The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets

RNA Biology

Volumn 11, Issue 10, 2014, Pages 1250-1261

  Scheiba, Rafael M ^a   De Opakua, Alain Ibáñez ^b   Díaz Quintana, Antonio ^a   Cruz Gallardo, Isabel ^a   Martínez Cruz, Luis A ^b   Martínez Chantar, María L ^b,c   Blanco, Francisco J ^b,d   Díaz Moreno, Irene ^a  

^a Universidad de Sevilla CSIC   (Spain)

^b CIC BIOGUNE   (Spain)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^d BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

Dimerization; Human antigen R (hur); Nuclear magnetic resonance (NMR); RNA binding; RNA binding protein (RBP); RNA recognition motif (RRM); Serine phosphorylation

Indexed keywords

HUR PROTEIN; HU ANTIGEN; PROTEIN BINDING; RNA; RNA BINDING PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DIMERIZATION; ESCHERICHIA COLI; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERIZATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; RNA BINDING; RNA CONFORMATION; RNA SEQUENCE; SITE DIRECTED MUTAGENESIS; ULTRACENTRIFUGATION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; GENETICS; HUMAN; METABOLISM; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN MULTIMERIZATION;

AMINO ACID MOTIFS; BINDING SITES; CIRCULAR DICHROISM; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RNA; RNA-BINDING PROTEINS;

EID: 84921957282     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.1080/15476286.2014.996069     Document Type: Article

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