NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

Journal of Investigative Dermatology

Volumn 134, Issue 10, 2014, Pages 2630-2638

  South, Andrew P ^a   Purdie, Karin J ^b   Watt, Stephen A ^a   Haldenby, Sam ^c   Den Breems, Nicoline Y ^a   Dimon, Michelle ^d   Arron, Sarah T ^d   Kluk, Michael J ^e   Aster, Jon C ^e   McHugh, Angela ^a   Xue, Dylan J ^a   Dayal, Jasbani H S ^a   Robinson, Kim S ^a   Rizvi, S M Hasan ^f   Proby, Charlotte M ^a   Harwood, Catherine A ^b   Leigh, Irene M ^a,b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f BARTS HEALTH NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINASE; B RAF KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA POLYMERASE; ENRASENTAN; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; PROTEIN P53; VEMURAFENIB; HRAS PROTEIN, HUMAN; INDOLE DERIVATIVE; NOTCH RECEPTOR; NOTCH1 PROTEIN, HUMAN; PROTEIN P21; SULFONAMIDE;

AMPLICON; ARTICLE; CARCINOGENESIS; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA REPLICATION TIMING; EXCISION REPAIR; EXOME; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; MICROSATELLITE INSTABILITY; MISSENSE MUTATION; MUTATION RATE; NONSENSE MUTATION; ONCOGENE RAS; OPEN READING FRAME; PRIORITY JOURNAL; PYROSEQUENCING; RECEPTOR DOWN REGULATION; SOMATIC MUTATION; SQUAMOUS CELL; SQUAMOUS CELL CARCINOMA; AGED; ANTAGONISTS AND INHIBITORS; BIOPSY; CASE CONTROL STUDY; DOWN REGULATION; FEMALE; GENETICS; MALE; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SKIN; SKIN DISEASES; SKIN TUMOR; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BIOPSY; CARCINOGENESIS; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; DOWN-REGULATION; FEMALE; HUMANS; INDOLES; MALE; MIDDLE AGED; MUTATION; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); RECEPTOR, NOTCH1; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; SKIN; SKIN DISEASES; SKIN NEOPLASMS; SULFONAMIDES;

EID: 84922391333     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.154     Document Type: Article

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