Fibroblast growth factor 21 (FGF21) ameliorates collagen-induced arthritis through modulating oxidative stress and suppressing nuclear factor-kappa B pathway

International Immunopharmacology

Volumn 25, Issue 1, 2015, Pages 74-82

  Yu, Yinhang ^a   Li, Siming ^a,e   Liu, Yaonan ^a   Tian, Guiyou ^a   Yuan, Qingyan ^a   Bai, Fuliang ^a   Wang, Wenfei ^a,b   Zhang, Zhiyi ^d   Ren, Guiping ^a,b   Zhang, Yu ^c   Li, Deshan ^a,b  

^a NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^b Key Lab of Agriculture Biological Functional Gene of Heilongjiang Provincial Education Committee   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d HARBIN MEDICAL UNIVERSITY   (China)

^e HARBIN UNIVERSITY OF COMMERCE   (China)

Author keywords

Collagen induced arthritis; FGF21; Inflammation; kappa; B; NF ; Oxidative stress; Rheumatoid arthritis

Indexed keywords

CATALASE; DEXAMETHASONE; FIBROBLAST GROWTH FACTOR 21; GAMMA INTERFERON; GLUTATHIONE; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA ANTIBODY; MALONALDEHYDE; STROMELYSIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; AUTACOID; BLOCKING ANTIBODY; CYTOKINE; FIBROBLAST GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SPLEEN; SPLEEN CELL; SYMPTOM; THERAPY EFFECT; WESTERN BLOTTING; ANIMAL; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELL CULTURE; COMPARATIVE STUDY; DBA MOUSE; DISEASE COURSE; DRUG EFFECTS; HUMAN; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; MALE; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, BLOCKING; ANTIOXIDANTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; CYTOKINES; DEXAMETHASONE; DISEASE PROGRESSION; FIBROBLAST GROWTH FACTORS; HUMANS; IMMUNOSUPPRESSION; INFLAMMATION MEDIATORS; MALE; MATRIX METALLOPROTEINASE 3; MICE; MICE, INBRED DBA; NF-KAPPA B; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84921845458     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.01.005     Document Type: Article

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