IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration. Sci Transl Med 6, 230ra44 (2014)

Annals of Neurosciences

Volumn 21, Issue 4, 2014, Pages 150-

  Sharma, Kaushal ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 18; VASCULOTROPIN;

AGE RELATED MACULAR DEGENERATION; ANTIANGIOGENIC ACTIVITY; ARTICLE; COMPARATIVE EFFECTIVENESS; DRUG EFFECT; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; IMMUNOHISTOCHEMISTRY; NONHUMAN; PROTEIN EXPRESSION; SUBRETINAL NEOVASCULARIZATION; VALIDATION STUDY;

EID: 84921924186     PISSN: 09727531     EISSN: 09763260     Source Type: Journal    
DOI: 10.5214/ans.0972.7531.210407     Document Type: Article

References (4)

1. Doyle SL, campbell M, Ozaki E, et al. NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components. Nat. Med. 2012; 18: 791–798.
2. tarallo V, Hirano Y, Gelfand BD, et al. DIcER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. cell 2012; 149: 847–859.
3. Kauppinen A, Niskanen H, Suuronen t, et al. Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells—Implications for age-related macular degeneration (AMD). Immunol. Lett. 2012; 147: 29–33.
4. Tseng WA, Thein T, Kinnunen K, et al. NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: Implications for age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 2013; 54: 110–120.