Signaling networks in palate development

Wiley Interdisciplinary Reviews: Systems Biology and Medicine

Volumn 6, Issue 3, 2014, Pages 271-278

  Lane, Jamie ^a   Kaartinen, Vesa ^a  

^a UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KERATINOCYTE GROWTH FACTOR; SONIC HEDGEHOG PROTEIN;

ARTICLE; BIOLOGY; CELL DIFFERENTIATION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM; GENE EXPRESSION; GENE FUNCTION; GENETICS; HUMAN; NONHUMAN; ORGANOGENESIS; PALATE; SIGNAL TRANSDUCTION; ANIMAL; EMBRYO DEVELOPMENT; EPITHELIUM CELL; GROWTH, DEVELOPMENT AND AGING; MESENCHYMAL STROMA CELL; METABOLISM;

ANIMALS; EMBRYONIC DEVELOPMENT; EPITHELIAL CELLS; HUMANS; MESENCHYMAL STROMAL CELLS; PALATE; SIGNAL TRANSDUCTION;

EID: 84922275175     PISSN: 19395094     EISSN: 1939005X     Source Type: Journal    
DOI: 10.1002/wsbm.1265     Document Type: Article

References (57)

1. Murray JC. Gene/environment causes of cleft lip and/or palate. Clin Genet 2002, 61:248-256.
2. Schutte BC, Murray JC. The many faces and factors of orofacial clefts. Hum Mol Genet 1999, 8:1853-1859.
3. Dixon MJ, Marazita ML, Beaty TH, Murray JC. Cleft lip and palate: understanding genetic and environmental influences. Nat Rev Genet 2011, 12:167-178.
4. Bush JO, Jiang R. Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development. Development 2012, 139:231-243.
5. Gritli-Linde A. Molecular control of secondary palate development. Dev Biol 2007, 301:309-326.
6. Pelikan RC, Iwata J, Suzuki A, Chai Y, Hacia JG. Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling. J Cell Biochem 2013, 114:796-807.
7. Seelan RS, Mukhopadhyay P, Pisano MM, Greene RM. Developmental epigenetics of the murine secondary palate. ILAR J 2012, 53:240-252.
8. Meng L, Bian Z, Torensma R. Von den Hoff JW. Biological mechanisms in palatogenesis and cleft palate. J Dent Res 2009, 88:22-33.
9. Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP. Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest 2004, 113:1692-1700.
10. Lan Y, Jiang R. Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth. Development 2009, 136:1387-1396.
11. Economou AD, Ohazama A, Porntaveetus T, Sharpe PT, Kondo S, Basson MA, Gritli-Linde A, Cobourne MT, Green JB. Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate. Nat Genet 2012, 44:348-351.
12. Baek JA, Lan Y, Liu H, Maltby KM, Mishina Y, Jiang R. Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Dev Biol 2011, 350:520-531.
13. Hilliard SA, Yu L, Gu S, Zhang Z, Chen YP. Regional regulation of palatal growth and patterning along the anterior-posterior axis in mice. J Anat 2005, 207:655-667.
14. Li L, Lin M, Wang Y, Cserjesi P, Chen Z, Chen Y. BmprIa is required in mesenchymal tissue and has limited redundant function with BmprIb in tooth and palate development. Dev Biol 2011, 349:451-461.
15. Zhang Z, Song Y, Zhao X, Zhang X, Fermin C, Chen Y. Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis. Development 2002, 129:4135-4146.
16. Zhou J, Gao Y, Lan Y, Jia S, Jiang R. Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis. Development 2013, 140:4709-4718.
17. Han J, Mayo J, Xu X, Li J, Bringas P Jr, Maas RL, Rubenstein JL, Chai Y. Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice. Development 2009, 136:4225-4233.
18. Lan Y, Ovitt CE, Cho ES, Maltby KM, Wang Q, Jiang R. Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development 2004, 131:3207-3216.
19. Zhang L, Yoshimura Y, Hatta T, Otani H. Myogenic determination and differentiation of the mouse palatal muscle in relation to the developing mandibular nerve. J Dent Res 1999, 78:1417-1425.
20. Rot-Nikcevic I, Reddy T, Downing KJ, Belliveau AC, Hallgrimsson B, Hall BK, Kablar B. Myf5-/- : MyoD-/- amyogenic fetuses reveal the importance of early contraction and static loading by striated muscle in mouse skeletogenesis. Dev Genes Evol 2006, 216:1-9.
21. Li Q, Ding J. Gene expression analysis reveals that formation of the mouse anterior secondary palate involves recruitment of cells from the posterior side. Int J Dev Biol 2007, 51:167-172.
22. Liu W, Lan Y, Pauws E, Meester-Smoor MA, Stanier P, Zwarthoff EC, Jiang R. The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice. Development 2008, 135:3959-3968.
23. Bush JO, Lan Y, Maltby KM, Jiang R. Isolation and developmental expression analysis of Tbx22, the mouse homolog of the human X-linked cleft palate gene. Dev Dyn 2002, 225:322-326.
24. Pauws E, Hoshino A, Bentley L, Prajapati S, Keller C, Hammond P, Martinez-Barbera JP, Moore GE, Stanier P. Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes. Hum Mol Genet 2009, 18:4171-4179.
25. Ferguson MW. Palate development: mechanisms and malformations. Ir J Med Sci 1987, 156:309-315.
26. Walker BD, Fraser FC. Closure of the secondary palate in three strains of mice. J Embryol Exp Morphol 1956, 4:176-189.
27. Yu K, Ornitz DM. Histomorphological study of palatal shelf elevation during murine secondary palate formation. Dev Dyn 2011, 240:1737-1744.
28. Ferguson MW. Palate development. Development 1988, 103(Suppl):41-60.
29. Ingraham CR, Kinoshita A, Kondo S, Yang B, Sajan S, Trout KJ, Malik MI, Dunnwald M, Goudy SL, Lovett M, et al. Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6). Nat Genet 2006, 38:1335-1340.
30. Richardson RJ, Dixon J, Jiang R, Dixon MJ. Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence. Hum Mol Genet 2009, 18:2632-2642.
31. Vaziri Sani F, Hallberg K, Harfe BD, McMahon AP, Linde A, Gritli-Linde A. Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Dev Biol 2005, 285:490-495.
32. Yoshida M, Shimono Y, Togashi H, Matsuzaki K, Miyoshi J, Mizoguchi A, Komori T, Takai Y. Periderm cells covering palatal shelves have tight junctions and their desquamation reduces the polarity of palatal shelf epithelial cells in palatogenesis. Genes Cells 2012, 17:455-472.
33. Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H. Tbx1 regulates oral epithelial adhesion and palatal development. Hum Mol Genet 2012, 21:2524-2537.
34. Humphreys R, Zheng W, Prince LS, Qu X, Brown C, Loomes K, Huppert SS, Baldwin S, Goudy S. Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients. Hum Mol Genet 2012, 21:1374-1383.
35. Casey LM, Lan Y, Cho ES, Maltby KM, Gridley T, Jiang R. Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development. Dev Dyn 2006, 235:1830-1844.
36. Dudas M, Li WY, Kim J, Yang A, Kaartinen V. Palatal fusion - Where do the midline cells go? A review on cleft palate, a major human birth defect. Acta Histochem 2007, 109:1-14.
37. Xu X, Han J, Ito Y, Bringas P Jr, Urata MM, Chai Y. Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusion. Dev Biol 2006, 297:238-248.
38. Pelton RW, Dickinson ME, Moses HL, Hogan BL. In situ hybridization analysis of TGF β3 RNA expression during mouse development: comparative studies with TGF β1 and β2. Development 1990, 110:609-620.
39. Millan FA, Denhez F, Kondaiah P, Akhurst RJ. Embryonic gene expression patterns of TGF β1, β2 and β3 suggest different developmental functions in vivo. Development 1991, 111:131-143.
40. Proetzel G, Pawlowski SA, Wiles MV, Yin M, Boivin GP, Howles PN, Ding J, Ferguson MW, Doetschman T. Transforming growth factor-β3 is required for secondary palate fusion. Nat Genet 1995, 11:409-414.
41. Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J. Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction. Nat Genet 1995, 11:415-421.
42. Dudas M, Kim J, Li WY, Nagy A, Larsson J, Karlsson S, Chai Y, Kaartinen V. Epithelial and ectomesenchymal role of the type I TGF-β receptor ALK5 during facial morphogenesis and palatal fusion. Dev Biol 2006, 296:298-314.
43. He F, Xiong W, Wang Y, Li L, Liu C, Yamagami T, Taketo MM, Zhou C, Chen Y. Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression. Dev Biol 2011, 350:511-519.
44. Venza I, Visalli M, Parrillo L, De Felice M, Teti D, Venza M. MSX1 and TGF-β3 are novel target genes functionally regulated by FOXE1. Hum Mol Genet 2011, 20:1016-1025.
45. Xu X, Han J, Ito Y, Bringas P Jr, Deng C, Chai Y. Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-β/BMP signaling during tooth and palate development. Dev Cell 2008, 15:322-329.
46. Iwata J, Suzuki A, Pelikan RC, Ho TV, Sanchez-Lara PA, Urata M, Dixon MJ, Chai Y. Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. Development 2013, 140:1220-1230.
47. Emmert-Streib F, Glazko GV. Network biology: a direct approach to study biological function. Wiley Interdiscip Rev Syst Biol Med 2011, 3:379-391.
48. Bensimon A, Heck AJ, Aebersold R. Mass spectrometry-based proteomics and network biology. Annu Rev Biochem 2012, 81:379-405.
49. Ito Y, Yeo JY, Chytil A, Han J, Bringas P Jr, Nakajima A, Shuler CF, Moses HL, Chai Y. Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. Development 2003, 130:5269-5280.
50. Chai Y, Jiang X, Ito Y, Bringas P Jr, Han J, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development 2000, 127:1671-1679.
51. Iwata J, Hacia JG, Suzuki A, Sanchez-Lara PA, Urata M, Chai Y. Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice. J Clin Invest 2012, 122:873-885.
52. Iwata J, Suzuki A, Pelikan RC, Ho TV, Sanchez-Lara PA, Chai Y. Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice. Hum Mol Genet 2013, 23:182-193.
53. Ozturk F, Li Y, Zhu X, Guda C, Nawshad A. Systematic analysis of palatal transcriptome to identify cleft palate genes within TGFβ3-knockout mice alleles: RNA-Seq analysis of TGFβ3 Mice. BMC Genomics 2013, 14:113.
54. Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, et al. Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell 2008, 135:749-762.
55. Sanz E, Yang L, Su T, Morris DR, McKnight GS, Amieux PS. Cell-type-specific isolation of ribosome-associated mRNA from complex tissues. Proc Natl Acad Sci U S A 2009, 106:13939-13944.
56. Deal RB, Henikoff S. The INTACT method for cell type-specific gene expression and chromatin profiling in Arabidopsis thaliana. Nat Protoc 2011, 6:56-68.
57. Gay L, Miller MR, Ventura PB, Devasthali V, Vue Z, Thompson HL, Temple S, Zong H, Cleary MD, Stankunas K, et al. Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA. Genes Dev 2013, 27:98-115.