The role of collagen in bone apatite formation in the presence of hydroxyapatite nucleation inhibitors

Nature Materials

Volumn 9, Issue 12, 2010, Pages 1004-1009

  Nudelman, Fabio ^a   Pieterse, Koen ^a   George, Anne ^b   Bomans, Paul H H ^a   Friedrich, Heiner ^a   Brylka, Laura J ^a   Hilbers, Peter A J ^a   De With, Gijsbertus ^a   Sommerdijk, Nico A J M ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APATITE; BONE; CRYOGENICS; ELECTRIC IMPEDANCE TOMOGRAPHY; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; HYDROXYAPATITE; MINERALOGY; NUCLEATION; PHOSPHATE MINERALS; TRANSMISSION ELECTRON MICROSCOPY;

AMORPHOUS CALCIUM PHOSPHATE; CHARGED AMINO ACIDS; COLLAGEN MATRICES; COLLAGEN MOLECULES; CRYOGENIC TRANSMISSION ELECTRON MICROSCOPY; ELECTRON TOMOGRAPHY; NON-COLLAGENOUS PROTEINS; SUPRAMOLECULAR ASSEMBLIES;

COLLAGEN;

AMORPHOUS CALCIUM PHOSPHATE; APATITE; CALCIUM PHOSPHATE; COLLAGEN TYPE 1; HYDROXYAPATITE; NANOPARTICLE; PEPTIDE; POLYASPARTIC ACID;

ANIMAL; ARTICLE; BONE; BONE DEVELOPMENT; CHEMICAL STRUCTURE; CHEMISTRY; CRYOELECTRON MICROSCOPY; CRYOPRESERVATION; DRUG ANTAGONISM; ELECTRON TOMOGRAPHY; EXTRACELLULAR MATRIX; HORSE; LIGHT; METABOLISM; METHODOLOGY; RADIATION SCATTERING; SPECTROMETRY; STAINING; SURFACE PROPERTY; TENDON;

ANIMALS; APATITES; BONE AND BONES; CALCIUM PHOSPHATES; COLLAGEN TYPE I; CRYOELECTRON MICROSCOPY; CRYOPRESERVATION; DURAPATITE; ELECTRON MICROSCOPE TOMOGRAPHY; EXTRACELLULAR MATRIX; HORSES; LIGHT; MODELS, MOLECULAR; NANOPARTICLES; OSTEOGENESIS; PEPTIDES; SCATTERING, RADIATION; SPECTROMETRY, X-RAY EMISSION; STAINING AND LABELING; SURFACE PROPERTIES; TENDONS;

EID: 78649390387     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nmat2875     Document Type: Article

References (31)

1. Hulmes, D. J. S., Wess, T. J., Prockop, D. J. & Fratzl, P. Radial packing, order, and disorder in collagen fibrils. Biophys. J. 68, 1661-1670 (1995).
2. Traub, W., Arad, T. & Weiner, S. 3-dimensional ordered distribution of crystals in turkey tendon collagen-fibers. Proc. Natl Acad. Sci. USA 86, 9822-9826 (1989)
3. Hodge, A. J. & Petruska, J. A. in Aspects of Protein Structure (ed. Ramachandran, G. N.) 289-300 (Academic, 1963).
4. Miller, A. Collagen: The organic matrix of bone. Phil. Trans. R. Soc. B 304, 455-477 (1984)
5. Orgel, J. P. R. O., Irving, T. C., Miller, A. & Wess, T. J. Microfibrillar structure of type I collagen in situ. Proc. Natl Acad. Sci. USA 103, 9001-9005 (2006)
6. Glimcher, M. J. & Muir, H. Recent studies of the mineral phase in bone and its possible linkage to the organic matrix by protein-bound phosphate bonds. Phil. Trans. R. Soc. B 304, 479-508 (1984)
7. Landis, W. J., Song, M. J., Leith, A., Mcewen, L. & Mcewen, B. F. Mineral and organic matrix interaction in normally calcifying tendon visualized in 3 dimensions by high-voltage electron-microscopic tomography and graphic image-reconstruction. J. Struct. Biol. 110, 39-54 (1993).
8. Mahamid, J. et al. Mapping amorphous calcium phosphate transformation into crystalline mineral from the cell to bone in zebrafish fin rays. Proc. Natl Acad. Sci. USA 107, 6316-6321 (2010)
9. Traub, W., Arad, T. & Weiner, S. Origin of mineral crystal-growth in collagen fibrils. Matrix 12, 251-255 (1992).
10. George, A. & Veis, A. Phosphorylated proteins and control over apatite nucleation, crystal growth, and inhibition. Chem. Rev. 108, 4670-4693 (2008).
11. Maitland, M. E. & Arsenault, A. L. A correlation between the distribution of biological apatite and amino-acid-sequence of type-I collagen. Calcif. Tissue Int. 48, 341-352 (1991).
12. Berthet-Colominas, C., Miller, A. & White, S. W. Structural study of the calcifying collagen in turkey leg tendons. J. Mol. Biol. 134, 431-445 (1979).
13. Katz, E. P. & Li, S. Structure and function of bone collagen fibrils. J. Mol. Biol. 80, 1-15 (1973).
14. Landis, W. J. & Silver, F. H. Mineral deposition in the extracellular matrices of vertebrate tissues: Identification of possible apatite nucleation sites on type I collagen. Cells Tissues Organs 189, 20-24 (2009).
15. 3 formation revealed by cryo-TEM. Science 323, 1455-1458 (2009).
16. Stetlerstevenson, W. G. & Veis, A. Type-I collagen shows a specific binding-affinity for bovine dentin phosphophoryn. Calcif. Tissue Int. 38, 135-141 (1986).
17. Stetlerstevenson,W. G. & Veis,A.Bovine dentin phosphophoryn-calcium- ion binding-properties of a high-molecular-weight preparation. Calcif. Tissue Int. 40, 97-102 (1987).
18. Deshpande, A. S. & Beniash, E. Bioinspired synthesis of mineralized collagen fibrils. Cryst. Growth Des. 8, 3084-3090 (2008).
19. Olszta, M. J. et al. Bone structure and formation: A new perspective. Mater. Sci. Eng. R. 58, 77-116 (2007).
20. Price, P. A., Toroian, D. & Lim, J. E. Mineralization by inhibitor exclusion: The calcification of collagen with fetuin. J. Biol. Chem. 284, 17092-17101 (2009).
21. Fratzl, P., Fratzl-Zelman, N. & Klaushofer, K. Collagen packing and mineralization-an X-ray-scattering investigation of turkey leg tendon. Biophys. J. 64, 260-266 (1993).
22. Beniash, E., Traub, W., Veis, A. & Weiner, S. A transmission electron microscope study using vitrified ice sections of predentin: Structural changes in the dentin collagenous matrix prior to mineralization. J. Struct. Biol. 132, 212-225 (2000).
23. Hodge, A. J. & Schmitt, F. O. The charge profile of the tropocollagen macromolecule and the packing arrangement in native-type collagen fibrils. Proc. Natl Acad. Sci. USA 46, 186-197 (1960)
24. Chapman, J. A., Tzaphlidou, M., Meek, K. M. & Kadler, K. E. The collagen fibril-a model system for studying the staining and fixation of a protein. Electron Microsc. Rev. 3, 143-182 (1990).
25. Jee, S. S., Culver, L., Li, Y. P., Douglas, E. P. & Gower, L. B. Biomimetic mineralization of collagen via an enzyme-aided PILP process. J. Cryst. Growth 312, 1249-1256 (2010).
26. Rochette, C. N. et al. A shielding topology stabilizes the early stage protein-mineral complexes of fetuin-a and calcium phosphate: A time-resolved small-angle X-ray study. Chembiochem 10, 735-740 (2009).
27. Toroian, D., Lim, J. E. & Price, P. A. The size exclusion characteristics of type I collagen-implications for the role of noncollagenous bone constituents in mineralization. J. Biol. Chem. 282, 22437-22447 (2007).
28. Kawska, A., Hochrein, O., Brickmann, A., Kniep, R. & Zahn, D. The nucleation mechanism of fluorapatite-collagen composites: Ion association and motif control by collagen proteins. Angew. Chem. Int. Ed. 47, 4982-4985 (2008).
29. He, G. & George, A. Dentin matrix protein 1 immobilized on type I collagen fibrils facilitates apatite deposition in vitro. J. Biol. Chem. 279, 11649-11656 (2004).
30. He, G. et al. Spatially and temporally controlled biomineralization is facilitated by interaction between self-assembled dentin matrix protein 1 and calcium phosphate nuclei in solution. Biochemistry 44, 16140-16148 (2005).
31. Posner, A. S. & Betts, F. Synthetic amorphous calcium phosphate and its relation to bone mineral structure. Acc. Chem. Res. 8, 273-281 (1975).