ncRuPAR inhibits gastric cancer progression by down-regulating protease-activated receptor-1

Tumor Biology

Volumn 35, Issue 8, 2014, Pages 7821-7829

  Liu, Long ^a   Yan, Bing ^b   Yang, Zhihui ^c   Zhang, Xiaodong ^d   Gu, Qunhao ^d   Yue, Xiaoqiang ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c The 81st Hospital of PLA   (China)

^d SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Gastric carcinoma; Long noncoding RNA; ncRuPAR; Protease activated receptor 1

Indexed keywords

LONG UNTRANSLATED RNA; PROTEINASE ACTIVATED RECEPTOR 1; VASCULOTROPIN A;

ADULT; AGED; ANTAGONISTS AND INHIBITORS; DISEASE COURSE; FEMALE; GENETICS; HUMAN; MALE; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; RECEIVER OPERATING CHARACTERISTIC; STOMACH TUMOR;

ADULT; AGED; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; RECEPTOR, PAR-1; RNA, LONG NONCODING; ROC CURVE; STOMACH NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84922392061     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1007/s13277-014-2042-6     Document Type: Article

References (35)

1. Brenner H, Rothenbacher D, Arndt V. Epidemiology of stomach cancer. Methods Mol Biol. 2009;472:467–77.
2. Zhu Y, Xiao X, Dong L, et al. Investigation and identification of let-7a related functional proteins in gastric carcinoma by proteomics. Anal Cell Pathol (Amst). 2012;35(4):285–95.
3. Zhai XF, Chen Z, Li B, et al. Traditional herbal medicine in preventing recurrence after resection of small hepatocellular carcinoma: a multicenter randomized controlled trial. J Integr Med. 2013;11:90–100.
4. Sun DZ, Liu L, Jiao JP, et al. Syndrome characteristics of traditional Chinese medicine: summary of a clinical survey in 767 patients with gastric cancer. J Chinese Integr Med. 2010;8(4):332–40.
5. Wang WJ. Enhancing the treatment of metabolic syndrome with integrative medicine. J Integr Med. 2013;11(3):153–6.
6. Liu D, Zhang Z, Kong CZ. High FOXM1 expression was associated with bladder carcinogenesis. Tumor Biol. 2013;34:1131–8.
7. Hu BS, Hu H, Zhu CY, et al. Overexpression of GOLPH3 is associated with poor clinical outcome in gastric cancer. Tumor Biol. 2013;34(1):515–20.
8. Yang F, Bi JW, Xue XC, et al. Upregulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells. FEBS J. 2012;279(17):3159–65.
9. Ponting CP, Oliver PL, Reik W. Evolution and functions of long noncoding RNAs. Cell. 2009;136(4):629–41.
10. Muers M. RNA: genome-wide views of long non-coding RNAs. Nat Rev Genet. 2011;12(11):742.
11. Huarte M, Guttman M, Feldser D, et al. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 2010;142(3):409–19.
12. Gupta RA, Shah N, Wang KC, et al. Long noncoding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 2010;464(7291):1071–6.
13. Panzitt K, Tschernatsch MM, Guelly C, et al. Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA. Gastroenterology. 2007;132(1):330–42.
14. Wang KC, Chang HY. Molecular mechanisms of long noncoding RNAs. Mol Cell. 2011;43(6):904–14.
15. Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: new links in cancer progression. Cancer Res. 2011;71(1):3–7.
16. Yan B, Wang Z. Long noncoding RNA. Its physiological and pathological roles. DNA Cell Biol. 2012;31 Suppl 1:S34–41.
17. Madamanchi NR, Hu ZY, Li F, et al. A noncoding RNA regulates human protease-activated receptor-1 gene during embryogenesis. Biochim Biophys Acta. 2002;1576(3):237–45.
18. Trotti A, Fritz AG, Compton CC, et al. AJCC cancer staging manual. 7th ed. New York: Springer; 2009. p. 117–26.
19. Sarela AI, Verbeke CS, Ramsdale J, et al. Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. Br J Cancer. 2002;86:886–92.
20. Barbareschi M, Maisonneuve P, Aldovini D, et al. High syndecan-1 expression in breast carcinoma is related to an aggressive phenotype and to poorer prognosis. Cancer. 2003;98(3):474–83.
21. Lee SR, Kim HO, Shin JH, et al. Prognostic significance of quantitative carcinoembryonic antigen and cytokeratin 20 mRNA detection in peritoneal washes of gastric cancer patients. Hepatogastroenterology. 2013;60(125):1237–44.
22. Yoshimizu T, Miroglio A, Ripoche MA, et al. The H19 locus acts in vivo as a tumor suppressor. Proc Natl Acad Sci U S A. 2008;105(34):12417–22.
23. Matouk IJ, DeGroot N, Mezan S, et al. The H19 non-coding RNA is essential for human tumor growth. PLoS One. 2007;2(9):e845.
24. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature. 2000;407(6801):249–57.
25. Folkman J. Tumor angiogenic therapeutic implications. N Engl J Med. 1971;285(21):1182–6.
26. Coughlin SR. Thrombin signalling and protease-activated receptors. Nature. 2000;407(6801):258–64.
27. Dorsam RT, Gutkind JS. G-protein-coupled receptors and cancer. Nat Rev Cancer. 2007;7(2):79–94.
28. Even-Ram S, Uziely B, Cohen P, et al. Thrombin receptor overexpression in malignant and physiological invasion processes. Nat Med. 1998;4(8):909–14.
29. Darmoul D, Gratio V, Devaud H, et al. Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells. Am J Pathol. 2003;162(5):1503–13.
30. Daaka Y. G proteins in cancer: the prostate cancer paradigm. Sci STKE. 2004;2004(216):re2.
31. Vu TK, Hung DT, Wheaton VI, et al. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 1991;64(6):1057–68.
32. Yin YJ, Salah Z, Maoz M, et al. Oncogenic transformation induces tumor angiogenesis: a role for PAR1 activation. FASEB J. 2003;17(2):163–74.
33. Mei DY, Song HJ, Wang K, et al. Up-regulation of SUMO1 pseudogene 3 (SUMO1P3) in gastric cancer and its clinical association. Med Oncol. 2013;30(4):709.
34. Mohammadreza H, Mehrdad B, Majid S, et al. Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues. Med Oncol. 2013;30(3):670.
35. Sun WL, Wu YB, Yu X, et al. Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance. Tumor Biol. 2013;34(5):2697–701.