-
1
-
-
33744808242
-
The immune response during hepatitis B virus infection
-
COI: 1:CAS:528:DC%2BD28XlvFCjurw%3D, PID: 16690908
-
Bertoletti A, Gehring AJ (2006) The immune response during hepatitis B virus infection. J Gen Virol 87:1439–1449
-
(2006)
J Gen Virol
, vol.87
, pp. 1439-1449
-
-
Bertoletti, A.1
Gehring, A.J.2
-
2
-
-
84889837282
-
Woodchuck hepatitis virus
-
Thomas TH, Zuckermann A, Lemon A, (eds), Blackwell Publishing Ltd, Oxford:
-
Roggendorf M, Lu M (2005) Woodchuck hepatitis virus. In: Thomas TH, Zuckermann A, Lemon A (eds) Viral hepatitis, 3rd edn. Blackwell Publishing Ltd, Oxford, pp 210–224
-
(2005)
Viral hepatitis
, pp. 210-224
-
-
Roggendorf, M.1
Lu, M.2
-
3
-
-
35448967046
-
Vaccines and immunotherapies against hepatitis B and hepatitis C viruses
-
PID: 17958650
-
Inchauspé G, Michel ML (2007) Vaccines and immunotherapies against hepatitis B and hepatitis C viruses. J Viral Hepat 14(Suppl 1):97–103
-
(2007)
J Viral Hepat
, vol.14
, pp. 97-103
-
-
Inchauspé, G.1
Michel, M.L.2
-
4
-
-
34249993791
-
Immunomodulation as an option for the treatment of chronic hepatitis B virus infection: preclinical studies in the woodchuck model
-
COI: 1:CAS:528:DC%2BD2sXltlOju7s%3D, PID: 17501692
-
Lu M, Menne S, Yang D, Xu Y, Roggendorf M (2007) Immunomodulation as an option for the treatment of chronic hepatitis B virus infection: preclinical studies in the woodchuck model. Expert Opin Investig Drugs 16:787–801
-
(2007)
Expert Opin Investig Drugs
, vol.16
, pp. 787-801
-
-
Lu, M.1
Menne, S.2
Yang, D.3
Xu, Y.4
Roggendorf, M.5
-
5
-
-
77955421572
-
Hepatitis B vaccines: protective efficacy and therapeutic potential
-
COI: 1:CAS:528:DC%2BC3cXpvV2jsrc%3D
-
Michel ML, Tiollais P (2010) Hepatitis B vaccines: protective efficacy and therapeutic potential. Pathol Biol (Paris) 58:288–295. doi:10.1016/j.patbio.2010.01.006
-
(2010)
Pathol Biol (Paris)
, vol.58
, pp. 288-295
-
-
Michel, M.L.1
Tiollais, P.2
-
6
-
-
4644313122
-
Induction or expansion of T-cell responses by a hepatitis B DNA vaccine administered to chronic HBV carriers
-
COI: 1:CAS:528:DC%2BD2cXptV2qt7g%3D, PID: 15382173
-
Mancini-Bourgine M, Fontaine H, Scott-Algara D, Pol S, Brechot C, Michel ML (2004) Induction or expansion of T-cell responses by a hepatitis B DNA vaccine administered to chronic HBV carriers. Hepatology 40:874–882
-
(2004)
Hepatology
, vol.40
, pp. 874-882
-
-
Mancini-Bourgine, M.1
Fontaine, H.2
Scott-Algara, D.3
Pol, S.4
Brechot, C.5
Michel, M.L.6
-
7
-
-
84882811237
-
Results of a phase III clinical trial with an HBsAg-HBIG immunogenic complex therapeutic vaccine for chronic hepatitis B patients: experiences and findings
-
COI: 1:CAS:528:DC%2BC3sXpsFSht7k%3D, PID: 23669281
-
Xu DZ, Wang XY, Shen XL, Gong GZ, Ren H, Guo LM, Sun AM, Xu M, Li LJ, Guo XH, Zhen Z, Wang HF, Gong HY, Xu C, Jiang N, Pan C, Gong ZJ, Zhang JM, Shang J, Xu J, Xie Q, Wu TF, Huang WX, Li YG, Xu J, Yuan ZH, Wang B, Zhao K, Wen YM, YIC Efficacy Trial Study Team (2013) Results of a phase III clinical trial with an HBsAg-HBIG immunogenic complex therapeutic vaccine for chronic hepatitis B patients: experiences and findings. J Hepatol 59:450–456
-
(2013)
J Hepatol
, vol.59
, pp. 450-456
-
-
Xu, D.Z.1
Wang, X.Y.2
Shen, X.L.3
Gong, G.Z.4
Ren, H.5
Guo, L.M.6
Sun, A.M.7
Xu, M.8
Li, L.J.9
Guo, X.H.10
Zhen, Z.11
Wang, H.F.12
Gong, H.Y.13
Xu, C.14
Jiang, N.15
Pan, C.16
Gong, Z.J.17
Zhang, J.M.18
Shang, J.19
Xu, J.20
Xie, Q.21
Wu, T.F.22
Huang, W.X.23
Li, Y.G.24
Xu, J.25
Yuan, Z.H.26
Wang, B.27
Zhao, K.28
Wen, Y.M.29
YIC Efficacy Trial Study Team30
more..
-
8
-
-
84919773476
-
Anti-HBV DNA vaccination does not prevent relapse after discontinuation of analogues in the treatment of chronic hepatitis B: a randomised trial–ANRS HB02 VAC-ADN
-
PID: 24555998
-
Fontaine H, Kahi S, Chazallon C, Bourgine M, Varaut A, Buffet C, Godon O, Meritet JF, Saïdi Y, Michel ML, Scott-Algara D, Aboulker JP, Pol S, ANRS HB02 study group (2015) Anti-HBV DNA vaccination does not prevent relapse after discontinuation of analogues in the treatment of chronic hepatitis B: a randomised trial–ANRS HB02 VAC-ADN. Gut 64:139–147
-
(2014)
Gut
, vol.64
, pp. 139-147
-
-
Fontaine, H.1
Kahi, S.2
Chazallon, C.3
Bourgine, M.4
Varaut, A.5
Buffet, C.6
Meritet, J.F.7
Godon, O.8
Saïdi, Y.9
Michel, M.L.10
Scott-Algara, D.11
Aboulker, J.P.12
Pol, S.13
ANRS HB02 Study Group14
-
9
-
-
84879549459
-
Combination of DNA prime–adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model
-
COI: 1:CAS:528:DC%2BC3sXhtFersb%2FL, PID: 23785279
-
Kosinska AD, Zhang E, Johrden L, Liu J, Seiz PL, Zhang X, Ma Z, Kemper T, Fiedler M, Glebe D, Wildner O, Dittmer U, Lu M, Roggendorf M (2013) Combination of DNA prime–adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model. PLoS Pathog 9:e1003391. doi:10.1371/journal.ppat.1003391
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003391
-
-
Kosinska, A.D.1
Zhang, E.2
Johrden, L.3
Liu, J.4
Seiz, P.L.5
Zhang, X.6
Ma, Z.7
Kemper, T.8
Fiedler, M.9
Glebe, D.10
Wildner, O.11
Dittmer, U.12
Lu, M.13
Roggendorf, M.14
-
10
-
-
84893805242
-
Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD-L1 blockade in chronic hepadnaviral infection
-
PID: 24391505
-
Liu J, Zhang E, Ma Z, Wu W, Kosinska A, Zhang X, Möller I, Seiz P, Glebe D, Wang B, Yang D, Lu M, Roggendorf M (2014) Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD-L1 blockade in chronic hepadnaviral infection. PLoS Pathog 10:e1003856. doi:10.1371/journal.ppat856.1003856
-
(2014)
PLoS Pathog
, vol.10
, pp. e1003856
-
-
Liu, J.1
Zhang, E.2
Ma, Z.3
Wu, W.4
Kosinska, A.5
Zhang, X.6
Möller, I.7
Seiz, P.8
Glebe, D.9
Wang, B.10
Yang, D.11
Lu, M.12
Roggendorf, M.13
-
11
-
-
32944464648
-
Pathogen recognition and innate immunity
-
COI: 1:CAS:528:DC%2BD28Xit1Kltb8%3D, PID: 16497588
-
Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124:783–801
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
12
-
-
0034680145
-
Toll-like receptors in the induction of the innate immune response
-
COI: 1:STN:280:DC%2BD3cvjtVOhuw%3D%3D, PID: 10963608
-
Aderem A, Ulevitch RJ (2000) Toll-like receptors in the induction of the innate immune response. Nature 406:782–787
-
(2000)
Nature
, vol.406
, pp. 782-787
-
-
Aderem, A.1
Ulevitch, R.J.2
-
13
-
-
34548459868
-
Structure and function of Toll receptors and their ligands
-
COI: 1:CAS:528:DC%2BD2sXhtVehtb7J, PID: 17362201
-
Gay NJ, Gangloff M (2007) Structure and function of Toll receptors and their ligands. Annu Rev Biochem 76:141–165
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 141-165
-
-
Gay, N.J.1
Gangloff, M.2
-
14
-
-
0012929728
-
Toll-like receptors
-
COI: 1:CAS:528:DC%2BD3sXjtF2isrg%3D, PID: 12524386
-
Takeda K, Kaisho T, Akira S (2003) Toll-like receptors. Annu Rev Immunol 21:335–376
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, S.3
-
15
-
-
33646347356
-
Toll-like receptor signaling in the liver
-
COI: 1:CAS:528:DC%2BD28Xls1Wit7s%3D, PID: 16697751
-
Schwabe RF, Seki E, Brenner DA (2006) Toll-like receptor signaling in the liver. Gastroenterology 130:1886–1900
-
(2006)
Gastroenterology
, vol.130
, pp. 1886-1900
-
-
Schwabe, R.F.1
Seki, E.2
Brenner, D.A.3
-
16
-
-
47149105036
-
Toll-like receptors and adaptor molecules in liver disease: update
-
COI: 1:CAS:528:DC%2BD1cXptFemu7o%3D, PID: 18506843
-
Seki E, Brenner DA (2008) Toll-like receptors and adaptor molecules in liver disease: update. Hepatology 48:322–335
-
(2008)
Hepatology
, vol.48
, pp. 322-335
-
-
Seki, E.1
Brenner, D.A.2
-
17
-
-
34548656855
-
Signaling pathways downstream of pattern-recognition receptors and their cross talk
-
COI: 1:CAS:528:DC%2BD2sXhtVehtb%2FL, PID: 17328678
-
Lee MS, Kim YJ (2007) Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annu Rev Biochem 76:447–480
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 447-480
-
-
Lee, M.S.1
Kim, Y.J.2
-
18
-
-
3142724031
-
Toll-like receptor signalling
-
COI: 1:CAS:528:DC%2BD2cXlt1Cqur0%3D, PID: 15229469
-
Akira S, Takeda K (2004) Toll-like receptor signalling. Nat Rev Immunol 4:499–511
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
19
-
-
79952130140
-
Innate antiviral immune responses to hepatitis B virus
-
COI: 1:CAS:528:DC%2BC3cXoslGiur4%3D, PID: 21994686
-
Ait-Goughoulte M, Lucifora J, Zoulim F, Durantel D (2010) Innate antiviral immune responses to hepatitis B virus. Viruses 2:1394–1410
-
(2010)
Viruses
, vol.2
, pp. 1394-1410
-
-
Ait-Goughoulte, M.1
Lucifora, J.2
Zoulim, F.3
Durantel, D.4
-
20
-
-
80052365243
-
Role of Toll-like receptors in liver health and disease
-
COI: 1:CAS:528:DC%2BC3MXpsFOhsL8%3D
-
Broering R, Lu M, Schlaak JF (2011) Role of Toll-like receptors in liver health and disease. Clin Sci (Lond) 121:415–426
-
(2011)
Clin Sci (Lond)
, vol.121
, pp. 415-426
-
-
Broering, R.1
Lu, M.2
Schlaak, J.F.3
-
21
-
-
84869118771
-
The innate immune response to hepatitis B virus infection: implications for pathogenesis and therapy
-
COI: 1:CAS:528:DC%2BC38XhslCkt7jE, PID: 23072881
-
Chang J, Block TM, Guo JT (2012) The innate immune response to hepatitis B virus infection: implications for pathogenesis and therapy. Antivir Res 96:405–413
-
(2012)
Antivir Res
, vol.96
, pp. 405-413
-
-
Chang, J.1
Block, T.M.2
Guo, J.T.3
-
22
-
-
2342588229
-
Genomic analysis of the hostresponse to hepatitis B virus infection
-
COI: 1:CAS:528:DC%2BD2cXjvVyhsr8%3D, PID: 15100412
-
Wieland S, Thimme R, Purcell RH, Chisari FV (2004) Genomic analysis of the hostresponse to hepatitis B virus infection. Proc Natl Acad Sci U S A 101:6669–6674
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 6669-6674
-
-
Wieland, S.1
Thimme, R.2
Purcell, R.H.3
Chisari, F.V.4
-
23
-
-
0037180553
-
Genomic analysis of the host response to hepatitis C virus infection
-
Su AI, Pezacki JP, Wodicka L, Brideau AD, Supekova L, Thimme R, Wieland S, Bukh J, Purcell RH, Schultz PG, Chisari FV (2002) Genomic analysis of the host response to hepatitis C virus infection. Proc Natl Acad Sci U S A99:15669–15674
-
(2002)
Proc Natl Acad Sci U S
, vol.A99
, pp. 15669-15674
-
-
Su, A.I.1
Pezacki, J.P.2
Wodicka, L.3
Brideau, A.D.4
Supekova, L.5
Thimme, R.6
Wieland, S.7
Bukh, J.8
Purcell, R.H.9
Schultz, P.G.10
Chisari, F.V.11
-
24
-
-
70349435373
-
Temporal analysis of early immune responses in patients with acute hepatitis B virus infection
-
COI: 1:CAS:528:DC%2BD1MXht12gtr%2FJ, PID: 19591831
-
Dunn C, Peppa D, Khanna P, Nebbia G, Jones M, Brendish N, Lascar RM, Brown D, Gilson RJ, Tedder RJ, Dusheiko GM, Jacobs M, Klenerman P, Maini MK (2009) Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. Gastroenterology 137:1289–1300
-
(2009)
Gastroenterology
, vol.137
, pp. 1289-1300
-
-
Dunn, C.1
Peppa, D.2
Khanna, P.3
Nebbia, G.4
Jones, M.5
Brendish, N.6
Lascar, R.M.7
Brown, D.8
Gilson, R.J.9
Tedder, R.J.10
Dusheiko, G.M.11
Jacobs, M.12
Klenerman, P.13
Maini, M.K.14
-
25
-
-
73149094329
-
Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection
-
PID: 19937696
-
Hösel M, Quasdorff M, Wiegmann K, Webb D, Zedler U, Broxtermann M, Tedjokusumo R, Esser K, Arzberger S, Kirschning CJ, Langenkamp A, Falk C, Büning H, Rose-John S, Protzer U (2009) Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection. Hepatology 50:1773–1782
-
(2009)
Hepatology
, vol.50
, pp. 1773-1782
-
-
Hösel, M.1
Quasdorff, M.2
Wiegmann, K.3
Webb, D.4
Zedler, U.5
Broxtermann, M.6
Tedjokusumo, R.7
Esser, K.8
Arzberger, S.9
Kirschning, C.J.10
Langenkamp, A.11
Falk, C.12
Büning, H.13
Rose-John, S.14
Protzer, U.15
-
26
-
-
37749050365
-
Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice
-
COI: 1:CAS:528:DC%2BD2sXhsVGiur%2FN, PID: 17929296
-
Wu J, Lu M, Meng Z, Trippler M, Broering R, Szczeponek A, Krux F, Dittmer U, Roggendorf M, Gerken G, Schlaak JF (2007) Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice. Hepatology 46:1769–1778
-
(2007)
Hepatology
, vol.46
, pp. 1769-1778
-
-
Wu, J.1
Lu, M.2
Meng, Z.3
Trippler, M.4
Broering, R.5
Szczeponek, A.6
Krux, F.7
Dittmer, U.8
Roggendorf, M.9
Gerken, G.10
Schlaak, J.F.11
-
27
-
-
0033998463
-
Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice
-
COI: 1:CAS:528:DC%2BD3cXislGrurk%3D, PID: 10756029
-
Wieland SF, Guidotti LG, Chisari FV (2000) Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice. J Virol 74:4165–4173
-
(2000)
J Virol
, vol.74
, pp. 4165-4173
-
-
Wieland, S.F.1
Guidotti, L.G.2
Chisari, F.V.3
-
28
-
-
18744399291
-
Toll-like receptor signaling inhibits hepatitis B virus replication in vivo
-
COI: 1:CAS:528:DC%2BD2MXksFKgtr0%3D, PID: 15890966
-
Isogawa M, Robek MD, Furuichi Y, Chisari FV (2005) Toll-like receptor signaling inhibits hepatitis B virus replication in vivo. J Virol 79:7269–7272
-
(2005)
J Virol
, vol.79
, pp. 7269-7272
-
-
Isogawa, M.1
Robek, M.D.2
Furuichi, Y.3
Chisari, F.V.4
-
29
-
-
22244456417
-
Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids
-
COI: 1:CAS:528:DC%2BD2MXmsFaru7k%3D, PID: 15994231
-
Wieland SF, Eustaquio A, Whitten-Bauer C, Boyd B, Chisari FV (2005) Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids. Proc Natl Acad Sci U S A 102:9913–9917
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9913-9917
-
-
Wieland, S.F.1
Eustaquio, A.2
Whitten-Bauer, C.3
Boyd, B.4
Chisari, F.V.5
-
30
-
-
84909606393
-
Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways
-
COI: 1:CAS:528:DC%2BC2cXhvV2jt7rL, PID: 25206268
-
Pei R, Chen X, Lu M (2014) Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways. World J Gastroenterol 20:11618–11629
-
(2014)
World J Gastroenterol
, vol.20
, pp. 11618-11629
-
-
Pei, R.1
Chen, X.2
Lu, M.3
-
31
-
-
84896029673
-
Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA
-
COI: 1:CAS:528:DC%2BC2cXjvVygsrY%3D, PID: 24557838
-
Lucifora J, Xia Y, Reisinger F, Zhang K, Stadler D, Cheng X, Sprinzl MF, Koppensteiner H, Makowska Z, Volz T, Remouchamps C, Chou WM, Thasler WE, Durantel D, Hüser N, Liang TJ, Münk C, Heim MH, Browning JL, Dejardin E, Schindler M, Dandri M, Heikenwalder M, Protzer U (2014) Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA. Science 343:1221–1228
-
(2014)
Science
, vol.343
, pp. 1221-1228
-
-
Lucifora, J.1
Xia, Y.2
Reisinger, F.3
Zhang, K.4
Stadler, D.5
Cheng, X.6
Sprinzl, M.F.7
Koppensteiner, H.8
Makowska, Z.9
Volz, T.10
Remouchamps, C.11
Chou, W.M.12
Thasler, W.E.13
Durantel, D.14
Hüser, N.15
Liang, T.J.16
Münk, C.17
Heim, M.H.18
Browning, J.L.19
Dejardin, E.20
Schindler, M.21
Dandri, M.22
Heikenwalder, M.23
Protzer, U.24
more..
-
32
-
-
75949130109
-
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific
-
COI: 1:CAS:528:DC%2BC3cXisVKitr4%3D, PID: 19922426
-
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, Bucchi A, Krux F, Dittmer U, Yang D, Roggendorf M, Gerken G, Lu M, Schlaak JF (2010) Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology 129:363–374
-
(2010)
Immunology
, vol.129
, pp. 363-374
-
-
Wu, J.1
Meng, Z.2
Jiang, M.3
Zhang, E.4
Trippler, M.5
Broering, R.6
Bucchi, A.7
Krux, F.8
Dittmer, U.9
Yang, D.10
Roggendorf, M.11
Gerken, G.12
Lu, M.13
Schlaak, J.F.14
-
33
-
-
84910635824
-
Toll-like receptor-mediated immune responses are attenuated in the presence of high levels of hepatitis B virus surface antigen
-
Jiang M, Broering R, Trippler M, Poggenpohl L, Fiedler M, Gerken G, Lu M, Schlaak JF (2014) Toll-like receptor-mediated immune responses are attenuated in the presence of high levels of hepatitis B virus surface antigen. J Viral Hepat. doi:10.1111/jvh.12216
-
(2014)
J Viral Hepat
-
-
Jiang, M.1
Broering, R.2
Trippler, M.3
Poggenpohl, L.4
Fiedler, M.5
Gerken, G.6
Lu, M.7
Schlaak, J.F.8
-
34
-
-
0036097046
-
Cytokine-sensitive replication of hepatitis B virus in immortalized mouse hepatocyte cultures
-
COI: 1:CAS:528:DC%2BD38XjslGnurs%3D, PID: 11991993
-
Pasquetto V, Wieland SF, Uprichard SL, Tripodi M, Chisari FV (2002) Cytokine-sensitive replication of hepatitis B virus in immortalized mouse hepatocyte cultures. J Virol 76:5646–5653
-
(2002)
J Virol
, vol.76
, pp. 5646-5653
-
-
Pasquetto, V.1
Wieland, S.F.2
Uprichard, S.L.3
Tripodi, M.4
Chisari, F.V.5
-
35
-
-
65449117568
-
Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells
-
COI: 1:CAS:528:DC%2BD1MXkslSqu7s%3D, PID: 19140219
-
Wu J, Meng Z, Jiang M, Pei R, Trippler M, Broering R, Bucchi A, Sowa JP, Dittmer U, Yang D, Roggendorf M, Gerken G, Lu M, Schlaak JF (2009) Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells. Hepatology 49:1132–1140
-
(2009)
Hepatology
, vol.49
, pp. 1132-1140
-
-
Wu, J.1
Meng, Z.2
Jiang, M.3
Pei, R.4
Trippler, M.5
Broering, R.6
Bucchi, A.7
Sowa, J.P.8
Dittmer, U.9
Yang, D.10
Roggendorf, M.11
Gerken, G.12
Lu, M.13
Schlaak, J.F.14
-
36
-
-
84866371576
-
HBsAg inhibits IFN-α production in plasmacytoid dendritic cells through TNF-α and IL-10 induction in monocytes
-
COI: 1:CAS:528:DC%2BC38XhsVSjtbnP, PID: 23024774
-
Shi B, Ren G, Hu Y, Wang S, Zhang Z, Yuan Z (2012) HBsAg inhibits IFN-α production in plasmacytoid dendritic cells through TNF-α and IL-10 induction in monocytes. PLoS One 7:e44900
-
(2012)
PLoS One
, vol.7
, pp. e44900
-
-
Shi, B.1
Ren, G.2
Hu, Y.3
Wang, S.4
Zhang, Z.5
Yuan, Z.6
-
37
-
-
77955381494
-
Hepatitis B virus polymerase blocks pattern recognitionreceptor signaling via interaction with DDX3: implications for immune evasion
-
PID: 20657822
-
Wang H, Ryu WS (2010) Hepatitis B virus polymerase blocks pattern recognitionreceptor signaling via interaction with DDX3: implications for immune evasion. PLoS Pathog 6:e1000986
-
(2010)
PLoS Pathog
, vol.6
, pp. e1000986
-
-
Wang, H.1
Ryu, W.S.2
-
38
-
-
77955290279
-
Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3
-
COI: 1:CAS:528:DC%2BC3cXhtVCrsrfK, PID: 20375222
-
Yu S, Chen J, Wu M, Chen H, Kato N, Yuan Z (2010) Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3. J Gen Virol 91:2080–2090
-
(2010)
J Gen Virol
, vol.91
, pp. 2080-2090
-
-
Yu, S.1
Chen, J.2
Wu, M.3
Chen, H.4
Kato, N.5
Yuan, Z.6
-
39
-
-
36749058339
-
Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1
-
COI: 1:CAS:528:DC%2BD2sXhsVersLfL, PID: 18024894
-
Wu M, Xu Y, Lin S, Zhang X, Xiang L, Yuan Z (2007) Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1. J Gen Virol 88:3260–3269
-
(2007)
J Gen Virol
, vol.88
, pp. 3260-3269
-
-
Wu, M.1
Xu, Y.2
Lin, S.3
Zhang, X.4
Xiang, L.5
Yuan, Z.6
-
40
-
-
84873311551
-
Hepatitis B virus polymerase impairs interferon-α-induced STATs activation through inhibition of importin-α5 and protein kinase C-δ
-
COI: 1:CAS:528:DC%2BC3sXit1Wgtrw%3D, PID: 22996189
-
Chen J, Wu M, Zhang X, Zhang W, Zhang Z, Chen L, He J, Zheng Y, Chen C, Wang F, Hu Y, Zhou X, Wang C, Xu Y, Lu M, Yuan Z (2013) Hepatitis B virus polymerase impairs interferon-α-induced STATs activation through inhibition of importin-α5 and protein kinase C-δ. Hepatology 57:470–482
-
(2013)
Hepatology
, vol.57
, pp. 470-482
-
-
Chen, J.1
Wu, M.2
Zhang, X.3
Zhang, W.4
Zhang, Z.5
Chen, L.6
He, J.7
Zheng, Y.8
Chen, C.9
Wang, F.10
Hu, Y.11
Zhou, X.12
Wang, C.13
Xu, Y.14
Lu, M.15
Yuan, Z.16
-
41
-
-
78650645590
-
Hepatitis B virus regulatory HBx protein binds to adaptor protein IPS-1 and inhibits the activation of beta interferon
-
PID: 21068253
-
Kumar M, Jung SY, Hodgson AJ, Madden CR, Qin J, Slagle BL (2011) Hepatitis B virus regulatory HBx protein binds to adaptor protein IPS-1 and inhibits the activation of beta interferon. J Virol 85:987–995
-
(2011)
J Virol
, vol.85
, pp. 987-995
-
-
Kumar, M.1
Jung, S.Y.2
Hodgson, A.J.3
Madden, C.R.4
Qin, J.5
Slagle, B.L.6
-
42
-
-
77955496554
-
The hepatitis B virus X protein disrupts innate immunity by down regulating mitochondrial antiviral signaling protein
-
COI: 1:CAS:528:DC%2BC3cXotlymtLY%3D, PID: 20554965
-
Wei C, Ni C, Song T, Liu Y, Yang X, Zheng Z, Jia Y, Yuan Y, Guan K, Xu Y, Cheng X, Zhang Y, Yang X, Wang Y, Wen C, Wu Q, Shi W, Zhong H (2010) The hepatitis B virus X protein disrupts innate immunity by down regulating mitochondrial antiviral signaling protein. J Immunol 185:1158–1168
-
(2010)
J Immunol
, vol.185
, pp. 1158-1168
-
-
Wei, C.1
Ni, C.2
Song, T.3
Liu, Y.4
Yang, X.5
Zheng, Z.6
Jia, Y.7
Yuan, Y.8
Guan, K.9
Xu, Y.10
Cheng, X.11
Zhang, Y.12
Yang, X.13
Wang, Y.14
Wen, C.15
Wu, Q.16
Shi, W.17
Zhong, H.18
-
43
-
-
84892707497
-
Reduced Toll-like receptor 3 expression in chronic hepatitis B patients and its restoration by interferon therapy
-
COI: 1:CAS:528:DC%2BC2cXltFWgtbs%3D, PID: 23744559
-
Huang YW, Lin SC, Wei SC, Hu JT, Chang HY, Huang SH, Chen DS, Chen PJ, Hsu PN, Yang SS, Kao JH (2013) Reduced Toll-like receptor 3 expression in chronic hepatitis B patients and its restoration by interferon therapy. Antivir Ther 18:877–884
-
(2013)
Antivir Ther
, vol.18
, pp. 877-884
-
-
Huang, Y.W.1
Lin, S.C.2
Wei, S.C.3
Hu, J.T.4
Chang, H.Y.5
Huang, S.H.6
Chen, D.S.7
Chen, P.J.8
Hsu, P.N.9
Yang, S.S.10
Kao, J.H.11
-
44
-
-
38949147078
-
Molecular characterization of woodchuck type I interferons and their expression by woodchuck peripheral blood lymphocytes
-
COI: 1:CAS:528:DC%2BD1cXhsl2gtrc%3D, PID: 18096400
-
Lu Y, Xu Y, Yang D, Kemper T, Roggendorf M, Lu M (2008) Molecular characterization of woodchuck type I interferons and their expression by woodchuck peripheral blood lymphocytes. Cytokine 41:127–135
-
(2008)
Cytokine
, vol.41
, pp. 127-135
-
-
Lu, Y.1
Xu, Y.2
Yang, D.3
Kemper, T.4
Roggendorf, M.5
Lu, M.6
-
45
-
-
72049087654
-
Lipopolysaccharide-induced innate immune responses in primary hepatocytes downregulates woodchuck hepatitis virus replication via interferon-independent pathways
-
COI: 1:CAS:528:DC%2BD1MXhtlOisLzJ, PID: 19573162
-
Zhang X, Meng Z, Qiu S, Xu Y, Yang D, Schlaak JF, Roggendorf M, Lu M (2009) Lipopolysaccharide-induced innate immune responses in primary hepatocytes downregulates woodchuck hepatitis virus replication via interferon-independent pathways. Cell Microbiol 11:1624–1637
-
(2009)
Cell Microbiol
, vol.11
, pp. 1624-1637
-
-
Zhang, X.1
Meng, Z.2
Qiu, S.3
Xu, Y.4
Yang, D.5
Schlaak, J.F.6
Roggendorf, M.7
Lu, M.8
-
46
-
-
70350134352
-
Stimulation of the interleukin-1 receptor and Toll-like receptor 2 inhibits hepatitis B virus replication in hepatoma cell lines in vitro
-
COI: 1:CAS:528:DC%2BD1MXhtlOrtrjK, PID: 19812442
-
Thompson AJ, Colledge D, Rodgers S, Wilson R, Revill P, Desmond P, Mansell A, Visvanathan K, Locarnini S (2009) Stimulation of the interleukin-1 receptor and Toll-like receptor 2 inhibits hepatitis B virus replication in hepatoma cell lines in vitro. Antivir Ther 14:797–808
-
(2009)
Antivir Ther
, vol.14
, pp. 797-808
-
-
Thompson, A.J.1
Colledge, D.2
Rodgers, S.3
Wilson, R.4
Revill, P.5
Desmond, P.6
Mansell, A.7
Visvanathan, K.8
Locarnini, S.9
-
47
-
-
84865153815
-
Role of Toll-like receptor 2 in the immune response against hepadnaviral infection
-
PID: 22617154
-
Zhang X, Ma Z, Liu H, Liu J, Meng Z, Broering R, Yang D, Schlaak JF, Roggendorf M, Lu M (2012) Role of Toll-like receptor 2 in the immune response against hepadnaviral infection. J Hepatol 57:522–528
-
(2012)
J Hepatol
, vol.57
, pp. 522-528
-
-
Zhang, X.1
Ma, Z.2
Liu, H.3
Liu, J.4
Meng, Z.5
Broering, R.6
Yang, D.7
Schlaak, J.F.8
Roggendorf, M.9
Lu, M.10
-
48
-
-
56549095016
-
Characterization of the innate immune signalling pathways in hepatocyte cell lines
-
COI: 1:STN:280:DC%2BD1M%2FhsFOjsw%3D%3D, PID: 18673429
-
Preiss S, Thompson A, Chen X, Rodgers S, Markovska V, Desmond P, Visvanathan K, Li K, Locarnini S, Revill P (2008) Characterization of the innate immune signalling pathways in hepatocyte cell lines. J Viral Hepat 15:888–900
-
(2008)
J Viral Hepat
, vol.15
, pp. 888-900
-
-
Preiss, S.1
Thompson, A.2
Chen, X.3
Rodgers, S.4
Markovska, V.5
Desmond, P.6
Visvanathan, K.7
Li, K.8
Locarnini, S.9
Revill, P.10
-
49
-
-
79960090844
-
Suppression of hepatitis B virus replication in Tupaia hepatocytes by tumor necrosis factor alpha of Tupaia belangeri
-
PID: 21684599
-
Xu Y, Kock J, Lu Y, Yang D, Lu M, Zhao X (2011) Suppression of hepatitis B virus replication in Tupaia hepatocytes by tumor necrosis factor alpha of Tupaia belangeri. Comp Immunol Microbiol Infect Dis 34:361–368
-
(2011)
Comp Immunol Microbiol Infect Dis
, vol.34
, pp. 361-368
-
-
Xu, Y.1
Kock, J.2
Lu, Y.3
Yang, D.4
Lu, M.5
Zhao, X.6
-
50
-
-
33846492518
-
Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein
-
COI: 1:CAS:528:DC%2BD2sXht1arsbk%3D, PID: 17187404
-
Visvanathan K, Skinner NA, Thompson AJ, Riordan SM, Sozzi V, Edwards R, Rodgers S, Kurtovic J, Chang J, Lewin S, Desmond P, Locarnini S (2007) Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein. Hepatology 45:102–110
-
(2007)
Hepatology
, vol.45
, pp. 102-110
-
-
Visvanathan, K.1
Skinner, N.A.2
Thompson, A.J.3
Riordan, S.M.4
Sozzi, V.5
Edwards, R.6
Rodgers, S.7
Kurtovic, J.8
Chang, J.9
Lewin, S.10
Desmond, P.11
Locarnini, S.12
-
51
-
-
80052444371
-
The hepatitis B e antigen (HBeAg) targets and suppresses activation of the toll-like receptor signaling pathway
-
COI: 1:CAS:528:DC%2BC3MXhtF2hurnN, PID: 21334391
-
Lang T, Lo C, Skinner N, Locarnini S, Visvanathan K, Mansell A (2011) The hepatitis B e antigen (HBeAg) targets and suppresses activation of the toll-like receptor signaling pathway. J Hepatol 55:762–769
-
(2011)
J Hepatol
, vol.55
, pp. 762-769
-
-
Lang, T.1
Lo, C.2
Skinner, N.3
Locarnini, S.4
Visvanathan, K.5
Mansell, A.6
-
52
-
-
49149128080
-
Expression profiles and function of Toll-like receptors 2 and 4 in peripheral blood mononuclear cells of chronic hepatitis B patients
-
COI: 1:CAS:528:DC%2BD1cXhtVShtr3K, PID: 18565796
-
Chen Z, Cheng Y, Xu Y, Liao J, Zhang X, Hu Y, Zhang Q, Wang J, Zhang Z, Shen F, Yuan Z (2008) Expression profiles and function of Toll-like receptors 2 and 4 in peripheral blood mononuclear cells of chronic hepatitis B patients. Clin Immunol 128:400–408
-
(2008)
Clin Immunol
, vol.128
, pp. 400-408
-
-
Chen, Z.1
Cheng, Y.2
Xu, Y.3
Liao, J.4
Zhang, X.5
Hu, Y.6
Zhang, Q.7
Wang, J.8
Zhang, Z.9
Shen, F.10
Yuan, Z.11
-
53
-
-
84875809649
-
Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity
-
PID: 23499443
-
Böttcher JP, Schanz O, Wohlleber D, Abdullah Z, Debey-Pascher S, Staratschek-Jox A, Höchst B, Hegenbarth S, Grell J, Limmer A, Atreya I, Neurath MF, Busch DH, Schmitt E, van Endert P, Kolanus W, Kurts C, Schultze JL, Diehl L, Knolle PA (2013) Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity. Cell Rep 3:779–795
-
(2013)
Cell Rep
, vol.3
, pp. 779-795
-
-
Böttcher, J.P.1
Schanz, O.2
Wohlleber, D.3
Abdullah, Z.4
Debey-Pascher, S.5
Staratschek-Jox, A.6
Höchst, B.7
Hegenbarth, S.8
Grell, J.9
Limmer, A.10
Atreya, I.11
Neurath, M.F.12
Busch, D.H.13
Schmitt, E.14
van Endert, P.15
Kolanus, W.16
Kurts, C.17
Schultze, J.L.18
Diehl, L.19
Knolle, P.A.20
more..
-
54
-
-
72249119475
-
Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity
-
COI: 1:CAS:528:DC%2BC3cXht1ajt7w%3D, PID: 19737567
-
Kern M, Popov A, Scholz K, Schumak B, Djandji D, Limmer A, Eggle D, Sacher T, Zawatzky R, Holtappels R, Reddehase MJ, Hartmann G, Debey-Pascher S, Diehl L, Kalinke U, Koszinowski U, Schultze J, Knolle PA (2010) Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity. Gastroenterology 138:336–346
-
(2010)
Gastroenterology
, vol.138
, pp. 336-346
-
-
Kern, M.1
Popov, A.2
Scholz, K.3
Schumak, B.4
Djandji, D.5
Limmer, A.6
Eggle, D.7
Sacher, T.8
Zawatzky, R.9
Holtappels, R.10
Reddehase, M.J.11
Hartmann, G.12
Debey-Pascher, S.13
Diehl, L.14
Kalinke, U.15
Koszinowski, U.16
Schultze, J.17
Knolle, P.A.18
-
55
-
-
84890385207
-
TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro
-
COI: 1:CAS:528:DC%2BC3sXhvV2lsLfN, PID: 24227786
-
Liu J, Jiang M, Ma Z, Dietze KK, Zelinskyy G, Yang D, Dittmer U, Schlaak JF, Roggendorf M, Lu M (2013) TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro. J Immunol 191:6178–6190
-
(2013)
J Immunol
, vol.191
, pp. 6178-6190
-
-
Liu, J.1
Jiang, M.2
Ma, Z.3
Dietze, K.K.4
Zelinskyy, G.5
Yang, D.6
Dittmer, U.7
Schlaak, J.F.8
Roggendorf, M.9
Lu, M.10
-
56
-
-
84877820210
-
Hepatitis B virus surface antigen selectively inhibits TLR2 ligand-induced IL-12 production in monocytes/macrophages by interfering with JNK activation
-
COI: 1:CAS:528:DC%2BC3sXmvFyqt7k%3D, PID: 23585678
-
Wang S, Chen Z, Hu C, Qian F, Cheng Y, Wu M, Shi B, Chen J, Hu Y, Yuan Z (2013) Hepatitis B virus surface antigen selectively inhibits TLR2 ligand-induced IL-12 production in monocytes/macrophages by interfering with JNK activation. J Immunol 190:5142–5151
-
(2013)
J Immunol
, vol.190
, pp. 5142-5151
-
-
Wang, S.1
Chen, Z.2
Hu, C.3
Qian, F.4
Cheng, Y.5
Wu, M.6
Shi, B.7
Chen, J.8
Hu, Y.9
Yuan, Z.10
-
57
-
-
84862851678
-
Preclinical development of TLR ligands as drugs for the treatment of chronic viral infection
-
Zhang X, Kraft A, Boering R, Schlaak JF, Dittmer U, Lu M (2012) Preclinical development of TLR ligands as drugs for the treatment of chronic viral infection. Expert Opin Drug Discov 7:561–597
-
(2012)
Expert Opin Drug Discov
, vol.7
, pp. 561-597
-
-
Zhang, X.1
Kraft, A.2
Boering, R.3
Schlaak, J.F.4
Dittmer, U.5
Lu, M.6
-
58
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
COI: 1:CAS:528:DC%2BD38XjtlWgtbw%3D, PID: 11861616
-
Krieg AM (2002) CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 20:709–760
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
59
-
-
9144238063
-
Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
-
COI: 1:CAS:528:DC%2BD2cXnslymtA%3D%3D, PID: 14971051
-
Vollmer J, Weeratna R, Payette P, Jurk M, Schetter C, Laucht M, Wader T, Tluk S, Liu M, Davis HL, Krieg AM (2004) Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities. Eur J Immunol 34:251–262
-
(2004)
Eur J Immunol
, vol.34
, pp. 251-262
-
-
Vollmer, J.1
Weeratna, R.2
Payette, P.3
Jurk, M.4
Schetter, C.5
Laucht, M.6
Wader, T.7
Tluk, S.8
Liu, M.9
Davis, H.L.10
Krieg, A.M.11
-
60
-
-
81355129949
-
Anti-viral efficacy and induction of an antibody response against surface antigen with the TLR7 Agonist GS-9620 in the Woodchuck Model of Chronic HBV Infection
-
Menne S, Tennant BC, Liu KH, Ascenzi MA, Baldwin BH, Bellezza CA, Cote PJ, Zheng X, Wolfgang G, Turnas D (2011) Anti-viral efficacy and induction of an antibody response against surface antigen with the TLR7 Agonist GS-9620 in the Woodchuck Model of Chronic HBV Infection. J Hepatol 54:S441
-
(2011)
J Hepatol
, vol.54
, pp. S441
-
-
Menne, S.1
Tennant, B.C.2
Liu, K.H.3
Ascenzi, M.A.4
Baldwin, B.H.5
Bellezza, C.A.6
Cote, P.J.7
Zheng, X.8
Wolfgang, G.9
Turnas, D.10
-
61
-
-
84862896269
-
Therapeutic efficacy of a TLR7 agonist for HBV chronic infection in chimpanzees
-
Lanford RE, Guerra B, Chavez DC, Hodara VL, Zheng X, Wolfgang G, Tumas D (2011) Therapeutic efficacy of a TLR7 agonist for HBV chronic infection in chimpanzees. J Hepatol 54:S45
-
(2011)
J Hepatol
, vol.54
, pp. S45
-
-
Lanford, R.E.1
Guerra, B.2
Chavez, D.C.3
Hodara, V.L.4
Zheng, X.5
Wolfgang, G.6
Tumas, D.7
-
62
-
-
33845786018
-
Current and future drugs targeting one class of innate immunity receptors: the Toll-like receptors
-
COI: 1:CAS:528:DC%2BD2sXhsFOjtw%3D%3D, PID: 17198976
-
Romagne F (2007) Current and future drugs targeting one class of innate immunity receptors: the Toll-like receptors. Drug Discov Today 12:80–87
-
(2007)
Drug Discov Today
, vol.12
, pp. 80-87
-
-
Romagne, F.1
-
63
-
-
0037654784
-
Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi. 529
-
COI: 1:CAS:528:DC%2BD3sXjsVOksL0%3D, PID: 12899573
-
Evans JT, Cluff CW, Johnson DA, Lacy MJ, Persing DH, Baldridge JR (2003) Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi. 529. Expert Rev Vaccines 2:219–229
-
(2003)
Expert Rev Vaccines
, vol.2
, pp. 219-229
-
-
Evans, J.T.1
Cluff, C.W.2
Johnson, D.A.3
Lacy, M.J.4
Persing, D.H.5
Baldridge, J.R.6
-
64
-
-
33845366891
-
A controlled clinical trial comparing the safety and immunogenicity of a new adjuvanted hepatitis B vaccine with a standard hepatitis B vaccine
-
COI: 1:CAS:528:DC%2BD28Xht1Shu7%2FI, PID: 16884836
-
Dupont J, Altclas J, Lepetic A, Lombardo M, Vázquez V, Salgueira C, Seigelchifer M, Arndtz N, Antunez E, von Eschen K, Janowicz Z (2006) A controlled clinical trial comparing the safety and immunogenicity of a new adjuvanted hepatitis B vaccine with a standard hepatitis B vaccine. Vaccine 24:7167–7174
-
(2006)
Vaccine
, vol.24
, pp. 7167-7174
-
-
Dupont, J.1
Altclas, J.2
Lepetic, A.3
Lombardo, M.4
Vázquez, V.5
Salgueira, C.6
Seigelchifer, M.7
Arndtz, N.8
Antunez, E.9
von Eschen, K.10
Janowicz, Z.11
-
65
-
-
34249677845
-
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
-
COI: 1:CAS:528:DC%2BD2sXkvVOgsrs%3D, PID: 17479101
-
Kanzler H, Barrat FJ, Hessel EM, Coffman RL (2007) Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med 13:552–559
-
(2007)
Nat Med
, vol.13
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
Coffman, R.L.4
-
66
-
-
84862785552
-
Demonstration of safety and enhanced seroprotection against hepatitis B with investigational HBsAg-1018 ISS vaccine compared to a licensed hepatitis B vaccine
-
COI: 1:CAS:528:DC%2BC38Xjs1altrY%3D, PID: 22342916
-
Sablan BP, Kim DJ, Barzaga NG, Chow WC, Cho M, Ahn SH, Hwang SG, Lee JH, Namini H, Heyward WL (2012) Demonstration of safety and enhanced seroprotection against hepatitis B with investigational HBsAg-1018 ISS vaccine compared to a licensed hepatitis B vaccine. Vaccine 30:2689–2696
-
(2012)
Vaccine
, vol.30
, pp. 2689-2696
-
-
Sablan, B.P.1
Kim, D.J.2
Barzaga, N.G.3
Chow, W.C.4
Cho, M.5
Ahn, S.H.6
Hwang, S.G.7
Lee, J.H.8
Namini, H.9
Heyward, W.L.10
-
67
-
-
79955088827
-
Hepatitis B surface antigen-1018 ISS adjuvant-containing vaccine: a review of HEPLISAV safety and efficacy
-
COI: 1:CAS:528:DC%2BC3MXkvF2itbw%3D, PID: 21506639
-
Cooper C, Mackie D (2011) Hepatitis B surface antigen-1018 ISS adjuvant-containing vaccine: a review of HEPLISAV safety and efficacy. Expert Rev Vaccines 10:417–427
-
(2011)
Expert Rev Vaccines
, vol.10
, pp. 417-427
-
-
Cooper, C.1
Mackie, D.2
-
68
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
COI: 1:CAS:528:DC%2BC3cXktlWkuw%3D%3D, PID: 20075244
-
Iwasaki A, Medzhitov R (2010) Regulation of adaptive immunity by the innate immune system. Science 327:291–295
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
69
-
-
84906337676
-
Polyinosinic-polycytidylic acid (polyIC) treatment leads to the interferon-dependent clearance of hepatitis B virus in hydrodynamic injection mouse mode
-
COI: 1:CAS:528:DC%2BC2cXhs1yktrjF, PID: 24920792
-
Wu J, Chen M, Lin Y, Xia Y, Sun C, Wang J, Guo Y, Song J, Zhang E, Wang B, Zhen X, Schlaak JF, Lu M, Yang D (2014) Polyinosinic-polycytidylic acid (polyIC) treatment leads to the interferon-dependent clearance of hepatitis B virus in hydrodynamic injection mouse mode. J Virol 88:10421–10431
-
(2014)
J Virol
, vol.88
, pp. 10421-10431
-
-
Wu, J.1
Chen, M.2
Lin, Y.3
Xia, Y.4
Sun, C.5
Wang, J.6
Guo, Y.7
Song, J.8
Zhang, E.9
Wang, B.10
Zhen, X.11
Schlaak, J.F.12
Lu, M.13
Yang, D.14
-
70
-
-
33746256898
-
TLR2 engagement on CD8 T cells lowers the threshold for optimal antigen-induced T cell activation
-
COI: 1:CAS:528:DC%2BD28XnslOnurk%3D, PID: 16761317
-
Cottalorda A, Verschelde C, Marcais A, Tomkowiak M, Musette P, Uematsu S, Akira S, Marvel J, Bonnefoy-Berard N (2006) TLR2 engagement on CD8 T cells lowers the threshold for optimal antigen-induced T cell activation. Eur J Immunol 36:1684–1693
-
(2006)
Eur J Immunol
, vol.36
, pp. 1684-1693
-
-
Cottalorda, A.1
Verschelde, C.2
Marcais, A.3
Tomkowiak, M.4
Musette, P.5
Uematsu, S.6
Akira, S.7
Marvel, J.8
Bonnefoy-Berard, N.9
-
71
-
-
78149353783
-
When Toll-like receptor and T-cell receptor signals collide: a mechanism for enhanced CD8 T-cell effector function
-
COI: 1:CAS:528:DC%2BC3cXhsVKksb7O, PID: 20696947
-
Geng D, Zheng L, Srivastava R, Asprodites N, Velasco-Gonzalez C, Davila E (2010) When Toll-like receptor and T-cell receptor signals collide: a mechanism for enhanced CD8 T-cell effector function. Blood 116:3494–3504
-
(2010)
Blood
, vol.116
, pp. 3494-3504
-
-
Geng, D.1
Zheng, L.2
Srivastava, R.3
Asprodites, N.4
Velasco-Gonzalez, C.5
Davila, E.6
-
72
-
-
1542297739
-
TLR2 is expressed on activated T cells as a costimulatory receptor
-
COI: 1:CAS:528:DC%2BD2cXitlWhtrg%3D, PID: 14981245
-
Komai-Koma M, Jones L, Ogg GS, Xu D, Liew FY (2004) TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci U S A 101:3029–3034
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3029-3034
-
-
Komai-Koma, M.1
Jones, L.2
Ogg, G.S.3
Xu, D.4
Liew, F.Y.5
-
73
-
-
61449121028
-
TLR2 engagement on CD8 T cells enables generation of functional memory cells in response to a suboptimal TCR signal
-
COI: 1:CAS:528:DC%2BD1MXhsFKktLY%3D, PID: 19201838
-
Mercier BC, Cottalorda A, Coupet CA, Marvel J, Bonnefoy-Berard N (2009) TLR2 engagement on CD8 T cells enables generation of functional memory cells in response to a suboptimal TCR signal. J Immunol 182:1860–1867
-
(2009)
J Immunol
, vol.182
, pp. 1860-1867
-
-
Mercier, B.C.1
Cottalorda, A.2
Coupet, C.A.3
Marvel, J.4
Bonnefoy-Berard, N.5
-
74
-
-
54049096321
-
Engagement of Toll-like receptor-2 on cytotoxic T-lymphocytes occurs in vivo and augments antitumor activity
-
COI: 1:CAS:528:DC%2BD1cXht1SqsrfM, PID: 18587008
-
Asprodites N, Zheng L, Geng D, Velasco-Gonzalez C, Sanchez-Perez L, Davila E (2008) Engagement of Toll-like receptor-2 on cytotoxic T-lymphocytes occurs in vivo and augments antitumor activity. FASEB J 22:3628–3637
-
(2008)
FASEB J
, vol.22
, pp. 3628-3637
-
-
Asprodites, N.1
Zheng, L.2
Geng, D.3
Velasco-Gonzalez, C.4
Sanchez-Perez, L.5
Davila, E.6
-
75
-
-
77957361069
-
Amplifying TLR-MyD88 signals within tumor-specific T cells enhances antitumor activity to suboptimal levels of weakly immunogenic tumor antigens
-
COI: 1:CAS:528:DC%2BC3cXht1akt7rF, PID: 20807806
-
Geng D, Zheng L, Srivastava R, Velasco-Gonzalez C, Riker A, Markovic SN, Davila E (2010) Amplifying TLR-MyD88 signals within tumor-specific T cells enhances antitumor activity to suboptimal levels of weakly immunogenic tumor antigens. Cancer Res 70:7442–7454
-
(2010)
Cancer Res
, vol.70
, pp. 7442-7454
-
-
Geng, D.1
Zheng, L.2
Srivastava, R.3
Velasco-Gonzalez, C.4
Riker, A.5
Markovic, S.N.6
Davila, E.7
-
76
-
-
0024389666
-
In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine
-
COI: 1:CAS:528:DyaK3cXps1Giuw%3D%3D, PID: 2586628
-
Deres K, Schild H, Wiesmüller KH, Jung G, Rammensee HG (1989) In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine. Nature 342:561–564
-
(1989)
Nature
, vol.342
, pp. 561-564
-
-
Deres, K.1
Schild, H.2
Wiesmüller, K.H.3
Jung, G.4
Rammensee, H.G.5
-
77
-
-
0032769963
-
A pilot study of the CY-1899 T-cell vaccine in subjects chronically infected with hepatitis B virus. The CY1899 T Cell Vaccine Study Group
-
COI: 1:CAS:528:DyaK1MXlt1ajsLw%3D, PID: 10421664
-
Heathcote J, McHutchison J, Lee S, Tong M, Benner K, Minuk G, Wright T, Fikes J, Livingston B, Sette A, Chestnut R (1999) A pilot study of the CY-1899 T-cell vaccine in subjects chronically infected with hepatitis B virus. The CY1899 T Cell Vaccine Study Group. Hepatology 30:531–536
-
(1999)
Hepatology
, vol.30
, pp. 531-536
-
-
Heathcote, J.1
McHutchison, J.2
Lee, S.3
Tong, M.4
Benner, K.5
Minuk, G.6
Wright, T.7
Fikes, J.8
Livingston, B.9
Sette, A.10
Chestnut, R.11
-
78
-
-
7444271904
-
A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses
-
COI: 1:CAS:528:DC%2BD2cXhtVKhsbvP, PID: 15489266
-
Jackson DC, Lau YF, Le T, Suhrbier A, Deliyannis G, Cheers C, Smith C, Zeng W, Brown LE (2004) A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses. Proc Natl Acad Sci U S A 101:15440–15445
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 15440-15445
-
-
Jackson, D.C.1
Lau, Y.F.2
Le, T.3
Suhrbier, A.4
Deliyannis, G.5
Cheers, C.6
Smith, C.7
Zeng, W.8
Brown, L.E.9
-
79
-
-
0028876917
-
Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans
-
COI: 1:CAS:528:DyaK2MXivFyksro%3D, PID: 7814635
-
Vitiello A, Ishioka G, Grey HM, Rose R, Farness P, LaFond R, Yuan L, Chisari FV, Furze J, Bartholomeuz R et al (1995) Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans. J Clin Invest 95:341–349
-
(1995)
J Clin Invest
, vol.95
, pp. 341-349
-
-
Vitiello, A.1
Ishioka, G.2
Grey, H.M.3
Rose, R.4
Farness, P.5
LaFond, R.6
Yuan, L.7
Chisari, F.V.8
Furze, J.9
Bartholomeuz, R.10
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