Protective effects of caffeic acid phenethyl ester on the dose-dependent acute nephrotoxicity with paraquat in a rat model

Environmental Toxicology

Volumn 30, Issue 3, 2015, Pages 375-381

  Rifaioglu, Murat Mehmet ^a   Sefil, Fatih ^a   Gokce, Hasan ^a   Nacar, Ahmet ^a   Dorum, Bayram Ali ^b   Davarci, Mursel ^a  

^a MUSTAFA KEMAL UNIVERSITY   (Turkey)

^b Sevket Yilmaz Training and Research Hospital   (Turkey)

Author keywords

Caffeic acid phenethyl ester; CAPE; Kidney; Paraquat; Rat

Indexed keywords

ESTERS; HERBICIDES; RATING;

CAFFEIC ACID PHENETHYL ESTER; CAPE; INTRAPERITONEALLY; KIDNEY; NEPHROTOXICITY; PARAQUAT; PROTECTIVE EFFECTS; TOTAL ANTIOXIDANT STATUS;

RATS;

CAFFEIC ACID PHENETHYL ESTER; PARAQUAT; ANTIOXIDANT; CAFFEIC ACID DERIVATIVE; HERBICIDE; PHENETHYL ALCOHOL;

ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GLOMERULUS; HISTOLOGY; KIDNEY STRUCTURE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RENAL PROTECTION; STATISTICAL SIGNIFICANCE; TISSUE DEGENERATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; HUMAN; KIDNEY; KIDNEY DISEASES; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; WISTAR RAT;

RATTUS; TOSCANA VIRUS;

ANIMALS; ANTIOXIDANTS; CAFFEIC ACIDS; FEMALE; HERBICIDES; HUMANS; KIDNEY; KIDNEY DISEASES; OXIDATION-REDUCTION; PARAQUAT; PHENYLETHYL ALCOHOL; RATS; RATS, WISTAR;

EID: 84921822503     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21915     Document Type: Article

References (28)

1. Adachi J, Tomita M, Yamakawa S, Asano M, Naito T, Ueno Y. 2000. 7-hydroperoxycholesterol as a marker of oxidative stress in rat kidney induced by paraquat. Free Radic Res 33:321-327.
2. Afzali S, Gholyaf M. 2008. The effectiveness of combined treatment with methylprednisolone and cyclophosphamide in oral paraquat poisoning. Arch Iran Med 11:387-391.
3. Autor AP. 1974. Reduction of paraquat toxicity by superoxide dismutase. Life Sci 14:1309-1319.
4. Awadalla EA. 2012. Efficacy of vitamin C against liver and kidney damage induced by paraquat toxicity. Exp Toxicol Pathol 64:431-434.
5. Bagley AC, Krall J, Lynch RE. 1986. Superoxide mediates the toxicity of paraquat for Chinese hamster ovary cells. Proc Natl Acad Sci USA 83:3189-3193.
6. Dinis-Oliveira RJ, Duarte JA, Remiao F, Sanchez-Navarro A, Bastos ML, Carvalho F. 2006. Single high dose dexamethasone treatment decreases the pathological score and increases the survival rate of paraquat-intoxicated rats. Toxicology 227:73-85.
7. Dinis-Oliveira RJ, Pontes H, Bastos ML, Remiao F, Duarte JA, Carvalho F. 2009. An effective antidote for paraquat poisonings: The treatment with lysine acetylsalicylate. Toxicology 255:187-193.
8. Fisher AE, Hague TA, Clarke CL, Naughton DP. 2004. Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochem Biophys Res Commun 323:163-167.
9. Garcia-Rubio L, Matas P, Miguez MP. 2005. Protective effect of melatonin on paraquat-induced cytotoxicity in isolated rat hepatocytes. Hum Exp Toxicol 24:475-480.
10. Kegley S, Hill B, Orme S. 2007. PAN Pesticide Database, Pesticide Action Network, North America. Available at: http://www.pesticideinfo.org/Detail_ChemReg.jsp?Rec_Id=PC33744. Accessed October 14, 2010.
11. Koksel O, Ozdulger A, Tamer L, Cinel L, Ercil M, Degirmenci U, Unlu S, Kanik A. 2006. Effects of caffeic acid phenethyl ester on lipopolysaccharide-induced lung injury in rats. Pulm Pharmacol Ther 19:90-95.
12. Krall J, Bagley AC, Mullenbach GT, Hallewell RA, Lynch RE. 1988. Superoxide mediates the toxicity of paraquat for cultured mammalian cells. J Biol Chem 263:1910-1914.
13. Molck AM, Friis C. 1997. The cytotoxic effect of paraquat to isolated renal proximal tubular segments from rabbits. Toxicology 122:123-132.
14. Moon JM, Chun BJ. 2011. The efficacy of high doses of vitamin C in patients with paraquat poisoning. Hum Exp Toxicol 30:844-850.
15. Piotrowski WJ, Pietras T, Kurmanowska Z, Nowak D, Marczak J, Marks-Konczalik J, Mazerant P. 1996. Effect of paraquat intoxication and ambroxol treatment on hydrogen peroxide production and lipid peroxidation in selected organs of rat. J Appl Toxicol 16:501-507.
16. Sabzghabaee AM, Eizadi-Mood N, Montazeri K, Yaraghi A, Golabi M. 2010. Fatality in paraquat poisoning. Singapore Med J 51:496-500.
17. Samai M, Hague T, Naughton DP, Gard PR, Chatterjee PK. 2008. Reduction of paraquat-induced renal cytotoxicity by manganese and copper complexes of EGTA and EHPG. Free Radic Biol Med 44:711-721.
18. Schoenberger CI, Rennard SI, Bitterman PB, Fukuda Y, Ferrans VJ, Crystal RG. 1984. Paraquat-induced pulmonary fibrosis. Role of the alveolitis in modulating the development of fibrosis. Am Rev Respir Dis 129:168-173.
19. Senator A, Rachidi W, Lehmann S, Favier A, Benboubetra M. 2004. Prion protein protects against DNA damage induced by paraquat in cultured cells. Free Radic Biol Med 37:1224-1230.
20. Sittipunt C. 2005. Paraquat poisoning. Respir Care 50:383-385.
21. Suntres ZE. 2002. Role of antioxidants in paraquat toxicity. Toxicology 180:65-77.
22. Tomita M, Okuyama T, Hidaka K. 1999. Changes in mRNAs of inducible nitric oxide synthase and interleukin-1 beta in the liver, kidney and lung tissues of rats acutely exposed to paraquat. Leg Med (Tokyo) 1:127-134.
23. Tutanc M, Arica V, Yilmaz N, Nacar A, Zararsiz I, Basarslan F, Tutanc OD, Nacar E. 2012. Effects of erdosteine on cyclosporin-A-induced nephrotoxicity. Hum Exp Toxicol 31:565-573.
24. Vale JA, Meredith TJ, Buckley BM. 1987. Paraquat poisoning: Clinical features and immediate general management. Hum Toxicol 6:41-47.
25. Wasserman B, Block ER. 1978. Prevention of acute paraquat toxicity in rats by superoxide dismutase. Aviat Space Environ Med 49:805-809.
26. Yilmaz HR, Uz E, Yucel N, Altuntas I, Ozcelik N. 2004. Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver. J Biochem Mol Toxicol 18:234-238.
27. Yoon SP, Han MS, Kim JW, Chang IY, Kim HL, Chung JH, Shin BC. 2011. Protective effects of chitosan oligosaccharide on paraquat-induced nephrotoxicity in rats. Food Chem Toxicol 49:1828-1833.
28. Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ. 1999. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol 154:1423-1429.