Mechanism of allosteric inhibition of HIV-1 reverse transcriptase revealed by single-molecule and ensemble fluorescence

Nucleic Acids Research

Volumn 42, Issue 18, 2014, Pages 11687-11696

  Schauer, Grant D ^a,c   Huber, Kelly D ^b   Leuba, Sanford H ^a   Sluis Cremer, Nicolas ^b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOXAZINE DERIVATIVE; DEOXYRIBONUCLEOTIDE; EFAVIRENZ; PRIMER DNA; PROTEIN SUBUNIT; REVERSE TRANSCRIPTASE, HUMAN IMMUNODEFICIENCY VIRUS 1; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ALLOSTERISM; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DNA TEMPLATE; FLUORESCENCE POLARIZATION; GENETICS; METABOLISM; MUTATION; PROTEIN SUBUNIT;

ALLOSTERIC REGULATION; BENZOXAZINES; DEOXYRIBONUCLEOTIDES; DNA PRIMERS; FLUORESCENCE POLARIZATION; HIV REVERSE TRANSCRIPTASE; MUTATION; PROTEIN SUBUNITS; REVERSE TRANSCRIPTASE INHIBITORS; TEMPLATES, GENETIC;

EID: 84922372074     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku819     Document Type: Article

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