-
1
-
-
73749083481
-
Global estimates of the prevalence of diabetes for 2010 and 2030
-
Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010;87:4-14
-
(2010)
Diabetes Res Clin Pract
, vol.87
, pp. 4-14
-
-
Shaw, J.E.1
Sicree, R.A.2
Zimmet, P.Z.3
-
2
-
-
53049084871
-
The road from obesity to type 2 diabetes
-
Ioannidis I. The road from obesity to type 2 diabetes. Angiology 2008;59(Suppl. 2):39S-43S
-
(2008)
Angiology
, vol.59
, pp. 39S-43S
-
-
Ioannidis, I.1
-
3
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes GT, Yang Q, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003;112:1821-1830
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
-
4
-
-
78650781728
-
Effects of inhibition of interleukin-6 signalling on insulin sensitivity and lipoprotein (a) levels in human subjects with rheumatoid diseases
-
Schultz O, Oberhauser F, Saech J, et al. Effects of inhibition of interleukin-6 signalling on insulin sensitivity and lipoprotein (a) levels in human subjects with rheumatoid diseases. PLoS ONE 2010;5:e14328
-
(2010)
PLoS ONE
, vol.5
, pp. e14328
-
-
Schultz, O.1
Oberhauser, F.2
Saech, J.3
-
5
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 1996;271:665-668
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
6
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
Winer S, Chan Y, Paltser G, et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009;15:921-929
-
(2009)
Nat Med
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
-
7
-
-
70350561703
-
Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle
-
Hong EG, Ko HJ, Cho YR, et al. Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. Diabetes 2009;58:2525-2535
-
(2009)
Diabetes
, vol.58
, pp. 2525-2535
-
-
Hong, E.G.1
Ko, H.J.2
Cho, Y.R.3
-
8
-
-
78651073627
-
IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity
-
Ricardo-Gonzalez RR, Red Eagle A, Odegaard JI, et al. IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity. Proc Natl Acad Sci U S A 2010;107:22617-22622
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 22617-22622
-
-
Ricardo-Gonzalez, R.R.1
Red Eagle, A.2
Odegaard, J.I.3
-
9
-
-
84875548030
-
B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile
-
De Furia J, Belkina AC, Jagannathan-Bogdan M, et al. B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile. Proc Natl Acad Sci U S A 2013;110:5133-5138
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 5133-5138
-
-
De Furia, J.1
Belkina, A.C.2
Jagannathan-Bogdan, M.3
-
10
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112:1796-1808
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
11
-
-
84862986986
-
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
-
Cipolletta D, Feuerer M, Li A, et al. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature 2012;486:549-553
-
(2012)
Nature
, vol.486
, pp. 549-553
-
-
Cipolletta, D.1
Feuerer, M.2
Li, A.3
-
12
-
-
0031762908
-
Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid
-
Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 1998;83:847-850
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 847-850
-
-
Fried, S.K.1
Bunkin, D.A.2
Greenberg, A.S.3
-
13
-
-
26444537419
-
The pro-inflammatory cytokine IL-18 is expressed in human adipose tissue and strongly upregulated by TNFalpha in human adipocytes
-
Wood IS, Wang B, Jenkins JR, Trayhurn P. The pro-inflammatory cytokine IL-18 is expressed in human adipose tissue and strongly upregulated by TNFalpha in human adipocytes. Biochem Biophys Res Commun 2005;337:422-429
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 422-429
-
-
Wood, I.S.1
Wang, B.2
Jenkins, J.R.3
Trayhurn, P.4
-
14
-
-
80053274395
-
B cell-activating factor controls the production of adipokines and induces insulin resistance
-
Hamada M, Abe M, Miyake T, et al. B cell-activating factor controls the production of adipokines and induces insulin resistance. Obesity (Silver Spring) 2011;19:1915-1922
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 1915-1922
-
-
Hamada, M.1
Abe, M.2
Miyake, T.3
-
15
-
-
84899644440
-
B lymphocyte stimulator (BLyS) is expressed in human adipocytes in vivo and is related to obesity but not to insulin resistance
-
Müller N, Schulte DM, Hillebrand S, et al. B lymphocyte stimulator (BLyS) is expressed in human adipocytes in vivo and is related to obesity but not to insulin resistance. PLoS ONE 2014;9:e94282
-
(2014)
PLoS ONE
, vol.9
, pp. e94282
-
-
Müller, N.1
Schulte, D.M.2
Hillebrand, S.3
-
16
-
-
85027938385
-
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
-
Winer DA, Winer S, Shen L, et al. B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med 2011;17:610-617
-
(2011)
Nat Med
, vol.17
, pp. 610-617
-
-
Winer, D.A.1
Winer, S.2
Shen, L.3
-
17
-
-
78650600361
-
The double life of a B-1 cell: Self-reactivity selects for protective effector functions
-
Baumgarth N. The double life of a B-1 cell: self-reactivity selects for protective effector functions. Nat Rev Immunol 2011;11:34-46
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 34-46
-
-
Baumgarth, N.1
-
18
-
-
0021838305
-
Progenitors for Ly-1 B cells are distinct from progenitors for other B cells
-
Hayakawa K, Hardy RR, Herzenberg LA, Herzenberg LA. Progenitors for Ly-1 B cells are distinct from progenitors for other B cells. J Exp Med 1985;161:1554-1568
-
(1985)
J Exp Med
, vol.161
, pp. 1554-1568
-
-
Hayakawa, K.1
Hardy, R.R.2
Herzenberg, L.A.3
Herzenberg, L.A.4
-
19
-
-
0033515101
-
Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system
-
Baumgarth N, Herman OC, Jager GC, Brown L, Herzenberg LA, Herzenberg LA. Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system. Proc Natl Acad Sci U S A 1999;96:2250-2255
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2250-2255
-
-
Baumgarth, N.1
Herman, O.C.2
Jager, G.C.3
Brown, L.4
Herzenberg, L.A.5
Herzenberg, L.A.6
-
20
-
-
70149098555
-
Nonredundant roles for B cell-derived IL-10 in immune counter-regulation
-
Madan R, Demircik F, Surianarayanan S, et al. Nonredundant roles for B cell-derived IL-10 in immune counter-regulation. J Immunol 2009;183:2312-2320
-
(2009)
J Immunol
, vol.183
, pp. 2312-2320
-
-
Madan, R.1
Demircik, F.2
Surianarayanan, S.3
-
21
-
-
84873313098
-
Human "orchestrator" CD11b (+) B1 cells spontaneously secrete IL-10 and regulate T cell activity
-
Griffin DO, Rothstein TL. Human "orchestrator" CD11b (+) B1 cells spontaneously secrete IL-10 and regulate T cell activity. Mol Med 2012;18:1003-1008.
-
(2012)
Mol Med
, vol.18
, pp. 1003-1008
-
-
Griffin, D.O.1
Rothstein, T.L.2
-
22
-
-
84887419072
-
Adipose natural regulatory B cells negatively control adipose tissue inflammation
-
Nishimura S, Manabe I, Takaki S, et al. Adipose natural regulatory B cells negatively control adipose tissue inflammation. Cell Metab 2013;18:759-766
-
(2013)
Cell Metab
, vol.18
, pp. 759-766
-
-
Nishimura, S.1
Manabe, I.2
Takaki, S.3
-
23
-
-
80053574700
-
B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions
-
Kyaw T, Tay C, Krishnamurthi S, et al. B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions. Circ Res 2011;109:830-840
-
(2011)
Circ Res
, vol.109
, pp. 830-840
-
-
Kyaw, T.1
Tay, C.2
Krishnamurthi, S.3
-
24
-
-
0342939538
-
Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity
-
Shaw PX, Hörkkö S, Chang MK, et al. Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity. J Clin Invest 2000;105:1731-1740
-
(2000)
J Clin Invest
, vol.105
, pp. 1731-1740
-
-
Shaw, P.X.1
Hörkkö, S.2
Chang, M.K.3
-
25
-
-
55649105421
-
Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women
-
McLaughlin T, Deng A, Gonzales O, et al. Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women. Diabetologia 2008;51:2303-2308
-
(2008)
Diabetologia
, vol.51
, pp. 2303-2308
-
-
McLaughlin, T.1
Deng, A.2
Gonzales, O.3
-
26
-
-
33749147435
-
Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein E-null mice
-
Faria-Neto JR, Chyu KY, Li X, et al. Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein E-null mice. Atherosclerosis 2006;189:83-90
-
(2006)
Atherosclerosis
, vol.189
, pp. 83-90
-
-
Faria-Neto, J.R.1
Chyu, K.Y.2
Li, X.3
-
27
-
-
0033020662
-
Intestinal reperfusion injury is mediated by IgM and complement
-
Williams JP, Pechet TT, Weiser MR, et al. Intestinal reperfusion injury is mediated by IgM and complement. J Appl Physiol (1985) 1999;86:938-942
-
(1985)
J Appl Physiol
, vol.86
, pp. 938-942
-
-
Williams, J.P.1
Pechet, T.T.2
Weiser, M.R.3
-
28
-
-
0023856770
-
The half-lives of serum immunoglobulins in adult mice
-
Vieira P, Rajewsky K. The half-lives of serum immunoglobulins in adult mice. Eur J Immunol 1988;18:313-316
-
(1988)
Eur J Immunol
, vol.18
, pp. 313-316
-
-
Vieira, P.1
Rajewsky, K.2
-
29
-
-
66449085101
-
Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans
-
Chou MY, Fogelstrand L, Hartvigsen K, et al. Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans. J Clin Invest 2009;119:1335-1349
-
(2009)
J Clin Invest
, vol.119
, pp. 1335-1349
-
-
Chou, M.Y.1
Fogelstrand, L.2
Hartvigsen, K.3
-
30
-
-
80355133234
-
Macrophage-mediated inflammation in metabolic disease
-
Chawla A, Nguyen KD, Goh YP. Macrophage-mediated inflammation in metabolic disease. Nat Rev Immunol 2011;11:738-749
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 738-749
-
-
Chawla, A.1
Nguyen, K.D.2
Goh, Y.P.3
-
31
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007;117:175-184
-
(2007)
J Clin Invest
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
32
-
-
70449113184
-
Human adipose tissue macrophages: M1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss
-
Aron-Wisnewsky J, Tordjman J, Poitou C, et al. Human adipose tissue macrophages: m1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss. J Clin Endocrinol Metab 2009;94:4619-4623
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 4619-4623
-
-
Aron-Wisnewsky, J.1
Tordjman, J.2
Poitou, C.3
-
33
-
-
84883632289
-
Glucose impairs B-1 cell function in diabetes
-
Jennbacken K, Ståhlman S, Grahnemo L, Wiklund O, Fogelstrand L. Glucose impairs B-1 cell function in diabetes. Clin Exp Immunol 2013;174:129-138.
-
(2013)
Clin Exp Immunol
, vol.174
, pp. 129-138
-
-
Jennbacken, K.1
Ståhlman, S.2
Grahnemo, L.3
Wiklund, O.4
Fogelstrand, L.5
-
34
-
-
0032525007
-
Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM
-
Boes M, Esau C, Fischer MB, Schmidt T, Carroll M, Chen J. Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM. J Immunol 1998;160:4776-4787
-
(1998)
J Immunol
, vol.160
, pp. 4776-4787
-
-
Boes, M.1
Esau, C.2
Fischer, M.B.3
Schmidt, T.4
Carroll, M.5
Chen, J.6
-
35
-
-
0035860559
-
An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
-
Schiemann B, Gommerman JL, Vora K, et al. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 2001;293:2111-2114
-
(2001)
Science
, vol.293
, pp. 2111-2114
-
-
Schiemann, B.1
Gommerman, J.L.2
Vora, K.3
-
36
-
-
84855369823
-
Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation
-
Kyaw T, Tay C, Hosseini H, et al. Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation. PLoS ONE 2012;7:e29371
-
(2012)
PLoS ONE
, vol.7
, pp. e29371
-
-
Kyaw, T.1
Tay, C.2
Hosseini, H.3
-
37
-
-
0036795531
-
B cells regulate autoimmunity by provision of IL-10
-
Fillatreau S, Sweenie CH, McGeachy MJ, Gray D, Anderton SM. B cells regulate autoimmunity by provision of IL-10. Nat Immunol 2002;3:944-950
-
(2002)
Nat Immunol
, vol.3
, pp. 944-950
-
-
Fillatreau, S.1
Sweenie, C.H.2
McGeachy, M.J.3
Gray, D.4
Anderton, S.M.5
-
38
-
-
0037450740
-
Prevention of arthritis by interleukin 10-producing B cells
-
Mauri C, Gray D, Mushtaq N, Londei M. Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 2003;197:489-501
-
(2003)
J Exp Med
, vol.197
, pp. 489-501
-
-
Mauri, C.1
Gray, D.2
Mushtaq, N.3
Londei, M.4
-
39
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, et al. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 2007;447:1116-1120
-
(2007)
Nature
, vol.447
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
-
40
-
-
77956114905
-
Macrophage polarization to a unique phenotype driven by B cells
-
Wong SC, Puaux AL, Chittezhath M, et al. Macrophage polarization to a unique phenotype driven by B cells. Eur J Immunol 2010;40:2296-2307
-
(2010)
Eur J Immunol
, vol.40
, pp. 2296-2307
-
-
Wong, S.C.1
Puaux, A.L.2
Chittezhath, M.3
-
41
-
-
8144231243
-
Interleukin-10 secreted by B-1 cells modulates the phagocytic activity of murine macrophages in vitro
-
Popi AF, Lopes JD, Mariano M. Interleukin-10 secreted by B-1 cells modulates the phagocytic activity of murine macrophages in vitro. Immunology 2004;113:348-354
-
(2004)
Immunology
, vol.113
, pp. 348-354
-
-
Popi, A.F.1
Lopes, J.D.2
Mariano, M.3
-
42
-
-
79251595805
-
B-1 cells temper endotoxemic inflammatory responses
-
Barbeiro DF, Barbeiro HV, Faintuch J, et al. B-1 cells temper endotoxemic inflammatory responses. Immunobiology 2011;216:302-308
-
(2011)
Immunobiology
, vol.216
, pp. 302-308
-
-
Barbeiro, D.F.1
Barbeiro, H.V.2
Faintuch, J.3
-
43
-
-
84881551373
-
Activation of adipose tissue macrophages in obese mice does not require lymphocytes
-
Behan JW, Ehsanipour EA, Sheng X, et al. Activation of adipose tissue macrophages in obese mice does not require lymphocytes. Obesity (Silver Spring) 2013;21:1380-1388.
-
(2013)
Obesity (Silver Spring)
, vol.21
, pp. 1380-1388
-
-
Behan, J.W.1
Ehsanipour, E.A.2
Sheng, X.3
-
44
-
-
84856568116
-
Natural IgM in immune equilibrium and harnessing their therapeutic potential
-
Kaveri SV, Silverman GJ, Bayry J. Natural IgM in immune equilibrium and harnessing their therapeutic potential. J Immunol 2012;188:939-945
-
(2012)
J Immunol
, vol.188
, pp. 939-945
-
-
Kaveri, S.V.1
Silverman, G.J.2
Bayry, J.3
-
45
-
-
70449710443
-
IgM antibodies to apoptosisassociated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells
-
Chen Y, Park YB, Patel E, Silverman GJ. IgM antibodies to apoptosisassociated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells. J Immunol 2009;182:6031-6043
-
(2009)
J Immunol
, vol.182
, pp. 6031-6043
-
-
Chen, Y.1
Park, Y.B.2
Patel, E.3
Silverman, G.J.4
-
46
-
-
27444437321
-
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
-
Cinti S, Mitchell G, Barbatelli G, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005;46:2347-2355
-
(2005)
J Lipid Res
, vol.46
, pp. 2347-2355
-
-
Cinti, S.1
Mitchell, G.2
Barbatelli, G.3
-
47
-
-
0025353845
-
Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits
-
Rosenfeld ME, Palinski W, Ylä-Herttuala S, Butler S, Witztum JL. Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits. Arteriosclerosis 1990;10:336-349
-
(1990)
Arteriosclerosis
, vol.10
, pp. 336-349
-
-
Rosenfeld, M.E.1
Palinski, W.2
Ylä-Herttuala, S.3
Butler, S.4
Witztum, J.L.5
-
48
-
-
55749115444
-
BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact
-
Scholz JL, Crowley JE, Tomayko MM, et al. BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact. Proc Natl Acad Sci U S A 2008;105:15517-15522.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 15517-15522
-
-
Scholz, J.L.1
Crowley, J.E.2
Tomayko, M.M.3
-
49
-
-
84874595985
-
Blockade of B-cell-activating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity
-
Kawasaki K, Abe M, Tada F, et al. Blockade of B-cell-activating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity. Lab Invest 2013;93:311-321
-
(2013)
Lab Invest
, vol.93
, pp. 311-321
-
-
Kawasaki, K.1
Abe, M.2
Tada, F.3
|