Nanopore-based assay for detection of methylation in double-stranded DNA fragments

ACS Nano

Volumn 9, Issue 1, 2015, Pages 290-300

  Shim, Jiwook ^a   Kim, Younghoon ^a   Humphreys, Gwendolyn I ^b   Nardulli, Ann M ^b   Kosari, Farhad ^c,d   Vasmatzis, George ^c,d   Taylor, William R ^c,d   Ahlquist, David A ^c,d   Myong, Sua ^a   Bashir, Rashid ^a,d  

^a University of Illinois at Urbana Champaign   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c MAYO CLINIC   (United States)

^d Mayo Illinois Alliance for Technology Based Healthcare   (United States)

Author keywords

cancer detection; methyl binding protein; methylated DNA; nanopore; single molecule detection

Indexed keywords

ALKYLATION; ASSAYS; DIAGNOSIS; DISEASES; FUNCTIONAL GROUPS; METHYLATION; MOLECULES; NANOPORES; POLYMERASE CHAIN REACTION; PROTEINS;

BINDING PROTEINS; BIOLOGICAL FLUIDS; CANCER DETECTION; CLINICAL DIAGNOSIS; DOUBLE STRANDED DNA; EPIGENETIC MODIFICATION; METHYLATED DNAS; SINGLE-MOLECULE DETECTION;

DNA;

DNA;

CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CPG ISLAND; DNA METHYLATION; GENETICS; HUMAN; NANOPORE; NANOTECHNOLOGY; PROCEDURES;

CPG ISLANDS; DNA; DNA METHYLATION; HUMANS; MODELS, MOLECULAR; NANOPORES; NANOTECHNOLOGY; NUCLEIC ACID CONFORMATION;

EID: 84921743969     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn5045596     Document Type: Article

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