Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 5, 2015, Pages E410-E419

  Walmacq, Celine ^a   Wang, Lanfeng ^b   Chong, Jenny ^b   Scibelli, Kathleen ^a   Lubkowska, Lucyna ^a   Gnatt, Averell ^c   Brooks, Philip J ^d,e   Wang, Dong ^b   Kashlev, Mikhail ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c Biopolcore   (United States)

^d NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Oxidative DNA damage; RNA polymerase II; Transcription factor TFIIF; Transcriptional mutagenesis; Translesion transcription

Indexed keywords

8,5' CYCLO 2' DEOXYADENOSINE; ADENOSINE PHOSPHATE; DEOXYADENOSINE DERIVATIVE; PYRIMIDINE DIMER; RNA POLYMERASE II; UNCLASSIFIED DRUG; DNA; PURINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA TEMPLATE; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; MUTAGENESIS; OXIDATIVE STRESS; PRIORITY JOURNAL; SYNTHESIS; TRANSCRIPTION INITIATION; X RAY CRYSTALLOGRAPHY; CHEMISTRY; GENETIC TRANSCRIPTION; METABOLISM; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION;

BASE SEQUENCE; DNA; DNA DAMAGE; OXIDATION-REDUCTION; PURINES; RNA POLYMERASE II; TRANSCRIPTION, GENETIC;

EID: 84922309452     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1415186112     Document Type: Article

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