A systematic review of factors influencing older adults' decision to accept or decline cancer treatment

Cancer Treatment Reviews

Volumn 41, Issue 2, 2015, Pages 197-215

  Puts, Martine T E ^a   Tapscott, Brianne ^a   Fitch, Margaret ^a   Howell, Doris ^a,b   Monette, Johanne ^c   Wan Chow Wah, Doreen ^c   Krzyzanowska, Monika ^b   Leighl, Nathasha B ^b   Springall, Elena ^a   Alibhai, Shabbir M ^d  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Aged; Cancer; Geriatric oncology; Treatment preferences; Treatment refusal; Treatment decision making

Indexed keywords

AGED; BREAST CANCER; CANCER PATIENT; CANCER THERAPY; CROSS-SECTIONAL STUDY; DECISION MAKING; DISEASE SEVERITY; GERIATRIC PATIENT; HUMAN; INTERVENTION STUDY; LONGITUDINAL STUDY; OBSERVATIONAL STUDY; PATIENT ATTITUDE; PHYSICIAN; PROSTATE CANCER; QUALITATIVE RESEARCH; REVIEW; STUDY DESIGN; SYSTEMATIC REVIEW (TOPIC); TREATMENT REFUSAL; ADJUVANT THERAPY; ADVERSE EFFECTS; AGE; BREAST NEOPLASMS; COMORBIDITY; ECONOMICS; FEMALE; INTERPERSONAL COMMUNICATION; MALE; NEOPLASMS; PROSTATIC NEOPLASMS; PSYCHOLOGY; STATISTICS AND NUMERICAL DATA; VERY ELDERLY;

ANTINEOPLASTIC AGENT;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CHOICE BEHAVIOR; COMMUNICATION; COMORBIDITY; DECISION MAKING; FEMALE; HUMANS; MALE; NEOPLASMS; PATIENT ACCEPTANCE OF HEALTH CARE; PROSTATIC NEOPLASMS; QUALITATIVE RESEARCH; RADIOTHERAPY, ADJUVANT; TREATMENT REFUSAL;

EID: 84921795891     PISSN: 03057372     EISSN: 15321967     Source Type: Journal    
DOI: 10.1016/j.ctrv.2014.12.010     Document Type: Review

References (73)

1. Smith B.D., Smith G.L., Hurria A., Hortobagyi G.N., Buchholz T.A. Future of cancer incidence in the United States: burdens upon an aging, changing nation. J Clin Oncol 2009, 27:2758-2765.
2. Howlader N., Noone A.M., Krapcho M., Neyman N., Aminou R., Altekruse S.F., et al. SEER cancer statistics review, 1975-2009 2012, National Cancer Institute, Bethesda.
3. Scher K.S., Hurria A. Under-representation of older adults in cancer registration trials: known problem, little progress. J Clin Oncol 2012, 30:2036-2038.
4. Talarico L., Chen G., Pazdur R. Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration. J Clin Oncol 2004, 22:4626-4631.
5. Stewart J.H., Bertoni A.G., Staten J.L., Levine E.A., Gross C.P. Participation in surgical oncology clinical trials: gender-, race/ethnicity-, and age-based disparities. Ann Surg Oncol 2007, 14(12):3328-3334.
6. Velanovich V., Gabel M., Walker E.M., Doyle T.J., O'Bryan R.M., Szymanski W., et al. Causes for the undertreatment of elderly breast cancer patients: tailoring treatments to individual patients. J Am Coll Surg 2002, 194(1):8-13.
7. Ng R., De B.R., Green M.D. Undertreatment of elderly patients with non-small-cell lung cancer. Clin Lung Cancer 2005, 7:168-174.
8. Bouchardy C., Rapiti E., Blagojevic S., Vlastos A.T., Vlastos G. Older female cancer patients: importance, causes, and consequences of undertreatment. J Clin Oncol 2007, 25:1858-1869.
9. Landrum M.B., Keating N.L., Lamont E.B., Bozeman S.R., McNeil B.J. Reasons for underuse of recommended therapies for colorectal and lung cancer in the Veterans Health Administration. Cancer 2012, 118(13):3345-3355.
10. Molina-Garrido M.J., Mora-Rufete A., Guillen-Ponce C. Oral chemotherapy in elderly women with metastatic breast cancer. Anticancer Agents Med Chem 2014, 14:665-672.
11. Foulon V., Schoffski P., Wolter P. Patient adherence to oral anticancer drugs: an emerging issue in modern oncology. Acta Clin Belg 2011, 66:85-96.
12. Banna G.L., Collova E., Gebbia V., Lipari H., Giuffrida P., Cavallaro S., et al. Anticancer oral therapy: emerging related issues. Cancer Treat Rev 2010, 36:595-605.
13. Verbrugghe M., Verhaeghe S., Lauwaert K., Beeckman D., Van H.A. Determinants and associated factors influencing medication adherence and persistence to oral anticancer drugs: a systematic review. Cancer Treat Rev 2013, 39:610-621.
14. Hurria A., Naeim A., Elkin, Limaye S., Grover A., Hudis C.E., et al. Adjuvant treatment recommendations in older women with breast cancer: a survey of oncologists. Crit Rev Oncol Hematol 2007, 61:255-260.
15. Puts M.T.E., Girre V., Monette J., Wolfson C., Monette M., Batist G., et al. Clinical experience of cancer specialists and geriatricians involved in cancer care of older patients: a qualitative study. Crit Rev Oncol Hematol 2010, 74:87-96.
16. Wan-Chow-Wah D., Monette J., Monette M., Sourial N., Retornaz F., Batist G., et al. Difficulties in decision making regarding chemotherapy for older cancer patients: a census of cancer physicians. Crit Rev Oncol Hematol 2011, 78:45-58.
17. Wyld L., Garg D.K., Kumar I.D., Brown H., Reed M.W.R. Stage and treatment variation with age in postmenopausal women with breast cancer: compliance with guidelines. Br J Cancer 2004, 90(8):1486-1491.
18. Yellen S.B., Cella D.F., Leslie W.T. Age and clinical decision making in oncology patients. J Natl Cancer Inst 1994, 86:1766-1770.
19. Verkooijen H.M., Fioretta G.M., Rapiti E., Bonnefoi H., Vlastos G., Kurtz J., et al. Patients' refusal of surgery strongly impairs breast cancer survival. Ann Surg 2005, 242:276-280.
20. Van Leeuwen B.L., Rosenkranz K.M., Feng L.L., Bedrosian I., Hartmann K., Hunt K.K., et al. The effect of under-treatment of breast cancer in women 80years of age and older. Crit Rev Oncol Hematol 2011, 79:315-320.
21. Johnson M. Chemotherapy treatment decision making by professionals and older patients with cancer: a narrative review of the literature. Eur J Cancer Care (Engl) 2012, 21:3-9.
22. Chouliara Z., Kearney N., Stott D., Molassiotis A., Miller M. Perceptions of older people with cancer of information, decision making and treatment: a systematic review of selected literature. Ann Oncol 2004, 15:1596-1602.
23. Strohschein F.J., Bergman H., Carnevale F.A., Loiselle C.G. Patient decision making among older individuals with cancer. Qual Health Res 2011, 21:900-926.
24. Tariman J.D., Berry D.L., Cochrane B., Doorenbos A., Schepp K.G. Physician, patient, and contextual factors affecting treatment decisions in older adults with cancer and models of decision making: a literature review. Oncol Nurs Forum 2012, 39:E70-E83.
25. Pace R., Pluye P., Bartlett G., Macaulay A.C., Salsberg J., Jagosh J., et al. Testing the reliability and efficiency of the pilot Mixed Methods Appraisal Tool (MMAT) for systematic mixed studies review. Int J Nurs Stud 2012, 49:47-53.
26. Sinding C., Wiernikowski J. Treatment decision making and its discontents. Soc Work Health Care 2009, 48(6):614-634.
27. Sinding C., Wiernikowski J., Aronson J. Cancer care from the perspectives of older women. Oncol Nurs Forum 2005, 32(6):1169-1175.
28. Anchisi S., Anchisi A. Going through chemotherapy: an age-revealing process. Bulletin Cancer 2008, 95(FMC Onco):F44-F50.
29. Anchisi A., Anchisi S., Hugentobler V., Luyet V., Pott M. Accepting chemotherapy at the age of 70 and over: between autonomy and ageing. Bull Cancer 2006, 93(4):407-414.
30. Ashley M.S., Daneshmand S. Factors influencing the choice of urinary diversion in patients undergoing radical cystectomy. BJU Int 2010, 106(5):654-657.
31. Cassileth B.R., Soloway M.S., Vogelzang N.J., Schellhammer P.S., Seidmon E.J., Hait H.I., et al. Patients' choice of treatment in stage D prostate cancer. Urology 1989, 33(5 Suppl.):57-62.
32. Chapple A., Ziebland S., Herxheimer A., McPherson A., Shepperd S., Miller R. Is 'watchful waiting' a real choice for men with prostate cancer? A qualitative study. BJU Int 2002, 90(3):257-264.
33. Chouliara Z., Miller M., Stott D., Molassiotis A., Twelves C., Kearney N. Older people with cancer: perceptions and feelings about information, decision-making and treatment - a pilot study. Eur J Oncol Nurs 2004, 8(3):257-261.
34. Ciambrone D. Treatment decision-making among older women with breast cancer. J Women Aging 2006, 18:31-47.
35. Cohen H., Britten N. Who decides about prostate cancer treatment? A qualitative study. Family Pract 2003, 20(6):724-729.
36. Crooks D.L. Older women with breast cancer: new understandings through grounded theory research. Health Care Women Int 2001, 22(1-2):99-114.
37. Cykert S., Dilworth-Anderson P., Monroe M.H., Walker P., McGuire F.R., Corbie-Smith G., et al. Factors associated with decisions to undergo surgery among patients with newly diagnosed early-stage lung cancer. JAMA 2010, 303(23):2368-2376.
38. Cyran E.M., Crane L.A., Palmer L. Physician sex and other factors associated with type of breast cancer surgery in older women. Arch Surg 2001, 136:185-191.
39. Davison B.J., Oliffe J.L., Pickles T., Mroz L. Factors influencing men undertaking active surveillance for the management of low-risk prostate cancer. Oncol Nurs Forum 2009, 36(1):89-96.
40. Denberg T.D., Melhado T.V., Steiner J.F. Patient treatment preferences in localized prostate carcinoma: the influence of emotion, misconception, and anecdote. Cancer 2006, 107(3):620-630.
41. Diefenbach M.A., Dorsey J., Uzzo R.G., Hanks G.E., Greenberg R.E., Horwitz E., et al. Decision-making strategies for patients with localized prostate cancer. Semin Urol Oncol 2002, 20(1):55-62.
42. Docherty A., Brothwell C.P., Symons M. The impact of inadequate knowledge on patient and spouse experience of prostate cancer. Cancer Nurs 2007, 30(1):58-63.
43. Elit L., Charles C., Dimitry S., Tedford-Gold S., Gafni A., Gold I., et al. It's a choice to move forward: women's perceptions about treatment decision making in recurrent ovarian cancer. Psycho-oncology 2010, 19(3):318-325.
44. Gorin M.A., Soloway C.T., Eldefrawy A., Soloway M.S. Factors that influence patient enrollment in active surveillance for low-risk prostate cancer. Urology 2011, 77(3):588-591.
45. Gwede C.K., Pow-Sang J., Seigne J., Heysek R., Helal M., Shade K., et al. Treatment decision-making strategies and influences in patients with localized prostate carcinoma. Cancer 2005, 104(7):1381-1390.
46. Hall J.D., Boyd J.C., Lippert M.C., Theodorescu D. Why patients choose prostatectomy or brachytherapy for localized prostate cancer: results of a descriptive survey. Urology 2003, 61(2):402-407.
47. Hardy C., Penn S., Morris T. Attitudes of prostate cancer patients towards the diagnosis and treatment of their disease: findings from a multinational survey. Curr Med Res Opin 2007, 23:2107-2116.
48. Holmboe E.S., Concato J. Treatment decisions for localized prostate cancer: asking men what's important. J Gen Intern Med 2000, 15(10):694-701.
49. Husain L.S., Collins K., Reed M., Wyld L. Choices in cancer treatment: a qualitative study of the older women's (>70years) perspective. Psycho-oncology 2008, 17(4):410-416.
50. Kreling B., Figueiredo M.I., Sheppard V.L., Mandelblatt J.S. A qualitative study of factors affecting chemotherapy use in older women with breast cancer: barriers, promoters, and implications for intervention. Psychooncology 2006, 15:1065-1076.
51. Lim L., Chao M., Shapiro J., Millar J.L., Kipp D., Rezo A., et al. Long-term outcomes of patients with localized rectal cancer treated with chemoradiation or radiotherapy alone because of medical inoperability or patient refusal. Dis Colon Rectum 2007, 50(12):2032-2039.
52. O'Rourke M.E. Narrowing the options: the process of deciding on prostate cancer treatment. Cancer Invest 1999, 17(5):349-359.
53. Petrisek A.C., Laliberte L.L., Allen S.M., Mor V. The treatment decision-making process: age differences in a sample of women recently diagnosed with nonrecurrent, early-stage breast cancer. Gerontologist 1997, 37(5):598-608.
54. Pieters H.C., Heilemann M.V., Maliski S., Dornig K., Mentes J. Instrumental relating and treatment decision making among older women with early-stage breast cancer. Oncol Nurs Forum 2012, 39:E10-E19.
55. Richert-Boe K.E., Weinmann S., Shapiro J.A., Rybicki B.A., Enger S.M., Van Den Eeden S.K., et al. Racial differences in treatment of early-stage prostate cancer. Urology 2008, 71:1172-1176.
56. Sanders T., Skevington S. Participation as an expression of patient uncertainty: an exploration of bowel cancer consultations. Psycho-oncology 2004, 13(10):675-688.
57. Sandison A.J., Gold D.M., Wright P., Jones P.A. Breast conservation or mastectomy: treatment choice of women aged 70years and older. Br J Surg 1996, 83(7):994-996.
58. Schulman C. Assessing the attitudes to prostate cancer treatment among European male patients. BJU Int 2007, 100(Suppl. 1):6-11.
59. Sharf B.F., Stelljes L.A., Gordon H.S. 'A little bitty spot and I'm a big man': patients' perspectives on refusing diagnosis or treatment for lung cancer. Psychooncology 2005, 14:636-646.
60. Tang J.I., Shakespeare T.P., Lu J.J., et al. Patients' preference for radiotherapy fractionation schedule in the palliation of symptomatic unresectable lung cancer. J Med Imaging Radiat Oncol 2008, 52(5):497-502.
61. Tang S.W., Parker H., Winterbottom L., Chan Y.H., Lee K.M., Wong L.C., et al. Early primary breast cancer in the elderly - pattern of presentation and treatment. Surg Oncol 2011, 20(1):7-12.
62. van Tol-Geerdink J.J., Stalmeier P.F.M., van Lin E.N.J.T., Schimmel E.C., Huizenga H., van Daal W.A.J., et al. Do patients with localized prostate cancer treatment really want more aggressive treatment?. J Clin Oncol 2006, 24(28):4581-4586.
63. Ward-Smith P. Brachytherapy for prostate cancer: the patient's perspective. Urol Nursing 2003, 23(3):213-217.
64. White M.A., Verhoef M.J., Davison B.J., Gunn H., Cooke K. Seeking mind, body and spirit healing-why some men with prostate cancer choose CAM (complementary and alternative medicine) over conventional cancer treatments. Integr Med Insights 2008, 3:1-11.
65. Sanders T., Skevington S. Do bowel cancer patients participate in treatment decision-making? Findings from a qualitative study. Eur J Cancer Care 2003, 12(2):166-175.
66. Legare F., Politi M.C., Drolet R., Desroches S., Stacey D., Bekker H. Training health professionals in shared decision-making: an international environmental scan. Patient Educ Couns 2012, 88:159-169.
67. Pham A.K., Bauer M.T., Balan S. Closing the patient-oncologist communication gap: a review of historic and current efforts. J Cancer Educ 2014, 29:106-113.
68. Rodriguez K.L., Bayliss N.K., Alexander S.C., Jeffreys A.S., Olsen M.K., Pollak K.I., et al. Effect of patient and patient-oncologist relationship characteristics on communication about health-related quality of life. Psychooncology 2011, 20:935-942.
69. Robinson T.M., Alexander S.C., Hays M., Jeffreys A.S., Olsen M.K., Rodriguez K.L., et al. Patient-oncologist communication in advanced cancer: predictors of patient perception of prognosis. Support Care Cancer 2008, 16:1049-1057.
70. Moore P.M., Rivera M.S., Grez A.M., Lawrie T.A. Communication skills training for healthcare professionals working with people who have cancer. Cochrane Database Syst Rev 2013, 3. CD003751.
71. Donelle L., Arocha J.F., Hoffman-Goetz L. Health literacy and numeracy: key factors in cancer risk comprehension. Chronic Dis Can 2008, 29(1):1-8.
72. Brown S.M., Culver J.O., Osann K.E., MacDonald D.J., Sand S., Thornton A.A., et al. Health literacy, numeracy, and interpretation of graphical breast cancer risk estimates. Patient Educ Couns 2011, 83(1):92-98.
73. Amalraj S., Starkweather C., Nguyen C., Naeim A. Health literacy, communication, and treatment decision-making in older cancer patients. Oncology (Williston Park, N.Y.) 2009, 23(4):369-375.