MiRNA-34a suppresses cell proliferation and metastasis by targeting CD44 in human renal carcinoma cells

Journal of Urology

Volumn 192, Issue 4, 2014, Pages 1229-1237

  Yu, Gan ^a   Li, Heng ^a   Wang, Ji ^c   Gumireddy, Kiranmai ^d   Li, Anping ^d   Yao, Weimin ^a   Tang, Kun ^a   Xiao, Wei ^a   Hu, Junhui ^a   Xiao, Haibing ^a   Lang, Bin ^b   Ye, Zhangqun ^a   Huang, Qihong ^d   Xu, Hua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b MACAO POLYTECHNIC INSTITUTE   (Macao)

^c UNIVERSITY OF MINNESOTA   (United States)

^d WISTAR INSTITUTE   (United States)

Author keywords

carcinogenesis; carcinoma; CD44 protein; human; kidney; MIRN34 microRNA; renal cell

Indexed keywords

GENOMIC DNA; HERMES ANTIGEN; MESSENGER RNA; MICRORNA 34A; NERVE CELL ADHESION MOLECULE; OLIGONUCLEOTIDE; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VASCULOTROPIN; VIMENTIN; MICRORNA; MIRN34 MICRORNA, MOUSE; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CLONOGENESIS; COLONY FORMATION; CONTROLLED STUDY; DNA FRAGMENTATION; DNA METHYLATION; DOWN REGULATION; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CARCINOMA; LUCIFERASE ASSAY; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RENAL CANCER CELL LINE; ANIMAL; BIOSYNTHESIS; CELL TRANSFORMATION; EXPERIMENTAL NEOPLASM; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KIDNEY TUMOR; NUDE MOUSE; PATHOLOGY; SECONDARY; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD44; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KIDNEY NEOPLASMS; MICE; MICE, NUDE; MICRORNAS; NEOPLASMS, EXPERIMENTAL; REAL-TIME POLYMERASE CHAIN REACTION; RNA, NEOPLASM;

EID: 84921974673     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2014.05.094     Document Type: Article

References (29)

1. K. Gupta, J.D. Miller, and J.Z. Li Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review Cancer Treat Rev 34 2008 193
2. Y. Sato, T. Yoshizato, and Y. Shiraishi Integrated molecular analysis of clear-cell renal cell carcinoma Nat Genet 45 2013 860
3. E. Oosterwijk, W.K. Rathmell, and K. Junker Basic research in kidney cancer Eur Urol 60 2011 622
4. E. van den Berg, and T. Dijkhuizen Classification of renal cell cancer based on (cyto)genetic analysis Contrib Nephrol 128 1999 51
5. K. Junker, G. Weirich, and M.B. Amin Genetic subtyping of renal cell carcinoma by comparative genomic hybridization Recent Results Cancer Res 162 2003 169
6. D.P. Bartel MicroRNAs: target recognition and regulatory functions Cell 136 2009 215
7. B.P. Lewis, C.B. Burge, and D.P. Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 2005 15
8. G.A. Calin, and C.M. Croce MicroRNA signatures in human cancers Nat Rev Cancer 6 2006 857
9. S. Bandyopadhyay, R. Mitra, and U. Maulik Development of the human cancer microRNA network Silence 1 2010 6
10. J.W. Catto, A. Alcaraz, and A.S. Bjartell MicroRNA in prostate, bladder, and kidney cancer: a systematic review Eur Urol 59 2011 671
11. K.S. Chan, I. Espinosa, and M. Chao Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells Proc Natl Acad Sci U S A 106 2009 14016
12. C. Liu, K. Kelnar, and B. Liu The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44 Nat Med 17 2011 211
13. B.J. Jeong, Z.L. Liang, and S.M. Huang CD44 is associated with tumor recurrence and is an independent poor prognostic factor for patients with localized clear cell renal cell carcinoma after nephrectomy Exp Ther Med 3 2012 811
14. A. Bamias, M. Chorti, and C. Deliveliotis Prognostic significance of CA 125, CD44, and epithelial membrane antigen in renal cell carcinoma Urology 62 2003 368
15. W.H. Costa, R.M. Rocha, and I.W. Cunha Immunohistochemical expression of CD44s in renal cell carcinoma lacks independent prognostic significance Int Braz J Urol 38 2012 456
16. M. Altinel, E. Arpali, and N. Turhan Increased expression of CD44s in conventional renal cell carcinomas with renal vein or vena cava thrombosis. a retrospective evaluation of the expression of CD44s by immunohistochemical analysis in conventional RCC patients and in conventional RCC patients with renal vein or vena cava thrombosis Urol Int 81 2008 452
17. S.D. Lim, A.N. Young, and G.P. Paner Prognostic role of CD44 cell adhesion molecule expression in primary and metastatic renal cell carcinoma: a clinicopathologic study of 125 cases Virchows Arch 452 2008 49
18. O.W. Tawfik, B. Kramer, and B. Shideler Prognostic significance of CD44, platelet-derived growth factor receptor alpha, and cyclooxygenase 2 expression in renal cell carcinoma Arch Pathol Lab Med 131 2007 261
19. E. Yildiz, G. Gokce, and H. Kilicarslan Prognostic value of the expression of Ki-67, CD44 and vascular endothelial growth factor, and microvessel invasion, in renal cell carcinoma BJU Int 93 2004 1087
20. S.K. Basak, M.S. Veena, and S. Oh Correction: The CD44 tumorigenic subsets in lung cancer biospecimens are enriched for low miR-34a expression PLoS One 8 2013 e73195
21. L. Stankevicins, A.P. Almeida da Silva, and F. Ventura Dos Passos MiR-34a is up-regulated in response to low dose, low energy X-ray induced DNA damage in breast cells Radiat Oncol 8 2013 231
22. J. Kang, E. Kim, and W. Kim Rhamnetin and cirsiliol induce radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines J Biol Chem 288 2013 27343
23. M. Garofalo, Y.J. Jeon, and G.J. Nuovo MiR-34a/c-dependent PDGFR-alpha/beta downregulation inhibits tumorigenesis and enhances TRAIL-induced apoptosis in lung cancer PLoS One 8 2013 e67581
24. W. Cao, W. Yang, and R. Fan miR-34a regulates cisplatin-induce gastric cancer cell death by modulating PI3K/AKT/survivin pathway Tumour Biol 35 2014 1287
25. R.T. Pang, C.O. Leung, and T.M. Ye MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells Carcinogenesis 31 2010 1037
26. S. Yamamura, S. Saini, and S. Majid MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma Carcinogenesis 33 2012 294
27. D. Lodygin, V. Tarasov, and A. Epanchintsev Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer Cell Cycle 7 2008 2591
28. P. de Antonellis, C. Medaglia, and E. Cusanelli MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma PLoS One 6 2011 e24584
29. R. Golshani, L. Lopez, and V. Estrella Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44 Cancer Res 68 2008 483