메뉴 건너뛰기




Volumn 33, Issue 2, 2015, Pages 342-353

Nerve growth factor and prongf simultaneously promote symmetric self-renewal, quiescence, and epithelial to mesenchymal transition to enlarge the breast cancer stem cell compartment

Author keywords

Breast cancer stem cells; Nerve growth factor; p75NTR; proNGF

Indexed keywords

NERVE GROWTH FACTOR; NEUROTROPHIN RECEPTOR P75; PRONGF PROTEIN; PROTEIN PRECURSOR; UNCLASSIFIED DRUG; NERVE GROWTH FACTOR RECEPTOR; NERVE PROTEIN; NGF PROTEIN, HUMAN; NGFR PROTEIN, HUMAN; PRO-NERVE GROWTH FACTOR, HUMAN; TUMOR PROTEIN;

EID: 84921695004     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1849     Document Type: Article
Times cited : (51)

References (62)
  • 2
    • 44049100934 scopus 로고    scopus 로고
    • Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
    • Li X, Lewis MT, Huang J, et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 2008; 100: 672-679.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 672-679
    • Li, X.1    Lewis, M.T.2    Huang, J.3
  • 3
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA,. Hallmarks of cancer: The next generation. Cell 2011; 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 36048947234 scopus 로고    scopus 로고
    • Breast cancer: Origins and evolution
    • Polyak K,. Breast cancer: Origins and evolution. J Clin Invest 2007; 117: 3155-3163.
    • (2007) J Clin Invest , vol.117 , pp. 3155-3163
    • Polyak, K.1
  • 5
    • 0033635904 scopus 로고    scopus 로고
    • Neurotrophins: Key regulators of cell fate and cell shape in the vertebrate nervous system
    • Bibel M, Barde YA,. Neurotrophins: Key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev 2000; 14: 2919-2937.
    • (2000) Genes Dev , vol.14 , pp. 2919-2937
    • Bibel, M.1    Barde, Y.A.2
  • 6
    • 0032479287 scopus 로고    scopus 로고
    • Nerve growth factor is mitogenic for cancerous but not normal human breast epithelial cells
    • Descamps S, Lebourhis X, Delehedde M, et al. Nerve growth factor is mitogenic for cancerous but not normal human breast epithelial cells. J Biol Chem 1998; 273: 16659-16662.
    • (1998) J Biol Chem , vol.273 , pp. 16659-16662
    • Descamps, S.1    Lebourhis, X.2    Delehedde, M.3
  • 7
    • 0004594704 scopus 로고    scopus 로고
    • Nerve growth factor stimulates proliferation and survival of human breast cancer cells through two distinct signaling pathways
    • Descamps S, Toillon RA, Adriaenssens E, et al. Nerve growth factor stimulates proliferation and survival of human breast cancer cells through two distinct signaling pathways. J Biol Chem 2001; 276: 17864-17870.
    • (2001) J Biol Chem , vol.276 , pp. 17864-17870
    • Descamps, S.1    Toillon, R.A.2    Adriaenssens, E.3
  • 8
    • 36749055667 scopus 로고    scopus 로고
    • Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis
    • Com E, Lagadec C, Page A, et al. Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis. Mol Cell Proteomics 2007; 6: 1842-1854.
    • (2007) Mol Cell Proteomics , vol.6 , pp. 1842-1854
    • Com, E.1    Lagadec, C.2    Page, A.3
  • 9
    • 39049102137 scopus 로고    scopus 로고
    • Nerve growth factor is a potential therapeutic target in breast cancer
    • Adriaenssens E, Vanhecke E, Saule P, et al. Nerve growth factor is a potential therapeutic target in breast cancer. Cancer Res 2008; 68: 346-351.
    • (2008) Cancer Res , vol.68 , pp. 346-351
    • Adriaenssens, E.1    Vanhecke, E.2    Saule, P.3
  • 10
    • 0029968432 scopus 로고    scopus 로고
    • Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases
    • Seidah NG, Benjannet S, Pareek S, et al. Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases. Biochem J 1996; 314(Pt 3): 951-960.
    • (1996) Biochem J , vol.3143 , pp. 951-960
    • Seidah, N.G.1    Benjannet, S.2    Pareek, S.3
  • 11
    • 0035976524 scopus 로고    scopus 로고
    • Regulation of cell survival by secreted proneurotrophins
    • Lee R, Kermani P, Teng KK, et al. Regulation of cell survival by secreted proneurotrophins. Science 2001; 294: 1945-1948.
    • (2001) Science , vol.294 , pp. 1945-1948
    • Lee, R.1    Kermani, P.2    Teng, K.K.3
  • 12
    • 11144355567 scopus 로고    scopus 로고
    • Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury
    • Harrington AW, Leiner B, Blechschmitt C, et al. Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury. Proc Natl Acad Sci USA 2004; 101: 6226-6230.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6226-6230
    • Harrington, A.W.1    Leiner, B.2    Blechschmitt, C.3
  • 13
    • 84855833498 scopus 로고    scopus 로고
    • Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein
    • Demont Y, Corbet C, Page A, et al. Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein. J Biol Chem 2012; 287: 1923-1931.
    • (2012) J Biol Chem , vol.287 , pp. 1923-1931
    • Demont, Y.1    Corbet, C.2    Page, A.3
  • 14
    • 10744219632 scopus 로고    scopus 로고
    • Sortilin is essential for proNGF-induced neuronal cell death
    • Nykjaer A, Lee R, Teng KK, et al. Sortilin is essential for proNGF-induced neuronal cell death. Nature 2004; 427: 843-848.
    • (2004) Nature , vol.427 , pp. 843-848
    • Nykjaer, A.1    Lee, R.2    Teng, K.K.3
  • 15
    • 78650678063 scopus 로고    scopus 로고
    • Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
    • Vaegter CB, Jansen P, Fjorback AW, et al. Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nat Neurosci 2011; 14: 54-61.
    • (2011) Nat Neurosci , vol.14 , pp. 54-61
    • Vaegter, C.B.1    Jansen, P.2    Fjorback, A.W.3
  • 16
    • 77955280205 scopus 로고    scopus 로고
    • Analysis of early human neural crest development
    • Betters E, Liu Y, Kjaeldgaard A, et al. Analysis of early human neural crest development. Dev Biol 2010; 344: 578-592.
    • (2010) Dev Biol , vol.344 , pp. 578-592
    • Betters, E.1    Liu, Y.2    Kjaeldgaard, A.3
  • 17
    • 84903306561 scopus 로고    scopus 로고
    • Role of p75 neurotrophin receptor in stem cell biology: More than just a marker
    • Tomellini E, Lagadec C, Polakowska R, et al. Role of p75 neurotrophin receptor in stem cell biology: More than just a marker. Cell Mol Life Sci 2014; 71: 2467-2481.
    • (2014) Cell Mol Life Sci , vol.71 , pp. 2467-2481
    • Tomellini, E.1    Lagadec, C.2    Polakowska, R.3
  • 18
    • 79955488579 scopus 로고    scopus 로고
    • CD271/p75(NTR) inhibits the differentiation of mesenchymal stem cells into osteogenic, adipogenic, chondrogenic, and myogenic lineages
    • Mikami Y, Ishii Y, Watanabe N, et al. CD271/p75(NTR) inhibits the differentiation of mesenchymal stem cells into osteogenic, adipogenic, chondrogenic, and myogenic lineages. Stem Cells Dev 2011; 20: 901-913.
    • (2011) Stem Cells Dev , vol.20 , pp. 901-913
    • Mikami, Y.1    Ishii, Y.2    Watanabe, N.3
  • 19
    • 0038001274 scopus 로고    scopus 로고
    • Neurotrophin receptor p75(NTR) characterizes human esophageal keratinocyte stem cells in vitro
    • Okumura T, Shimada Y, Imamura M, et al. Neurotrophin receptor p75(NTR) characterizes human esophageal keratinocyte stem cells in vitro. Oncogene 2003; 22: 4017-4026.
    • (2003) Oncogene , vol.22 , pp. 4017-4026
    • Okumura, T.1    Shimada, Y.2    Imamura, M.3
  • 20
    • 84863143829 scopus 로고    scopus 로고
    • Biological and clinical significance of p75NTR expression in laryngeal squamous epithelia and laryngocarcinoma
    • Li X, Shen Y, Di B, et al. Biological and clinical significance of p75NTR expression in laryngeal squamous epithelia and laryngocarcinoma. Acta Otolaryngol 2012; 132: 314-324.
    • (2012) Acta Otolaryngol , vol.132 , pp. 314-324
    • Li, X.1    Shen, Y.2    Di, B.3
  • 21
    • 33847624256 scopus 로고    scopus 로고
    • Identification of human oral keratinocyte stem/progenitor cells by neurotrophin receptor p75 and the role of neurotrophin/p75 signaling
    • Nakamura T, Endo K, Kinoshita S,. Identification of human oral keratinocyte stem/progenitor cells by neurotrophin receptor p75 and the role of neurotrophin/p75 signaling. Stem Cells 2007; 25: 628-638.
    • (2007) Stem Cells , vol.25 , pp. 628-638
    • Nakamura, T.1    Endo, K.2    Kinoshita, S.3
  • 22
    • 79955828449 scopus 로고    scopus 로고
    • P75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes
    • Truzzi F, Marconi A, Atzei P, et al. p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes. Cell Death Differ 2011; 18: 948-958.
    • (2011) Cell Death Differ , vol.18 , pp. 948-958
    • Truzzi, F.1    Marconi, A.2    Atzei, P.3
  • 23
    • 58149522237 scopus 로고    scopus 로고
    • Localization of the low-affinity nerve growth factor receptor p75 in human limbal epithelial cells
    • Di Girolamo N, Sarris M, Chui J, et al. Localization of the low-affinity nerve growth factor receptor p75 in human limbal epithelial cells. J Cell Mol Med 2008; 12(6B): 2799-2811.
    • (2008) J Cell Mol Med , vol.126 , pp. 2799-2811
    • Di Girolamo, N.1    Sarris, M.2    Chui, J.3
  • 24
    • 84859949726 scopus 로고    scopus 로고
    • Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
    • Kim J, Villadsen R, Sørlie T, et al. Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity. Proc Natl Acad Sci USA 2012; 109: 6124-6129.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 6124-6129
    • Kim, J.1    Villadsen, R.2    Sørlie, T.3
  • 25
    • 84875776236 scopus 로고    scopus 로고
    • The PI3K/AKT signaling pathway controls the quiescence of the low-Rhodamine123-retention cell compartment enriched for melanoma stem cell activity
    • Touil Y, Zuliani T, Wolowczuk I, et al. The PI3K/AKT signaling pathway controls the quiescence of the low-Rhodamine123-retention cell compartment enriched for melanoma stem cell activity. STEM CELLS 2012; 31: 641-651.
    • (2012) STEM CELLS , vol.31 , pp. 641-651
    • Touil, Y.1    Zuliani, T.2    Wolowczuk, I.3
  • 26
    • 84908159714 scopus 로고    scopus 로고
    • Transient TNF regulates the self-renewing capacity of stem-like label-retaining cells in sphere and skin equivalent models of melanoma
    • Ostyn P, El-Machhour R, Begard S, et al. Transient TNF regulates the self-renewing capacity of stem-like label-retaining cells in sphere and skin equivalent models of melanoma. Cell Commun Signal 2014; 12: 52.
    • (2014) Cell Commun Signal , vol.12 , pp. 52
    • Ostyn, P.1    El-Machhour, R.2    Begard, S.3
  • 27
    • 0034999898 scopus 로고    scopus 로고
    • Monitoring metastatic behavior of human tumor cells in mice with species-specific polymerase chain reaction: Elevated expression of angiogenesis and bone resorption stimulators by breast cancer in bone metastases
    • Pluijm G, van der, Sijmons B, Vloedgraven H, et al. Monitoring metastatic behavior of human tumor cells in mice with species-specific polymerase chain reaction: Elevated expression of angiogenesis and bone resorption stimulators by breast cancer in bone metastases. J Bone Miner Res 2001; 16: 1077-1091.
    • (2001) J Bone Miner Res , vol.16 , pp. 1077-1091
    • Pluijm, G.1    Van Der Sijmons, B.2    Vloedgraven, H.3
  • 28
    • 67650504966 scopus 로고    scopus 로고
    • TScratch: A novel and simple software tool for automated analysis of monolayer wound healing assays
    • Gebäck T, Schulz MMP, Koumoutsakos P, et al. TScratch: A novel and simple software tool for automated analysis of monolayer wound healing assays. Biotechniques 2009; 46: 265-274.
    • (2009) Biotechniques , vol.46 , pp. 265-274
    • Gebäck, T.1    Schulz, M.M.P.2    Koumoutsakos, P.3
  • 29
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu G, Abdallah WM, Foley JM, et al. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 2003; 17: 1253-1270.
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3
  • 30
    • 0011478490 scopus 로고
    • Three clonal types of keratinocyte with different capacities for multiplication
    • Barrandon Y, Green H,. Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci USA 1987; 84: 2302-2306.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2302-2306
    • Barrandon, Y.1    Green, H.2
  • 31
    • 67349191354 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase as a marker for stem cells
    • Moreb JS,. Aldehyde dehydrogenase as a marker for stem cells. Curr Stem Cell Res Ther 2008; 3: 237-246.
    • (2008) Curr Stem Cell Res Ther , vol.3 , pp. 237-246
    • Moreb, J.S.1
  • 32
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007; 1: 555-567.
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3
  • 33
    • 67649884727 scopus 로고    scopus 로고
    • Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression
    • Morimoto K, Kim SJ, Tanei T, et al. Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression. Cancer Sci 2009; 100: 1062-1068.
    • (2009) Cancer Sci , vol.100 , pp. 1062-1068
    • Morimoto, K.1    Kim, S.J.2    Tanei, T.3
  • 34
    • 33744519452 scopus 로고    scopus 로고
    • Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase
    • Taurin S, Sandbo N, Qin Y, et al. Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase. J Biol Chem 2006; 281: 9971-9976.
    • (2006) J Biol Chem , vol.281 , pp. 9971-9976
    • Taurin, S.1    Sandbo, N.2    Qin, Y.3
  • 35
    • 84873681862 scopus 로고    scopus 로고
    • The way Wnt works: Components and mechanism
    • Saito-Diaz K, Chen TW, Wang X, et al. The way Wnt works: Components and mechanism. Growth Factors 2013; 31: 1-31.
    • (2013) Growth Factors , vol.31 , pp. 1-31
    • Saito-Diaz, K.1    Chen, T.W.2    Wang, X.3
  • 36
    • 82555191519 scopus 로고    scopus 로고
    • Overexpression of p75(NTR) increases survival of breast cancer cells through p21(waf1)
    • Verbeke S, Meignan S, Lagadec C, et al. Overexpression of p75(NTR) increases survival of breast cancer cells through p21(waf1). Cell Signal 2010; 22: 1864-1873.
    • (2010) Cell Signal , vol.22 , pp. 1864-1873
    • Verbeke, S.1    Meignan, S.2    Lagadec, C.3
  • 37
    • 84881477565 scopus 로고    scopus 로고
    • Extracellular cleavage of the p75 neurotrophin receptor is implicated in its pro-survival effect in breast cancer cells
    • Verbeke S, Tomellini E, Dhamani F, et al. Extracellular cleavage of the p75 neurotrophin receptor is implicated in its pro-survival effect in breast cancer cells. FEBS Lett 2013; 587: 2591-2596.
    • (2013) FEBS Lett , vol.587 , pp. 2591-2596
    • Verbeke, S.1    Tomellini, E.2    Dhamani, F.3
  • 38
    • 84896713066 scopus 로고    scopus 로고
    • Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis
    • Touil Y, Igoudjil W, Corvaisier M, et al. Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis. Clin Cancer Res 2014; 20: 837-846.
    • (2014) Clin Cancer Res , vol.20 , pp. 837-846
    • Touil, Y.1    Igoudjil, W.2    Corvaisier, M.3
  • 39
    • 79953696909 scopus 로고    scopus 로고
    • The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells
    • Che S-M, Zhang X-Z, Liu X-L, et al. The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells. Dis Esophagus 2011; 24: 265-273.
    • (2011) Dis Esophagus , vol.24 , pp. 265-273
    • Che, S.-M.1    Zhang, X.-Z.2    Liu, X.-L.3
  • 40
    • 0347634454 scopus 로고    scopus 로고
    • Defining the epithelial stem cell niche in skin
    • Tumbar T, Guasch G, Greco V, et al. Defining the epithelial stem cell niche in skin. Science 2004; 303: 359-363.
    • (2004) Science , vol.303 , pp. 359-363
    • Tumbar, T.1    Guasch, G.2    Greco, V.3
  • 41
    • 27144510277 scopus 로고    scopus 로고
    • Stem cells, asymmetric division and cancer
    • Clevers H,. Stem cells, asymmetric division and cancer. Nat Genet 2005; 37: 1027-1028.
    • (2005) Nat Genet , vol.37 , pp. 1027-1028
    • Clevers, H.1
  • 42
    • 78649439321 scopus 로고    scopus 로고
    • Asymmetric cell division: Recent developments and their implications for tumour biology
    • Knoblich JA,. Asymmetric cell division: Recent developments and their implications for tumour biology. Nat Rev Mol Cell Biol 2010; 11: 849-860.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 849-860
    • Knoblich, J.A.1
  • 43
    • 84866410772 scopus 로고    scopus 로고
    • Regulation of self-renewal in normal and cancer stem cells
    • Verga Falzacappa MV, Ronchini C, Reavie LB, et al. Regulation of self-renewal in normal and cancer stem cells. FEBS J 2012; 279: 3559-3572.
    • (2012) FEBS J , vol.279 , pp. 3559-3572
    • Verga Falzacappa, M.V.1    Ronchini, C.2    Reavie, L.B.3
  • 44
    • 33745600820 scopus 로고    scopus 로고
    • Asymmetric and symmetric stem-cell divisions in development and cancer
    • Morrison SJ, Kimble J,. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 2006; 441: 1068-1074.
    • (2006) Nature , vol.441 , pp. 1068-1074
    • Morrison, S.J.1    Kimble, J.2
  • 45
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • Pece S, Tosoni D, Confalonieri SM, et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 2010; 140: 62-73.
    • (2010) Cell , vol.140 , pp. 62-73
    • Pece, S.1    Tosoni, D.2    Confalonieri, S.M.3
  • 46
    • 33745600820 scopus 로고    scopus 로고
    • Asymmetric and symmetric stem-cell divisions in development and cancer
    • Morrison SJ, Kimble J,. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature. 2006; 441: 1068-1074.
    • (2006) Nature. , vol.441 , pp. 1068-1074
    • Morrison, S.J.1    Kimble, J.2
  • 47
    • 84867272850 scopus 로고    scopus 로고
    • How to keep proliferative neural stem/progenitor cells: A critical role of asymmetric inheritance of cyclin D2
    • Tsunekawa Y, Osumi N,. How to keep proliferative neural stem/progenitor cells: A critical role of asymmetric inheritance of cyclin D2. Cell Cycle 2012; 11: 3550-3554.
    • (2012) Cell Cycle , vol.11 , pp. 3550-3554
    • Tsunekawa, Y.1    Osumi, N.2
  • 48
    • 84859918676 scopus 로고    scopus 로고
    • Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates
    • Tsunekawa Y, Britto JM, Takahashi M, et al. Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates. EMBO J 2012; 31: 1879-1892.
    • (2012) EMBO J , vol.31 , pp. 1879-1892
    • Tsunekawa, Y.1    Britto, J.M.2    Takahashi, M.3
  • 49
    • 0037388204 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic breast cancer cells
    • Al-Hajj M, Wicha MS, Benito-Hernandez A, et al. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003; 100: 3983-3988.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3983-3988
    • Al-Hajj, M.1    Wicha, M.S.2    Benito-Hernandez, A.3
  • 50
    • 48949119473 scopus 로고    scopus 로고
    • Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
    • Fillmore CM, Kuperwasser C,. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res 2008; 10: R25.
    • (2008) Breast Cancer Res , vol.10 , pp. R25
    • Fillmore, C.M.1    Kuperwasser, C.2
  • 51
    • 84869145479 scopus 로고    scopus 로고
    • Migratory gene expression signature predicts poor patient outcome: Are cancer stem cells to blame?
    • Wicha MS,. Migratory gene expression signature predicts poor patient outcome: Are cancer stem cells to blame? Breast Cancer Res 2012; 14: 114.
    • (2012) Breast Cancer Res , vol.14 , pp. 114
    • Wicha, M.S.1
  • 52
    • 84879983245 scopus 로고    scopus 로고
    • Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
    • Chaffer CL, Marjanovic ND, Lee T, et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 2013; 154: 61-74.
    • (2013) Cell , vol.154 , pp. 61-74
    • Chaffer, C.L.1    Marjanovic, N.D.2    Lee, T.3
  • 53
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao M-J, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.-J.3
  • 54
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RYJ, et al. Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139: 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.J.3
  • 55
    • 0041335562 scopus 로고    scopus 로고
    • Nerve growth factor overexpression and autocrine loop in breast cancer cells
    • Dollé L, El Yazidi-Belkoura I, Adriaenssens E, et al. Nerve growth factor overexpression and autocrine loop in breast cancer cells. Oncogene 2003; 22: 5592-5601.
    • (2003) Oncogene , vol.22 , pp. 5592-5601
    • Dollé, L.1    El Yazidi-Belkoura, I.2    Adriaenssens, E.3
  • 56
    • 7244250027 scopus 로고    scopus 로고
    • Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
    • Pece S, Serresi M, Santolini E, et al. Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J Cell Biol 2004; 167: 215-221.
    • (2004) J Cell Biol , vol.167 , pp. 215-221
    • Pece, S.1    Serresi, M.2    Santolini, E.3
  • 57
    • 77955654410 scopus 로고    scopus 로고
    • Numb protein expression correlates with a basal-like phenotype and cancer stem cell markers in primary breast cancer
    • Rennstam K, McMichael N, Berglund P, et al. Numb protein expression correlates with a basal-like phenotype and cancer stem cell markers in primary breast cancer. Breast Cancer Res Treat 2010; 122: 315-324.
    • (2010) Breast Cancer Res Treat , vol.122 , pp. 315-324
    • Rennstam, K.1    McMichael, N.2    Berglund, P.3
  • 58
    • 84857817163 scopus 로고    scopus 로고
    • Slug and Sox9 cooperatively determine the mammary stem cell state
    • Guo W, Keckesova Z, Donaher JL, et al. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell 2012; 148: 1015-1028.
    • (2012) Cell , vol.148 , pp. 1015-1028
    • Guo, W.1    Keckesova, Z.2    Donaher, J.L.3
  • 59
    • 84881470445 scopus 로고    scopus 로고
    • SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells
    • Herreros-Villanueva M, Zhang J-S, Koenig A, et al. SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells. Oncogenesis 2013; 2: e61.
    • (2013) Oncogenesis , vol.2 , pp. e61
    • Herreros-Villanueva, M.1    Zhang, J.-S.2    Koenig, A.3
  • 60
    • 32944459251 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Roles in cancer and metastasis
    • Fingleton B,. Matrix metalloproteinases: Roles in cancer and metastasis. Front Biosci 2006; 11: 479-491.
    • (2006) Front Biosci , vol.11 , pp. 479-491
    • Fingleton, B.1
  • 61
    • 0030982225 scopus 로고    scopus 로고
    • Pro-protein convertase gene expression in human breast cancer
    • Cheng M, Watson PH, Paterson JA, et al. Pro-protein convertase gene expression in human breast cancer. Int J Cancer 1997; 71: 966-971.
    • (1997) Int J Cancer , vol.71 , pp. 966-971
    • Cheng, M.1    Watson, P.H.2    Paterson, J.A.3
  • 62
    • 33645797766 scopus 로고    scopus 로고
    • Overexpression of the plasminogen activator inhibitor type-1 in epithelial ovarian cancer
    • Koensgen D, Mustea A, Denkert C, et al. Overexpression of the plasminogen activator inhibitor type-1 in epithelial ovarian cancer. Anticancer Res 2006; 26: 1683-1689.
    • (2006) Anticancer Res , vol.26 , pp. 1683-1689
    • Koensgen, D.1    Mustea, A.2    Denkert, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.