The efficacy and mechanism of apoptosis induction by hypericin-mediated sonodynamic therapy in THP-1 macrophages

International Journal of Nanomedicine

Volumn 10, Issue , 2015, Pages 821-838

  Li, Xuesong ^a   Gao, Lei ^a   Zheng, Longbin ^a   Kou, Jiayuan ^a   Zhu, Xing ^a   Jiang, Yueqing ^a   Zhong, Zhaoyu ^a   Dan, Juhua ^a   Xu, Haobo ^a   Yang, Yang ^a   Li, Hong ^a   Shi, Sa ^a   Cao, Wenwu ^b,c   Zhao, Yajun ^a   Tian, Ye ^a   Yang, Liming ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN INSTITUTE OF TECHNOLOGY   (China)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Atherosclerosis; Hypericin; Mitochondria caspase pathway; Sonodynamic therapy

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID DISODIUM; ACETYLCYSTEINE; BONGKREKIC ACID; CASPASE 3; CASPASE 9; CYCLOSPORIN A DERIVATIVE; CYTOCHROME C; HYPERICIN; MALONALDEHYDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SODIUM AZIDE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; PERYLENE; RADIOSENSITIZING AGENT;

APOPTOSIS; ARTICLE; CANCER CELL LINE; CELL NUCLEUS; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DRUG MECHANISM; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; GOLGI COMPLEX; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LOW ENERGY RADIATION; LYSOSOME; MACROPHAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; PHOTODYNAMIC THERAPY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SONODYNAMIC THERAPY; THP 1 MACROPHAGE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASOUND THERAPY; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; CELL SURVIVAL; DRUG EFFECTS; METABOLISM; PATHOLOGY; RADIATION RESPONSE;

APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASE 9; CELL SURVIVAL; CYTOCHROMES C; CYTOSOL; HUMANS; MACROPHAGES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; PERYLENE; POLY(ADP-RIBOSE) POLYMERASES; RADIATION-SENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; ULTRASONIC THERAPY;

EID: 84921837735     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S75398     Document Type: Article

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