The role of AtfA and HOG MAPK pathway in stress tolerance in conidia of Aspergillus fumigatus

Fungal Genetics and Biology

Volumn 73, Issue , 2014, Pages 138-149

  Hagiwara, Daisuke ^a   Suzuki, Satoshi ^b   Kamei, Katsuhiko ^a   Gonoi, Tohru ^a   Kawamoto, Susumu ^a  

^a CHIBA UNIVERSITY   (Japan)

^b NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

Author keywords

Aspergillus fumigatus; AtfA; Conidia; MAPK; Stress tolerance; Trehalose

Indexed keywords

ATFA PROTEIN; FUNGAL PROTEIN; GLYCEROL; HOG PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MPKC PROTEIN; SAKA PROTEIN; TRANSCRIPTOME; TREHALOSE; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS FUMIGATUS; BIOACCUMULATION; CATA GENE; CONIDIUM; CONJ GENE; CONTROLLED STUDY; DPRA GENE; ENZYME ACTIVITY; FUNGAL GENE; FUNGAL LIFE CYCLE STAGE; FUNGAL VIABILITY; FUNGUS HYPHAE; GENE CONTROL; NONHUMAN; OSMOLARITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; SCF1 GENE; STRESS; TEMPERATURE SENSITIVITY; FUNGUS SPORE; GENETICS; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ASPERGILLUS FUMIGATUS; FUNGAL PROTEINS; SIGNAL TRANSDUCTION; SPORES, FUNGAL; STRESS, PHYSIOLOGICAL; TRANSCRIPTOME;

EID: 84921916314     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2014.10.011     Document Type: Article

References (33)

1. Al-Bader, N., Vanier, G., Liu, H., Gravelat, F.N., Urb, M., Hoareau, C.M.-Q., Campoli, P., Chabot, J., Filler, S.G., Sheppard, D.C., 2010. Role of trehalose biosynthesis in Aspergillus fumigatus development, stress response, and virulence. Infect. Immun. 78, 3007-3018.
2. Bahn, Y.-S., 2008. Master and commander in fungal pathogens: the two-component system and the HOG signaling pathway. Eukaryot. Cell 7, 2017-2036.
3. Bell, W., Sunt, W., Hohmann, S., Wera, S., Reinders, A., De Virgilio, C., Wiemken, A., Thevelein, J.M., 1998. Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J. Biol. Chem. 273, 33311-33319.
4. Catlett, N.L., Yoder, O.C., Turgeon, B.G., 2003. Whole-genome analysis of twocomponent signal transduction genes in fungal pathogens. Eukaryot. Cell 2, 1151-1161.
5. Elbein, A.D., Pan, Y.T., Pastuszak, I., Carroll, D., 2003. New insights on trehalose: a multifunctional molecule. Glycobiology 13, 17R-27R.
6. Fillinger, S., Chaveroche, M.-K., van Dijck, P., de Vries, R., Ruijter, G., Thevelein, J., d'Enfert, C., 2001. Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans. Microbiology 147, 1851-1862.
7. Furukawa, K., Hoshi, Y., Maeda, T., Nakajima, T., Abe, K., 2005. Aspergillus nidulans HOG pathway is activated only by two-component signalling pathway in response to osmotic stress. Mol. Microbiol. 56, 1246-1261.
8. Gancedo, C., Flores, C.-L., 2004. The importance of a functional trehalose biosynthetic pathway for the life of yeasts and fungi. FEMS Yeast Res. 4, 351-359.
9. Hagiwara, D., Asano, Y., Yamashino, T., Mizuno, T., 2008. Characterization of bZiptype transcription factor AtfA with reference to stress responses of conidia of Aspergillus nidulans. Biosci. Biotechnol. Biochem. 72, 2756-2760.
10. Hagiwara, D., Asano, Y., Marui, J., Furukawa, K., Kanamaru, K., Kato, M., Abe, K., Kobayashi, T., Yamashino, T., Mizuno, T., 2007. The SskA and SrrA response regulators are implicated in oxidative stress responses of hyphae and asexual spores in the phosphorelay signaling network of Aspergillus nidulans. Biosci. Biotechnol. Biochem. 71, 1003-1014.
11. Hagiwara, D., Asano, Y., Marui, J., Yoshimi, A., Mizuno, T., Abe, K., 2009. Transcriptional profiling for Aspergillus nidulans HogA MAPK signaling pathway in response to fludioxonil and osmotic stress. Fungal Genet. Biol. 46, 868-878.
12. Hagiwara, D., Takahashi-Nakaguchi, A., Toyotome, T., Yoshimi, A., Abe, K., Kamei, K., Gonoi, T., Kawamoto, S., 2013. NikA/TcsC histidine kinase is involved in conidiation, hyphal morphology, and responses to osmotic stress and antifungal chemicals in Aspergillus fumigatus. PLoS ONE 8, e80881.
13. Han, K.-H., Prade, R.A., 2002. Osmotic stress-coupled maintenance of polar growth in Aspergillus nidulans. Mol. Microbiol. 43, 1065-1078.
14. Herbert, A.P., Riesen, M., Bloxam, L., Kosmidou, E., Wareing, B.M., Johnson, J.R., Phelan, M.M., Pennington, S.R., Lian, L.-Y., Morgan, A., 2012. NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. PLoS ONE 7, e41975.
15. Hohmann, S., 2002. Osmotic stress signaling and osmoadaptation in yeasts. Microbiol. Mol. Biol. Rev. 66, 300-372.
16. Hoi, J.W.S., Lamarre, C., Beau, R., Meneau, I., Berepiki, A., Barre, A., Mellado, E., Read, N.D., Latgé, J.-P., 2011. A novel family of dehydrin-like proteins is involved in stress response in the human fungal pathogen Aspergillus fumigatus. Mol. Biol. Cell 22, 1896-1906.
17. Kobayashi, T., Abe, K., Asai, K., Gomi, K., Juvvadi, P.R., Kato, M., Kitamoto, K., Takeuchi, M., Machida, M., 2007. Genomics of Aspergillus oryzae. Biosci. Biotechnol. Biochem. 71, 646-670.
18. Krappmann, S., Sasse, C., Braus, G.H., 2006. Gene targeting in Aspergillus fumigatus by homologous recombination is facilitated in a nonhomologous end-joiningdeficient genetic background. Eukaryot. Cell 5, 212-215.
19. Kwon-Chung, K.J., Sugui, J.A., 2013. Aspergillus fumigatus-what makes the species a ubiquitous human fungal pathogen? PLoS Pathog. 9, e1003743.
20. Lara-Rojas, F., Sánchez, O., Kawasaki, L., Aguirre, J., 2011. Aspergillus nidulans transcription factor AtfA interacts with the MAPK SakA to regulate general stress responses, development and spore functions. Mol. Microbiol. 80, 436-454.
21. Latgé, J.-P., 1999. Aspergillus fumigatus and Aspergillosis. Clin. Microbiol. Rev. 12, 310-350.
22. Latgé, J.-P., 2001. The pathobiology of Aspergillus fumigatus. Trends Microbiol. 9, 382-389.
23. Paris, S., Wysong, D., Debeaupuis, J.-P., Shibuya, K., Philippe, B., Diamond, R.D., Latgé, J.-P., 2003. Catalases of Aspergillus fumigatus. Infect. Immun. 71, 3551-3562.
24. Puttikamonkul, S., Willger, S.D., Grahl, N., Perfect, J.R., Movahed, N., Bothner, B., Park, S., Paderu, P., Perlin, D.S., Cramer Jr., R.A., 2010. Trehalose 6-phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus. Mol. Microbiol. 77, 891-911.
25. Reinders, A., Bürckert, N., Hohmann, S., Thevelein, J.M., Boller, T., Wiemken, A., De Virgilio, C., 1997. Structural analysis of the subunits of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae and their function during heat shock. Mol. Microbiol. 24, 687-695.
26. Reyes, G., Romans, A., Nguyen, C.K., May, G.S., 2006. Novel mitogen-activated protein kinase MpkC of Aspergittus fumigatus is required for utilization of polyalcohol sugars. Eukaryot. Cell 5, 1934-1940.
27. Ruijter, G.J.G., Bax, M., Patel, H., Flitter, S.J., Van De Vondervoort, P.J.I., De Vries, R.P., VanKuyk, P.A., Visser, J., 2003. Mannitol is required for stress tolerance in Aspergillus niger conidiospores. Eukaryot. Cell 2, 690-698.
28. Sakamoto, K., Arima, T.-H., Iwashita, K., Yamada, O., Gomi, K., Akita, O., 2008. Aspergillus oryzae atfB encodes a transcription factor required for stress tolerance in conidia. Fungal Genet. Biol. 45, 922-932.
29. Sakamoto, K., Iwashita, K., Yamada, O., Kobayashi, K., Mizuno, A., Akita, O., Mikami, S., Shimoi, H., Gomi, K., 2009. Aspergillus oryzae atfA controls conidial germination and stress tolerance. Fungal Genet. Biol. 46, 887-897.
30. Shinohara, M.L., Correa, A., Bell-Pedersen, D., Dunlap, J.C., Loros, J.J., 2002. Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: Circadian regulation of stress responses and development. Eukaryot. Cell 1, 33-43.
31. Suzuki, S., Sarikaya Bayram, T., Bayram, T., Braus, G.H., 2013. ConF and conJ contribute to conidia germination and stress response in the filamentous fungus Aspergillus nidulans. Fungal Genet. Biol. 56, 42-53.
32. Welker, S., Rudolph, B., Frenzel, E., Hagn, F., Liebisch, G., Schmitz, G., Scheuring, J., Kerth, A., Blume, A., Weinkauf, S., Haslbeck, M., Kessler, H., Buchner, J., 2010. Hsp12 Is an intrinsically unstructured stress protein that folds upon membrane association and modulates membrane function. Mol. Cell 39, 507-520.
33. Wyatt, T.T., Wösten, H.A.B., Dijksterhuis, J., 2013. Fungal spores for dispersion in space and time. Adv. Appl. Microbiol. 85, 42-91.