Chemotherapy treatment decision making by professionals and older patients with cancer: A narrative review of the literature

European Journal of Cancer Care

Volumn 21, Issue 1, 2012, Pages 3-9

  Johnson, M ^a  

^a WHIPPS CROSS UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Ageing; Cancer; Chemotherapy; Older adults; Treatment decision making

Indexed keywords

ANTINEOPLASTIC AGENT;

AGED; DECISION MAKING; FEMALE; HUMAN; HUMAN RELATION; INTERPERSONAL COMMUNICATION; MALE; NEOPLASM; QUALITY OF LIFE; REVIEW;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; COMMUNICATION; DECISION MAKING; FEMALE; HUMANS; MALE; NEOPLASMS; PROFESSIONAL-PATIENT RELATIONS; QUALITY OF LIFE;

EID: 84055184903     PISSN: 09615423     EISSN: 13652354     Source Type: Journal    
DOI: 10.1111/j.1365-2354.2011.01294.x     Document Type: Review

References (42)

1. Amalraj A., Starkweather C. & Naeim A. (2009) Health literacy, communication and treatment decision-making in older cancer patients. Oncology 23, 369-375.
2. Bailey C., Corner J., Addington-Hall J., Kumar D., Nelson M. & Haviland J. (2003) Treatment decisions in older patients with colorectal cancer: the role of age and multidimensional function. European Journal of Cancer Care 12, 257-262.
3. Balducci L. (2003) New paradigms for treating elderly patients with cancer, the comprehensive geriatric assessment and guidelines for supportive care. The Journal of Supportive Oncology 1, 30-37.
4. Balducci L. (2007) Aging frailty and chemotherapy. Cancer Control: Journal of the Moffitt Cancer Center 14, 7-12.
5. Balducci L. & Beghe C. (2000) The application of the principles of geriatrics to the management of the older person with cancer. Critical Reviews in Oncology/Hematology 35, 147-154.
6. Balducci L. & Extermann M. (2000) Management of cancer in the older person: a practical approach. The Oncologist 5, 224-237.
7. Biganzoli L., Goldhirsch A., Straehle C., Castiglione-Gertsch M., Therasse P., Aapro M., Minisini A. & Piccart M. (2004) Adjuvant chemotherapy in elderly patients with breast cancer: a survey of the Breast International Group (BIG). Annals of Oncology 15, 207-210.
8. Blows E., de Blas Lop J., Scanlon K., Richardson A. & Ream E. (2011) Information and support for older women with breat cancer. Cancer Nursing Practice 10, 31-37.
9. Chen H., Cantor A., Meyer J., Corcoran M., Grendys E., Cavanaugh D., Antonek S., Camarata A., Haley W., Balducci L. & Extermann M. (2003) Can older cancer patients tolerate chemotherapy? A prospective pilot study. Cancer 97, 1107-1114.
10. Chouliara Z., Miller M., Stott D., Molassiotis A., Twelves C. & Kearney N. (2004a) Older people with cancer: perceptions and feelings about information, decision making and treatment - a pilot study. European Journal of Oncology Nursing 8, 257-261.
11. Chouliara Z., Kearney N., Stott D., Molassiotis A. & Miller M. (2004b) Perceptions of older people with cancer of information, decision making and treatment: a systematic review of the literature. Annals of Oncology 15, 1596-1602.
12. Chrischilles E., Pendergast J., Kahn K., Wallace R., Moga D., Harrington D., Kiefe C., Weeks J., West D., Zafar S. & Fletcher R. (2010) Adverse events amongst the elderly receiving chemotherapy for advanced non-small-cell lung cancer. Journal of Clinical Oncology 28, 620-627.
13. Extermann M., Overcash J., Lyman G., Parr J. & Balducci L. (1998) Comorbidity and functional status are independent in older cancer patients. Journal of Clinical Oncology 16, 1582-1587.
14. Extermann M., Balducci L. & Lyman G. (2000) What threashold for adjuvant therapy in older breast cancer patients? Journal of Clinical Oncology 18, 1709-1717.
15. Fentiman I. (1996) Are the elderly receiving appropriate treatment for cancer? Annals of Oncology 7, 657-658.
16. Fried T. & Bradley E. (2003) What matters to seriously ill older persons making end-of-life treatment decisions? A qualitative study. Journal of Palliative Medicine 6, 237-244.
17. Given B. & Given C. (2008) Older adults and cancer treatment. Cancer 113 (12 Suppl.), 3505-3511.
18. Gomez Portilla A., Marinez de Lecea C., Cendoya I., Olabarria I., Martin E., Magrach L., Romero E., Cortes J., Muriel J., Marquez A. & Kvadatze M. (2008) Prevalencia y tratamiento de la patologia oncologica en el anciano. El reto que se avecina [Prevalence and treament of oncological disease in the older person. The challenge that is getting nearer]. Revista Espanola de Enfermidades Digestivas 100, 706-715.
19. Hensing T., Peterman A., Schell M., Lee J. & Socinski M. (2003) The impact of age on toxicity, response rate, quality of life and survival in patients with advanced, stage IIIB or IV nonsmall cell lung carcinoma treated with carboplatin and paclitaxel. Cancer 98, 779-788.
20. Holmes C. & Muss H. (2003) Diagnosis and treatment of breast cancer in the elderly. CA: A Cancer Journal for Clinicians 53, 227-244.
21. Kahn K., Adams J., Weeks J., Chrischilles E., Schrag D., Ayanian J., Kiefe C., Ganz P., Bhoopalam N., Potosky A., Harrington D. & Fletcher R. (2010) Adjuvant chemotherapy use and adverse events among older patients with stage III colon cancer. JAMA: The Journal of the American Medical Association 303, 1037-1045.
22. Kearney N., Miller M., Paul J. & Smith K. (2000) Oncology healthcare professionals' attitudes towards elderly people. Annals of Oncology 11, 599-601.
23. Koroukian S., Xu F.B., Diaz-Insua M., Phillips Towe T. & Owusu C. (2010) Comorbidities, functional limitations, and geriatric syndromes in relation to treatment and survival patterns among elders with colorectal cancer. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 65A, 322-329.
24. Lemmens V., van Halteren A., Janssen-Heijnen M., Vreugdenhil G., Repelaer van Driel O. & Coebergh J. (2005) Adjuvant treatment for elderly patients with stage III colon cancer in southern Netherlands is affected by socioeconomic status, gender and comorbidity. Annals of Oncology 16, 767-772.
25. Luciani A., Ascione G., Bertuzzi C., Marussi D., Codeca C., Di Maria G., Caidiera S., Floriani I., Zonato S., Ferrari D. & Foa P. (2010) Detecting disbailities in older patients with cancer: comparison between Comprehensive Geriatric Assessment and Vulnerable Elders Survey-13. Journal of Clinical Oncology 28, 2046-2050.
26. Mandelblatt J., Kreling B., Figeuriedo M. & Feng S. (2006) What is the impact of shared decision making on treatment and outcomes for older women with breast cancer? Journal of Clinical Oncology 24, 4908-4913.
27. Mitry E. & Rougier P. (2008) Review article: benefits and risks of chemotherapy in elderly patients with metastatic colorectal cancer. Alimentary Pharmacology and Therapeutics 29, 161-171.
28. Muss H., Biganzoli L., Sargent D. & Aapro M. (2007) Adjuvant therapy in the elderly: making the right decision. Journal of Clinical Oncology 25, 1870-1875.
29. Neugut A., Fleischauer A., Sundararajan V., Mitra N., Heitjan D., Jacobson J. & Grann V. (2002) Use of adjuvant chemotherapy and radiation therapy for rectal cancer among the elderly: a population-based study. Journal of Clinical Oncology 20, 2643-2650.
30. O'Connor S. (2010) Continuing disparities in survival rates between younger and older cancer patients in Europe. Might oral chemotherapy provide one solution to the problem? European Journal of Cancer Care 19, 421-423.
31. O'Connor S. (2011) Prevention is better than cure and collaboration is better than insularity: reasons why oncologists should embrace the international, public health and care of the elderly agendas in thier research activities. European Journal of Cancer Care 20, 283-285.
32. Office for National Statistics (2010) Statistical Bulletin: Older People's Day 2010. Available at: (retrieved 10 June 2011).
33. Porock D., Cheung K., Morgan D., Winterbottom L., Richardson H. & Ellis I. (2009) Care of older women with breast cancer: a sign of the times? European Journal of Cancer Care 18, 527-529.
34. Quaglia A., Tavilla A., Shack L., Brenner H., Janssen-Heijnen M., Allermani C., Colonna M., Grande E., Grosclaude P., Vercelli M. & the EUROCARE Working Group (2009) The cancer survival gap between elderly and middle-aged patients in Europe is widening. European journal of Cancer 45, 1006-1016.
35. de Rijke J., Schouten L., ten Velde G., Wanders S., Bollen E., Lalisang R., van Dijk J., Kramer G. & van den Brandt P. (2004) Influence of age, comorbidity and performance status on the choice of treatment for patients with non-small cell lung cancer; results of a population based study. Lung Cancer (Amsterdam, Netherlands) 46, 233-245.
36. Sinding C., Wiernikowski J. & Aronson J. (2005) Cancer care from the perspectives of older women. Oncology Nursing Forum 32, 1169-1175.
37. Trask P., Blank T. & Jacobson P. (2008) Future prespectives on the treatment issues associated with cancer and aging. Cancer 113 (12 Suppl.), 3512-3518.
38. Turner N., Haward R., Mulley G. & Selby P. (1999) Cancer in old age - is it adequately investigated and treated? BMJ (Clinical Research Ed.) 319, 309-312.
39. Wedding U., Honecker F., Bokemeyer C., Pientka L. & Hoffken K. (2007) Tolerance to chemotherapy in elderly patients with cancer. Cancer Control: Journal of the Moffitt Cancer Center 14, 44-56.
40. Wymenga A., Slaets J. & Sleijfer D. (2001) Treatment of cancer in old age, shortcomings and challenges. The Netherlands Journal of Medicine 59, 259-266.
41. Yancik R. & Ries L. (2004) Cancer in older persons: an international issue in an aging world. Seminars in Oncology 31, 128-136.
42. Yancik R., Wesley M., Ries L., Havlik R., Edwards B. & Yates J. (2001) Effect of age and comorbidity in post menopausal breast cancer patients aged 55 years and older. JAMA: The Journal of the American Medical Association 285, 885-892.