Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes

Human Molecular Genetics

Volumn 18, Issue 21, 2009, Pages 4171-4179

  Pauws, Erwin ^a   Hoshino, Aya ^a   Bentley, Lucy ^a   Prajapati, Suresh ^b   Keller, Charles ^b   Hammond, Peter ^a   Martinez Barbera, Juan Pedro ^a   Moore, Gudrun E ^a   Stanier, Philip ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX22; UNCLASSIFIED DRUG; TBX22 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANKYLOGLOSSIA; ARTICLE; BREATHING DISORDER; CELL MATURATION; CHOANA ATRESIA; CLEFT PALATE; CRANIOFACIAL MALFORMATION; EMBRYO; FEEDING DISORDER; FEMALE; HARD PALATE; LETHALITY; MALE; MESENCHYME; MOUSE; MOUSE MUTANT; NONHUMAN; OSSIFICATION; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; CONGENITAL MALFORMATION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IN SITU HYBRIDIZATION; METABOLISM; MULTIPLE MALFORMATION SYNDROME; MUTATION; PALATE; PATHOLOGY; TONGUE;

MUS;

ABNORMALITIES, MULTIPLE; ANIMALS; CHOANAL ATRESIA; CLEFT PALATE; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IN SITU HYBRIDIZATION; LINGUAL FRENUM; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; OSTEOBLASTS; PALATE; PHENOTYPE; T-BOX DOMAIN PROTEINS;

EID: 70349986395     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp368     Document Type: Article

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