-
1
-
-
33845699790
-
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
-
Hancock, R.E.; Sahl, H.G. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat. Biotechnol. 2006, 24, 1551-1557.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1551-1557
-
-
Hancock, R.E.1
Sahl, H.G.2
-
2
-
-
0035496012
-
Cationic peptides: Effectors in innate immunity and novel antimicrobials
-
Hancock, R.E. Cationic peptides: Effectors in innate immunity and novel antimicrobials. Lancet Infect. Dis. 2001, 1, 156-164.
-
(2001)
Lancet Infect. Dis.
, vol.1
, pp. 156-164
-
-
Hancock, R.E.1
-
3
-
-
0037165196
-
Antimicrobial peptides of multicellular organisms
-
Zasloff, M. Antimicrobial peptides of multicellular organisms. Nature 2002, 415, 389-395.
-
(2002)
Nature
, vol.415
, pp. 389-395
-
-
Zasloff, M.1
-
4
-
-
0030048076
-
Isolation of an ovine pulmonary surfactant-associated anionic peptide bactericidal for Pasteurella haemolytica
-
Brogden, K.A.; de Lucca, A.J.; Bland, J.; Elliott, S. Isolation of an ovine pulmonary surfactant-associated anionic peptide bactericidal for Pasteurella haemolytica. Proc. Natl. Acad. Sci. USA 1996, 93, 412-416.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 412-416
-
-
Brogden, K.A.1
De Lucca, A.J.2
Bland, J.3
Elliott, S.4
-
5
-
-
0036842381
-
Antimicrobial peptides from animals: Focus on invertebrates
-
Vizioli, J.; Salzet, M. Antimicrobial peptides from animals: Focus on invertebrates. Trends Pharmacol. Sci. 2002, 23, 494-496.
-
(2002)
Trends Pharmacol. Sci.
, vol.23
, pp. 494-496
-
-
Vizioli, J.1
Salzet, M.2
-
6
-
-
0037016020
-
Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7
-
Sadler, K.; Eom, K.D.; Yang, J.L.; Dimitrova, Y.; Tam, J.P. Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7. Biochemistry 2002, 41, 14150-14157.
-
(2002)
Biochemistry
, vol.41
, pp. 14150-14157
-
-
Sadler, K.1
Eom, K.D.2
Yang, J.L.3
Dimitrova, Y.4
Tam, J.P.5
-
7
-
-
0002560639
-
Magainins and the disruption of membrane-linked free-energy transduction
-
Westerhoff, H.V.; Juretić, D.; Hendler, R.W.; Zasloff, M. Magainins and the disruption of membrane-linked free-energy transduction. Proc. Natl. Acad. Sci. USA 1989, 86, 6597-6601.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 6597-6601
-
-
Westerhoff, H.V.1
Juretić, D.2
Hendler, R.W.3
Zasloff, M.4
-
8
-
-
0031984629
-
Platelet microbicidal proteins and neutrophil defensin disrupt the Staphylococcus aureus cytoplasmic membrane by distinct mechanisms of action
-
Yeaman, M.R.; Bayer, A.S.; Koo, S.P.; Foss, W.; Sullam, P.M. Platelet microbicidal proteins and neutrophil defensin disrupt the Staphylococcus aureus cytoplasmic membrane by distinct mechanisms of action. J. Clin. Investig. 1998, 101, 178-187.
-
(1998)
J. Clin. Investig.
, vol.101
, pp. 178-187
-
-
Yeaman, M.R.1
Bayer, A.S.2
Koo, S.P.3
Foss, W.4
Sullam, P.M.5
-
9
-
-
80053184140
-
The role of antimicrobial peptides in preventing multidrug-resistant bacterial infections and biofilm formation
-
Park, S.C.; Park, Y.; Hahm, K.S. The role of antimicrobial peptides in preventing multidrug-resistant bacterial infections and biofilm formation. Int. J. Mol. Sci. 2011, 12, 5971-5992.
-
(2011)
Int. J. Mol. Sci.
, vol.12
, pp. 5971-5992
-
-
Park, S.C.1
Park, Y.2
Hahm, K.S.3
-
10
-
-
84857411069
-
Designing antimicrobial peptides: Form follows function
-
Fjell, C.D.; Hiss, J.A.; Hancock, R.E.; Schneider, G. Designing antimicrobial peptides: Form follows function. Nat. Rev. Drug Discov. 2012, 11, 37-51.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 37-51
-
-
Fjell, C.D.1
Hiss, J.A.2
Hancock, R.E.3
Schneider, G.4
-
11
-
-
77957960555
-
Interaction between amphiphilic peptides and phospholipid membranes
-
Stromstedt, A.A.; Ringstad, L.; Schmidtchen, A.; Malmsten, M. Interaction between amphiphilic peptides and phospholipid membranes. Curr. Opin. Colloid Interface Sci. 2010, 15, 467-478.
-
(2010)
Curr. Opin. Colloid Interface Sci.
, vol.15
, pp. 467-478
-
-
Stromstedt, A.A.1
Ringstad, L.2
Schmidtchen, A.3
Malmsten, M.4
-
12
-
-
67650540782
-
Boosting antimicrobial peptides by hydrophobic oligopeptide end tags
-
Schmidtchen, A.; Pasupuleti, M.; Morgelin, M.; Davoudi, M.; Alenfall, J.; Chalupka, A.; Malmsten, M. Boosting antimicrobial peptides by hydrophobic oligopeptide end tags. J. Biol. Chem. 2009, 284, 17584-17594.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 17584-17594
-
-
Schmidtchen, A.1
Pasupuleti, M.2
Morgelin, M.3
Davoudi, M.4
Alenfall, J.5
Chalupka, A.6
Malmsten, M.7
-
13
-
-
84874221218
-
Targeted antimicrobial peptides
-
Devocelle, M. Targeted antimicrobial peptides. Front. Immunol. 2012, 3, 309.
-
(2012)
Front. Immunol.
, vol.3
, pp. 309
-
-
Devocelle, M.1
-
14
-
-
84921676971
-
-
Eds.; Cambridge University Press: New York, NY, USA
-
Mammalian Host Defence Peptides; Hancock, R., Devine, D., Eds.; Cambridge University Press: New York, NY, USA, 2004; pp. 39-68.
-
(2004)
Mammalian Host Defence Peptides
, pp. 39-68
-
-
Hancock, R.1
Devine, D.2
-
15
-
-
33745217570
-
The co-evolution of host cationic antimicrobial peptides and microbial resistance
-
Peschel, A.; Sahl, H.G. The co-evolution of host cationic antimicrobial peptides and microbial resistance. Nat. Rev. Microbiol. 2006, 4, 529-536.
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, pp. 529-536
-
-
Peschel, A.1
Sahl, H.G.2
-
16
-
-
2942670459
-
Can innate immunity be enhanced to treat microbial infections?
-
Finlay, B.B.; Hancock, R.E. Can innate immunity be enhanced to treat microbial infections? Nat. Rev. Microbiol. 2004, 2, 497-504.
-
(2004)
Nat. Rev. Microbiol.
, vol.2
, pp. 497-504
-
-
Finlay, B.B.1
Hancock, R.E.2
-
17
-
-
84871027267
-
A comprehensive summary of LL-37, the factotum human cathelicidin peptide
-
Vandamme, D.; Landuyt, B.; Luyten, W.; Schoofs, L. A comprehensive summary of LL-37, the factotum human cathelicidin peptide. Cell. Immunol. 2012, 280, 22-35.
-
(2012)
Cell. Immunol.
, vol.280
, pp. 22-35
-
-
Vandamme, D.1
Landuyt, B.2
Luyten, W.3
Schoofs, L.4
-
18
-
-
84856460625
-
Therapeutic potential of host defense peptides in antibiotic-resistant infections
-
Afacan, N.J.; Yeung, A.T.; Pena, O.M.; Hancock, R.E. Therapeutic potential of host defense peptides in antibiotic-resistant infections. Curr. Pharm. Des. 2012, 18, 807-819.
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 807-819
-
-
Afacan, N.J.1
Yeung, A.T.2
Pena, O.M.3
Hancock, R.E.4
-
19
-
-
84855865471
-
Emerging themes and therapeutic prospects for anti-infective peptides
-
Yount, N.Y.; Yeaman, M.R. Emerging themes and therapeutic prospects for anti-infective peptides. Annu. Rev. Pharmacol. Toxicol. 2012, 52, 337-360.
-
(2012)
Annu. Rev. Pharmacol. Toxicol.
, vol.52
, pp. 337-360
-
-
Yount, N.Y.1
Yeaman, M.R.2
-
20
-
-
0037768888
-
Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins
-
Taggart, C.C.; Greene, C.M.; Smith, S.G.; Levine, R.L.; McCray, P.B., Jr.; O'Neill, S.; McElvaney, N.G. Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins. J. Immunol. 2003, 171, 931-937.
-
(2003)
J. Immunol.
, vol.171
, pp. 931-937
-
-
Taggart, C.C.1
Greene, C.M.2
Smith, S.G.3
Levine, R.L.4
McCray, P.B.5
O'Neill, S.6
McElvaney, N.G.7
-
21
-
-
68949117860
-
LL-37 complexation with glycosaminoglycans in cystic fibrosis lungs inhibits antimicrobial activity, which can be restored by hypertonic saline
-
Bergsson, G.; Reeves, E.P.; McNally, P.; Chotirmall, S.H.; Greene, C.M.; Greally, P.; Murphy, P.; O'Neill, S.J.; McElvaney, N.G. LL-37 complexation with glycosaminoglycans in cystic fibrosis lungs inhibits antimicrobial activity, which can be restored by hypertonic saline. J. Immunol. 2009, 183, 543-551.
-
(2009)
J. Immunol.
, vol.183
, pp. 543-551
-
-
Bergsson, G.1
Reeves, E.P.2
McNally, P.3
Chotirmall, S.H.4
Greene, C.M.5
Greally, P.6
Murphy, P.7
O'Neill, S.J.8
McElvaney, N.G.9
-
22
-
-
84863994637
-
Beyond conventional antibiotics for the future treatment of methicillin-resistant Staphylococcus aureus infections: Two novel alternatives
-
Fitzgerald-Hughes, D.; Devocelle, M.; Humphreys, H. Beyond conventional antibiotics for the future treatment of methicillin-resistant Staphylococcus aureus infections: Two novel alternatives. FEMS Immunol. Med. Microbiol. 2012, 65, 399-412.
-
(2012)
FEMS Immunol. Med. Microbiol.
, vol.65
, pp. 399-412
-
-
Fitzgerald-Hughes, D.1
Devocelle, M.2
Humphreys, H.3
-
23
-
-
79960950287
-
Beyond natural antimicrobial peptides: Multimeric peptides and other peptidomimetic approaches
-
Giuliani, A.; Rinaldi, A.C. Beyond natural antimicrobial peptides: Multimeric peptides and other peptidomimetic approaches. Cell. Mol. Life Sci. 2011, 68, 2255-2266.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 2255-2266
-
-
Giuliani, A.1
Rinaldi, A.C.2
-
24
-
-
33947393032
-
Antimicrobial peptides: An overview of a promising class of therapeutics
-
Giuliani, A.; Pirri, G.; Nicoletto, S. Antimicrobial peptides: An overview of a promising class of therapeutics. Cent. Eur. J. Biol. 2007, 2, 1-33.
-
(2007)
Cent. Eur. J. Biol.
, vol.2
, pp. 1-33
-
-
Giuliani, A.1
Pirri, G.2
Nicoletto, S.3
-
25
-
-
0034727645
-
Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers
-
Zhang, L.; Scott, M.G.; Yan, H.; Mayer, L.D.; Hancock, R.E. Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers. Biochemistry 2000, 39, 14504-14514.
-
(2000)
Biochemistry
, vol.39
, pp. 14504-14514
-
-
Zhang, L.1
Scott, M.G.2
Yan, H.3
Mayer, L.D.4
Hancock, R.E.5
-
26
-
-
70350056559
-
Host defense peptides as effector molecules of the innate immune response: A sledgehammer for drug resistance?
-
Steinstraesser, L.; Kraneburg, U.M.; Hirsch, T.; Kesting, M.; Steinau, H.U.; Jacobsen, F.; Al-Benna, S. Host defense peptides as effector molecules of the innate immune response: A sledgehammer for drug resistance? Int. J. Mol. Sci. 2009, 10, 3951-3970.
-
(2009)
Int. J. Mol. Sci.
, vol.10
, pp. 3951-3970
-
-
Steinstraesser, L.1
Kraneburg, U.M.2
Hirsch, T.3
Kesting, M.4
Steinau, H.U.5
Jacobsen, F.6
Al-Benna, S.7
-
27
-
-
40149088986
-
Prodrugs: Design and clinical applications
-
Rautio, J.; Kumpulainen, H.; Heimbach, T.; Oliyai, R.; Oh, D.; Jarvinen, T.; Savolainen, J. Prodrugs: Design and clinical applications. Nat. Rev. Drug Discov. 2008, 7, 255-270.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 255-270
-
-
Rautio, J.1
Kumpulainen, H.2
Heimbach, T.3
Oliyai, R.4
Oh, D.5
Jarvinen, T.6
Savolainen, J.7
-
28
-
-
0035877995
-
Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3
-
Sorensen, O.E.; Follin, P.; Johnsen, A.H.; Calafat, J.; Tjabringa, G.S.; Hiemstra, P.S.; Borregaard, N. Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3. Blood 2001, 97, 3951-3959.
-
(2001)
Blood
, vol.97
, pp. 3951-3959
-
-
Sorensen, O.E.1
Follin, P.2
Johnsen, A.H.3
Calafat, J.4
Tjabringa, G.S.5
Hiemstra, P.S.6
Borregaard, N.7
-
29
-
-
84883311713
-
Sensitization of Gram-negative bacteria by targeting the membrane potential
-
Goldberg, K.; Sarig, H.; Zaknoon, F.; Epand, R.F.; Epand, R.M.; Mor, A. Sensitization of Gram-negative bacteria by targeting the membrane potential. FASEB J. 2013, 27, 3818-3826.
-
(2013)
FASEB J.
, vol.27
, pp. 3818-3826
-
-
Goldberg, K.1
Sarig, H.2
Zaknoon, F.3
Epand, R.F.4
Epand, R.M.5
Mor, A.6
-
30
-
-
17644389620
-
Colistin: The revival of polymyxins for the management of multidrug-resistant Gram-negative bacterial infections
-
Falagas, M.E.; Kasiakou, S.K. Colistin: The revival of polymyxins for the management of multidrug-resistant Gram-negative bacterial infections. Clin. Infect. Dis. 2005, 40, 1333-1341.
-
(2005)
Clin. Infect. Dis.
, vol.40
, pp. 1333-1341
-
-
Falagas, M.E.1
Kasiakou, S.K.2
-
31
-
-
84878293341
-
Pharmacology of polymyxins: New insights into an 'old' class of antibiotics
-
Velkov, T.; Roberts, K.D.; Nation, R.L.; Thompson, P.E.; Li, J. Pharmacology of polymyxins: New insights into an 'old' class of antibiotics. Future Microbiol. 2013, 8, 711-724.
-
(2013)
Future Microbiol.
, vol.8
, pp. 711-724
-
-
Velkov, T.1
Roberts, K.D.2
Nation, R.L.3
Thompson, P.E.4
Li, J.5
-
32
-
-
84877877188
-
Inhaled antibiotics for the treatment of chronic bronchopulmonary Pseudomonas aeruginosa infection in cystic fibrosis: Systematic review of randomised controlled trials
-
Maiz, L.; Giron, R.M.; Olveira, C.; Quintana, E.; Lamas, A.; Pastor, D.; Canton, R.; Mensa, J. Inhaled antibiotics for the treatment of chronic bronchopulmonary Pseudomonas aeruginosa infection in cystic fibrosis: Systematic review of randomised controlled trials. Expert Opin. Pharmacother. 2013, doi:10.1517/14656566.2013.790366.
-
(2013)
Expert Opin. Pharmacother.
-
-
Maiz, L.1
Giron, R.M.2
Olveira, C.3
Quintana, E.4
Lamas, A.5
Pastor, D.6
Canton, R.7
Mensa, J.8
-
33
-
-
84862523978
-
Challenges with current inhaled treatments for chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis
-
Greally, P.; Whitaker, P.; Peckham, D. Challenges with current inhaled treatments for chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis. Curr. Med. Res. Opin. 2012, 28, 1059-1067.
-
(2012)
Curr. Med. Res. Opin.
, vol.28
, pp. 1059-1067
-
-
Greally, P.1
Whitaker, P.2
Peckham, D.3
-
34
-
-
33744454666
-
Colistin methanesulfonate is an inactive prodrug of colistin against Pseudomonas aeruginosa
-
Bergen, P.J.; Li, J.; Rayner, C.R.; Nation, R.L. Colistin methanesulfonate is an inactive prodrug of colistin against Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 2006, 50, 1953-1958.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 1953-1958
-
-
Bergen, P.J.1
Li, J.2
Rayner, C.R.3
Nation, R.L.4
-
35
-
-
84872841018
-
Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: Iv. Colistimethate sodium
-
Young, D.C.; Zobell, J.T.; Waters, C.D.; Ampofo, K.; Stockmann, C.; Sherwin, C.M.; Spigarelli, M.G. Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: Iv. Colistimethate sodium. Pediatr. Pulmonol. 2013, 48, 1-7.
-
(2013)
Pediatr. Pulmonol.
, vol.48
, pp. 1-7
-
-
Young, D.C.1
Zobell, J.T.2
Waters, C.D.3
Ampofo, K.4
Stockmann, C.5
Sherwin, C.M.6
Spigarelli, M.G.7
-
36
-
-
0035118424
-
In vitro pharmacodynamic properties of colistin and colistin methanesulfonate against Pseudomonas aeruginosa isolates from patients with cystic fibrosis
-
Li, J.; Turnidge, J.; Milne, R.; Nation, R.L.; Coulthard, K. In vitro pharmacodynamic properties of colistin and colistin methanesulfonate against Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Antimicrob. Agents Chemother. 2001, 45, 781-785.
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 781-785
-
-
Li, J.1
Turnidge, J.2
Milne, R.3
Nation, R.L.4
Coulthard, K.5
-
37
-
-
11144229887
-
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
-
Jiang, T.; Olson, E.S.; Nguyen, Q.T.; Roy, M.; Jennings, P.A.; Tsien, R.Y. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc. Natl. Acad. Sci. USA 2004, 101, 17867-17872.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17867-17872
-
-
Jiang, T.1
Olson, E.S.2
Nguyen, Q.T.3
Roy, M.4
Jennings, P.A.5
Tsien, R.Y.6
-
38
-
-
79955540343
-
In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens
-
Desgranges, S.; le Prieult, F.; Daly, A.; Lydon, J.; Brennan, M.; Rai, D.K.; Subasinghage, A.P.; Hewage, C.M.; Cryan, S.A.; Greene, C.; et al. In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens. Antimicrob. Agents Chemother. 2011, 55, 2487-2489.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 2487-2489
-
-
Desgranges, S.1
Le Prieult, F.2
Daly, A.3
Lydon, J.4
Brennan, M.5
Rai, D.K.6
Subasinghage, A.P.7
Hewage, C.M.8
Cryan, S.A.9
Greene, C.10
-
39
-
-
84893519181
-
Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis
-
Forde, E.; Humphreys, H.; Greene, C.M.; Fitzgerald-Hughes, D.; Devocelle, M. Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis. Antimicrob. Agents Chemother. 2014, 58, 978-985.
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 978-985
-
-
Forde, E.1
Humphreys, H.2
Greene, C.M.3
Fitzgerald-Hughes, D.4
Devocelle, M.5
-
40
-
-
79955466299
-
Enhancement of the cancer targeting specificity of buforin IIb by fusion with an anionic peptide via a matrix metalloproteinases-cleavable linker
-
Jang, J.H.; Kim, M.Y.; Lee, J.W.; Kim, S.C.; Cho, J.H. Enhancement of the cancer targeting specificity of buforin IIb by fusion with an anionic peptide via a matrix metalloproteinases-cleavable linker. Peptides 2011, 32, 895-899.
-
(2011)
Peptides
, vol.32
, pp. 895-899
-
-
Jang, J.H.1
Kim, M.Y.2
Lee, J.W.3
Kim, S.C.4
Cho, J.H.5
-
41
-
-
0035884376
-
In vitro targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two gamma-linked glutamate residues at the COOH terminus
-
Warren, P.; Li, L.; Song, W.; Holle, E.; Wei, Y.; Wagner, T.; Yu, X. In vitro targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two gamma-linked glutamate residues at the COOH terminus. Cancer Res. 2001, 61, 6783-6787.
-
(2001)
Cancer Res.
, vol.61
, pp. 6783-6787
-
-
Warren, P.1
Li, L.2
Song, W.3
Holle, E.4
Wei, Y.5
Wagner, T.6
Yu, X.7
-
42
-
-
69249093854
-
In vivo targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two gamma-linked glutamate residues at the COOH terminus
-
Holle, L.; Song, W.; Holle, E.; Nilsson, J.; Wei, Y.; Li, J.; Wagner, T.E.; Yu, X. In vivo targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two gamma-linked glutamate residues at the COOH terminus. Mol. Med. Rep. 2009, 2, 399-403.
-
(2009)
Mol. Med. Rep.
, vol.2
, pp. 399-403
-
-
Holle, L.1
Song, W.2
Holle, E.3
Nilsson, J.4
Wei, Y.5
Li, J.6
Wagner, T.E.7
Yu, X.8
-
43
-
-
84875969630
-
Poly(ethylene glycol)-prodrug conjugates: Concept, design, and applications
-
Banerjee, S.S.; Aher, N.; Patil, R.; Khandare, J. Poly(ethylene glycol)-prodrug conjugates: Concept, design, and applications. J. Drug Deliv. 2012, 2012, doi:10.1155/2012/103973.
-
(2012)
J. Drug Deliv.
, vol.2012
-
-
Banerjee, S.S.1
Aher, N.2
Patil, R.3
Khandare, J.4
-
44
-
-
33747840618
-
Polymer conjugates as anticancer nanomedicines
-
Duncan, R. Polymer conjugates as anticancer nanomedicines. Nat. Rev. Cancer 2006, 6, 688-701.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 688-701
-
-
Duncan, R.1
-
45
-
-
0037362655
-
Effect of PEGylation on pharmaceuticals
-
Harris, J.M.; Chess, R.B. Effect of PEGylation on pharmaceuticals. Nat. Rev. Drug Discov. 2003, 2, 214-221.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 214-221
-
-
Harris, J.M.1
Chess, R.B.2
-
46
-
-
0344063545
-
Polyacetal-doxorubicin conjugates designed for pH-dependent degradation
-
Tomlinson, R.; Heller, J.; Brocchini, S.; Duncan, R. Polyacetal-doxorubicin conjugates designed for pH-dependent degradation. Bioconjugate Chem. 2003, 14, 1096-1106.
-
(2003)
Bioconjugate Chem.
, vol.14
, pp. 1096-1106
-
-
Tomlinson, R.1
Heller, J.2
Brocchini, S.3
Duncan, R.4
-
47
-
-
20844460357
-
PEG-doxorubicin conjugates: Influence of polymer structure on drug release, in vitro cytotoxicity, biodistribution, and antitumor activity
-
Veronese, F.M.; Schiavon, O.; Pasut, G.; Mendichi, R.; Andersson, L.; Tsirk, A.; Ford, J.; Wu, G.; Kneller, S.; Davies, J.; et al. PEG-doxorubicin conjugates: Influence of polymer structure on drug release, in vitro cytotoxicity, biodistribution, and antitumor activity. Bioconjugate Chem. 2005, 16, 775-784.
-
(2005)
Bioconjugate Chem.
, vol.16
, pp. 775-784
-
-
Veronese, F.M.1
Schiavon, O.2
Pasut, G.3
Mendichi, R.4
Andersson, L.5
Tsirk, A.6
Ford, J.7
Wu, G.8
Kneller, S.9
Davies, J.10
-
48
-
-
0023141221
-
Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro
-
Duncan, R.; Kopeckova-Rejmanova, P.; Strohalm, J.; Hume, I.; Cable, H.C.; Pohl, J.; Lloyd, J.B.; Kopecek, J. Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro. Br. J. Cancer 1987, 55, 165-174.
-
(1987)
Br. J. Cancer
, vol.55
, pp. 165-174
-
-
Duncan, R.1
Kopeckova-Rejmanova, P.2
Strohalm, J.3
Hume, I.4
Cable, H.C.5
Pohl, J.6
Lloyd, J.B.7
Kopecek, J.8
-
49
-
-
0037458920
-
Hpma copolymers with pH-controlled release of doxorubicin: In vitro cytotoxicity and in vivo antitumor activity
-
Ulbrich, K.; Etrych, T.; Chytil, P.; Jelinkova, M.; Rihova, B. Hpma copolymers with pH-controlled release of doxorubicin: In vitro cytotoxicity and in vivo antitumor activity. J. Control. Release 2003, 87, 33-47.
-
(2003)
J. Control. Release
, vol.87
, pp. 33-47
-
-
Ulbrich, K.1
Etrych, T.2
Chytil, P.3
Jelinkova, M.4
Rihova, B.5
-
50
-
-
34047271928
-
Action mechanism of tachyplesin I and effects of PEGylation
-
Imura, Y.; Nishida, M.; Ogawa, Y.; Takakura, Y.; Matsuzaki, K. Action mechanism of tachyplesin I and effects of PEGylation. Biochim. Biophys. Acta 2007, 1768, 1160-1169.
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 1160-1169
-
-
Imura, Y.1
Nishida, M.2
Ogawa, Y.3
Takakura, Y.4
Matsuzaki, K.5
-
51
-
-
34948886156
-
Action mechanism of PEGylated magainin 2 analogue peptide
-
Imura, Y.; Nishida, M.; Matsuzaki, K. Action mechanism of PEGylated magainin 2 analogue peptide. Biochim. Biophys. Acta 2007, 1768, 2578-2585.
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 2578-2585
-
-
Imura, Y.1
Nishida, M.2
Matsuzaki, K.3
-
52
-
-
84898652791
-
Effects of PEGylation on membrane and lipopolysaccharide interactions of host defense peptides
-
Singh, S.; Papareddy, P.; Morgelin, M.; Schmidtchen, A.; Malmsten, M. Effects of PEGylation on membrane and lipopolysaccharide interactions of host defense peptides. Biomacromolecules 2014, 15, 1337-1345.
-
(2014)
Biomacromolecules
, vol.15
, pp. 1337-1345
-
-
Singh, S.1
Papareddy, P.2
Morgelin, M.3
Schmidtchen, A.4
Malmsten, M.5
-
53
-
-
84861133663
-
PEGylation of antimicrobial peptides maintains the active peptide conformation, model membrane interactions, and antimicrobial activity while improving lung tissue biocompatibility following airway delivery
-
Morris, C.J.; Beck, K.; Fox, M.A.; Ulaeto, D.; Clark, G.C.; Gumbleton, M. PEGylation of antimicrobial peptides maintains the active peptide conformation, model membrane interactions, and antimicrobial activity while improving lung tissue biocompatibility following airway delivery. Antimicrob. Agents Chemother. 2012, 56, 3298-3308.
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 3298-3308
-
-
Morris, C.J.1
Beck, K.2
Fox, M.A.3
Ulaeto, D.4
Clark, G.C.5
Gumbleton, M.6
-
54
-
-
57749180588
-
Modification of antimicrobial peptide with low molar mass poly(ethylene glycol)
-
Zhang, G.; Han, B.; Lin, X.; Wu, X.; Yan, H. Modification of antimicrobial peptide with low molar mass poly(ethylene glycol). J. Biochem. 2008, 144, 781-788.
-
(2008)
J. Biochem.
, vol.144
, pp. 781-788
-
-
Zhang, G.1
Han, B.2
Lin, X.3
Wu, X.4
Yan, H.5
-
55
-
-
84880124033
-
Controlled systemic release of therapeutic peptides from PEGylated prodrugs by serum proteases
-
Nollmann, F.I.; Goldbach, T.; Berthold, N.; Hoffmann, R. Controlled systemic release of therapeutic peptides from PEGylated prodrugs by serum proteases. Angew. Chem. Int. Ed. Engl. 2013, 52, 7597-7599.
-
(2013)
Angew. Chem. Int. Ed. Engl.
, vol.52
, pp. 7597-7599
-
-
Nollmann, F.I.1
Goldbach, T.2
Berthold, N.3
Hoffmann, R.4
-
57
-
-
59349093299
-
Targeted antimicrobial activity of a specific IgG-SMAP28 conjugate against Porphyromonas gingivalis in a mixed culture
-
Franzman, M.R.; Burnell, K.K.; Dehkordi-Vakil, F.H.; Guthmiller, J.M.; Dawson, D.V.; Brogden, K.A. Targeted antimicrobial activity of a specific IgG-SMAP28 conjugate against Porphyromonas gingivalis in a mixed culture. Int. J. Antimicrob. Agents 2009, 33, 14-20.
-
(2009)
Int. J. Antimicrob. Agents
, vol.33
, pp. 14-20
-
-
Franzman, M.R.1
Burnell, K.K.2
Dehkordi-Vakil, F.H.3
Guthmiller, J.M.4
Dawson, D.V.5
Brogden, K.A.6
-
58
-
-
33746141286
-
Design of a peptibody consisting of the antimicrobial peptide dhvar5 and a llama variable heavy-chain antibody fragment
-
Szynol, A.; de Haard, J.J.; Veerman, E.C.; de Soet, J.J.; van Nieuw Amerongen, A.V. Design of a peptibody consisting of the antimicrobial peptide dhvar5 and a llama variable heavy-chain antibody fragment. Chem. Biol. Drug Des. 2006, 67, 425-431.
-
(2006)
Chem. Biol. Drug Des.
, vol.67
, pp. 425-431
-
-
Szynol, A.1
De Haard, J.J.2
Veerman, E.C.3
De Soet, J.J.4
Van Nieuw Amerongen, A.V.5
-
59
-
-
33750584025
-
Targeted killing of Streptococcus mutans by a pheromone-guided "smart" antimicrobial peptide
-
Eckert, R.; He, J.; Yarbrough, D.K.; Qi, F.; Anderson, M.H.; Shi, W. Targeted killing of Streptococcus mutans by a pheromone-guided "smart" antimicrobial peptide. Antimicrob. Agents Chemother. 2006, 50, 3651-3657.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 3651-3657
-
-
Eckert, R.1
He, J.2
Yarbrough, D.K.3
Qi, F.4
Anderson, M.H.5
Shi, W.6
-
60
-
-
10744228928
-
An engineered multidomain bactericidal peptide as a model for targeted antibiotics against specific bacteria
-
Qiu, X.Q.; Wang, H.; Lu, X.F.; Zhang, J.; Li, S.F.; Cheng, G.; Wan, L.; Yang, L.; Zuo, J.Y.; Zhou, Y.Q.; et al. An engineered multidomain bactericidal peptide as a model for targeted antibiotics against specific bacteria. Nat. Biotechnol. 2003, 21, 1480-1485.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1480-1485
-
-
Qiu, X.Q.1
Wang, H.2
Lu, X.F.3
Zhang, J.4
Li, S.F.5
Cheng, G.6
Wan, L.7
Yang, L.8
Zuo, J.Y.9
Zhou, Y.Q.10
-
61
-
-
14744272033
-
A novel engineered peptide, a narrow-spectrum antibiotic, is effective against vancomycin-resistant Enterococcus faecalis
-
Qiu, X.Q.; Zhang, J.; Wang, H.; Wu, G.Y. A novel engineered peptide, a narrow-spectrum antibiotic, is effective against vancomycin-resistant Enterococcus faecalis. Antimicrob. Agents Chemother. 2005, 49, 1184-1189.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 1184-1189
-
-
Qiu, X.Q.1
Zhang, J.2
Wang, H.3
Wu, G.Y.4
-
62
-
-
64549112594
-
Design and activity of a "dual-targeted" antimicrobial peptide
-
He, J.; Anderson, M.H.; Shi, W.; Eckert, R. Design and activity of a "dual-targeted" antimicrobial peptide. Int. J. Antimicrob. Agents 2009, 33, 532-537.
-
(2009)
Int. J. Antimicrob. Agents
, vol.33
, pp. 532-537
-
-
He, J.1
Anderson, M.H.2
Shi, W.3
Eckert, R.4
-
63
-
-
84863097110
-
Enhanced membrane pore formation through high-affinity targeted antimicrobial peptides
-
Arnusch, C.J.; Pieters, R.J.; Breukink, E. Enhanced membrane pore formation through high-affinity targeted antimicrobial peptides. PLoS One 2012, 7, e39768.
-
(2012)
PLoS One
, vol.7
, pp. e39768
-
-
Arnusch, C.J.1
Pieters, R.J.2
Breukink, E.3
-
64
-
-
84859133287
-
Beta-lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria
-
Desgranges, S.; Ruddle, C.C.; Burke, L.P.; McFadden, T.M.; O'Brien, J.E.; Fitzgerald-Hughes, D.; Humphreys, H.; Smyth, T.P.; Devocelle, M. Beta-lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria. RSC Adv. 2012, 2, 2480-2492.
-
(2012)
RSC Adv.
, vol.2
, pp. 2480-2492
-
-
Desgranges, S.1
Ruddle, C.C.2
Burke, L.P.3
McFadden, T.M.4
O'Brien, J.E.5
Fitzgerald-Hughes, D.6
Humphreys, H.7
Smyth, T.P.8
Devocelle, M.9
-
65
-
-
82255179791
-
Synthesis of mutual azo prodrugs of anti-inflammatory agents and peptides facilitated by alpha-aminoisobutyric acid
-
Kennedy, D.A.; Vembu, N.; Fronczek, F.R.; Devocelle, M. Synthesis of mutual azo prodrugs of anti-inflammatory agents and peptides facilitated by alpha-aminoisobutyric acid. J. Org. Chem. 2011, 76, 9641-9647.
-
(2011)
J. Org. Chem.
, vol.76
, pp. 9641-9647
-
-
Kennedy, D.A.1
Vembu, N.2
Fronczek, F.R.3
Devocelle, M.4
|