Post-partum reactivation of chronic hepatitis B virus infection among hepatitis B e-antigen-negative women

World Journal of Gastroenterology

Volumn 21, Issue 4, 2015, Pages 1261-1267

  Elefsiniotis, Ioannis ^a   Vezali, Elena ^a   Vrachatis, Dimitrios ^a   Hatzianastasiou, Sofia ^a   Pappas, Stefanos ^b   Farmakidis, George ^b   Vrioni, Georgia ^c   Tsakris, Athanasios ^c  

^a Elena Venizelou Maternal and Perinatal Hospital   (Greece)

^b General and Maternity Hospital Elena Venizelou   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Hepatitis B; Hepatitis B virus DNA; Post Partum; Pregnancy; Reactivation

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; HEPATITIS B(E) ANTIGEN; VIRUS DNA; ANTIVIRUS AGENT; BIOLOGICAL MARKER;

ADULT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LACTATION; LYMPHOCYTE COUNT; NEUTROPHIL COUNT; OBSERVATIONAL STUDY; PREGNANT WOMAN; PROSPECTIVE STUDY; PUERPERIUM; REAL TIME POLYMERASE CHAIN REACTION; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THIRD TRIMESTER PREGNANCY; VIREMIA; VIRUS REACTIVATION; WEIGHT GAIN; BLOOD; GENETICS; HEPATITIS B, CHRONIC; IMMUNOLOGY; PREGNANCY; RISK FACTOR; TIME FACTOR; VIROLOGY; VIRUS ACTIVATION; VIRUS LOAD; YOUNG ADULT;

ADULT; ANTIVIRAL AGENTS; BIOMARKERS; DNA, VIRAL; FEMALE; HEPATITIS B E ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; POSTPARTUM PERIOD; PREGNANCY; PROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS; VIRAL LOAD; VIRUS ACTIVATION; YOUNG ADULT;

EID: 84921709702     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v21.i4.1261     Document Type: Article

References (26)

1. Alter MJ. Epidemiology and prevention of hepatitis B. Semin Liver Dis 2003; 23: 39-46 [PMID: 12616449 DOI: 10.1055/s-2003-37583]
2. Lavanchy D. Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention. J Clin Virol 2005; 34 Suppl 1: S1-S3 [PMID: 16461208 DOI: 10.1016/S1386-6532(05)00384-7]
3. Piratvisuth T. Optimal management of HBV infection during pregnancy. Liver Int 2013; 33 Suppl 1: 188-194 [PMID: 23286864 DOI: 10.1111/liv.12060]
4. Sinha S, Kumar M. Pregnancy and chronic hepatitis B virus infection. Hepatol Res 2010; 40: 31-48 [PMID: 20156298 DOI: 10.1111/j.1872-034X.2009.00597.x]
5. Bzowej NH. Hepatitis B Therapy in Pregnancy. Curr Hepat Rep 2010; 9: 197-204 [PMID: 20949113 DOI: 10.1007/s11901-010-0059-x]
6. Buchanan C, Tran TT. Management of chronic hepatitis B in pregnancy. Clin Liver Dis 2010; 14: 495-504 [PMID: 20638027 DOI: 10.1016/j.cld.2010.05.008]
7. Shin JI, Namgung R, Park MS, Park KI, Lee C. Immunoprophylaxis failure against vertical transmission of hepatitis B virus: what is the mechanism and do other factors also play a role? Eur J Pediatr 2008; 167: 489-490 [PMID: 17516085 DOI: 10.1007/s00431-007-0499-7]
8. Jonas MM. Hepatitis B and pregnancy: an underestimated issue. Liver Int 2009; 29 Suppl 1: 133-139 [PMID: 19207977 DOI: 10.1111/j.1478-3231.2008.01933.x]
9. Wiseman E, Fraser MA, Holden S, Glass A, Kidson BL, Heron LG, Maley MW, Ayres A, Locarnini SA, Levy MT. Perinatal transmission of hepatitis B virus: an Australian experience. Med J Aust 2009; 190: 489-492 [PMID: 19413519]
10. Elefsiniotis IS, Papadakis M, Vlachos G, Vezali E, Tsoumakas K, Saroglou G, Antsaklis A. Presence of HBV-DNA in cord blood is associated with spontaneous preterm birth in pregnant women with HBeAg-negative chronic hepatitis B virus infection. Intervirology 2011; 54: 300-304 [PMID: 21325782 DOI: 10.1159/000321356]
11. Elefsiniotis IS, Tsoumakas K, Papadakis M, Vlachos G, Saroglou G, Antsaklis A. Importance of maternal and cord blood viremia in pregnant women with chronic hepatitis B virus infection. Eur J Intern Med 2011; 22: 182-186 [PMID: 21402250 DOI: 10.1016/j.ejim.2010.12.005]
12. Bacq Y, Zarka O, Bréchot JF, Mariotte N, Vol S, Tichet J, Weill J. Liver function tests in normal pregnancy: a prospective study of 103 pregnant women and 103 matched controls. Hepatology 1996; 23: 1030-1034 [PMID: 8621129 DOI: 10.1002/hep.510230514]
13. Wakim-Fleming J, Zein NN. The liver in pregnancy: disease vs benign changes. Cleve Clin J Med 2005; 72: 713-721 [PMID: 16122057 DOI: 10.3949/ccjm.72.8.713]
14. Nguyen G, Garcia RT, Nguyen N, Trinh H, Keeffe EB, Nguyen MH. Clinical course of hepatitis B virus infection during pregnancy. Aliment Pharmacol Ther 2009; 29: 755-764 [PMID: 19183158 DOI: 10.1111/j.1365-2036.2009.03932.x]
15. Scherjon S, Lashley L, van der Hoorn ML, Claas F. Fetus specific T cell modulation during fertilization, implantation and pregnancy. Placenta 2011; 32 Suppl 4: S291-S297 [PMID: 21592567 DOI: 10.1016/j.placenta.2011.03.014]
16. Burlingham WJ. A lesson in tolerance-maternal instruction to fetal cells. N Engl J Med 2009; 360: 1355-1357 [PMID: 19321873 DOI: 10.1056/NEJMcibr0810752]
17. Söderström A, Norkrans G, Lindh M. Hepatitis B virus DNA during pregnancy and post partum: aspects on vertical transmission. Scand J Infect Dis 2003; 35: 814-819 [PMID: 14723355 DOI: 10.1080/00365540310016547]
18. Singhal A, Kanagala R, Jalil S, Wright HI, Kohli V. Chronic HBV with pregnancy: reactivation flare causing fulminant hepatic failure. Ann Hepatol 2011; 10: 233-236 [PMID: 21502688]
19. ter Borg MJ, Leemans WF, de Man RA, Janssen HL. Exacerbation of chronic hepatitis B infection after delivery. J Viral Hepat 2008; 15: 37-41 [PMID: 18088243 DOI: 10.1111/j.1365-2893.2007.00894.x]
20. Elefsiniotis IS, Glynou I, Brokalaki H, Magaziotou I, Pantazis KD, Fotiou A, Liosis G, Kada H, Saroglou G. Serological and virological profile of chronic HBV infected women at reproductive age in Greece. A two-year single center study. Eur J Obstet Gynecol Reprod Biol 2007; 132: 200-203 [PMID: 17030083 DOI: 10.1016/j.ejogrb.2006.08.015]
21. Papatheodoridis GV, Manesis EK, Manolakopoulos S, Elefsiniotis IS, Goulis J, Giannousis J, Bilalis A, Kafiri G, Tzourmakliotis D, Archimandritis AJ. Is there a meaningful serum hepatitis B virus DNA cutoff level for therapeutic decisions in hepatitis B e antigen-negative chronic hepatitis B virus infection? Hepatology 2008; 48: 1451-1459 [PMID: 18924246 DOI: 10.1002/hep.22518]
22. Lurie S, Rahamim E, Piper I, Golan A, Sadan O. Total and differential leukocyte counts percentiles in normal pregnancy. Eur J Obstet Gynecol Reprod Biol 2008; 136: 16-19 [PMID: 17275981 DOI: 10.1016/j.ejogrb.2006.12.013]
23. Roehrl MH, Wang JY. Immature granulocytes in pregnancy: a story of Virchow, anxious fathers, and expectant mothers. Am J Hematol 2011; 86: 307-308 [PMID: 20652972 DOI: 10.1002/ajh.21784]
24. Norman JE, Yuan M, Anderson L, Howie F, Harold G, Young A, Jordan F, McInnes I, Harnett MM. Effect of prolonged in vivo administration of progesterone in pregnancy on myometrial gene expression, peripheral blood leukocyte activation, and circulating steroid hormone levels. Reprod Sci 2011; 18: 435-446 [PMID: 21558462 DOI: 10.1177/1933719110395404]
25. Miller EM. Changes in serum immunity during pregnancy. Am J Hum Biol 2009; 21: 401-403 [PMID: 19189417 DOI: 10.1002/ajhb.20882]
26. Rehermann B. Chronic infections with hepatotropic viruses: mechanisms of impairment of cellular immune responses. Semin Liver Dis 2007; 27: 152-160 [PMID: 17520515 DOI: 10.1055/s-2007-979468]