ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis

Autophagy

Volumn 10, Issue 12, 2014, Pages 2223-2238

  Xiong, Yuyan ^a   Yepuri, Gautham ^a,b   Forbiteh, Michael ^a   Yu, Yi ^a   Montani, Jean Pierre ^a   Yang, Zhihong ^a   Ming, Xiu Fen ^a  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

Author keywords

ARGINASE; Atherosclerosis; Autophagy; Endothelial cells; MTOR; PRKAA; Senescence

Indexed keywords

ARGINASE; ARGINASE 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; UNCLASSIFIED DRUG; ARG2 PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MTOR PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

AORTA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; AUTOPHAGY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYPERARGININEMIA; HYPERLIPOPROTEINEMIA TYPE 3; LIPID DIET; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; CELL AGING; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALIA; MUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ARGINASE; ATHEROSCLEROSIS; AUTOPHAGY; CELL AGING; DIET, HIGH-FAT; HUMANS; MICE, TRANSGENIC; MULTIPROTEIN COMPLEXES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84922355342     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/15548627.2014.981789     Document Type: Article

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