Mitochondrial alarmins released by degenerating motor axon terminals activate perisynaptic schwann cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 5, 2015, Pages E497-E505

  Duregotti, Elisa ^a   Negro, Samuele ^a   Scorzeto, Michele ^a   Zornetta, Irene ^a   Dickinson, Bryan C ^b,d   Chang, Christopher J ^b   Montecucco, Cesare ^a,c   Rigoni, Michela ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CNR   (Italy)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

Mitochondrial alarmins; Motor axon degeneration; Presynaptic neurotoxins; Schwann cells

Indexed keywords

CALCIUM; CYTOCHROME C; HYDROGEN PEROXIDE; MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCULTURE; CONTROLLED STUDY; DEGENERATIVE DISEASE; IN VIVO STUDY; INTRACELLULAR SIGNALING; MITOCHONDRIAL ALARMIN; MITOCHONDRION; MOLECULE; MOTOR NEURON DISEASE; MOUSE; NERVE CELL; NERVE ENDING; NEUROMUSCULAR SYNAPSE; NONHUMAN; PERISYNAPTIC SCHWANN CELL; PRIORITY JOURNAL; SCHWANN CELL; ANIMAL; METABOLISM; NERVE FIBER; PHAGOCYTOSIS; SNAKE; SPIDER; SYNAPSE;

ANIMALIA; ARANEAE;

ANIMALS; AXONS; COCULTURE TECHNIQUES; CYTOCHROMES C; DNA, MITOCHONDRIAL; MITOCHONDRIA; NEUROTOXINS; PHAGOCYTOSIS; SCHWANN CELLS; SNAKES; SPIDERS; SYNAPSES;

EID: 84922311781     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1417108112     Document Type: Article

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