-
2
-
-
80053088189
-
Current concepts hepatocellular carcinoma
-
El-Serag HB. Current concepts hepatocellular carcinoma. N Engl J Med 2011; 365:1118-1127.
-
(2011)
N Engl J Med
, vol.365
, pp. 1118-1127
-
-
El-Serag, H.B.1
-
3
-
-
78649711427
-
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes
-
Levine AJ, Puzio-Kuter AM. The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes. Science 2010;330:1340-1344.
-
(2010)
Science
, vol.330
, pp. 1340-1344
-
-
Levine, A.J.1
Puzio-Kuter, A.M.2
-
4
-
-
0025690311
-
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
-
Sladek FM, Zhong WM, Lai E, Darnell JE Jr. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev 1990;4:2353-2365.
-
(1990)
Genes Dev
, vol.4
, pp. 2353-2365
-
-
Sladek, F.M.1
Zhong, W.M.2
Lai, E.3
Darnell Jr, J.E.4
-
5
-
-
33744795211
-
Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver
-
Battle MA, Konopka G, Parviz F, Gaggl AL, Yang C, Sladek FM, et al. Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A 2006;103:8419-8424.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 8419-8424
-
-
Battle, M.A.1
Konopka, G.2
Parviz, F.3
Gaggl, A.L.4
Yang, C.5
Sladek, F.M.6
-
6
-
-
77149123633
-
Hepatocyte nuclear factor 4α attenuates hepatic fibrosis in rats
-
Yue HY, Yin C, Hou JL, Zeng X, Chen YX, Zhong W, et al. Hepatocyte nuclear factor 4α attenuates hepatic fibrosis in rats. Gut 2010;59:236-246.
-
(2010)
Gut
, vol.59
, pp. 236-246
-
-
Yue, H.Y.1
Yin, C.2
Hou, J.L.3
Zeng, X.4
Chen, Y.X.5
Zhong, W.6
-
7
-
-
56149088742
-
Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4alpha gene
-
Yin C, Lin Y, Zhang X, Chen YX, Zeng X, Yue HY, et al. Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4alpha gene. Hepatology 2008;48:1528-1539.
-
(2008)
Hepatology
, vol.48
, pp. 1528-1539
-
-
Yin, C.1
Lin, Y.2
Zhang, X.3
Chen, Y.X.4
Zeng, X.5
Yue, H.Y.6
-
8
-
-
77957344834
-
Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma
-
Ning BF, Ding J, Yin C, Zhong W, Wu K, Zeng X, et al. Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma. Cancer Res 2010;70:7640-7651.
-
(2010)
Cancer Res
, vol.70
, pp. 7640-7651
-
-
Ning, B.F.1
Ding, J.2
Yin, C.3
Zhong, W.4
Wu, K.5
Zeng, X.6
-
9
-
-
84879125455
-
Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents
-
Walesky C, Edwards G, Borude P, Gunewardena S, O'Neil M, Yoo B, et al. Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents. Hepatology 2013;57:2480-2490.
-
(2013)
Hepatology
, vol.57
, pp. 2480-2490
-
-
Walesky, C.1
Edwards, G.2
Borude, P.3
Gunewardena, S.4
O'Neil, M.5
Yoo, B.6
-
10
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
12
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008;132:344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
13
-
-
33750435582
-
NF-kappaB and the immune response
-
Hayden MS, West AP, Ghosh S. NF-kappaB and the immune response. Oncogene 2006;25:6758-6780.
-
(2006)
Oncogene
, vol.25
, pp. 6758-6780
-
-
Hayden, M.S.1
West, A.P.2
Ghosh, S.3
-
14
-
-
78650859531
-
NF-κB and STAT3 - key players in liver inflammation and cancer
-
He G, Karin M. NF-κB and STAT3 - key players in liver inflammation and cancer. Cell Res 2011;21:159-68.
-
(2011)
Cell Res
, vol.21
, pp. 159-168
-
-
He, G.1
Karin, M.2
-
15
-
-
25844459154
-
NF-kappaB: linking inflammation and immunity to cancer development and progression
-
Karin M, Greten FR. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 2005;5:749-759.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
16
-
-
0035901090
-
Inflammation and cancer: back to Virchow?
-
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001;357:539-545.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
17
-
-
84861580616
-
Cyclin G1-mediated epithelial-mesenchymal transition by way of PI3-K/Akt signaling facilitates liver cancer progression
-
Wen W, Ding J, Sun W, Fu J, Chen Y, Wu K, et al. Cyclin G1-mediated epithelial-mesenchymal transition by way of PI3-K/Akt signaling facilitates liver cancer progression. Hepatology 2012;55:1787-1798.
-
(2012)
Hepatology
, vol.55
, pp. 1787-1798
-
-
Wen, W.1
Ding, J.2
Sun, W.3
Fu, J.4
Chen, Y.5
Wu, K.6
-
18
-
-
84888304473
-
Hepatocyte nuclear factor-4α reverses malignancy of hepatocellular carcinoma through regulating miR-134 in the DLK1-DIO3 region
-
Yin C, Wang PQ, Xu WP, Yang Y, Zhang Q, Ning BF, et al. Hepatocyte nuclear factor-4α reverses malignancy of hepatocellular carcinoma through regulating miR-134 in the DLK1-DIO3 region. Hepatology. 2013;58:1964-1976.
-
(2013)
Hepatology.
, vol.58
, pp. 1964-1976
-
-
Yin, C.1
Wang, P.Q.2
Xu, W.P.3
Yang, Y.4
Zhang, Q.5
Ning, B.F.6
-
19
-
-
77749297990
-
An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB
-
Min J, Zaslavsky A, Fedele G, McLaughlin SK, Reczek EE, De Raedt T, et al. An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB. Nat Med 2010;16:286-294.
-
(2010)
Nat Med
, vol.16
, pp. 286-294
-
-
Min, J.1
Zaslavsky, A.2
Fedele, G.3
McLaughlin, S.K.4
Reczek, E.E.5
De Raedt, T.6
-
20
-
-
4344612243
-
NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
-
Huber MA, Azoitei N, Baumann B, Grünert S, Sommer A, Pehamberger H, et al. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest 2004;114:569-581.
-
(2004)
J Clin Invest
, vol.114
, pp. 569-581
-
-
Huber, M.A.1
Azoitei, N.2
Baumann, B.3
Grünert, S.4
Sommer, A.5
Pehamberger, H.6
-
21
-
-
84888291167
-
Perturbation of MicroRNA-370/Lin-28 homolog A/nuclear factor kappa B regulatory circuit contributes to the development of hepatocellular carcinoma
-
Xu WP, Yi M, Li QQ, Zhou WP, Cong WM, Yang Y, et al. Perturbation of MicroRNA-370/Lin-28 homolog A/nuclear factor kappa B regulatory circuit contributes to the development of hepatocellular carcinoma. Hepatology. 2013;58:1977-1991.
-
(2013)
Hepatology.
, vol.58
, pp. 1977-1991
-
-
Xu, W.P.1
Yi, M.2
Li, Q.Q.3
Zhou, W.P.4
Cong, W.M.5
Yang, Y.6
-
22
-
-
41249102034
-
Experimental models of hepatocellular carcinoma
-
Newell P, Villanueva A, Friedman SL, Koike K, Llovet JM. Experimental models of hepatocellular carcinoma. J Hepatol 2008;48:858-879.
-
(2008)
J Hepatol
, vol.48
, pp. 858-879
-
-
Newell, P.1
Villanueva, A.2
Friedman, S.L.3
Koike, K.4
Llovet, J.M.5
-
23
-
-
21244472975
-
IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
-
Maeda S, Kamata H, Luo JL, Leffert H, Karin M. IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 2005;121:977-990.
-
(2005)
Cell
, vol.121
, pp. 977-990
-
-
Maeda, S.1
Kamata, H.2
Luo, J.L.3
Leffert, H.4
Karin, M.5
-
24
-
-
79955979289
-
PTPN11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis
-
Bard-Chapeau EA, Li S, Ding J, Zhang SS, Zhu HH, Princen F, et al. PTPN11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis. Cancer Cell 2011;19:629-639.
-
(2011)
Cancer Cell
, vol.19
, pp. 629-639
-
-
Bard-Chapeau, E.A.1
Li, S.2
Ding, J.3
Zhang, S.S.4
Zhu, H.H.5
Princen, F.6
-
25
-
-
83255162659
-
An HNF4alpha-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis
-
Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, et al. An HNF4alpha-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell 2011;147:1233-1247.
-
(2011)
Cell
, vol.147
, pp. 1233-1247
-
-
Hatziapostolou, M.1
Polytarchou, C.2
Aggelidou, E.3
Drakaki, A.4
Poultsides, G.A.5
Jaeger, S.A.6
-
26
-
-
79952231921
-
Management of hepatocellular carcinoma: an update
-
Bruix J, Sherman M. Management of hepatocellular carcinoma: an update. Hepatology 2011;53:1020-1022.
-
(2011)
Hepatology
, vol.53
, pp. 1020-1022
-
-
Bruix, J.1
Sherman, M.2
-
27
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002;2:563-572.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
28
-
-
0034893404
-
Hepatocellular carcinoma-cause, treatment and metastasis
-
Tang ZY. Hepatocellular carcinoma-cause, treatment and metastasis. World J Gastroenterol 2001;7:445-454.
-
(2001)
World J Gastroenterol
, vol.7
, pp. 445-454
-
-
Tang, Z.Y.1
-
29
-
-
4544273428
-
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
-
Lee JS, Chu IS, Heo J, Calvisi DF, Sun Z, Roskams T, et al. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 2004;40:667-676.
-
(2004)
Hepatology
, vol.40
, pp. 667-676
-
-
Lee, J.S.1
Chu, I.S.2
Heo, J.3
Calvisi, D.F.4
Sun, Z.5
Roskams, T.6
-
30
-
-
40949087185
-
Identification of metastasis-related microRNAs in hepatocellular carcinoma
-
Budhu A, Jia HL, Forgues M, Liu CG, Goldstein D, Lam A, et al. Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 2008;47:897-907.
-
(2008)
Hepatology
, vol.47
, pp. 897-907
-
-
Budhu, A.1
Jia, H.L.2
Forgues, M.3
Liu, C.G.4
Goldstein, D.5
Lam, A.6
-
32
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
33
-
-
84856994812
-
Conflicting roles of molecules in hepatocarcinogenesis: paradigm or paradox
-
Feng GS. Conflicting roles of molecules in hepatocarcinogenesis: paradigm or paradox. Cancer Cell 2012;21:150-154.
-
(2012)
Cancer Cell
, vol.21
, pp. 150-154
-
-
Feng, G.S.1
-
34
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004;431:461-466.
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
-
35
-
-
79960061468
-
Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-κB induced matrix metalloproteinases 2 and 9 expression
-
Li J, Lau GK, Chen L, Dong SS, Lan HY, Huang XR, et al. Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-κB induced matrix metalloproteinases 2 and 9 expression. PLoS One 2011;6:e21816.
-
(2011)
PLoS One
, vol.6
-
-
Li, J.1
Lau, G.K.2
Chen, L.3
Dong, S.S.4
Lan, H.Y.5
Huang, X.R.6
-
36
-
-
84885671431
-
Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling
-
He G, Dhar D, Nakagawa H, Font-Burgada J, Ogata H, Jiang Y, et al. Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling. Cell 2013;155:384-396.
-
(2013)
Cell
, vol.155
, pp. 384-396
-
-
He, G.1
Dhar, D.2
Nakagawa, H.3
Font-Burgada, J.4
Ogata, H.5
Jiang, Y.6
-
37
-
-
84896706849
-
Multiple interactive factors in hepatocarcinogenesis
-
Ding J, Wang HY. Multiple interactive factors in hepatocarcinogenesis. Cancer Lett. 2014;346:17-23.
-
(2014)
Cancer Lett.
, vol.346
, pp. 17-23
-
-
Ding, J.1
Wang, H.Y.2
-
38
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009;139:871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
39
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004;117:927-939.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
-
40
-
-
84881002286
-
MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42
-
Wang R, Zhao N, Li S, Fang JH, Chen MX, Yang J, et al. MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42. Hepatology 2013;58:642-653.
-
(2013)
Hepatology
, vol.58
, pp. 642-653
-
-
Wang, R.1
Zhao, N.2
Li, S.3
Fang, J.H.4
Chen, M.X.5
Yang, J.6
-
41
-
-
78650861867
-
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia
-
Fabbri M, Bottoni A, Shimizu M, Spizzo R, Nicoloso MS, Rossi S, et al. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. JAMA 2011;305:59-67.
-
(2011)
JAMA
, vol.305
, pp. 59-67
-
-
Fabbri, M.1
Bottoni, A.2
Shimizu, M.3
Spizzo, R.4
Nicoloso, M.S.5
Rossi, S.6
-
42
-
-
78650204499
-
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway
-
Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, et al. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev 2010;24:2754-2759.
-
(2010)
Genes Dev
, vol.24
, pp. 2754-2759
-
-
Kent, O.A.1
Chivukula, R.R.2
Mullendore, M.3
Wentzel, E.A.4
Feldmann, G.5
Lee, K.H.6
|