A review of the biology of calcium phosphate sequestration with special reference to milk

Dairy Science and Technology

Volumn 95, Issue 1, 2015, Pages 3-14

  Lenton, Samuel ^a,b   Nylander, Tommy ^c   Teixeira, Susana C M ^a,b   Holt, Carl ^d  

^a KEELE UNIVERSITY   (United Kingdom)

^b INSTITUT LAUE LANGEVIN   (France)

^c LUND UNIVERSITY   (Sweden)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Amorphous calcium phosphate; Blood; Bone; Milk; Saliva; Tooth; Urine

Indexed keywords

BIOLOGY; BIOMINERALIZATION; BLOOD; BODY FLUIDS; BONE; CALCIUM; CASEIN; NANOCLUSTERS; PHOSPHATE MINERALS; PHYSIOLOGY; REPAIR;

AMORPHOUS CALCIUM PHOSPHATE; MILK; SALIVA; TOOTH; URINE;

CALCIUM PHOSPHATE;

EID: 84921932504     PISSN: 19585586     EISSN: 19585594     Source Type: Journal    
DOI: 10.1007/s13594-014-0177-2     Document Type: Review

References (50)

1. Aoki T, Umeda T, Kako Y (1992) The least number of phosphate groups for cross-linking of casein by colloidal calcium phosphate. J Dairy Sci 75(4):971–975
2. Boskey AL, Chiang P, Fermanis A, Brown J, Taleb H, David V, Rowe PSN (2010) MEPE’s diverse effects on mineralization. Calcif Tissue Int 86(1):42–46. doi:10.1007/s00223-009-9313-z
3. Christensen B, Sorensen ES (2014) Osteopontin is highly susceptible to cleavage in bovine milk and the proteolytic fragments bind the alpha (v) beta (3)-integrin receptor. J Dairy Sci 97(1):136–146. doi:10.3168/jds.2013-7223
4. Christoffersen MR, Christoffersen J, Kibalczyc W (1990) Apparent solubilities of 2 amorphous calcium phosphates and of octacalcium phosphate in the temperature-range 30-42degrees-C. J Crystal Growth 106(2–3):349–354. doi:10.1016/0022-0248(90)90079-z
5. Clegg RA, Holt C (2009) An E. coli over-expression system for multiply-phosphorylated proteins and its use in a study of calcium phosphate sequestration by novel recombinant phosphopeptides. Protein Expr Purif 67(1):23–34. doi:10.1016/j.pep.2009.04.004
6. Combes C, Rey C (2010) Amorphous calcium phosphates: synthesis, properties and uses in biomaterials. Acta Biomaterialia 6 (9):3362–3378. doi:http://dx.doi.org/10.1016/j.actbio.2010.02.017
7. Dorozhkin SV (2011) Calcium orthophosphates: occurrence, properties, biomineralization, pathological calcification and biomimetic applications. Biomatter 1(2):121–164. doi:10.4161/biom.18790
8. Elliot JC (1994) Structure and chemistry of the apatites and other calcium orthophosphates. Studies in inorganic chemistry. vol 18. Elsevier, Amsterdam, The Netherlands
9. Fedarko NS, Jain A, Karadag A, Fisher LW (2004) Three small integrin-binding ligand N-linked glycoproteins (SIBLINGs) bind and activate specific matrix metalloproteinases. FASEB J. 18 (2):734 − +. doi:10.1096/fj.03-0966fje
10. Fisher LW, Torchia DA, Fohr B, Young MF, Fedarko NS (2001) Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontin. Biochem Biophys Res Commun 280(2):460–465
11. Gebauer D, Coelfen H (2011) Prenucleation clusters and non-classical nucleation. Nano Today 6(6):564–584. doi:10.1016/j.nantod.2011.10.005
12. Gebauer D, Völkel A, Cölfen H (2008) Stable prenucleation calcium carbonate clusters. Science 322(5909):1819–1822. doi:10.1126/science.1164271
13. George A, Veis A (2008) Phosphorylated proteins and control over apatite nucleation, crystal growth, and inhibition. Chem Rev 108(11):4670–4693. doi:10.1021/cr0782729
14. Gericke A, Qin C, Sun Y, Redfern R, Redfern D, Fujimoto Y, Taleb H, Butler WT, Boskey AL (2010) Different forms of DMP1 play distinct roles in mineralization. J Dent Res 89(4):355–359. doi:10.1177/0022034510363250
15. Grøn P (1973) Saturation of human saliva with calcium phosphates. Arch Oral Biol 18(11):1385–1392. doi:10.1016/0003-9969(73)90112-x
16. Heiss A, Pipich V, Jahnen-Dechent W, Schwahn D (2010) Fetuin-A is a mineral carrier protein: small angle neutron scattering provides new insight on fetuin-A controlled calcification inhibition. Biophys J 99(12):3986–3995. doi:10.1016/j.bpj.2010.10.030
17. Holt C (1982) Inorganic constituents of milk 3. The colloidal calcium phosphate of cows’ milk. J Dairy Res 49(1):29–38
18. Holt C (2004) An equilibrium thermodynamic model of the sequestration of calcium phosphate by casein micelles and its application to the calculation of the partition of salts in milk. Eur Biophys J with Biophys Lett 33(5):421–434. doi:10.1007/s00249-003-0377-9
19. Holt C, Dalgleish DG, Jenness R (1981) Inorganic constituents of milk. 2. Calculation of the ion equilibria in milk diffusate and comparison with experiment. Anal Biochem 113(1):154–163. doi:10.1016/0003-2697(81)90059-2
20. Holt C, Vankemenade M, Nelson LS, Hukins DWL, Bailey RT, Harries JE, Hasnain SS, Debruyn PL (1989) Amorphous calcium phosphates prepared at ph 6.5 and 6.0. Mater Res Bull Am Meteorol Soc 24(1):55–62. doi:10.1016/0025-5408(89)90008-1
21. Holt C, de Kruif CG, Tuinier R, Timmins PA (2003) Substructure of bovine casein micelles by small-angle X-ray and neutron scattering. Coll Surf-Physicocheml Eng A Sp 213(2–3):275–284
22. Holt C, Sorensen ES, Clegg RA (2009) Role of calcium phosphate nanoclusters in the control of calcification. FEBS J 276(8):2308–2323. doi:10.1111/j.1742-4658.2009.06958.x
23. Holt C, Lenton S, Nylander T, Teixeira SCM (2014) Mineralisation of soft and hard tissues and the stability of biofluids. J. Struct. Biol. 185:383–396. doi:http://dx.doi.org/10.1016/j.jsb.2013.11.009
24. Jahnen-Dechent W, Schafer C, Ketteler M, McKee MD (2008) Mineral chaperones: a role for fetuin-A and osteopontin in the inhibition and regression of pathologic calcification. J Mol Med-Jmm 86(4):379–389. doi:10.1007/s00109-007-0294-y
25. Jahnen-Dechent W, Heiss A, Schaefer C, Ketteler M (2011) Fetuin-A regulation of calcified matrix metabolism. Circulation Res 108(12):1494–1509. doi:10.1161/circresaha.110.234260
26. Kawasaki K, Weiss KM (2003) Mineralized tissue and vertebrate evolution: the secretory calcium-binding phosphoprotein gene cluster. Proc Natl Acad Sci U S A 100(7):4060–4065. doi:10.1073/pnas.0638023100
27. Kawasaki K, Suzuki T, Weiss KM (2004) Genetic basis for the evolution of vertebrate mineralized tissue. Proc Natl Acad Sci U S A 101(31):11356–11361. doi:10.1073/pnas.0404279101
28. Little EM, Holt C (2004) An equilibrium thermodynamic model of the sequestration of calcium phosphate by casein phosphopeptides. Eur Biophys J with Biophys Lett 33(5):435–447. doi:10.1007/s00249-003-0376-x
29. Lyster RLJ (1981) Calculation by computer of individual concentrations in a simulated milk salt solution. 2. An extension to the previous model. J Dairy Res 48(1):85–89
30. Mazzali M, Kipari T, Ophascharoensuk V, Wesson JA, Johnson R, Hughes J (2002) Osteopontin—a molecule for all seasons. QJM -an Int J Med 95(1):3–13
31. McMahon DJ, Oommen BS (2012) Casein micelle structure, functions and interactions. In: Fox PF, McSweeney PLH (eds) Advanced dairy chemistry, vol 1A Proteins: basic aspects. 4th edn. Springer, pp 185–210
32. Mekmene O, Le Graet Y, Gaucheron F (2009) A model for predicting salt equilibria in milk and mineral-enriched milks. Food Chem 116(1):233–239. doi:10.1016/j.foodchem.2009.02.039
33. Mekmene O, Le Graet Y, Gaucheron F (2010) Theoretical model for calculating ionic equilibria in milk as a function of pH: comparison to experiment. J Agric Food Chem 58(7):4440–4447. doi:10.1021/jf903628r
34. Meyer JL, Eanes ED (1978) Thermodynamic analysis of secondary transition in spontaneous precipitation of calcium-phosphate. Calcif Tissue Res 25(3):209–216. doi:10.1007/bf02010771
35. Nudelman F, Pieterse K, George A, Bomans PHH, Friedrich H, Brylka LJ, Hilbers PAJ, de With G, Sommerdijk NAJM (2010) The role of collagen in bone apatite formation in the presence of hydroxyapatite nucleation inhibitors. Nature Mater 9(12):1004–1009. doi:10.1038/nmat2875
36. Nudelman F, Bomans PHH, George A, de With G, Sommerdijk NAJM (2012) The role of the amorphous phase on the biomimetic mineralization of collagen. Faraday Discuss 159:357–370. doi:10.1039/c2fd20062g
37. Olszta MJ, Douglas EP, Gower LB (2003) Scanning electron microscopic analysis of the mineralization of type I collagen via a polymer-induced liquid-precursor (PILP) process. Calcif Tissue Int 72(5):583–591. doi:10.1007/s00223-002-1032-7
38. Olszta MJ, Cheng X, Jee SS, Kumar R, Kim Y-Y, Kaufman MJ, Douglas EP, Gower LB (2007) Bone structure and formation: a new perspective. Mater Sci Eng Rep 58(3–5):77–116. doi:10.1016/j.mser.2007.05.001
39. Price PA, Nguyen TMT, Williamson MK (2003) Biochemical characterization of the serum fetuin-mineral complex. J Biol Chem 278(24):22153–22160. doi:10.1074/jbc.M300739200
40. Rice G, Barber A, O'Connor A, Stevens G, Kentish S (2010) A theoretical and experimental analysis of calcium speciation and precipitation in dairy ultrafiltration permeate. Int Dairy J 20(10):694–706. doi:10.1016/j.idairyj.2010.03.004
41. Rodriguez DE, Thula T, Toro EJ, Yeh Y-W, Holt C, Holliday LS, Gower LB (2014) Multifunctional role of osteopontin in directing intrafibrillar mineralization of collagen and activation of osteoclasts. Acta Biomaterialia 10(1):494–507
42. Sfeir C, Fang P-A, Jayaraman T, Raman A, Xiaoyuan Z, Beniash E (2014) Synthesis of bone-like nanocomposites using multiphosphorylated peptides. Acta Biomaterialia 10(5):2241–2249. doi:10.1016/j.actbio.2014.01.007
43. Termine JD, Eanes ED (1972) Comparative chemistry of amorphous and apatitic calcium phosphate preparations. Calcif. Tissue Res. 10 (3):171-&. doi:10.1007/bf02012548
44. Wald J, Wiese S, Eckert T, Jahnen-Dechent W, Heiss A, Richtering W (2011a) Fetuin-A mediated formation and ripening of colloidal calciprotein particles. Eur Biophys J with Biophys Lett 40:64–65
45. Wald J, Wiese S, Eckert T, Jahnen-Dechent W, Richtering W, Heiss A (2011b) Formation and stability kinetics of calcium phosphate-fetuin-A colloidal particles probed by time-resolved dynamic light scattering. Soft Matter 7(6):2869–2874
46. Walser M (1961) Ion association 6. Interactions between calcium, magnesium, inorganic phosphate, citrate and protein in normal human plasma. J. Clin. Investig. 40 (4):723-&. doi:10.1172/jci104306
47. Walser M (1962) Separate effects of hyperparathyroidism, hypercalcaemia of malignancy, renal failure, and acidosis on state of calcium, phosphate and other ions in plasma. J. Clin. Investig. 41 (7):1454-&. doi:10.1172/jci104601
48. Wang L, Nancollas GH (2009) Pathways to biomineralization and biodemineralization of calcium phosphates: the thermodynamic and kinetic controls. Dalton Trans 15:2665–2672. doi:10.1039/b815887h
49. White JCD, Davies DT (1958) The relation between the chemical composition of milk and the stability of the caseinate complex. 1 General introduction, description of samples, methods and chemical composition of samples. J Dairy Res 25(2):236–255
50. Wuthier RE, Rice GS, Wallace JEB, Weaver RL, Legeros RZ, Eanes ED (1985) In vitro precipitation of calcium-phosphate under intracellular conditions—formation of brushite from an amorphous precursor in the absence of ATP. Calcif Tissue Int 37(4):401–410. doi:10.1007/bf02553710