-
1
-
-
80052015813
-
Molecular control of endothelial cell behaviour during blood vessel morphogenesis
-
PMID:21860391
-
Herbert SP, Stainier DY. Molecular control of endothelial cell behaviour during blood vessel morphogenesis. Nat Rev Mol Cell Biol 2011; 12:551-64; PMID:21860391; http://dx.doi.org/10.1038/ nrm3176
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 551-564
-
-
Herbert, S.P.1
Stainier, D.Y.2
-
2
-
-
80052933197
-
Basic and therapeutic aspects of angiogenesis
-
PMID:21925313
-
Potente M, Gerhardt H, Carmeliet P. Basic and therapeutic aspects of angiogenesis. Cell 2011; 146:873-87; PMID:21925313; http://dx.doi.org/10.1016/j.cell. 2011.08.039
-
(2011)
Cell
, vol.146
, pp. 873-887
-
-
Potente, M.1
Gerhardt, H.2
Carmeliet, P.3
-
3
-
-
81255188940
-
Tumor angiogenesis: Molecular pathways and therapeutic targets
-
PMID:22064426
-
Weis SM, Cheresh DA. Tumor angiogenesis: molecular pathways and therapeutic targets. Nat Med 2011; 17:1359-70; PMID:22064426; http://dx.doi.org/10.1038/nm.2537
-
(2011)
Nat Med
, vol.17
, pp. 1359-1370
-
-
Weis, S.M.1
Cheresh, D.A.2
-
4
-
-
16944362446
-
Angiogenesis in ischemic heart disease
-
PMID:9018233
-
Ware JA, Simons M. Angiogenesis in ischemic heart disease. Nat Med 1997; 3:158-64; PMID:9018233; http://dx.doi.org/10.1038/nm0297-158
-
(1997)
Nat Med
, vol.3
, pp. 158-164
-
-
Ware, J.A.1
Simons, M.2
-
5
-
-
0033387447
-
Angiogenesis in ischemic disease
-
PMID: 10695485
-
Marti HH, Risau W. Angiogenesis in ischemic disease. Thromb Haemost 1999; 82 Suppl 1:44-52; PMID: 10695485
-
(1999)
Thromb Haemost
, vol.82
, Issue.1
, pp. 44-52
-
-
Marti, H.H.1
Risau, W.2
-
6
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
PMID:21593862
-
Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011; 473:298-307; PMID:21593862; http://dx.doi.org/10.1038/ nature10144
-
(2011)
Nature
, vol.473
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
7
-
-
34249689753
-
Molecular regulation of angiogenesis and lymphangiogenesis
-
PMID:17522591
-
Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol cell Biol 2007; 8:464-78; PMID:17522591; http://dx.doi.org/10.1038/nrm2183
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
8
-
-
33847046849
-
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
-
PMID:17259973
-
Hellstrom M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nat 2007; 445:776-80; PMID:17259973; http://dx.doi.org/10.1038/nature05571
-
(2007)
Nat
, vol.445
, pp. 776-780
-
-
Hellstrom, M.1
Phng, L.K.2
Hofmann, J.J.3
Wallgard, E.4
Coultas, L.5
Lindblom, P.6
Alva, J.7
Nilsson, A.K.8
Karlsson, L.9
Gaiano, N.10
-
9
-
-
77957607057
-
Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
-
PMID:20871601
-
Jakobsson L, Franco CA, Bentley K, Collins RT, Ponsioen B, Aspalter IM, Rosewell I, Busse M, Thurston G, Medvinsky A, et al. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat Cell Biol 2010; 12:943-53; PMID:20871601; http://dx.doi.org/10.1038/ncb2103
-
(2010)
Nat Cell Biol
, vol.12
, pp. 943-953
-
-
Jakobsson, L.1
Franco, C.A.2
Bentley, K.3
Collins, R.T.4
Ponsioen, B.5
Aspalter, I.M.6
Rosewell, I.7
Busse, M.8
Thurston, G.9
Medvinsky, A.10
-
10
-
-
33847635620
-
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative 14 regulator of angiogenic sprouting
-
PMID:17296940
-
Lobov IB, Renard RA, Papadopoulos N, Gale NW, Thurston G, Yancopoulos GD, Wiegand SJ. Delta-like ligand 4 (Dll4) is induced by VEGF as a negative 14 regulator of angiogenic sprouting. Proc Natl Acad Sci U S A 2007; 104:3219-24; PMID:17296940; http://dx.doi.org/10.1073/pnas.0611206104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3219-3224
-
-
Lobov, I.B.1
Renard, R.A.2
Papadopoulos, N.3
Gale, N.W.4
Thurston, G.5
Yancopoulos, G.D.6
Wiegand, S.J.7
-
11
-
-
84897536435
-
The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis
-
PMID:24658686
-
Bentley K, Franco CA, Philippides A, Blanco R, Dierkes M, Gebala V, Stanchi F, Jones M, Aspalter IM, Cagna G, et al. The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis. Nat cell Biol 2014; 16(4):309-21; PMID:24658686
-
(2014)
Nat Cell Biol
, vol.16
, Issue.4
, pp. 309-321
-
-
Bentley, K.1
Franco, C.A.2
Philippides, A.3
Blanco, R.4
Dierkes, M.5
Gebala, V.6
Stanchi, F.7
Jones, M.8
Aspalter, I.M.9
Cagna, G.10
-
12
-
-
50149083752
-
Mammalian Rho GTPases: New insights into their functions from in vivo studies
-
PMID:18719708
-
Heasman SJ, Ridley AJ. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol cell Biol 2008; 9:690-701; PMID:18719708; http://dx.doi.org/10.1038/nrm2476
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
13
-
-
35248893422
-
What tangled webs they weave: Rho-GTPase control of angiogenesis
-
PMID:17530172
-
Bryan BA, D’Amore PA. What tangled webs they weave: Rho-GTPase control of angiogenesis. Cell Mol life Sci 2007; 64:2053-65; PMID:17530172; http://dx.doi.org/10.1007/s00018-007-7008-z
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 2053-2065
-
-
Bryan, B.A.1
D’Amore, P.A.2
-
14
-
-
84892414410
-
Vascular RhoJ is an effective and selective target for tumor angiogenesis and vascular disruption
-
PMID:24434213
-
Kim C, Yang H, Fukushima Y, Saw PE, Lee J, Park JS, Park I, Jung J, Kataoka H, Lee D, et al. Vascular RhoJ is an effective and selective target for tumor angiogenesis and vascular disruption. Cancer Cell 2014; 25:102-17; PMID:24434213; http://dx.doi.org/10.1016/j.ccr.2013.12.010
-
(2014)
Cancer Cell
, vol.25
, pp. 102-117
-
-
Kim, C.1
Yang, H.2
Fukushima, Y.3
Saw, P.E.4
Lee, J.5
Park, J.S.6
Park, I.7
Jung, J.8
Kataoka, H.9
Lee, D.10
-
15
-
-
44449178868
-
Rho GTPases in cancer cell biology
-
PMID:18460342
-
Vega FM, Ridley AJ. Rho GTPases in cancer cell biology. FEBS Lett 2008; 582:2093-101; PMID:18460342; http://dx.doi.org/10.1016/j.febslet.2008.04.039
-
(2008)
FEBS Lett
, vol.582
, pp. 2093-2101
-
-
Vega, F.M.1
Ridley, A.J.2
-
16
-
-
12344329603
-
RHO SIGNALING in vascular diseases
-
PMID: 15616164
-
Seasholtz TM, Brown JH. RHO SIGNALING in vascular diseases. Mol Interv 2004; 4:348-57; PMID: 15616164; http://dx.doi.org/10.1124/mi.4.6.8
-
(2004)
Mol Interv
, vol.4
, pp. 348-357
-
-
Seasholtz, T.M.1
Brown, J.H.2
-
17
-
-
79952455505
-
The VEGF/Rho GTPase signalling pathway: A promising target for anti-angiogenic/anti-invasion therapy
-
PMID:21262381
-
van der Meel R, Symons MH, Kudernatsch R, Kok RJ, Schiffelers RM, Storm G, Gallagher WM, Byrne AT. The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy. Drug Discov Today 2011; 16:219-28; PMID:21262381; http://dx.doi.org/10.1016/j.drudis.2011.01.005
-
(2011)
Drug Discov Today
, vol.16
, pp. 219-228
-
-
Van Der Meel, R.1
Symons, M.H.2
Kudernatsch, R.3
Kok, R.J.4
Schiffelers, R.M.5
Storm, G.6
Gallagher, W.M.7
Byrne, A.T.8
-
18
-
-
0036488510
-
RHO-GTPases and cancer
-
PMID:12635176
-
Sahai E, Marshall CJ. RHO-GTPases and cancer. Nat Rev Cancer 2002; 2:133-42; PMID:12635176; http://dx.doi.org/10.1038/nrc725
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 133-142
-
-
Sahai, E.1
Marshall, C.J.2
-
19
-
-
84905364059
-
Rho guanine nucleotide exchange factors: Regulators of Rho GTPase activity in development and disease
-
PMID:24037532
-
Cook DR, Rossman KL, Der CJ. Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease. Oncogene 2014; 33:4021-4035; PMID:24037532; http://dx.doi.org/10.1038/onc.2013.362
-
(2014)
Oncogene
, vol.33
, pp. 4021-4035
-
-
Cook, D.R.1
Rossman, K.L.2
Der, C.J.3
-
20
-
-
44849097747
-
DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma
-
PMID:18519636
-
Xue W, Krasnitz A, Lucito R, Sordella R, Vanaelst L, Cordon-Cardo C, Singer S, Kuehnel F, Wigler M, Powers S, et al. DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes Dev 2008; 22:1439-44; PMID:18519636; http://dx.doi.org/10.1101/gad.1672608
-
(2008)
Genes Dev
, vol.22
, pp. 1439-1444
-
-
Xue, W.1
Krasnitz, A.2
Lucito, R.3
Sordella, R.4
Vanaelst, L.5
Cordon-Cardo, C.6
Singer, S.7
Kuehnel, F.8
Wigler, M.9
Powers, S.10
-
21
-
-
0034548009
-
DLC-1 is deleted in primary hepatocellular carcinoma and exerts inhibitory effects on the proliferation of hepatoma cell lines with deleted DLC-1
-
PMID:11118037
-
Ng IO, Liang ZD, Cao L, Lee TK. DLC-1 is deleted in primary hepatocellular carcinoma and exerts inhibitory effects on the proliferation of hepatoma cell lines with deleted DLC-1. Cancer Res 2000; 60:6581-4; PMID:11118037
-
(2000)
Cancer Res
, vol.60
, pp. 6581-6584
-
-
Ng, I.O.1
Liang, Z.D.2
Cao, L.3
Lee, T.K.4
-
22
-
-
0037461932
-
DLC-1 gene inhibits human breast cancer cell growth and in vivo tumorigenicity
-
PMID:12545165
-
Yuan BZ, Zhou X, Durkin ME, Zimonjic DB, Gumundsdottir K, Eyfjord JE, Thorgeirsson SS, Popescu NC. DLC-1 gene inhibits human breast cancer cell growth and in vivo tumorigenicity. Oncogene 2003; 22:445-50; PMID:12545165; http://dx.doi.org/10.1038/sj.onc.1206064
-
(2003)
Oncogene
, vol.22
, pp. 445-450
-
-
Yuan, B.Z.1
Zhou, X.2
Durkin, M.E.3
Zimonjic, D.B.4
Gumundsdottir, K.5
Eyfjord, J.E.6
Thorgeirsson, S.S.7
Popescu, N.C.8
-
23
-
-
78149419279
-
Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells
-
PMID:20664062
-
Coleman PR, Hahn CN, Grimshaw M, Lu Y, Li X, Brautigan PJ, Beck K, Stocker R, Vadas MA, Gamble JR. Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells. Blood 2010; 116:4016-24; PMID:20664062; http://dx.doi.org/10.1182/blood-2009-11-252700
-
(2010)
Blood
, vol.116
, pp. 4016-4024
-
-
Coleman, P.R.1
Hahn, C.N.2
Grimshaw, M.3
Lu, Y.4
Li, X.5
Brautigan, P.J.6
Beck, K.7
Stocker, R.8
Vadas, M.A.9
Gamble, J.R.10
-
24
-
-
25144477327
-
Expression profiling reveals functionally important genes and coordinately regulated signaling pathway genes during in vitro angiogenesis
-
PMID:15840639
-
Hahn CN, Su ZJ, Drogemuller CJ, Tsykin A, Waterman SR, Brautigan PJ, Yu S, Kremmidiotis G, Gardner A, Solomon PJ, et al. Expression profiling reveals functionally important genes and coordinately regulated signaling pathway genes during in vitro angiogenesis. Physioll Genomics 2005; 22:57-69; PMID:15840639; http://dx.doi.org/10.1152/physiolgenomics.00278.2004
-
(2005)
Physioll Genomics
, vol.22
, pp. 57-69
-
-
Hahn, C.N.1
Su, Z.J.2
Drogemuller, C.J.3
Tsykin, A.4
Waterman, S.R.5
Brautigan, P.J.6
Yu, S.7
Kremmidiotis, G.8
Gardner, A.9
Solomon, P.J.10
-
25
-
-
84901392705
-
Rho GAPs and GEFs: Controling switches in endothelial cell adhesion
-
PMID:24622613
-
van Buul JD, Geerts D, Huveneers S. Rho GAPs and GEFs: Controling switches in endothelial cell adhesion. Cell Adh Migr 2014; 8:108-124; PMID:24622613; http://dx.doi.org/10.4161/cam.27599
-
(2014)
Cell Adh Migr
, vol.8
, pp. 108-124
-
-
Van Buul, J.D.1
Geerts, D.2
Huveneers, S.3
-
26
-
-
80054683063
-
ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility
-
PMID:21865595
-
Maeda M, Hasegawa H, Hyodo T, Ito S, Asano E, Yuang H, Funasaka K, Shimokata K, Hasegawa Y, Hamaguchi M, et al. ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility. Mol Biol Cell 2011; 22:3840-52; PMID:21865595; http://dx.doi.org/10.1091/mbc.E11-04-0364
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3840-3852
-
-
Maeda, M.1
Hasegawa, H.2
Hyodo, T.3
Ito, S.4
Asano, E.5
Yuang, H.6
Funasaka, K.7
Shimokata, K.8
Hasegawa, Y.9
Hamaguchi, M.10
-
27
-
-
30744476478
-
Retinal angiogenesis in development and disease
-
PMID: 16355161
-
Gariano RF, Gardner TW. Retinal angiogenesis in development and disease. Nature 2005; 438:960-6; PMID: 16355161; http://dx.doi.org/10.1038/nature04482
-
(2005)
Nature
, vol.438
, pp. 960-966
-
-
Gariano, R.F.1
Gardner, T.W.2
-
28
-
-
59649085554
-
Angiogenesis: A team effort coordinated by notch
-
PMID:19217422
-
Phng LK, Gerhardt H. Angiogenesis: a team effort coordinated by notch. Dev Cell 2009; 16:196-208; PMID:19217422; http://dx.doi.org/10.1016/j.devcel.2009.01.015
-
(2009)
Dev Cell
, vol.16
, pp. 196-208
-
-
Phng, L.K.1
Gerhardt, H.2
-
29
-
-
0029981294
-
Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization
-
PMID:8630677
-
Rabiet MJ, Plantier JL, Rival Y, Genoux Y, Lampugnani MG, Dejana E. Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization. Arterioscler Thromb Vasc Biol 1996; 16:488-96; PMID:8630677; http://dx.doi.org/10.1161/01.ATV.16.3.488
-
(1996)
Arterioscler Thromb Vasc Biol
, vol.16
, pp. 488-496
-
-
Rabiet, M.J.1
Plantier, J.L.2
Rival, Y.3
Genoux, Y.4
Lampugnani, M.G.5
Dejana, E.6
-
30
-
-
0034730784
-
Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions
-
PMID:11009566
-
Gamble JR, Drew J, Trezise L, Underwood A, Parsons M, Kasminkas L, Rudge J, Yancopoulos G, Vadas MA. Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions. Circ Res 2000; 87:603-7; PMID:11009566; http://dx.doi.org/10.1161/01.RES.87.7.603
-
(2000)
Circ Res
, vol.87
, pp. 603-607
-
-
Gamble, J.R.1
Drew, J.2
Trezise, L.3
Underwood, A.4
Parsons, M.5
Kasminkas, L.6
Rudge, J.7
Yancopoulos, G.8
Vadas, M.A.9
-
31
-
-
0037324359
-
Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro
-
PMID:
-
van Nieuw Amerongen GP, Koolwijk P, Versteilen A, van Hinsbergh VW. Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro. Arterioscler Thromb Vasc Biol 2003; 23:211-7; PMID: http://dx.doi.org/10.1161/01.ATV.0000054198.68894.88
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 211-217
-
-
Van Nieuw Amerongen, G.P.1
Koolwijk, P.2
Versteilen, A.3
Van Hinsbergh, V.W.4
-
32
-
-
84871954875
-
VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx
-
PMID:23253477
-
Ngok SP, Geyer R, Liu M, Kourtidis A, Agrawal S, Wu C, Seerapu HR, Lewis-Tuffin LJ, Moodie KL, Huveldt D, et al. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. J Cell Biol 2012; 199:1103-15; PMID:23253477; http://dx.doi.org/10.1083/jcb.201207009
-
(2012)
J Cell Biol
, vol.199
, pp. 1103-1115
-
-
Ngok, S.P.1
Geyer, R.2
Liu, M.3
Kourtidis, A.4
Agrawal, S.5
Wu, C.6
Seerapu, H.R.7
Lewis-Tuffin, L.J.8
Moodie, K.L.9
Huveldt, D.10
-
33
-
-
84859992640
-
Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling
-
PMID:22391038
-
Huveneers S, Oldenburg J, Spanjaard E, van der Krogt G, Grigoriev I, Akhmanova A, Rehmann H, de Rooij J. Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling. J Cell Bioly 2012; 196:641-52; PMID:22391038; http://dx.doi.org/10.1083/jcb.201108120
-
(2012)
J Cell Bioly
, vol.196
, pp. 641-652
-
-
Huveneers, S.1
Oldenburg, J.2
Spanjaard, E.3
Van Der Krogt, G.4
Grigoriev, I.5
Akhmanova, A.6
Rehmann, H.7
De Rooij, J.8
-
34
-
-
0037216703
-
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: Implications for modulating arteriogenesis and angiogenesis
-
PMID:12482957
-
Liu ZJ, Shirakawa T, Li Y, Soma A, Oka M, Dotto GP, Fairman RM, Velazquez OC, Herlyn M. Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol 2003; 23:14-25; PMID:12482957; http://dx.doi.org/10.1128/MCB.23.1.14-25.2003
-
(2003)
Mol Cell Biol
, vol.23
, pp. 14-25
-
-
Liu, Z.J.1
Shirakawa, T.2
Li, Y.3
Soma, A.4
Oka, M.5
Dotto, G.P.6
Fairman, R.M.7
Velazquez, O.C.8
Herlyn, M.9
-
35
-
-
84877117416
-
Conundrum, an ARHGAP18 orthologue, regulates RhoA and proliferation through interactions with Moesin
-
PMID:23468526
-
Neisch AL, Formstecher E, Fehon RG. Conundrum, an ARHGAP18 orthologue, regulates RhoA and proliferation through interactions with Moesin. Mol Biol Cell 2013; 24:1420-33; PMID:23468526; http://dx.doi.org/10.1091/mbc.E12-11-0800
-
(2013)
Mol Biol Cell
, vol.24
, pp. 1420-1433
-
-
Neisch, A.L.1
Formstecher, E.2
Fehon, R.G.3
-
36
-
-
80053410497
-
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis
-
PMID:21911940
-
Akilesh S, Suleiman H, Yu H, Stander MC, Lavin P, Gbadegesin R, Antignac C, Pollak M, Kopp JB, Winn MP, et al. Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. J Clin Invest 2011; 121:4127-37; PMID:21911940; http://dx.doi.org/10.1172/JCI46458
-
(2011)
J Clin Invest
, vol.121
, pp. 4127-4137
-
-
Akilesh, S.1
Suleiman, H.2
Yu, H.3
Stander, M.C.4
Lavin, P.5
Gbadegesin, R.6
Antignac, C.7
Pollak, M.8
Kopp, J.B.9
Winn, M.P.10
-
37
-
-
14844322275
-
Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton
-
PMID:15611138
-
Lavelin I, Geiger B. Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton. J Biol Chem 2005; 280:7178-85; PMID:15611138; http://dx.doi.org/10.1074/jbc.M411990200
-
(2005)
J Biol Chem
, vol.280
, pp. 7178-7185
-
-
Lavelin, I.1
Geiger, B.2
-
38
-
-
4344561026
-
A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis
-
PMID:15302923
-
Su ZJ, Hahn CN, Goodall GJ, Reck NM, Leske AF, Davy A, Kremmidiotis G, Vadas MA, Gamble JR. A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis. Proc Natl Acad Sci U S A 2004; 101:12212-7; PMID:15302923; http://dx.doi.org/10.1073/pnas.0404631101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12212-12217
-
-
Su, Z.J.1
Hahn, C.N.2
Goodall, G.J.3
Reck, N.M.4
Leske, A.F.5
Davy, A.6
Kremmidiotis, G.7
Vadas, M.A.8
Gamble, J.R.9
-
39
-
-
6344231714
-
Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility
-
PMID:15501444
-
Wheeler AP, Ridley AJ. Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility. Exp Cell Res 2004; 301:43-9; PMID:15501444; http://dx.doi.org/10.1016/j.yexcr.2004.08.012
-
(2004)
Exp Cell Res
, vol.301
, pp. 43-49
-
-
Wheeler, A.P.1
Ridley, A.J.2
-
40
-
-
24344486013
-
RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
-
PMID:16107613
-
Hakem A, Sanchez-Sweatman O, You-Ten A, Duncan G, Wakeham A, Khokha R, Mak TW. RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis. Genes Dev 2005; 19:1974-9; PMID:16107613; http://dx.doi.org/10.1101/gad.1310805
-
(2005)
Genes Dev
, vol.19
, pp. 1974-1979
-
-
Hakem, A.1
Sanchez-Sweatman, O.2
You-Ten, A.3
Duncan, G.4
Wakeham, A.5
Khokha, R.6
Mak, T.W.7
-
41
-
-
0034667370
-
A novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype
-
PMID:11059780
-
van Golen KL, Wu ZF, Qiao XT, Bao LW, Merajver SD. RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype. Cancer Res 2000; 60:5832-8; PMID:11059780
-
(2000)
Cancer Res
, vol.60
, pp. 5832-5838
-
-
Van Golen, K.L.1
Wu, Z.F.2
Qiao, X.T.3
Bao, L.W.4
Merajver, S.D.5
Gtpase, R.6
-
42
-
-
9244237677
-
Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma
-
PMID:15574779
-
Simpson KJ, Dugan AS, Mercurio AM. Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma. Cancer Res 2004; 64:8694-701; PMID:15574779; http://dx.doi.org/10.1158/0008-5472.CAN-04-2247
-
(2004)
Cancer Res
, vol.64
, pp. 8694-8701
-
-
Simpson, K.J.1
Dugan, A.S.2
Mercurio, A.M.3
-
43
-
-
33750594388
-
Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma
-
PMID:16715134
-
Bellovin DI, Simpson KJ, Danilov T, Maynard E, Rimm DL, Oettgen P, Mercurio AM. Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma. Oncogene 2006; 25:6959-67; PMID:16715134; http://dx.doi.org/10.1038/sj.onc.1209682
-
(2006)
Oncogene
, vol.25
, pp. 6959-6967
-
-
Bellovin, D.I.1
Simpson, K.J.2
Danilov, T.3
Maynard, E.4
Rimm, D.L.5
Oettgen, P.6
Mercurio, A.M.7
-
44
-
-
0036305635
-
ROCK and Dia have opposing effects on adherens junctions downstream of Rho
-
PMID:11992112
-
Sahai E, Marshall CJ. ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat Cell Biol 2002; 4:408-15; PMID:11992112; http://dx.doi.org/10.1038/ncb796
-
(2002)
Nat Cell Biol
, vol.4
, pp. 408-415
-
-
Sahai, E.1
Marshall, C.J.2
-
45
-
-
79958232399
-
RhoA and RhoC have distinct roles in migration and invasion by acting through different targets
-
PMID:21576392
-
Vega FM, Fruhwirth G, Ng T, Ridley AJ. RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. J Cell Biol 2011; 193:655-65; PMID:21576392; http://dx.doi.org/10.1083/jcb.201011038
-
(2011)
J Cell Biol
, vol.193
, pp. 655-665
-
-
Vega, F.M.1
Fruhwirth, G.2
Ng, T.3
Ridley, A.J.4
-
46
-
-
77951587879
-
Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC
-
PMID: 20101212
-
Kitzing TM, Wang Y, Pertz O, Copeland JW, Grosse R. Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC. Oncogene 2010; 29:2441-8; PMID: 20101212; http://dx.doi.org/10.1038/onc.2009.515
-
(2010)
Oncogene
, vol.29
, pp. 2441-2448
-
-
Kitzing, T.M.1
Wang, Y.2
Pertz, O.3
Copeland, J.W.4
Grosse, R.5
-
47
-
-
78149422176
-
Identification and functional analysis of endothelial tip cell-enriched genes
-
PMID:20705756
-
del Toro R, Prahst C, Mathivet T, Siegfried G, Kaminker JS, Larrivee B, Breant C, Duarte A, Takakura N, Fukamizu A, et al. Identification and functional analysis of endothelial tip cell-enriched genes. Blood 2010; 116:4025-33; PMID:20705756; http://dx.doi.org/10.1182/blood-2010-02-270819
-
(2010)
Blood
, vol.116
, pp. 4025-4033
-
-
Del Toro, R.1
Prahst, C.2
Mathivet, T.3
Siegfried, G.4
Kaminker, J.S.5
Larrivee, B.6
Breant, C.7
Duarte, A.8
Takakura, N.9
Fukamizu, A.10
-
48
-
-
77954669022
-
Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching
-
PMID: 20154215
-
Strasser GA, Kaminker JS, Tessier-Lavigne M. Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching. Blood 2010; 115:5102-10; PMID: 20154215; http://dx.doi.org/10.1182/blood-2009-07-230284
-
(2010)
Blood
, vol.115
, pp. 5102-5110
-
-
Strasser, G.A.1
Kaminker, J.S.2
Tessier-Lavigne, M.3
-
49
-
-
84881590742
-
Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB
-
PMID:23633549
-
Uebelhoer M, Natynki M, Kangas J, Mendola A, Nguyen HL, Soblet J, Godfraind C, Boon LM, Eklund L, Limaye N, et al. Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB. Hum Mol Genet 2013; 22:3438-48; PMID:23633549; http://dx.doi.org/10.1093/hmg/ddt198
-
(2013)
Hum Mol Genet
, vol.22
, pp. 3438-3448
-
-
Uebelhoer, M.1
Natynki, M.2
Kangas, J.3
Mendola, A.4
Nguyen, H.L.5
Soblet, J.6
Godfraind, C.7
Boon, L.M.8
Eklund, L.9
Limaye, N.10
-
50
-
-
65549165975
-
Genetic alterations and oncogenic pathways associated with breast cancer subtypes
-
PMID:19372580
-
Hu X, Stern HM, Ge L, O’Brien C, Haydu L, Honchell CD, Haverty PM, Peters BA, Wu TD, Amler LC, et al. Genetic alterations and oncogenic pathways associated with breast cancer subtypes. Mol Cancer Res 2009; 7:511-22; PMID:19372580; http://dx.doi.org/10.1158/1541-7786.MCR-08-0107
-
(2009)
Mol Cancer Res
, vol.7
, pp. 511-522
-
-
Hu, X.1
Stern, H.M.2
Ge, L.3
O’Brien, C.4
Haydu, L.5
Honchell, C.D.6
Haverty, P.M.7
Peters, B.A.8
Wu, T.D.9
Amler, L.C.10
-
51
-
-
80053174988
-
Genomic and phenotypic analysis of BRCA2 mutated breast cancers reveals co-occurring changes linked to progression
-
PMID:21958427
-
Stefansson OA, Jonasson JG, Olafsdottir K, Bjarnason H, Th Johannsson O, Bodvarsdottir SK, Valgeirsdottir S, Eyfjord JE. Genomic and phenotypic analysis of BRCA2 mutated breast cancers reveals co-occurring changes linked to progression. Breast Cancer Res 2011; 13:R95; PMID:21958427; http://dx.doi.org/10.1186/bcr3020
-
(2011)
Breast Cancer Res
, vol.13
, pp. R95
-
-
Stefansson, O.A.1
Jonasson, J.G.2
Olafsdottir, K.3
Bjarnason, H.4
Th Johannsson, O.5
Bodvarsdottir, S.K.6
Valgeirsdottir, S.7
Eyfjord, J.E.8
-
52
-
-
78651330430
-
COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
-
PMID:20952405
-
Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, Jia M, Shepherd R, Leung K, Menzies A, et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic acids Res 2011; 39:D945-50; PMID:20952405; http://dx.doi.org/10.1093/nar/gkq929
-
(2011)
Nucleic Acids Res
, vol.39
, pp. D945-D950
-
-
Forbes, S.A.1
Bindal, N.2
Bamford, S.3
Cole, C.4
Kok, C.Y.5
Beare, D.6
Jia, M.7
Shepherd, R.8
Leung, K.9
Menzies, A.10
-
53
-
-
84862520770
-
Fiji: An open-source platform for biological-image analysis
-
PMID:22743772
-
Schindelin J, Arganda-Carreras I, Frise E, Kaynig V, Longair M, Pietzsch T, Preibisch S, Rueden C, Saalfeld S, Schmid B, et al. Fiji: an open-source platform for biological-image analysis. Nat Methods 2012; 9:676-82; PMID:22743772; http://dx.doi.org/10.1038/nmeth.2019
-
(2012)
Nat Methods
, vol.9
, pp. 676-682
-
-
Schindelin, J.1
Arganda-Carreras, I.2
Frise, E.3
Kaynig, V.4
Longair, M.5
Pietzsch, T.6
Preibisch, S.7
Rueden, C.8
Saalfeld, S.9
Schmid, B.10
-
54
-
-
84861151846
-
Use of the mouse aortic ring assay to study angiogenesis
-
Baker M, Robinson SD, Lechertier T, Barber PR, Tavora B, D’Amico G, Jones DT, Vojnovic B, Hodivala-Dilke K. Use of the mouse aortic ring assay to study angiogenesis. Nat Protoc 2012; 7:89-104; http://dx.doi.org/10.1038/nprot.2011.435
-
(2012)
Nat Protoc
, vol.7
, pp. 89-104
-
-
Baker, M.1
Robinson, S.D.2
Lechertier, T.3
Barber, P.R.4
Tavora, B.5
D’Amico, G.6
Jones, D.T.7
Vojnovic, B.8
Hodivala-Dilke, K.9
-
55
-
-
77955860340
-
Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice
-
PMID:20725067
-
Pitulescu ME, Schmidt I, Benedito R, Adams RH. Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice. Nat Protoc 2010; 5:1518-34; PMID:20725067; http://dx.doi.org/10.1038/nprot.2010.113
-
(2010)
Nat Protoc
, vol.5
, pp. 1518-1534
-
-
Pitulescu, M.E.1
Schmidt, I.2
Benedito, R.3
Adams, R.H.4
|