Prevalence of cognitive decline and associated factors in elderly type 2 diabetic patients at inclusion in the GERODIAB cohort

European Geriatric Medicine

Volumn 6, Issue 1, 2015, Pages 36-40

  Verny, C ^a   Doucet, J ^b   Bauduceau, B ^c   Constans, T ^d   Mondon, K ^d   Le Floch, J P ^e   Blickle J F ^f   Bourdel Marchasson, I ^f   Fagot Campagna, A ^f   Lassmann Vague, V ^f   Lecomte, P ^f   Tessier, D ^f  

^a BICÊTRE HOSPITAL   (France)

^b ROUEN UNIVERSITY HOSPITAL   (France)

^c SERVICE D ENDOCRINOLOGIE   (France)

^d CHU BRETONNEAU   (France)

^e Villecresnes Medical Hospital   (France)

^f NONE

Author keywords

Aging; Cognitive decline; Diabetes complications; GERODIAB; Type 2 diabetes

Indexed keywords

ALPHA GLUCOSIDASE INHIBITOR; DIPEPTIDYL PEPTIDASE IV INHIBITOR; GLITAZONE DERIVATIVE; HEMOGLOBIN A1C; INSULIN; METFORMIN;

AGE; AGED; ARTICLE; CEREBROVASCULAR DISEASE; COGNITIVE DEFECT; COHORT ANALYSIS; CONTROLLED STUDY; DIABETIC FOOT; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; FOLLOW UP; GERIATRIC ASSESSMENT; HEART FAILURE; HEMOGLOBIN BLOOD LEVEL; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; NON INSULIN DEPENDENT DIABETES MELLITUS; OBSERVATIONAL STUDY; PERIPHERAL NEUROPATHY; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE;

EID: 84921898323     PISSN: 18787649     EISSN: 18787657     Source Type: Journal    
DOI: 10.1016/j.eurger.2014.10.006     Document Type: Article

References (35)

1. Fagot-Campagna A, Bourdel-Marchasson L, Simon D. Burden of diabetes in an aging population: prevalence, incidence, mortality, characteristics and quality of care. Diabetes Metab 2005;31 Suppl 1(5):S35-52.
2. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diab Res Clin Pract 2010;87:4-14.
3. Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53.
4. 1c with functional disability in older adults: results from the National Health and Nutrition Examination Survey (NHANES), 1999-2006. Diabetes Care 2010;33(5):1055-60.
5. Sinclair AJ, Conroy SP, Bayer AJ. Impact of diabetes on physical function in older people. Diabetes Care 2008;31(2):233-5.
6. Cukierman-Yaffe T, Gerstein HC, Williamson JD, for the action to control cardiovascular risk in diabetes-memory in diabetes (ACCORD-MIND) investigators. Relationship between baseline glycemic control and cognitive function in individuals with type 2 diabetes and other risk factors: the action to control cardiovascular risk in diabetes-memory in diabetes (ACCORD-MIND) trial. Diabetes Care 2009;32:221-6.
7. Yaffe K, Fiocco AJ, Lindquist K, et al. Predictors of maintaining cognitive function in older adults: the Health ABC study. Neurology 2009;72:2029-35.
8. Comijs HC, Kriegsman DM, Dik MG, et al. Somatic chronic diseases and 6-year change in cognitive functioning among older persons. Arch Gerontol Geriatr 2009;48:191-6.
9. Christman AL, Matsumita K, Gottesman RF, et al. Glycatedhaemoglobin and cognitive decline: the Atherosclerosis Risk in Communities (ARIC) study. Diabetologia 2011;54:1645-52.
10. Xu W, Caracciolo B, Wang HX, et al. Accelerated progression from mild cognitive impairment to dementia in people with diabetes. Diabetes 2010; 59:2928-35.
11. Biessels GJ, Staekenborg S, Brunner E, et al. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 2006;5:64-74.
12. Irie F, Fitzpatrick AL, Lopez OL, et al. Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study. Cognition Study. Arch Neurol 2008;65:89-93.
13. Moran C, Phan TG, Chen J, et al. Brain atrophy in type 2 diabetes: regional distribution and influence on cognition. Diabetes Care 2013;36:4036-42.
14. Brown AF, Mangione CM, Saliba D, et al. Guidelines for improving the care of the older person with diabetes mellitus. J Am Geriatr Soc 2003;51:S265-80.
15. Vischer UM, Bauduceau B, Bourdel-Marchasson I, et al. SFGG French-speaking group for study of diabetes in the elderly. A call to incorporate the prevention and treatment of geriatric disorders in the management of diabetes in the elderly. Diabet Metab 2009;35:168-77.
16. Bourdel-Marchasson I, Doucet J, Bauduceau B, et al. for the ALFEDIAM/SFG, French speaking group for study of diabetes in the elderly. Keys priorities in managing glucose control in older people with diabetes. J Nutr Health Aging 2009;13:685-91.
17. Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 2012;55:1577-96.
18. Doucet J, LeFloch JP, Bauduceau B, et al., the SFD/SFGG Intergroup. GERODIAB: Glycaemic control and 5-year morbidity-mortality of type 2 diabetic patients aged 70 years and older: description of the population at inclusion. Diabet Metab 2012;38:523-30.
19. Le Floch JP, Doucet J, Bauduceau B, et al., the SFD/SFGG intergroup. Retinopa-thy, nephropathy, peripheral neuropathy and geriatric scale scores in elderly people with type 2 diabetes. Diabet Med 2014;31:107-11.
20. Bauduceau B, Doucet J, le Floch JP, for the SFD/SFGG intergroup and the GERODIAB group. Cardiovascular events and geriatric scale scores in elderly (70 years-old and above) type 2 diabetic patients at inclusion in the Gerodiab cohort. Diabetes Care 2014;37:304-11.
21. Giannini C, Santoro N, Caprio S, et al. The triglycerides-to-HDL ratio. Association with insulin resistance in obese youths of different ethnic backgrounds. Diabetes Care 2011;34:1869-74.
22. Hugonot-Diener L, Barbeau E, Michel BF, et al. Gremoire : tests et échelles de la Maladie d'Alzheimer et des syndromes apparentés. Collection GRECO (Groupe de REflexion sur les Evaluations Cognitives), Solal Editions; 2008 available online atwww.site-greco.net.
23. Folstein MF, Folstein SE, McHugh PR. Mini-Mental-State. A practical method for grading the cognitive state on patients for the clinician. J Psychiatr Res 1975;12:189-98.
24. Gregg EW, Engelgau MM, Narayan V. Complications of diabetes in elderly people: underappreciated problems include cognitive decline and physical disability. BMJ 2002;325:916-7.
25. Strachan MW, Reynolds RM, Marioni RE, et al. Cognitive function, dementia and type2diabetes mellitusinthe elderly. Nat Rev Endocrinol 2011;7:108-14.
26. Maraldi C, Volpato S, Penninx BW, Yaffe K, et al. Diabetes mellitus, glycemic control, and incident depressive symptoms among 70-to79-year-old persons: the health, aging, and body composition study. Arch Intern Med 2007;167: 1137-44.
27. McGuire LC, Ford ES, Ajani UA. The impact of cognitive functioning on mortality and the development of functional disability in older adults with diabetes: the second longitudinal study on aging. BMC Geriatr 2006;6:8.
28. Whitmer RA, Karter AJ, Yaffe K, Quesenberry Jr CP, Selby JV. Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. JAMA 2009;301:1565-72.
29. Aung PP, Strachan MW, Frier BM, Butcher I, Deary IJ, Price JF. Edinburgh type 2 severe hypoglycaemia and late-life cognitive ability in older people with type 2 diabetes: the Edinburgh type 2 diabetes study. Diabetes Med 2012;29: 328-36.
30. McCoy RG, Van Houten HK, Ziegenfuss JY, Shah ND, Wermers RA, Smith SA. Increased mortality of patients with diabetes reporting severe hypoglycemia. Diabetes Care 2012;35:1897-901.
31. Punthakee Z, Miller ME, Launer LJ, Williamson JD, Lazar RM, Cukierman-Yaffee T, et al. Poor cognitive function and risk of severe hypoglycemia in type 2 diabetes: post hoc epidemiologic analysis of the ACCORD trial. Diabetes Care 2012;35:787-93.
32. Munshi M, Grande L, Hayes M, Ayres D, Suhl E, Capelson R, et al. Cognitive dysfunction is associated with poor diabetes control in older adults. Diabetes Care 2006;29:1794-9.
33. Lee SJ, Boscardin WJ, Cenzer IS, Huang ES, Rice-Trumble K, Eng C. The risks and benefits of implementing glycaemic control guidelines in frail older adults with diabetes mellitus. J Am Geriatr Soc 2011;59:666-72.
34. Pogach L, Aron D. Balancing hypoglycemia glycemic control. A public health approach for insulin safety. JAMA 2010;303:2076-7.
35. Biessels GJ. Brain MRI correlates of cognitive dysfunction in type 2 diabetes: the needle recovered from the haystack? Diabetes Care 2013;36:3855-6.