Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal "mushroom"

Journal of Ethnopharmacology

Volumn 162, Issue , 2015, Pages 323-332

  Glamočlija, Jasmina ^a   Ćirić, Ana ^a   Nikolić, Miloš ^a   Fernandes, Ângela ^b   Barros, Lillian ^b   Calhelha, Ricardo C ^b   Ferreira, Isabel C F R ^b   Soković, Marina ^a   Van Griensven, Leo J L D ^c  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b INSTITUTO POLITÉCNICO DE BRAGANÇA   (Portugal)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Antimicrobial activity; Antioxidant properties; Antiquorum effect; Antitumor activity; Chemical characterization; Inonotus obliquus

Indexed keywords

4 HYDROXYBENZOIC ACID; CARBOXYLIC ACID; CINNAMIC ACID; GALLIC ACID; HYDROXYBENZOIC ACID; INONOTUS OBLIQUUS EXTRACT; OXALIC ACID; PHENOL DERIVATIVE; PROTOCATECHUIC ACID; PYOCYANINE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; DIURETIC AGENT;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIUM CULTURE; BIOLOGICAL ACTIVITY; CANCER CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG POTENCY; DRUG SCREENING; FINLAND; HEPG2 CELL LINE; INONOTUS OBLIQUUS; LIVER CELL CULTURE; LIVER TOXICITY; MCF 7 CELL LINE; NCI H460 CELL LINE; NONHUMAN; PRIMARY CULTURE; PSEUDOMONAS AERUGINOSA; RUSSIAN FEDERATION; THAILAND; TUMOR CELL LINE; AGARICALES; BACTERIUM; CHEMISTRY; DRUG EFFECTS; FUNGUS; HUMAN; LIVER CELL; TRADITIONAL MEDICINE;

BACTERIA (MICROORGANISMS); BASIDIOMYCOTA; INONOTUS OBLIQUUS; PSEUDOMONAS AERUGINOSA; SUS;

AGARICALES; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; BACTERIA; CELL LINE, TUMOR; DIURETICS; FUNGI; HEPATOCYTES; HUMANS; MEDICINE, TRADITIONAL;

EID: 84921857637     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.12.069     Document Type: Article

References (37)

1. Abreu, R.M.V., Ferreira, I.C.F.R., Calhelha, R.C., Lima, R.T., Vasconcelos, M.H., Adega, F., Chaves, R., Querioz, M.J.R.P., 2011. Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno [3,2-b]pyridine-2-carboxylate derivatives: in vitro evaluation, cell cycle analysis and QSAR studies. European Journal of Medicinal Chemistry 46 (12), 5800-5806.
2. Awadh Ali, N.A., Mothana, R.A.A., Lesnau, A., Pilgrim, H., Lindequist, U., 2003. Antiviral activity of Inonotus hispidus. Fitoterapia 74, 483-485.
3. Baraquet, C., Murakami, K., Parsek, M.R., Harwood, C.S., 2012. The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response to c-di-GMP. Nucleic Acids Research 40, 7207-7218.
4. Barros, L., Dueñas, M., Ferreira, I.C.F.R., Baptista, P., Santos-Buelga, C., 2009. Phenolic acids determination by HPLC-DAD-ESI/MS in sixteen different Portuguese wild mushrooms species. Food and Chemical Toxicology 47, 1076-1079.
5. Barros, L., Pereira, C., Ferreira, I.C.F.R., 2013. Optimized analysis of organic acids in edible mushrooms from Portugal by ultra fast liquid chromatography and photodiode array detection. Food Analytical Methods 6, 309-316.
6. Boyle, K.E., Heilmann, S., van Ditmarsch, D., Xavier, J.B., 2013. Exploiting social evolution in biofilms. Current Opinion Microbiology 16, 207-212.
7. Caiazza, N.C., Shanks, R.M., O'Toole, G.A., 2005. Rhamnolipids modulate swarming motility patterns of Pseudomonas aeruginosa. Journal of Bacterioogy 187, 7351-7361.
8. CDC. Antibiotic Resistance Threats in the United States, 2013. U.S Department of Health and Human Services. Centers for Disease Control and Prevention.
9. CLSI, 2009. Clinical and Laboratory Standards Institute Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically. Approved Standard, 8th ed. CLSI Publication M07-A8. Clinical and Laboratory Standards Institute, Wayne, PA.
10. Coates, A., Hu, Y., Bax, R., Page, C., 2002. The future challenges facing the development of a new antimicrobial drugs. Nature Reviews Drug Discovery 1, 895-910.
11. Danchin, E., Giraldeau, L.A., Valone, T.J., Wagner, R.H., 2004. Public information: from nosy neighbours to cultural revolution. Science 305, 487-491.
12. Debnath, T., Park, D.K., Lee, B.R., Jin, H.L., Lee, S.Y., Samad, N.B., Lim, B.O., 2013. Antioxidant activity of Inonotus obliquus grown on germinated brown rice extracts. Journal of Food Biochemistry 37, 456-464.
13. Espinel-Ingroff, A., 2001. Comparation of the E-test with the NCCLS M38-P method for antifungal susceptibility testing of common and emerging pathogenic filamentous fungi. Journal of Clinical Microbiology 39, 1360-1367.
14. Fantuzzi, E., Rezende Anastacio, L., Nicoli, J.R., Oliveira de Paula, S., Esteves Arantes, R.M., Dantas Vanetti, M.C., 2011. Evaluation of Royal Sun Agaricus brasiliensis S. Wasser et al. aqueous extract in mice challenged with Salmonella enterica serovar typhimurium. International Journal of Medicinal Mushrooms 13 (3), 281-288.
15. Fuqua, C., Parsek, M.R., Greenberg, E.P., 2001. Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing. Annual Review of Genetics 35, 439-468.
16. Henrichsen, J., 1972. Bacterial surface translocation: a survey and a classification. Bacteriology Reviews 36, 478-503.
17. Hu, H., Zhang, Z., Lei, Z., Yang, Y., Sugiura, N., 2009. Comparative studies of activity and antiproliferative effect of hot water and ethanol extracts from the mushroom Inonotus obliquus. Journal of Bioscience and Bioengineering 107 (1), 42-48.
18. Jensen, P.O., Bjarnsholt, T., Phipps, R., Rasmussen, T.B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, M., Høiby, N., 2007. Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa. Microbiology 153, 1329-1338.
19. Kim, H.G., Yoon, D.H., Kim, C.H., Shresta, B., Chang, W.C., Lim, S.Y., Lee, W.H., Han, S.G., Lee, J.O., Lim, M.H., Kim, G.Y., Choi, S., Song, W.O., Sung, J.M., Hwang, K.C., Kim, T.W., 2007. Ethanol extract of Inonotus obliquus inhibits lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells. Journal of Medicinal Food 10, 80-89.
20. Kolter, R., Greenberg, E.P., 2006. Microbial sciences: the superficial life of microbes. Nature 441, 300-302.
21. Lai, S., Tremblay, J., Déziel, E., 2009. Swarming motility: a multicellular behaviour conferring antimicrobial resistance. Environmental Microbiology 11, 126-136.
22. Lemieszek, M.K., Langner, E., Kaczor, J., Kandefer-Szerszen, M., Sanecka, B., Mazurkiewicz, W., Rzesky, W., 2011. Anticancer effects of fraction isolated from fruiting bodies of Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae): in vitro studies. International Journal of Medicinal Mushrooms 13 (2), 131-143.
23. Mishra, S.K., Kang, J.H., Kim, D.K., Oh, S.H., Kim, M.K., 2012. Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS) - induced colitis in mice. Journal of Ethnopharmacology 143, 524-532.
24. Monks, A., Scudiero, D., Skehan, P., Shoemaker, R., Paull, K., Vistica, D., Hose, C., Langley, J., Cronise, P., Vaigro-Wolff, A., 1991. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. Journal of the National Cancer Institute 83, 757-766.
25. Murray, T.S., Ledizet, M., Kazmierczak, B.I., 2010. Swarming motility, secretion of type 3 effectors and biofilm formation phenotypes exhibited within a large cohort of Pseudomonas aeruginosa clinical isolates. Journal of Medical Microbiology 59, 511-520.
26. Nakajima, Y., Sato, Y., Konishi, T., 2007. Antioxidant small phenolic ingredients in obliquus (Persoon) Pilat (Chaga). Chemical and Pharmaceutical Bulletin 55, 1222-1226.
27. O'Toole, G.A., Kolter, R., 1998a. Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis. Molecular Microbiology 28, 449-461.
28. O'Toole, G.A., Kolter, R., 1998b. Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development. Molecular Microbiology 30, 295-304.
29. Pereira, E., Barros, L., Martins, A., Ferreira, I.C.F.R., 2012. Towards chemical and nutritional inventory of Portuguese wild edible mushrooms in different habitats. Food Chemistry 130, 394-403.
30. Rasmussen, T.B., Givskov, M., 2006. Quorum sensing inhibitors: a bargain of effects. Microbiology 152, 895-904.
31. Reis, F.S., Martins, A., Barros, L., Ferreira, I.C.F.R., 2012. Antioxidant properties and phenolics profile of the most widely appreciated cultivated mushrooms: a comparative study between in vivo and in vitro samples. Food Chemical and Toxicology 50, 1201-1207.
32. Rumbaugh, K.P., Diggle, S.P., Watters, S.M., Ross-Gillespie, A., Griffin, A.S., West, S.A., 2009. Quorum sensing and the social evolution of bacterial virulence. Current Biology 19, 341-345.
33. Sandy, S.M., Foong-Yee, T., 2012. Anti-quorum sensing and antimicrobial activities of some traditional Chinese medicinal plants commonly used in South-East Asia. Malaysian Journal of Microbiology 8 (1), 11-20.
34. Sokovic, M., Ćirić, A., Glamočlija, J., Nikolić, M., Griensven, L.J.L.D., 2014. Agaricus blazei hot water extract shows anti quorum sensing activity in the nosocomial human pathogen Pseudomonas aeruginosa. Molecules 19, 4189-4199.
35. Song, K.C., Choi, B.L., Shin, J.W., Son, J.Y., Yoo, H.S., Cho, J.H., Lee, Y.W., Son, G.C., Cho, C.K., 2007. Effect of Inonotus obliquus extracts on immunomodulating activity. Korean Journal of Oriental Medicine 28 (4), 27-41.
36. Stojković, D., Reis, F.S., Glamočlija, J., Ćirić, A., Barros, L., Van Griensven, L.J.L.D., Ferreira, I.C.F.R., Soković, M., 2014. Cultivated strains of Agaricus bisporus and A. brasiliensis: chemical characterization and evaluation of antioxidant and antimicrobial properties for final healthy product - natural preservatives in yoghurt. Food and Function 5, 1602-1612.
37. Tsukatani, T., Suenaga, H., Shiga, M., Noguchi, K., Ishiyama, M., Ezoe, T., Matsumoto, K., 2012. Comparison of WST-8 colorimetric method and CLSI broth microdilution method for susceptibility testing against resistant bacteria. Journal of Microbiological Methods 90, 160-166.