Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient

Journal of Hepatology

Volumn 62, Issue 2, 2015, Pages 486-491

  Qasim, Waseem ^a   Brunetto, Maurizia ^b   Gehring, Adam J ^c   Xue, Shao An ^a   Schurich, Anna ^a   Khakpoor, Atefeh ^d   Zhan, Hong ^a   Ciccorossi, Pietro ^b   Gilmour, Kimberly ^a   Cavallone, Daniela ^b   Moriconi, Francesco ^b   Farzhenah, Farzin ^e   Mazzoni, Alessandro ^b   Chan, Lucas ^e   Morris, Emma ^a   Thrasher, Adrian ^a   Maini, Mala K ^a   Bonino, Ferruccio ^b   Stauss, Hans ^a   Bertoletti, Antonio ^c,d,f  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY HOSPITAL OF PISA   (Italy)

^c AGENCY FOR SCIENCE   (Singapore)

^d DUKE NUS MEDICAL SCHOOL   (Singapore)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

HBV specific CD8 T cells; Liver cancer; T cell therapy

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA FETOPROTEIN; CHEMOKINE; GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; T LYMPHOCYTE RECEPTOR; TACROLIMUS; TENOFOVIR; TUMOR ANTIGEN; VIRUS DNA; IMMUNOSUPPRESSIVE AGENT; LYMPHOCYTE ANTIGEN RECEPTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALPHA FETOPROTEIN BLOOD LEVEL; ANTIGEN EXPRESSION; ANTIVIRAL THERAPY; ARTICLE; AUTOLOGOUS T CELL RECEPTOR REDIRECTED T CELL; BLOOD ANALYSIS; BRAIN METASTASIS; CANCER GROWTH; CANCER IMMUNOTHERAPY; CANCER RECURRENCE; CASE REPORT; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL SURVIVAL; CELL THERAPY; CELL TRANSFER; CONFUSION; CREATININE BLOOD LEVEL; CYTOKINE RELEASE; DEGRANULATION ASSAY; ENDOSCOPIC BIOPSY; HEPATITIS; HUMAN; HUMAN CELL; IMMUNOHISTOLOGY; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; IN VIVO STUDY; LETHARGY; LEUKAPHERESIS; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; LYMPHOCYTE; MALE; MEDICAL HISTORY; METASTASIS; PALLIATIVE THERAPY; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SEROLOGY; T LYMPHOCYTE; TRANSBRONCHIAL BIOPSY; AGED; CARCINOMA, HEPATOCELLULAR; FATALITY; FOLLOW UP; IMMUNOLOGY; IMMUNOTHERAPY; LIVER NEOPLASMS; METABOLISM; PATHOLOGY; PROCEDURES; SECONDARY;

AGED; CARCINOMA, HEPATOCELLULAR; FATAL OUTCOME; FOLLOW-UP STUDIES; HEPATITIS B SURFACE ANTIGENS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; IMMUNOTHERAPY; LIVER NEOPLASMS; MALE; NEOPLASM METASTASIS; RECEPTORS, ANTIGEN, T-CELL; TACROLIMUS;

EID: 84922268964     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.10.001     Document Type: Article

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