Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species

Phytomedicine

Volumn 22, Issue 2, 2015, Pages 262-270

  Weidner, C ^a   Rousseau, M ^a   Plauth, A ^a   Wowro, S J ^a   Fischer, C ^a   Abdel Aziz, H ^b   Sauer, S ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b Steigerwald Arzneimittelwerk GmbH   (Germany)

Author keywords

Apoptosis; Colon cancer; Functional food; Melissa officinalis; Prevention; Reactive oxygen species

Indexed keywords

ALCOHOL; CASPASE 3; CASPASE 7; CISPLATIN; CYCLIN D3; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2C; FLUOROURACIL; LIPOCORTIN 5; MELISSA OFFICINALIS EXTRACT; OXALIPLATIN; PACLITAXEL; PHOSPHATIDYLSERINE; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE; REGULATOR PROTEIN; ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; CASP7 PROTEIN, HUMAN; PLANT EXTRACT;

AGED; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; COLON CARCINOMA; CONTROLLED STUDY; DNA DETERMINATION; EXTRACELLULAR SPACE; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IC50; IMMUNOBLOTTING; INTRACELLULAR SPACE; PLANT LEAF; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL PROLIFERATION; CHEMISTRY; COLON TUMOR; DRUG EFFECTS; HT 29 CELL LINE; MELISSA OFFICINALIS; METABOLISM; PATHOLOGY;

CITRUS LIMON; MELISSA OFFICINALIS;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASE 7; CELL PROLIFERATION; COLONIC NEOPLASMS; HT29 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MELISSA; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES;

EID: 84922154571     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.12.008     Document Type: Article

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