The carotid body and its relevance in pathophysiology

Experimental Physiology

Volumn 100, Issue 2, 2015, Pages 121-123

  Del Rio, Rodrigo ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; KRUPPEL LIKE FACTOR 2;

ARRHYTHMOGENESIS; BREATHING PATTERN; CARDIOVASCULAR EFFECT; CAROTID BODY; CAROTID BODY CHEMORECEPTOR; CHEMORECEPTOR REFLEX; CHEMOSENSITIVITY; CHRONIC INTERMITTENT HYPOXIA; EDITORIAL; HEART FAILURE; HEART FUNCTION; HUMAN; HYPERTENSION; NONHUMAN; OXIDATIVE STRESS; OXYGEN TENSION; PATHOPHYSIOLOGY; SLEEP DISORDERED BREATHING; SYMPATHETIC TONE; ANOXIA; BREATHING; PATHOLOGY; PHYSIOLOGY; REFLEX;

ANOXIA; CAROTID BODY; HEART FAILURE; HUMANS; REFLEX; RESPIRATION;

EID: 84921815120     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2014.079350     Document Type: Editorial

References (10)

1. Abdala AP, McBryde FD, Marina N, Hendy EB, Engelman ZJ, Fudim M, Sobotka PA, Gourine AV & Paton JFR (2012). Hypertension is critically dependent on the carotid body input in the spontaneously hypertensive rat. J Physiol 590, 4269-4277.
2. Del Rio R, Andrade DC, Marcus NJ & Schultz HD (2015). Selective carotid body ablation in experimental heart failure: a new therapeutic tool to improve cardiorespiratory control. Exp Physiol 100, 136-142.
3. Gonzalez C, Almaraz L, Obeso A & Rigual R (1991). Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol Rev 74, 829-98.
4. Iturriaga R, Moya EA & Del Rio R (2015). Inflammation and oxidative stress during intermittent hypoxia: the impact on chemoreception. Exp Physiol 100, 149-155.
5. Mansukhani MP, Wang S & Somers VK (2015). Chemoreflex physiology and implications for sleep apnoea: insights from studies in humans. Exp Physiol 100, 130-135.
6. Marcus NJ, Del Rio R, Schultz EP, Xia XH & Schultz HD (2014). Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure. J Physiol 592, 391-408.
7. Paton JFR, Sobotka PA, Fudim M, Engelman ZJ, Hart EC, McBryde FD, Abdala AP, Marina N, Gourine AV, Lobo M, Patel N, Burchell A, Ratcliffe L & Nightingale A (2013). The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases. Hypertension 61, 5-13.
8. Schultz HD, Marcus NJ & Del Rio R (2015). Mechanisms of carotid body chemoreflex dysfunction during heart failure. Exp Physiol 100, 124-129.
9. Somers VK, Mark AL & Abboud FM (1988). Potentiation of the sympathetic nerve responses to hypoxia in borderline hypertensive subjects. Hypertension 11, 608-612.
10. Zoccal DB (2015). Peripheral chemoreceptors and cardiorespiratory coupling: a link to sympatho-excitation. Exp Physiol 100, 143-148.