Efficacy of vitamin C against liver and kidney damage induced by paraquat toxicity

Experimental and Toxicologic Pathology

Volumn 64, Issue 5, 2012, Pages 431-434

  Awadalla, Eatemad A ^a  

^a ASWAN UNIVERSITY   (Egypt)

Author keywords

Kidney; Liver; Paraquat; Vitamin C

Indexed keywords

ASCORBIC ACID; PARAQUAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; HISTOPATHOLOGY; KIDNEY INJURY; KIDNEY STRUCTURE; LIVER INJURY; LIVER STRUCTURE; MALE; NONHUMAN; RAT; TREATMENT RESPONSE; VITAMIN SUPPLEMENTATION;

ANIMALS; ASCORBIC ACID; HERBICIDES; KIDNEY; LIVER; MALE; PARAQUAT; RATS; VITAMINS;

ANIMALIA; RATTUS;

EID: 84860438489     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2010.10.009     Document Type: Article

References (47)

1. Autor A.P. Biochemical mechanisms of paraquat toxicity 1977, Academic Press, New York.
2. Bateman D.N. Pharmacological treatments of paraquat poisoning. Hum Toxicol 1987, 6:57-62.
3. Bismuth C., Granier R., Baud F.J., Muszynski J., Keyes C. Paraqut poisoning. An over-view of the current status. Drug Safety 1990, 5:243-251.
4. Bismuth C., Garnier R., Dally S., Fournier P.E., Scherrmann J.M. Prognosis and treatment of paraquat poisoning. J Toxicol Clin 1982, 19:461-474.
5. Bullivant C.M. Accidental poisoning by paraquat. Report of two cases in man. Brit Med J 1966, 1:1272-1273.
6. Burk R.F., Lawrence R.A., Lane J.M. Liver necrosis and lipid peroxidation in the rat as the result of paraquat and diquat administration. J Clin Invest 1980, 65:1024-1031.
7. Burton G.W. Vitamin E molecular and biological function. Proc Nutr Soc 1994, 53:251-262.
8. Bus J.S., Gibson J.E. Paraquat model for oxidant initiated toxicity. Environ Health Perspect 1984, 55:37-46.
9. Bus J.S., Aust S.D., Gibson J.E. Paraquat toxicity proposed mechanism of action involving lipid peroxidation. Envir Health Perspect 1976, 16:139-146.
10. Cagen S.Z., Gibson J.E. Liver damage following paraquat in selenium-deficient and diethyl maleatepretreated mice. Toxicol Appl Pharmacol 1977, 40:193-200.
11. Campbell S. Paraquat poisoning. Clin Toxicol 1968, 1:245-249.
12. Carr A., Frei B. Does vitamin C acts as a ro-oxidant under physiological conditions?. FASEB J 1999, 13:1007-1024.
13. Combs G.F., Paterson F.J. Protection against acute paraquat toxicity by dietary selenium in the chick. J Nut 1983, 113:538-545.
14. Comporti M. Three models of free radical induced cell injury. Chem Biol Interact 1989, 72:1-56.
15. Copland G.M., Kolin A., Shulman H.S. Fatal pulmonary intra-alveolar fibrosis after paraquat ingestion. New Engl J Med 1974, 291:290-292.
16. Davies D.S., Hawksworth G.M., Bennett P.N. Paraquat poisoning. Proc Eur Soc Toxicol 1977, 18:21-26.
17. Dodge A.D. The mode of action of the bipyridylium herbicides,paraquat and diquat. Endeavour 1971, 30:130-135.
18. Evans P., Halliwell B. Micronutrients oxidant, antioxidant status. Br J Nutr 2001, 85:67-74.
19. Fisher H.K., Clements J.A., Wright R.R. Enhancement of oxygen toxicity by the herbicide paraquat. Am Rev Respir Dis 1973, 107:246-252.
20. Fitzgerald G.R., Barniville G., Flanagan M., Silke B., Carmody M., Odwyer W.F. The changing pattern of paraquat poisoning: an epidemiologic study. J Ir Med Assoc 1978, 71:103-108.
21. Gabe M. Histological techniques 1976, Springer-Verlag/Masson, New York Heidelberg Berlin/Paris New York Barcelone Milan.
22. Gram T.E. Chemically reactive intermediates and pulmonary xenobiotic toxicity. Pharmacol Rev 1997, 49:297-341.
23. Haley T.J. Review of the toxicology of paraquat. Clin Pharmacol 1979, 14:1-19.
24. Halliwell B. Vitamin C antioxidant or pro-oxidant in vivo. Free Rad. Res 1996, 25:439-454.
25. Halliwell B. Free radicals, antioxidants and human disease. Lancet 1994, 344:721-724.
26. Halliwell B., Murcia M.A., Chiroco S., Aruoma O.I. Free radicals and antioxidants in food and in vivo: what they do and how they work. Crit Rev Food Sci Nut 1995, 35:7-20.
27. Hirai K.I., Witschi H., Cote M.G. Mitochondrial injury of pulmonary alveolar epithelial cells in acute paraquat intoxication. Exp Mol Pathol 1985, 43:242-245.
28. Hong S.Y., Hwang K.Y., Lee E.Y., Eun S.W., Cho S.R., Han C.S., et al. Effect of vitamin C on plasma total antioxidant in patient with paraquat intoxication. Toxicol Let 2000, 126(1):51-59.
29. Jones D.P., Kagan V.E., Aust S.D., Reed D.J., Omaye S.T. Impact of nutrients on cellular lipid peroxidation and antioxidant defence system. Fundam Appl Toxicol 1995, 26:1-7.
30. Honore P., Hantson P., Fauville J.P., Peeters A, Manieu P Paraquat poisoning state of the Art. Acta Clin Belg 1994, 49:220-228.
31. Juchau M.R., Fantel A.G., Harris C., Beyer B.K. The potential role of redox cycling as mechanism for chemical teratogenesis. Environ Health Perspect 1986, 60:131.
32. Kappus H. Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling. Biochem Pharmacol 1986, 35:1-6.
33. Kimbrough R.D., Gaines T.B. Toxicity of paraquat to rats and its effect on rat lungs. Toxicol Appl Pharmacol 1970, 17:679-690.
34. Koo J.R., Kim J.C., Yoon J.W., Kim G.H., Jeon R.W., Kim H.J., et al. Failure of continuous venovenous hemofiltration to prevent death in paraquat poisoning. Am J Kidney Dis 2002, 39:55-59.
35. Margolis A.M., Porasuphatana S., Rosen G.M. Role of paraquat in the coupling of nitric oxide synthase. Biochim Biophys Acta 2000, 1524:253-257.
36. Nermery B., Smith L.L., Aldidge W.N. Putrescine and 5-hydroxytryptamine accumulation in rat lung slices cellular localization and responses to cell specific lung injury. Toxicol Appl Pharmacol 1987, 91:107-120.
37. Padayatty S.J., Katz A., Wang Y., Eck P., Kwon O., Lee J.H., et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr 2003, 22(1):18-35.
38. Pasi A. The toxicology of paraquat, diquat and morphamquat 1978, Hans Huber, Bern Switzerland, 230-244.
39. Reiter R.J. Oxidative damage in the central nervous system protection by melatonin. Prog Neurobiol 1998, 56(3):359-384.
40. Rivero C.E., Martinez E., Gonzalez O.B., Espinoza R., Ramirez M.S. Paraquat poisoning in children: survival of three cases. Vet Hum Toxicol 1992, 34:164-165.
41. Sakr S.A., El-Mofty M.M., Agamy E.I., Okdah Y.A. Electron microscopic study on the effect of the herbicide " paraquat" on the ileum of albino rat. J Egypt Germ Soc Zool 1999, 30:173-180.
42. Smith P., Heah D., Paraquat CRC Crit Rev Toxicol 1976, 4:411-445.
43. Tampo Y., Tsukamoto M., Yonaha M. Superoxide production from paraquat evoked by exogenous NADPH in pulmonary endothelial cells. Free Radic Biol Med 1999, 27:588-595.
44. Tortorelli M.C., Hernandez D.A., Vazquez G.R., Salibian A. Effects of paraquat on mortality and cardiorespiratory function of catfish fry Plecostomus commersoni. Arch Environ Contam Toxicol 1990, 19:523-529.
45. Vale J.A., Meredith T.J., Buckley B.M. Paraquat poisoning: clinical features and immediate general management. Human Toxicol 1987, 6:41-47.
46. Witting L.A. Vitamin E and Lipid antioxidants in free radical initiated reactions. Free Radicals in Biology 1980, IV:295-319.
47. Wyatt I., Soames A.R., Clay M.F., Smith L.L. The accumulation and localization of putrescine, spermidine, and paraquat in the rat lung. In vitro and in vivo studies. Biochem Pharmacol 1988, 37:1909-1918.