Clinical and radiological findings in methadone-induced delayed leukoencephalopathy

Journal of Rehabilitation Medicine

Volumn 46, Issue 8, 2014, Pages 828-830

  Bileviciute Ljungar, Indre ^a   Häglund, Vera ^a   Carlsson, Jenny ^a   Von Heijne, Anders ^a  

^a DANDERYD HOSPITAL   (Sweden)

Author keywords

Baclofen; Demyelination; Methadone induced delayed leukoencephalopathy; Rehabilitation outcomes; Sertraline

Indexed keywords

METHADONE;

ADULT; BRAIN; CHEMICALLY INDUCED; CLINICAL TRIAL; COMPLICATION; COMPUTER ASSISTED TOMOGRAPHY; DAILY LIFE ACTIVITY; DRUG EFFECTS; DRUG OVERDOSE; ELECTROENCEPHALOGRAPHY; HOSPITAL PATIENT; HUMAN; LEUKOENCEPHALOPATHIES; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; REHABILITATION CENTER;

ACTIVITIES OF DAILY LIVING; ADULT; BRAIN; DRUG OVERDOSE; ELECTROENCEPHALOGRAPHY; HUMANS; INPATIENTS; LEUKOENCEPHALOPATHIES; MAGNETIC RESONANCE IMAGING; MALE; METHADONE; NEUROIMAGING; REHABILITATION CENTERS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84921961668     PISSN: 16501977     EISSN: 16512081     Source Type: Journal    
DOI: 10.2340/16501977-1820     Document Type: Article

References (10)

1. Shprecher D, Mehta L. The syndrome of delayed post-hypoxic leukoencephalopathy. Neurorehabilitation 2010; 26: 65-72.
2. Cerase A, Leonini S, Bellini M, Chianese G, Venturi C. Methadoneinduced toxic leukoencephalopathy: Diagnosis and follow-up by magnetic resonance imaging including diffusion-weighted imaging and apparent diffusion coefficient maps. J Neuroimaging 2011; 21: 283-286.
3. Mittal M, Wang Y, Reeves A, Newell K. Methadone-induced delayed posthypoxic encephalopathy: Clinical, radiological, and pathological findings. Case Report Med 2010; 2010: 716494.
4. Salgado R, Jorens P, Baar I, Cras P, Hans G, Parizel P. Methadoneinduced toxic leukoencephalopathy: MR imaging and MR proton spectroscopy findings. Am J Neuroradiol 2010; 31: 565-566.
5. Shprecher D, Flanigan K, Smith A, Smith S, Schenkenberg T, Steffens J. Clinical and diagnostic features of delayed hypoxic leukoencephalopathy. J Neuropsychiatry Clin Neurosci 2008; 20: 473-477.
6. Carroll I, Heritier Barras A-C, Dirren E, Burkhard PR, Horvath J. Delayed leukoencephalopathy after alprazolam and methadone overdose: A case report and review of the literature. Clin Neurol Neurosurg 2012; 114: 816-819.
7. Rekand T. Clinical assessment and management of spasticity: A review. Acta Neurol Scand 2010; 122: 62-66.
8. Chu D, Albin R, Young A, Penney J. Distribution and kinetics of GABAB binding sites in rat central nervous system: A quantitative autoradiographic study. Neuroscience 1990; 34: 341-357.
9. Duthey B, Hubner A, Diehl S, Boehncke D, Pfeffer J, Boehncke W-H. Anti-inflammatory effects of the GABAB receptor agonist baclofen in allergic contact dermatitis. Exp Dermatol 2010; 19: 661-666.
10. Filley CM, Kleinschmidt-DeMasters BK. Toxic leukoencephalopathy. N Engl J Med 2001; 345: 425-432.