Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro

Molecular and Cellular Endocrinology

Volumn 404, Issue , 2015, Pages 1-8

  Kim, Tae Kang ^a   Lin, Zongtao ^a   Tidwell, William J ^a   Li, We ^a   Slominski, Andrzej T ^a,b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

5 methoxytryptamine; 6 hydroxymelatonin; AFMK; Epidermis; Melanocytes; Melatonin

Indexed keywords

5 METHOXYTRYPTAMINE; 6 HYDROXYMELATONIN; DNA; MELATONIN; MONOPHENOL MONOOXYGENASE; N1 ACETYL N2 FORMYL 5 METHOXYKYNURAMINE; TYROSINE; UNCLASSIFIED DRUG; 6-HYDROXYMELATONIN; KYNURAMINE; N-ACETYL-N-FORMYL-5-METHOXYKYNURENAMINE; PROTEIN TYROSINE KINASE;

ADULT; AFRICAN AMERICAN; AGED; ARTICLE; BIOACCUMULATION; CANCER GROWTH; CAUCASIAN; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; DOSE RESPONSE; ENZYME ACTIVITY; EPIDERMIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MELANOCYTE; MELANOGENESIS; MELANOMA CELL; PHENOTYPE; AGE; ANALOGS AND DERIVATIVES; CELL CULTURE; CYTOLOGY; ENZYMOLOGY; MELANOMA; METABOLISM; MIDDLE AGED; SEX DIFFERENCE; SKIN TUMOR; VERY ELDERLY;

5-METHOXYTRYPTAMINE; ADULT; AFRICAN AMERICANS; AGE FACTORS; AGED; AGED, 80 AND OVER; CELL PROLIFERATION; CELLS, CULTURED; EPIDERMIS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; IN VITRO TECHNIQUES; KYNURAMINE; MALE; MELANOCYTES; MELANOMA; MELATONIN; MIDDLE AGED; PROTEIN-TYROSINE KINASES; SEX FACTORS; SKIN NEOPLASMS;

EID: 84922273922     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2014.07.024     Document Type: Article

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