Astragaloside IV controls collagen reduction in photoaging skin by improving transforming growth factor-β/Smad signaling suppression and inhibiting matrix metalloproteinase-1

Molecular Medicine Reports

Volumn 11, Issue 5, 2015, Pages 3344-3348

  Chen, Bin ^a   Li, Ran ^a   Yan, Ning ^a   Chen, Gang ^a   Qian, Wen ^a   Jiang, Hui Li ^a   Ji, Chao ^b   Bi, Zhi Gang ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Astragaloside IV; Matrix metalloproteinase; Photoaging; Transforming growth factor Smad signaling; Type I procollagen

Indexed keywords

ASTRAGALOSIDE IV; INTERSTITIAL COLLAGENASE; PROCOLLAGEN; PROCOLLAGEN TYPE 1; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG; ASTRAGALOSIDE A; COLLAGEN; PROTEIN SERINE THREONINE KINASE; SAPONIN; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR; TRITERPENE;

ARTICLE; CELL VIABILITY; COLLAGEN DEGRADATION; CONTROLLED STUDY; CUTANEOUS PARAMETERS; DOWN REGULATION; DRUG EFFECT; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MTT ASSAY; PHOTOAGING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; WESTERN BLOTTING; ADVERSE EFFECTS; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RADIATION RESPONSE; ULTRAVIOLET RADIATION;

ASTRAGALUS MEMBRANACEUS;

CELL LINE; CELL SURVIVAL; COLLAGEN; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MATRIX METALLOPROTEINASE 1; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SAPONINS; SIGNAL TRANSDUCTION; SKIN AGING; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TRITERPENES; ULTRAVIOLET RAYS;

EID: 84922311481     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3212     Document Type: Article

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