Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau

Journal of Clinical Investigation

Volumn 125, Issue 2, 2015, Pages 681-686

  Santa Maria, Ismael ^a   Alaniz, Maria E ^a   Renwick, Neil ^b,e   Cela, Carolina ^a   Fulga, Tudor A ^c,f   Van Vactor, David ^c   Tuschl, Thomas ^b   Clark, Lorraine N ^a   Shelanski, Michael L ^a   McCabe, Brian D ^a,d   Crary, John F ^a,g  

^a Department of Medicine   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Harvard Medical School ^*  (United States)

^e QUEEN S UNIVERSITY   (Canada)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 219; TAU PROTEIN; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MIRN219 MICRORNA, HUMAN;

AGE DISTRIBUTION; ANIMAL EXPERIMENT; ARTICLE; AUTOPSY; BRAIN TISSUE; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; DOWN REGULATION; FRUIT FLY MODEL; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MAMMAL; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RNA BINDING; RNA PROCESSING; TAUOPATHY; TOXICITY; 3' UNTRANSLATED REGION; ALZHEIMER DISEASE; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENETICS; METABOLISM; PATHOLOGY;

3' UNTRANSLATED REGIONS; ALZHEIMER DISEASE; ANIMALS; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; HUMANS; MICRORNAS; PROTEIN BIOSYNTHESIS; TAU PROTEINS;

EID: 84922195168     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI78421     Document Type: Article

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