Methadone-induced toxic leukoencephalopathy: MR imaging and MR proton spectroscopy findings

American Journal of Neuroradiology

Volumn 31, Issue 3, 2010, Pages 565-566

  Salgado, Rodrigo A ^a   Jorens, P G ^a   Baar, I ^a   Cras, P ^a   Hans, G ^a   Parizel, P M ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

METHADONE;

AGED; APATHY; ARM; ARTICLE; BABINSKI REFLEX; BLOOD ANALYSIS; CASE REPORT; CATATONIA; CHRONIC PAIN; DRUG INDUCED DISEASE; FEMALE; HEMISPHERE; HIP PROSTHESIS; HUMAN; INTRACTABLE PAIN; LEUKOENCEPHALOPATHY; MAGNETIC RESONANCE PROTON SPECTROSCOPY; NERVE STIMULATION; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGICAL REFLEX; RIGIDITY; URINALYSIS;

AGED; ANALGESICS, OPIOID; ASPARTIC ACID; CHOLINE; CREATINE; FEMALE; HUMANS; LEUKOENCEPHALOPATHIES; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; METHADONE; PROTONS;

EID: 77949506167     PISSN: 01956108     EISSN: None     Source Type: Journal    
DOI: 10.3174/ajnr.A1889     Document Type: Article

References (13)

1. Wolff K. Characterization of methadone overdose: clinical considerations and the scientific evidence. Ther Drug Monit 2002;24:457-70
2. Chen CY, Lee KW, Lee CC, et al. Heroin-induced spongiform leukoencephalopathy: value of diffusion MR imaging. J Comput Assist Tomogr 2000;24:735-37
3. Gacouin A, Lavoue S, Signouret T, et al. Reversible spongiform leucoencephalopathy after inhalation of heated heroin. Intensive Care Med 2003;29:1012-15. Epub 2003 Mar 14
4. Keogh CF, Andrews GT, Spacey SD, et al. Neuroimaging features of heroin inhalation toxicity: "chasing the dragon." AJR Am J Roentgenol 2003;180:847-50
5. Kriegstein AR, Shungu DC, Millar WS, et al. Leukoencephalopathy and raised brain lactate from heroin vapor inhalation ("chasing the dragon"). Neurology 1999;53:1765-73
6. Offiah C, Hall E. Heroin-induced leukoencephalopathy: characterization using MRI, diffusion-weighted imaging, and MR spectroscopy. Clin Radiol 2008;63:146-52
7. Chang WC, Lo CP, Kao HW, et al. MRI features of spongiform leukoencephalopathy following heroin inhalation. Neurology 2006;67:504
8. Anselmo M, Campos Rainho A, do Carmo Vale M, et al. Methadone intoxication in a child: toxic encephalopathy? J Child Neurol 2006;21:618-20
9. Riascos R, Kumfa P, Rojas R, et al. Fatal methadone intoxication in a child. Emerg Radiol 2008;15:67-70
10. Mills F, MacLennan SC, Devile CJ, et al. Severe cerebellitis following methadone poisoning. Pediatr Radiol 2008;38:227-29
11. Wolters EC, van Wijngaarden GK, Stam FC, et al. Leucoencephalopathy after inhaling "heroin" pyrolysate. Lancet 1982;2:1233-37
12. Nanan R, von Stockhausen HB, Petersen B, et al. Unusual pattern of leukoencephalopathy after morphine sulphate intoxication. Neuroradiology 2000;42:845-48
13. Vella S, Kreis R, Lovblad KO, et al. Acute leukoencephalopathy after inhalation of a single dose of heroin. Neuropediatrics 2003;34:100-04