Naphthoquinone derivative PPE8 induces endoplasmic reticulum stress in p53 Null H1299 cells

Oxidative Medicine and Cellular Longevity

Volumn 2015, Issue , 2015, Pages

  Lien, Jin Cherng ^a   Huang, Chien Chun ^b   Lu, Te Jung ^c   Tseng, Chih Hsiang ^a   Sung, Ping Jyun ^d,e   Lee, Hong Zin ^a   Bao, Bo Ying ^a   Kuo, Yueh Hsiung ^a,f   Lu, Te Ling ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b ASIA UNIVERSITY   (Taiwan)

^c CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^d NATIONAL DONG HWA UNIVERSITY   (Taiwan)

^e NATIONAL MUSEUM OF MARINE BIOLOGY AND AQUARIUM   (Taiwan)

^f ASIA UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELL DEATH; CELL MEMBRANES; CYTOLOGY; CYTOTOXICITY; ENZYMES; KETONES; OXYGEN; PHOSPHORYLATION; PROTEINS;

APOPTOSIS SIGNAL REGULATING KINASE 1; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC CELLS; NAPHTHOQUINONES; PHARMACOLOGICAL AGENTS; PHENOLIC COMPOUNDS; TRANS-MEMBRANE PROTEINS;

CELLS;

1,4 NAPHTHOQUINONE DERIVATIVE; APOPTOSIS SIGNAL REGULATING KINASE 1; GLUCOSE REGULATED PROTEIN 78; MENADIONE; PPE8 NAPHTHOQUINONE DERIVATIVE; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 3-CHLORO-2-(N,N-DIMETHYLAMINOETHYLAMINO)-1,4-NAPHTHOQUINONE; ERN1 PROTEIN, HUMAN; ETHYLENEDIAMINE DERIVATIVE; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; NAPHTHOQUINONE; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; SMALL INTERFERING RNA;

A549 CELL LINE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL LINE; CANCER INHIBITION; CELL DEATH; CELL FUNCTION; DRUG SYNTHESIS; ENDOPLASMIC RETICULUM STRESS; ENZYME PHOSPHORYLATION; EUKARYOTIC CELL; H1299 CELL LINE; NULL CELL; OXIDATION; OXYGEN CONSUMPTION; PROTEIN FOLDING; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE; SYNTHESIS; TUMOR CELL LINE;

EUKARYOTA;

CELL LINE, TUMOR; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; ETHYLENEDIAMINES; HEAT-SHOCK PROTEINS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NAPHTHOQUINONES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84922361006     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2015/453679     Document Type: Article

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