Risk factors for decline in IQ in youth with type 1 diabetes over the 12 years from diagnosis/illness onset

Diabetes Care

Volumn 38, Issue 2, 2015, Pages 236-242

  Lin, Ashleigh ^a   Northam, Elisabeth A ^b   Werther, George A ^b,c   Cameron, Fergus J ^b,c  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACADEMIC ACHIEVEMENT; ADOLESCENCE; ADULT; ADULTHOOD; ARTICLE; CHILD; CLINICAL EXAMINATION; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; HYPOGLYCEMIA; HYPOGLYCEMIC SEIZURE; INSULIN DEPENDENT DIABETES MELLITUS; INTELLIGENCE QUOTIENT; INTELLIGENCE TEST; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MENTAL DEVELOPMENT; METABOLIC REGULATION; ONSET AGE; PROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SEIZURE; WECHSLER ABBREVIATED SCALE OF INTELLIGENCE; WECHSLER INTELLIGENCE SCALE FOR CHILDREN REVISED; WECHSLER PRESCHOOL AND PRIMARY SCALE OF INTELLIGENCE REVISED; ADOLESCENT; BLOOD; CASE CONTROL STUDY; DIABETIC KETOACIDOSIS; GLUCOSE BLOOD LEVEL; INTELLIGENCE; METABOLISM; PSYCHOLOGY; WECHSLER INTELLIGENCE SCALE; YOUNG ADULT;

GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN;

ADOLESCENT; AGE OF ONSET; BLOOD GLUCOSE; CASE-CONTROL STUDIES; CHILD; DIABETES MELLITUS, TYPE 1; DIABETIC KETOACIDOSIS; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INTELLIGENCE; MALE; PROSPECTIVE STUDIES; RISK FACTORS; WECHSLER SCALES; YOUNG ADULT;

EID: 84921899337     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc14-1385     Document Type: Article

References (36)

1. Tomlinson DR, Gardiner NJ. Glucose neurotoxicity. Nat Rev Neurosci 2008;9:36-45
2. Russo VC, Higgins S, Werther GA, Cameron FJ. Effects of fluctuating glucose levels on neuronal cells in vitro. Neurochem Res 2012;37:1768-1782
3. Arbelaez AM, Semenkovich K, Hershey T. Glycemic extremes in youth with T1DM: the structural and functional integrity of the developing brain. Pediatr Diabetes 2013;14:541-553
4. Antenor-Dorsey JA, Meyer E, Rutlin J, et al. White matter microstructural integrity in youth with type 1 diabetes. Diabetes 2013;62:581-589
5. Aye T, Reiss AL, Kesler S, et al. The feasibility of detecting neuropsychologic and neuroanatomic effects of type 1 diabetes in young children. Diabetes Care 2011;34:1458-1462
6. Aye T, Barnea-Goraly N, Ambler C, et al. White matter structural differences in young children with type 1 diabetes: a diffusion tensor imaging study. Diabetes Care 2012;35:2167-2173
7. Hershey T, Perantie DC, Wu J, Weaver PM, Black KJ, White NH. Hippocampal volumes in youth with type 1 diabetes. Diabetes 2010;59:236-241
8. Ho MS, Weller NJ, Ives FJ, et al. Prevalence of structural central nervous system abnormalities in early-onset type 1 diabetes mellitus. J Pediatr 2008;153:385-390
9. Northam EA, Rankins D, Lin A, et al. Central nervous system function in youth with type 1 diabetes 12 years after disease onset. Diabetes Care 2009;32:445-450
10. Perantie DC, Wu J, Koller JM, et al. Regional brain volume differences associated with hyperglycemia and severe hypoglycemia in youth with type 1 diabetes. Diabetes Care 2007;30:2331-2337
11. Perantie DC, Koller JM, Weaver PM, et al. Prospectively determined impact of type 1 diabetes on brain volume during development. Diabetes 2011;60:3006-3014
12. Barnea-Goraly N, Raman M, Mazaika P, et al.; Diabetes Research in Children Network (DirecNet). Alterations in white matter structure in young children with type 1 diabetes. Diabetes Care 2014;37:332-340
13. Marzelli MJ, Mazaika PK, Barnea-Goraly N, et al.; Diabetes Research in Children Network (DirecNet). Neuroanatomical correlates of dysglycemia in young children with type 1 diabetes. Diabetes 2014;63:343-353
14. Gaudieri PA, Chen R, Greer TF, Holmes CS. Cognitive function in children with type 1 diabetes: a meta-analysis. Diabetes Care 2008;31:1892-1897
15. Hershey T, Perantie DC, Warren SL, Zimmerman EC, Sadler M, White NH. Frequency and timing of severe hypoglycemia affects spatial memory in children with type 1 diabetes. Diabetes Care 2005;28:2372-2377
16. Kaufmann L, Pixner S, Starke M, et al. Neurocognition and brain structure in pediatric patients with type 1 diabetes. J Pediatr Neuroradiol 2012;1:25-35
17. Patiño-Fernández AM, Delamater AM, Applegate EB, et al. Neurocognitive functioning in preschool-age children with type 1 diabetes mellitus. Pediatr Diabetes 2010;11:424-430
18. Cato MA, Mauras N, Ambrosino J, et al.; Diabetes Research in Children Network (DirecNet). Cognitive functioning in young children with type 1 diabetes. J Int Neuropsychol Soc 2014;20:238-247
19. Ly TT, Anderson M, McNamara KA, Davis EA, Jones TW. Neurocognitive outcomes in young adults with early-onset type 1 diabetes: a prospective follow-up study. Diabetes Care 2011;34:2192-2197
20. Lin A, Northam EA, Rankins D, Werther GA, Cameron FJ. Neuropsychological profiles of young people with type 1 diabetes 12 yr after disease onset. Pediatr Diabetes 2010;11:235-243
21. Naguib JM, Kulinskaya E, Lomax CL, Garralda ME. Neuro-cognitive performance in children with type 1 diabetesda meta-analysis. J Pediatr Psychol 2009;34:271-282
22. Perantie DC, Lim A, Wu J, et al. Effects of prior hypoglycemia and hyperglycemia on cognition in children with type 1 diabetes mellitus. Pediatr Diabetes 2008;9:87-95
23. Blasetti A, Chiuri RM, Tocco AM, et al. The effect of recurrent severe hypoglycemia on cognitive performance in children with type 1 diabetes: a meta-analysis. J Child Neurol 2011;26:1383-1391
24. Asvold BO, Sand T, Hestad K, Bjørgaas MR. Cognitive function in type 1 diabetic adults with early exposure to severe hypoglycemia: a 16-year follow-up study. Diabetes Care 2010;33:1945-1947
25. Wechsler D. Manual for the Wechsler Preschool and Primary Scale of Intelligence-Revised. San Antonio, The Psychological Corporation, 1989
26. Wechsler D. Manual for the Wechsler Intelligence Scale for Children-Revised. New York, The Psychological Corporation, 1974
27. Wechsler D. Wechsler Abbreviated Scale of Intelligence Manual. San Antonio, The Psychological Corporation, 1993
28. Bayley N. Manual for the Bayley Scales of Infant Development. San Antonio, The Psychological Corporation, 1969
29. Daniel A. Power, Privilege and Prestige: Occupations in Australia. Melbourne, Longman-Cheshire, 1983
30. Northam EA, Anderson PJ, Jacobs R, Hughes M, Warne GL, Werther GA. Neuropsychological profiles of children with type 1 diabetes 6 years after disease onset. Diabetes Care 2001;24:1541-1546
31. Pell GS, Lin A, Wellard RM, et al. Agerelated loss of brain volume and T2 relaxation time in youth with type 1 diabetes. Diabetes Care 2012;35:513-519
32. Rovet JF, Ehrlich RM. The effect of hypoglycemic seizures on cognitive function in children with diabetes: a 7-year prospective study. J Pediatr 1999;134:503-506
33. Jacobson AM, Musen G, Ryan CM, et al.; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group. Longterm effect of diabetes and its treatment on cognitive function. N Engl J Med 2007;356:1842-1852
34. Cameron FJ, Scratch SE, Nadebaum C, et al.; DKA Brain Injury Study Group. Neurological consequences of diabetic ketoacidosis at initial presentation of type 1 diabetes in a prospective cohort study of children. Diabetes Care 2014;37:1554-1562
35. Northam EA, Lin A, Finch S, Werther GA, Cameron FJ. Psychosocial well-being and functional outcomes in youth with type 1 diabetes 12 years after disease onset. Diabetes Care 2010;33:1430-1437
36. Northam EA, Cameron FJ. Understanding the diabetic brain: new technologies but old challenges. Diabetes 2013;62:341-342