaek, K.1    Worm, J.2    Ralfkiaer, E.3    Ahrenkiel, V.4    Hokland, P.5
  • 27
    • 39749140314 scopus 로고    scopus 로고
    • Modulation of gene methylation by genistein or lycopene in breast cancer cells
    • COI: 1:CAS:528:DC%2BD1cXhtlWhs7c%3D, PID: 18181168
    • King-Batoon A, Leszczynska JM, Klein CB. Modulation of gene methylation by genistein or lycopene in breast cancer cells. Environ Mol Mutagen. 2008;49(1):36–45.
    • (2008) Environ Mol Mutagen , vol.49 , Issue.1 , pp. 36-45
    • King-Batoon, A.1    Leszczynska, J.M.2    Klein, C.B.3
  • 29
    • 4644228483 scopus 로고    scopus 로고
    • Promoter hypermethylation and protein expression of the p16 gene: analysis of 43 cases of B-cell primary gastric lymphomas from China
    • COI: 1:CAS:528:DC%2BD2cXmsVOitrk%3D, PID: 14976529
    • Huang Q. A.L., Zhang ZY, Fan CY, Weiss LM., Promoter hypermethylation and protein expression of the p16 gene: analysis of 43 cases of B-cell primary gastric lymphomas from China. Mod Pathol. 2004;17(4):416–22.
    • (2004) Mod Pathol , vol.17 , Issue.4 , pp. 416-422
    • Huang, Q.1
  • 30
    • 1842856019 scopus 로고    scopus 로고
    • Molecular footprints of human lung cancer progression
    • COI: 1:CAS:528:DC%2BD2cXjs1ymur0%3D, PID: 15016317
    • Yokota J, Kohno T. Molecular footprints of human lung cancer progression. Cancer Sci. 2004;95(3):197–204.
    • (2004) Cancer Sci , vol.95 , Issue.3 , pp. 197-204
    • Yokota, J.1    Kohno, T.2
  • 31
    • 0027979126 scopus 로고
    • Ultrastructure of oral squamous cell carcinoma: a comparative analysis of different histological types
    • COI: 1:STN:280:DyaK2s3otFKlsQ%3D%3D, PID: 9135971
    • Kannan S, Kartha CC, Chandran GJ, Pillai MR, Sudha L, et al. Ultrastructure of oral squamous cell carcinoma: a comparative analysis of different histological types. Eur J Cancer B Oral Oncol. 1994;30B(1):32–42.
    • (1994) Eur J Cancer B Oral Oncol , vol.30B , Issue.1 , pp. 32-42
    • Kannan, S.1    Kartha, C.C.2    Chandran, G.J.3    Pillai, M.R.4    Sudha, L.5
  • 32
    • 0036019910 scopus 로고    scopus 로고
    • Ultrastructural changes in malignant transformation of oral mucosa
    • PID: 12054710
    • Cheng LH, Hudson J. Ultrastructural changes in malignant transformation of oral mucosa. Br J Oral Maxillofac Surg. 2002;40(3):207–12.
    • (2002) Br J Oral Maxillofac Surg , vol.40 , Issue.3 , pp. 207-212
    • Cheng, L.H.1    Hudson, J.2
  • 33
    • 0030024649 scopus 로고    scopus 로고
    • Ultrastructural analysis of the adjacent epithelium of oral squamous cell carcinoma
    • COI: 1:STN:280:DyaK283jtV2nsw%3D%3D, PID: 8645684
    • Kannan S, Kartha CC, Balaram P, Chandran GJ, Pillai MR, et al. Ultrastructural analysis of the adjacent epithelium of oral squamous cell carcinoma. Br J Oral Maxillofac Surg. 1996;34(1):51–7.
    • (1996) Br J Oral Maxillofac Surg , vol.34 , Issue.1 , pp. 51-57
    • Kannan, S.1    Kartha, C.C.2    Balaram, P.3    Chandran, G.J.4    Pillai, M.R.5
  • 34
    • 78049255727 scopus 로고    scopus 로고
    • Impact of different surgical margin conditions on local recurrence of oral squamous cell carcinoma
    • PID: 20920879
    • Kurita H, Nakanishi Y, Nishizawa R, Xiao T, Kamata T, et al. Impact of different surgical margin conditions on local recurrence of oral squamous cell carcinoma. Oral Oncol. 2010;46(11):814–7.
    • (2010) Oral Oncol , vol.46 , Issue.11 , pp. 814-817
    • Kurita, H.1    Nakanishi, Y.2    Nishizawa, R.3    Xiao, T.4    Kamata, T.5
  • 35
    • 0032856620 scopus 로고    scopus 로고
    • Pattern of invasion and margin assessment in patients with oral tongue cancer
    • COI: 1:STN:280:DyaK1Mzjt1arsg%3D%3D, PID: 10402520
    • Spiro RH, Guillamondegui Jr O, Paulino AF, Huvos AG. Pattern of invasion and margin assessment in patients with oral tongue cancer. Head Neck. 1999;21(5):408–13.
    • (1999) Head Neck , vol.21 , Issue.5 , pp. 408-413
    • Spiro, R.H.1    Guillamondegui, O.2    Paulino, A.F.3    Huvos, A.G.4
  • 36
    • 0141504062 scopus 로고    scopus 로고
    • Influence of condition of surgical margins on local recurrence and disease-specific survival in oral and oropharyngeal cancer
    • COI: 1:STN:280:DC%2BD3svgslOgtA%3D%3D, PID: 12946663
    • McMahon J, O'Brien CJ, Pathak I, Hamill R, McNeil E, et al. Influence of condition of surgical margins on local recurrence and disease-specific survival in oral and oropharyngeal cancer. Br J Oral Maxillofac Surg. 2003;41(4):224–31.
    • (2003) Br J Oral Maxillofac Surg , vol.41 , Issue.4 , pp. 224-231
    • McMahon, J.1    O'Brien, C.J.2    Pathak, I.3    Hamill, R.4    McNeil, E.5
  • 37
    • 33947122744 scopus 로고    scopus 로고
    • The uncertainty of the surgical margin in the treatment of head and neck cancer
    • COI: 1:STN:280:DC%2BD2s3ktFyksQ%3D%3D, PID: 17112772
    • Upile T, Fisher C, Jerjes W, El Maaytah M, Searle A, et al. The uncertainty of the surgical margin in the treatment of head and neck cancer. Oral Oncol. 2007;43(4):321–6.
    • (2007) Oral Oncol , vol.43 , Issue.4 , pp. 321-326
    • Upile, T.1    Fisher, C.2    Jerjes, W.3    El Maaytah, M.4    Searle, A.5
  • 38
    • 34547860042 scopus 로고    scopus 로고
    • The clinical significance of the positive surgical margin in oral cancer
    • PID: 17174145
    • Binahmed A, Nason RW, Abdoh AA. The clinical significance of the positive surgical margin in oral cancer. Oral Oncol. 2007;43(8):780–4.
    • (2007) Oral Oncol , vol.43 , Issue.8 , pp. 780-784
    • Binahmed, A.1    Nason, R.W.2    Abdoh, A.A.3
  • 39
    • 32644475906 scopus 로고    scopus 로고
    • Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma
    • PID: 16150633
    • Woolgar JA. Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma. Oral Oncol. 2006;42(3):229–39.
    • (2006) Oral Oncol , vol.42 , Issue.3 , pp. 229-239
    • Woolgar, J.A.1
  • 40
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • COI: 1:CAS:528:DC%2BD2sXivVGktbk%3D, PID: 17339880
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet. 2007;8(4):286–98.
    • (2007) Nat Rev Genet , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 41
    • 26644462391 scopus 로고    scopus 로고
    • Cancer epigenetics is no Mickey Mouse
    • COI: 1:CAS:528:DC%2BD2MXhtFOrtLrI, PID: 16226700
    • Feinberg AP. Cancer epigenetics is no Mickey Mouse. Cancer Cell. 2005;8(4):267–8.
    • (2005) Cancer Cell , vol.8 , Issue.4 , pp. 267-268
    • Feinberg, A.P.1
  • 42
    • 84878618073 scopus 로고    scopus 로고
    • Protein expression and promoter methylation of the candidate biomarker TCF21 in head and neck squamous cell carcinoma
    • COI: 1:CAS:528:DC%2BC3sXnvFyitb4%3D
    • Weiss D, Stockmann C, Schrodter K, Rudack C. Protein expression and promoter methylation of the candidate biomarker TCF21 in head and neck squamous cell carcinoma. Cell Oncol (Dordr). 2013;36(3):213–24.
    • (2013) Cell Oncol (Dordr) , vol.36 , Issue.3 , pp. 213-224
    • Weiss, D.1    Stockmann, C.2    Schrodter, K.3    Rudack, C.4
  • 43
    • 84865343917 scopus 로고    scopus 로고
    • Aberrant DNA methylation of tumor-related genes in oral rinse: a noninvasive method for detection of oral squamous cell carcinoma
    • COI: 1:CAS:528:DC%2BC38Xht1Wrsb3P, PID: 22252571
    • Nagata S, Hamada T, Yamada N, Yokoyama S, Kitamoto S, et al. Aberrant DNA methylation of tumor-related genes in oral rinse: a noninvasive method for detection of oral squamous cell carcinoma. Cancer. 2012;118(17):4298–308.
    • (2012) Cancer , vol.118 , Issue.17 , pp. 4298-4308
    • Nagata, S.1    Hamada, T.2    Yamada, N.3    Yokoyama, S.4    Kitamoto, S.5
  • 44
    • 84863424417 scopus 로고    scopus 로고
    • The correlations between alteration of p16 gene and clinicopathological factors and prognosis in squamous cell carcinomas of the buccal mucosa
    • PID: 22429295
    • Dong Y, Wang J, Dong F, Wang X, Zhang Y. The correlations between alteration of p16 gene and clinicopathological factors and prognosis in squamous cell carcinomas of the buccal mucosa. J Oral Pathol Med. 2012;41(6):463–9.
    • (2012) J Oral Pathol Med , vol.41 , Issue.6 , pp. 463-469
    • Dong, Y.1    Wang, J.2    Dong, F.3    Wang, X.4    Zhang, Y.5
  • 45
    • 84877095575 scopus 로고    scopus 로고
    • Clinical correlates of promoter hypermethylation of four target genes in head and neck cancer: a cooperative group correlative study
    • COI: 1:CAS:528:DC%2BC3sXntVWqs7o%3D, PID: 23444219
    • Roh JL, Wang XV, Manola J, Sidransky D, Forastiere AA, et al. Clinical correlates of promoter hypermethylation of four target genes in head and neck cancer: a cooperative group correlative study. Clin Cancer Res. 2013;19(9):2528–40.
    • (2013) Clin Cancer Res , vol.19 , Issue.9 , pp. 2528-2540
    • Roh, J.L.1    Wang, X.V.2    Manola, J.3    Sidransky, D.4    Forastiere, A.A.5
  • 46
    • 85027945506 scopus 로고    scopus 로고
    • Promoter hypermethylation in primary squamous cell carcinoma of the oral cavity and oropharynx: a study of a Brazilian cohort
    • COI: 1:CAS:528:DC%2BC38Xhs1SqsL3M, PID: 22936053
    • de Freitas Cordeiro-Silva M. E. Stur, L.P. Agostini, J.R. de Podesta, J.C. de Oliveira, et al., Promoter hypermethylation in primary squamous cell carcinoma of the oral cavity and oropharynx: a study of a Brazilian cohort. Mol Biol Rep. 2012;39(12):10111–9.
    • (2012) Mol Biol Rep , vol.39 , Issue.12 , pp. 10111-10119
    • de Freitas Cordeiro-Silva, M.1
  • 47
    • 33344455657 scopus 로고    scopus 로고
    • Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing
    • COI: 1:CAS:528:DC%2BD28Xhs1ers7s%3D, PID: 16449996
    • Shaw RJ, Liloglou T, Rogers SN, Brown JS, Vaughan ED, et al. Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing. Br J Cancer. 2006;94(4):561–8.
    • (2006) Br J Cancer , vol.94 , Issue.4 , pp. 561-568
    • Shaw, R.J.1    Liloglou, T.2    Rogers, S.N.3    Brown, J.S.4    Vaughan, E.D.5
  • 48
    • 84859300811 scopus 로고    scopus 로고
    • P16 gene methylation in colorectal cancer patients with long-term follow-up
    • COI: 1:CAS:528:DC%2BC38XmvFaqtLc%3D, PID: 22449151
    • Veganzones-de-Castro S, Rafael-Fernandez S, Vidaurreta-Lazaro M. V. de-la-Orden, B. Mediero-Valeros, et al., p16 gene methylation in colorectal cancer patients with long-term follow-up. Rev Esp Enferm Dig. 2012;104(3):111–7.
    • (2012) Rev Esp Enferm Dig , vol.104 , Issue.3 , pp. 111-117
    • Veganzones-de-Castro, S.1    Rafael-Fernandez, S.2    Vidaurreta-Lazaro, M.3
  • 49
    • 0032145266 scopus 로고    scopus 로고
    • Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas
    • COI: 1:CAS:528:DyaK1cXltFyis7o%3D, PID: 9699676
    • Tanaka H, Shimada Y, Harada H, Shinoda M, Hatooka S, et al. Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas. Cancer Res. 1998;58(15):3429–34.
    • (1998) Cancer Res , vol.58 , Issue.15 , pp. 3429-3434
    • Tanaka, H.1    Shimada, Y.2    Harada, H.3    Shinoda, M.4    Hatooka, S.5
  • 50
    • 79551689151 scopus 로고    scopus 로고
    • Frequent hypermethylation of DAPK, RARbeta, MGMT, RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa
    • COI: 1:CAS:528:DC%2BC3MXhslOjs7k%3D, PID: 21147548
    • Paluszczak J, Misiak P, Wierzbicka M, Wozniak A, Baer-Dubowska W. Frequent hypermethylation of DAPK, RARbeta, MGMT, RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa. Oral Oncol. 2011;47(2):104–7.
    • (2011) Oral Oncol , vol.47 , Issue.2 , pp. 104-107
    • Paluszczak, J.1    Misiak, P.2    Wierzbicka, M.3    Wozniak, A.4    Baer-Dubowska, W.5
  • 51
    • 78650524204 scopus 로고    scopus 로고
    • Frequent gene hypermethylation in laryngeal cancer cell lines and the resistance to demethylation induction by plant polyphenols
    • COI: 1:CAS:528:DC%2BC3cXhs1agsLnF, PID: 21078381
    • Paluszczak J, Krajka-Kuzniak V, Malecka Z, Jarmuz M, Kostrzewska-Poczekaj M, et al. Frequent gene hypermethylation in laryngeal cancer cell lines and the resistance to demethylation induction by plant polyphenols. Toxicol In Vitro. 2011;25(1):213–21.
    • (2011) Toxicol In Vitro , vol.25 , Issue.1 , pp. 213-221
    • Paluszczak, J.1    Krajka-Kuzniak, V.2    Malecka, Z.3    Jarmuz, M.4    Kostrzewska-Poczekaj, M.5
  • 52
    • 49649112722 scopus 로고    scopus 로고
    • ATM in oral carcinogenesis: association with clinicopathological features
    • COI: 1:CAS:528:DC%2BD1cXps12msLc%3D, PID: 18288488
    • He Y, Chen Q, Li B. ATM in oral carcinogenesis: association with clinicopathological features. J Cancer Res Clin Oncol. 2008;134(9):1013–20.
    • (2008) J Cancer Res Clin Oncol , vol.134 , Issue.9 , pp. 1013-1020
    • He, Y.1    Chen, Q.2    Li, B.3
  • 53
    • 84880270465 scopus 로고    scopus 로고
    • Molecular staging of surgical margins in oral squamous cell carcinoma using promoter methylation of p16(INK4A), cytoglobin, E-cadherin, and TMEFF2
    • PID: 23111707
    • Shaw RJ, Hobkirk AJ, Nikolaidis G, Woolgar JA, Triantafyllou A, et al. Molecular staging of surgical margins in oral squamous cell carcinoma using promoter methylation of p16(INK4A), cytoglobin, E-cadherin, and TMEFF2. Ann Surg Oncol. 2013;20(8):2796–802.
    • (2013) Ann Surg Oncol , vol.20 , Issue.8 , pp. 2796-2802
    • Shaw, R.J.1    Hobkirk, A.J.2    Nikolaidis, G.3    Woolgar, J.A.4    Triantafyllou, A.5
  • 54
    • 34247130418 scopus 로고    scopus 로고
    • Status of primary tumour surgical margins in squamous head and neck cancer: prognostic implications
    • PID: 17413406
    • Bradley PJ, MacLennan K, Brakenhoff RH, Leemans CR. Status of primary tumour surgical margins in squamous head and neck cancer: prognostic implications. Curr Opin Otolaryngol Head Neck Surg. 2007;15(2):74–81.
    • (2007) Curr Opin Otolaryngol Head Neck Surg , vol.15 , Issue.2 , pp. 74-81
    • Bradley, P.J.1    MacLennan, K.2    Brakenhoff, R.H.3    Leemans, C.R.4
  • 55
    • 27644585239 scopus 로고    scopus 로고
    • New molecular diagnostic methods in head and neck cancer
    • PID: 16200629
    • Rodrigo JP, Ferlito A, Suarez C, Shaha AR, Silver CE, et al. New molecular diagnostic methods in head and neck cancer. Head Neck. 2005;27(11):995–1003.
    • (2005) Head Neck , vol.27 , Issue.11 , pp. 995-1003
    • Rodrigo, J.P.1    Ferlito, A.2    Suarez, C.3    Shaha, A.R.4    Silver, C.E.5
  • 56
    • 77953361281 scopus 로고    scopus 로고
    • Molecular analysis of surgical margins in head and neck cancer: more than a marginal issue
    • COI: 1:CAS:528:DC%2BC3cXnvVejsr8%3D, PID: 20189442
    • Braakhuis BJ, Bloemena E, Leemans CR, Brakenhoff RH. Molecular analysis of surgical margins in head and neck cancer: more than a marginal issue. Oral Oncol. 2010;46(7):485–91.
    • (2010) Oral Oncol , vol.46 , Issue.7 , pp. 485-491
    • Braakhuis, B.J.1    Bloemena, E.2    Leemans, C.R.3    Brakenhoff, R.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.