-
1
-
-
17444407039
-
Heart malformation is an early response to TCDD in embryonic zebrafish
-
Antkiewicz DS, Burns CG, Carney SA, Peterson RE, Heideman W. 2005. Heart malformation is an early response to TCDD in embryonic zebrafish. Toxicol. Sci. 84: 368-377.
-
(2005)
Toxicol. Sci.
, vol.84
, pp. 368-377
-
-
Antkiewicz, D.S.1
Burns, C.G.2
Carney, S.A.3
Peterson, R.E.4
Heideman, W.5
-
2
-
-
79959990108
-
Zebrafish as a model to study cardiac development and human cardiac disease
-
Bakkers J. 2011. Zebrafish as a model to study cardiac development and human cardiac disease. Cardiovasc. Res. 91: 279-288.
-
(2011)
Cardiovasc. Res.
, vol.91
, pp. 279-288
-
-
Bakkers, J.1
-
3
-
-
35148852007
-
Clinical review: aggressive management and extracorporeal support for drug-induced cardiotoxicity
-
Baud FJ, Megarbane B, Deye N, Leprince P. 2007. Clinical review: aggressive management and extracorporeal support for drug-induced cardiotoxicity. Crit. Care 11: 207.
-
(2007)
Crit. Care
, vol.11
, pp. 207
-
-
Baud, F.J.1
Megarbane, B.2
Deye, N.3
Leprince, P.4
-
4
-
-
0346602694
-
Mutation of weak atrium/atrial myosin heavy chain disrupts atrial function and influences ventricular morphogenesis in zebrafish
-
Berdougo E, Coleman H, Lee DH, Stainier DY, Yelon D. 2003. Mutation of weak atrium/atrial myosin heavy chain disrupts atrial function and influences ventricular morphogenesis in zebrafish. Development 130: 6121-6129.
-
(2003)
Development
, vol.130
, pp. 6121-6129
-
-
Berdougo, E.1
Coleman, H.2
Lee, D.H.3
Stainier, D.Y.4
Yelon, D.5
-
5
-
-
33845647342
-
Adriamycin-induced oxidative mitochondrial cardiotoxicity
-
Berthiaume JM, Wallace KB. 2007. Adriamycin-induced oxidative mitochondrial cardiotoxicity. Cell Biol. Toxicol. 23: 15-25.
-
(2007)
Cell Biol. Toxicol.
, vol.23
, pp. 15-25
-
-
Berthiaume, J.M.1
Wallace, K.B.2
-
6
-
-
33746238115
-
Aryl hydrocarbon receptor activation produces heart-specific transcriptional and toxic responses in developing zebrafish
-
Carney SA, Chen J, Burns CG, Xiong KM, Peterson RE, Heideman W. 2006. Aryl hydrocarbon receptor activation produces heart-specific transcriptional and toxic responses in developing zebrafish. Mol. Pharmacol. 70: 549-561.
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 549-561
-
-
Carney, S.A.1
Chen, J.2
Burns, C.G.3
Xiong, K.M.4
Peterson, R.E.5
Heideman, W.6
-
7
-
-
43049108460
-
Comparative genomics identifies genes mediating cardiotoxicity in the embryonic zebrafish heart
-
Chen J, Carney SA, Peterson RE, Heideman W. 2008. Comparative genomics identifies genes mediating cardiotoxicity in the embryonic zebrafish heart. Physiol. Genomics 33: 148-158.
-
(2008)
Physiol. Genomics
, vol.33
, pp. 148-158
-
-
Chen, J.1
Carney, S.A.2
Peterson, R.E.3
Heideman, W.4
-
8
-
-
84862799079
-
The toxic effect of Amiodarone on valve formation in the developing heart of zebrafish embryos
-
Chen YH, Lee HC, Hsu RJ, Chen TY, Huang YK, Lo HC, Hu SC, Harn HJ, Jeng JR, Sun CK, Lin SZ, Tsai HJ. 2012. The toxic effect of Amiodarone on valve formation in the developing heart of zebrafish embryos. Reprod. Toxicol. 33: 233-244.
-
(2012)
Reprod. Toxicol.
, vol.33
, pp. 233-244
-
-
Chen, Y.H.1
Lee, H.C.2
Hsu, R.J.3
Chen, T.Y.4
Huang, Y.K.5
Lo, H.C.6
Hu, S.C.7
Harn, H.J.8
Jeng, J.R.9
Sun, C.K.10
Lin, S.Z.11
Tsai, H.J.12
-
9
-
-
79953668499
-
What has polar surface area ever done for drug discovery?
-
Clark DE. 2011. What has polar surface area ever done for drug discovery? Future Med. Chem. 3: 469-484.
-
(2011)
Future Med. Chem.
, vol.3
, pp. 469-484
-
-
Clark, D.E.1
-
10
-
-
0034609833
-
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties
-
Ertl P, Rohde B, Selzer P. 2000. Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. J. Med. Chem. 43: 3714-3717.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 3714-3717
-
-
Ertl, P.1
Rohde, B.2
Selzer, P.3
-
11
-
-
79952981826
-
A thorough benchmark of density functional methods for general main group thermochemistry, kinetics, and noncovalent interactions
-
Goerigk L, Grimme S. 2011. A thorough benchmark of density functional methods for general main group thermochemistry, kinetics, and noncovalent interactions. Phys. Chem. Chem. Phys. 13: 6670-6688.
-
(2011)
Phys. Chem. Chem. Phys.
, vol.13
, pp. 6670-6688
-
-
Goerigk, L.1
Grimme, S.2
-
12
-
-
84867288643
-
Avogadro: an advanced semantic chemical editor, visualization, and analysis platform
-
Hanwell MD, Curtis DE, Lonie DC, Vandermeersch T, Zurek E, Hutchison GR. 2012. Avogadro: an advanced semantic chemical editor, visualization, and analysis platform. J. Cheminform. 4: 17.
-
(2012)
J. Cheminform.
, vol.4
, pp. 17
-
-
Hanwell, M.D.1
Curtis, D.E.2
Lonie, D.C.3
Vandermeersch, T.4
Zurek, E.5
Hutchison, G.R.6
-
13
-
-
84866168913
-
From omics to drug metabolism and high content screen of natural product in zebrafish: a new model for discovery of neuroactive compound
-
Hung MW, Zhang ZJ, Li S, Lei B, Yuan S, Cui GZ, Man Hoi P, Chan K, Lee SM. 2012. From omics to drug metabolism and high content screen of natural product in zebrafish: a new model for discovery of neuroactive compound. Evid. Based Complement. Alternat. Med. 2012: 605303.
-
(2012)
Evid. Based Complement. Alternat. Med.
, vol.2012
, pp. 605303
-
-
Hung, M.W.1
Zhang, Z.J.2
Li, S.3
Lei, B.4
Yuan, S.5
Cui, G.Z.6
Man Hoi, P.7
Chan, K.8
Lee, S.M.9
-
14
-
-
1842765492
-
Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons
-
Incardona JP, Collier TK, Scholz NL. 2004. Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons. Toxicol. Appl. Pharmacol. 196: 191-205.
-
(2004)
Toxicol. Appl. Pharmacol.
, vol.196
, pp. 191-205
-
-
Incardona, J.P.1
Collier, T.K.2
Scholz, N.L.3
-
16
-
-
67349175359
-
Drug-induced arrhythmias and sudden cardiac death: implications for the pharmaceutical industry
-
Killeen MJ. 2009. Drug-induced arrhythmias and sudden cardiac death: implications for the pharmaceutical industry. Drug Discov. Today 14: 589-597.
-
(2009)
Drug Discov. Today
, vol.14
, pp. 589-597
-
-
Killeen, M.J.1
-
17
-
-
78649346852
-
Constructing a fish metabolic network model
-
Li S, Pozhitkov A, Ryan RA, Manning CS, Brown-Peterson N, Brouwer M. 2010. Constructing a fish metabolic network model. Genome Biol. 11: R115.
-
(2010)
Genome Biol.
, vol.11
, pp. R115
-
-
Li, S.1
Pozhitkov, A.2
Ryan, R.A.3
Manning, C.S.4
Brown-Peterson, N.5
Brouwer, M.6
-
18
-
-
84867393655
-
Advances in zebrafish chemical screening technologies
-
Mathias JR, Saxena MT, Mumm JS. 2012. Advances in zebrafish chemical screening technologies. Future Med. Chem. 4: 1811-1822.
-
(2012)
Future Med. Chem.
, vol.4
, pp. 1811-1822
-
-
Mathias, J.R.1
Saxena, M.T.2
Mumm, J.S.3
-
19
-
-
84858693977
-
Anthracycline cardiotoxicity
-
Menna P, Paz OG, Chello M, Covino E, Salvatorelli E, Minotti G. 2012. Anthracycline cardiotoxicity. Expert Opin. Drug Saf. 11(Suppl. 1): S21-36.
-
(2012)
Expert Opin. Drug Saf.
, vol.11
, pp. S21-S36
-
-
Menna, P.1
Paz, O.G.2
Chello, M.3
Covino, E.4
Salvatorelli, E.5
Minotti, G.6
-
22
-
-
0017712466
-
Nucleic acid binding drugs. Part IV. The crystal structure of the anti-cancer agent daunomycin
-
Neidle S, Taylor G. 1977. Nucleic acid binding drugs. Part IV. The crystal structure of the anti-cancer agent daunomycin. Biochim. Biophys. Acta 479: 450-459.
-
(1977)
Biochim. Biophys. Acta
, vol.479
, pp. 450-459
-
-
Neidle, S.1
Taylor, G.2
-
23
-
-
0025727160
-
Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart
-
Ng WA, Grupp IL, Subramaniam A, Robbins J. 1991. Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart. Circ. Res. 68: 1742-1750.
-
(1991)
Circ. Res.
, vol.68
, pp. 1742-1750
-
-
Ng, W.A.1
Grupp, I.L.2
Subramaniam, A.3
Robbins, J.4
-
24
-
-
35948936011
-
Redundancy and evolution of GATA factor requirements in development of the myocardium
-
Peterkin T, Gibson A, Patient R. 2007. Redundancy and evolution of GATA factor requirements in development of the myocardium. Dev. Biol. 311: 623-635.
-
(2007)
Dev. Biol.
, vol.311
, pp. 623-635
-
-
Peterkin, T.1
Gibson, A.2
Patient, R.3
-
26
-
-
0344309515
-
Development of the model of rat isolated perfused heart for the evaluation of anthracycline cardiotoxicity and its circumvention
-
Pouna P, Bonoron-Adele S, Gouverneur G, Tariosse L, Besse P, Robert J. 1996. Development of the model of rat isolated perfused heart for the evaluation of anthracycline cardiotoxicity and its circumvention. Br. J. Pharmacol. 117: 1593-1599.
-
(1996)
Br. J. Pharmacol.
, vol.117
, pp. 1593-1599
-
-
Pouna, P.1
Bonoron-Adele, S.2
Gouverneur, G.3
Tariosse, L.4
Besse, P.5
Robert, J.6
-
27
-
-
51049106109
-
Anthracycline-induced cardiotoxicity and the cardiac-sparing effect of liposomal formulation
-
Rahman AM, Yusuf SW, Ewer MS. 2007. Anthracycline-induced cardiotoxicity and the cardiac-sparing effect of liposomal formulation. Int. J. Nanomed. 2: 567-583.
-
(2007)
Int. J. Nanomed.
, vol.2
, pp. 567-583
-
-
Rahman, A.M.1
Yusuf, S.W.2
Ewer, M.S.3
-
28
-
-
77249101995
-
Anticancer drugs and cardiotoxicity: Insights and perspectives in the era of targeted therapy
-
Raschi E, Vasina V, Ursino MG, Boriani G, Martoni A, De Ponti F. 2009. Anticancer drugs and cardiotoxicity: Insights and perspectives in the era of targeted therapy. Pharmacol. Ther. 125: 196-218.
-
(2009)
Pharmacol. Ther.
, vol.125
, pp. 196-218
-
-
Raschi, E.1
Vasina, V.2
Ursino, M.G.3
Boriani, G.4
Martoni, A.5
De Ponti, F.6
-
29
-
-
33845600436
-
Preclinical assessment of anthracycline cardiotoxicity in laboratory animals: predictiveness and pitfalls
-
Robert J. 2007. Preclinical assessment of anthracycline cardiotoxicity in laboratory animals: predictiveness and pitfalls. Cell Biol. Toxicol. 23: 27-37.
-
(2007)
Cell Biol. Toxicol.
, vol.23
, pp. 27-37
-
-
Robert, J.1
-
30
-
-
0027787743
-
Pharmacokinetics and metabolism of anthracyclines
-
Robert J, Gianni L. 1993. Pharmacokinetics and metabolism of anthracyclines. Cancer Surv. 17: 219-252.
-
(1993)
Cancer Surv.
, vol.17
, pp. 219-252
-
-
Robert, J.1
Gianni, L.2
-
31
-
-
33746843968
-
Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart
-
Rottbauer W, Wessels G, Dahme T, Just S, Trano N, Hassel D, Burns CG, Katus HA, Fishman MC. 2006. Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart. Circ. Res. 99: 323-331.
-
(2006)
Circ. Res.
, vol.99
, pp. 323-331
-
-
Rottbauer, W.1
Wessels, G.2
Dahme, T.3
Just, S.4
Trano, N.5
Hassel, D.6
Burns, C.G.7
Katus, H.A.8
Fishman, M.C.9
-
32
-
-
77955906955
-
Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection?
-
Sawyer DB, Peng X, Chen B, Pentassuglia L, Lim CC. 2010. Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection? Prog. Cardiovasc. Dis. 53: 105-113.
-
(2010)
Prog. Cardiovasc. Dis.
, vol.53
, pp. 105-113
-
-
Sawyer, D.B.1
Peng, X.2
Chen, B.3
Pentassuglia, L.4
Lim, C.C.5
-
33
-
-
0033963034
-
Molden: a pre- and post-processing program for molecular and electronic structures
-
Schaftenaar G, Noordik JH. 2000. Molden: a pre- and post-processing program for molecular and electronic structures. J. Comput. Aided Mol. Des. 14: 123-134.
-
(2000)
J. Comput. Aided Mol. Des.
, vol.14
, pp. 123-134
-
-
Schaftenaar, G.1
Noordik, J.H.2
-
34
-
-
84864099126
-
The zebrafish has become an attractive model organism in many areas of research ranging from basic developmental biology to applied toxicology
-
Scholz S. 2012. The zebrafish has become an attractive model organism in many areas of research ranging from basic developmental biology to applied toxicology. Reprod. Toxicol. 33: 127.
-
(2012)
Reprod. Toxicol.
, vol.33
, pp. 127
-
-
Scholz, S.1
-
35
-
-
84961974101
-
Calculation of solvent shifts on electronic g-tensors with the conductor-like screening model (COSMO) and its self-consistent generalization to real solvents (direct COSMO-RS)
-
Sinnecker S, Rajendran A, Klamt A, Diedenhofen M, Neese F. 2006. Calculation of solvent shifts on electronic g-tensors with the conductor-like screening model (COSMO) and its self-consistent generalization to real solvents (direct COSMO-RS). J. Phys. Chem. A 110: 2235-2245.
-
(2006)
J. Phys. Chem. A
, vol.110
, pp. 2235-2245
-
-
Sinnecker, S.1
Rajendran, A.2
Klamt, A.3
Diedenhofen, M.4
Neese, F.5
-
36
-
-
38849191869
-
Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells
-
Smith KA, Chocron S, von der Hardt S, de Pater E, Soufan A, Bussmann J, Schulte-Merker S, Hammerschmidt M, Bakkers J. 2008. Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev. Cell 14: 287-297.
-
(2008)
Dev. Cell
, vol.14
, pp. 287-297
-
-
Smith, K.A.1
Chocron, S.2
von der Hardt, S.3
de Pater, E.4
Soufan, A.5
Bussmann, J.6
Schulte-Merker, S.7
Hammerschmidt, M.8
Bakkers, J.9
-
37
-
-
77953931502
-
Cardiotoxicity of anthracycline agents for the treatment of cancer: systematic review and meta-analysis of randomised controlled trials
-
Smith LA, Cornelius VR, Plummer CJ, Levitt G, Verrill M, Canney P, Jones A. 2010. Cardiotoxicity of anthracycline agents for the treatment of cancer: systematic review and meta-analysis of randomised controlled trials. BMC Cancer 10: 337.
-
(2010)
BMC Cancer
, vol.10
, pp. 337
-
-
Smith, L.A.1
Cornelius, V.R.2
Plummer, C.J.3
Levitt, G.4
Verrill, M.5
Canney, P.6
Jones, A.7
-
38
-
-
79955107544
-
Zebrafish for drug toxicity screening: bridging the in vitro cell-based models and in vivo mammalian models
-
Sukardi H, Chng HT, Chan EC, Gong Z, Lam SH. 2011. Zebrafish for drug toxicity screening: bridging the in vitro cell-based models and in vivo mammalian models. Expert Opin. Drug Metab. Toxicol. 7: 579-589.
-
(2011)
Expert Opin. Drug Metab. Toxicol.
, vol.7
, pp. 579-589
-
-
Sukardi, H.1
Chng, H.T.2
Chan, E.C.3
Gong, Z.4
Lam, S.H.5
-
39
-
-
42449149191
-
Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression
-
Sultana N, Nag K, Hoshijima K, Laird DW, Kawakami A, Hirose S. 2008. Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression. Proc. Natl. Acad. Sci. U.S.A. 105: 4763-4768.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 4763-4768
-
-
Sultana, N.1
Nag, K.2
Hoshijima, K.3
Laird, D.W.4
Kawakami, A.5
Hirose, S.6
-
40
-
-
84864296849
-
An in vivo platform for rapid high-throughput antitubercular drug discovery
-
Takaki K, Cosma CL, Troll MA, Ramakrishnan L. 2012. An in vivo platform for rapid high-throughput antitubercular drug discovery. Cell Rep. 2: 175-184.
-
(2012)
Cell Rep.
, vol.2
, pp. 175-184
-
-
Takaki, K.1
Cosma, C.L.2
Troll, M.A.3
Ramakrishnan, L.4
-
41
-
-
53249113134
-
Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number
-
Targoff KL, Schell T, Yelon D. 2008. Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number. Dev. Biol. 322: 314-321.
-
(2008)
Dev. Biol.
, vol.322
, pp. 314-321
-
-
Targoff, K.L.1
Schell, T.2
Yelon, D.3
-
42
-
-
84856773049
-
Cancer survivors in the United States: a review of the literature and a call to action
-
Valdivieso M, Kujawa AM, Jones T, Baker LH. 2012. Cancer survivors in the United States: a review of the literature and a call to action. Int. J. Med. Sci. 9: 163-173.
-
(2012)
Int. J. Med. Sci.
, vol.9
, pp. 163-173
-
-
Valdivieso, M.1
Kujawa, A.M.2
Jones, T.3
Baker, L.H.4
-
44
-
-
33644589017
-
Accurate Coulomb-fitting basis sets for H to Rn
-
Weigend F. 2006. Accurate Coulomb-fitting basis sets for H to Rn. Phys. Chem. Chem. Phys. 8: 1057-1065.
-
(2006)
Phys. Chem. Chem. Phys.
, vol.8
, pp. 1057-1065
-
-
Weigend, F.1
-
45
-
-
26244461462
-
Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy
-
Weigend F, Ahlrichs R. 2005. Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy. Phys. Chem. Chem. Phys. 7: 3297-3305.
-
(2005)
Phys. Chem. Chem. Phys.
, vol.7
, pp. 3297-3305
-
-
Weigend, F.1
Ahlrichs, R.2
-
47
-
-
0032925683
-
Reduction of the cardiotoxicity of doxorubicin in rabbits and dogs by encapsulation in long-circulating, pegylated liposomes
-
Working PK, Newman MS, Sullivan T, Yarrington J. 1999. Reduction of the cardiotoxicity of doxorubicin in rabbits and dogs by encapsulation in long-circulating, pegylated liposomes. J. Pharmacol. Exp. Ther. 289: 1128-1133.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 1128-1133
-
-
Working, P.K.1
Newman, M.S.2
Sullivan, T.3
Yarrington, J.4
-
48
-
-
0035209808
-
Cardiac patterning and morphogenesis in zebrafish
-
Yelon D. 2001. Cardiac patterning and morphogenesis in zebrafish. Dev. Dyn. 222: 552-563.
-
(2001)
Dev. Dyn.
, vol.222
, pp. 552-563
-
-
Yelon, D.1
-
49
-
-
0033215267
-
Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish
-
Yelon D, Horne SA, Stainier DY. 1999. Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish. Dev. Biol. 214: 23-37.
-
(1999)
Dev. Biol.
, vol.214
, pp. 23-37
-
-
Yelon, D.1
Horne, S.A.2
Stainier, D.Y.3
-
50
-
-
84875662361
-
A novel PEGylated liposome-encapsulated SANT75 suppresses tumor growth through inhibiting hedgehog signaling pathway
-
Yuan Y, Zhao Y, Xin S, Wu N, Wen J, Li S, Chen L, Wei Y, Yang H, Lin S. 2013. A novel PEGylated liposome-encapsulated SANT75 suppresses tumor growth through inhibiting hedgehog signaling pathway. PLoS One 8: e60266.
-
(2013)
PLoS One
, vol.8
, pp. e60266
-
-
Yuan, Y.1
Zhao, Y.2
Xin, S.3
Wu, N.4
Wen, J.5
Li, S.6
Chen, L.7
Wei, Y.8
Yang, H.9
Lin, S.10
-
51
-
-
84882649271
-
Toxic effects of cephalosporins with specific functional groups as indicated by zebrafish embryo toxicity testing
-
Zhang J, Qian J, Tong J, Zhang D, Hu C. 2013. Toxic effects of cephalosporins with specific functional groups as indicated by zebrafish embryo toxicity testing. Chem. Res. Toxicol. 26: 1168-1181.
-
(2013)
Chem. Res. Toxicol.
, vol.26
, pp. 1168-1181
-
-
Zhang, J.1
Qian, J.2
Tong, J.3
Zhang, D.4
Hu, C.5
-
52
-
-
22444437609
-
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
-
Zhao Y, Samal E, Srivastava D. 2005. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436: 214-220.
-
(2005)
Nature
, vol.436
, pp. 214-220
-
-
Zhao, Y.1
Samal, E.2
Srivastava, D.3
|